Development and evaluation of a multi-epitope subunit vaccine against group B Streptococcus infection

References

• Raabe VN, Shane AL. Group B Streptococcus (Streptococcus agalactiae). Microbiol Spectr. 2019 Mar;7(2):1–13.
   Web of Science ®Google Scholar
• McGee L, Chochua S, Li Z, et al. Multistate, population-based distributions of candidate vaccine targets, clonal complexes, and resistance features of invasive group B streptococci within the United States, 2015-2017. Clin Infect Dis. 2021 Mar 15;72(6):1004–1013.
   PubMed Web of Science ®Google Scholar
• WHO. Full value of vaccine assessment. World Health Organization; 2021.
   Google Scholar
• Xu DH, Shoemaker CA, Klesius PH. Enhanced mortality in Nile tilapia Oreochromis niloticus following coinfections with ichthyophthiriasis and streptococcosis. Dis Aquat Organ. 2009 Jul 23;85(3):187–192.
   PubMed Web of Science ®Google Scholar
• Tan S, Lin Y, Foo K, et al. Group B Streptococcus serotype III sequence type 283 bacteremia associated with consumption of raw fish, Singapore. Emerg Infect Dis. 2016 Nov;22(11):1970–1973.
   PubMed Web of Science ®Google Scholar
• Bedeley E, Gori A, Yeboah-Manu D, et al. Control of streptococcal infections: is a common vaccine target achievable against Streptococcus agalactiae and Streptococcus pneumoniae. Front Microbiol. 2021 Apr 23;12:1–9.
   Web of Science ®Google Scholar
• Baker CJ. The spectrum of perinatal group B streptococcal disease. Vaccine. 2013 Aug 28;31(Suppl 4):D3–D6.
   PubMedGoogle Scholar
• Baker CJ, Rench MA, Edwards MS, et al. Immunization of pregnant women with a polysaccharide vaccine of group B Streptococcus. N Engl J Med. 1988 Nov 3;319(18):1180–1185.
   PubMed Web of Science ®Google Scholar
• Kasper DL, Paoletti LC, Wessels MR, et al. Immune response to type III group B streptococcal polysaccharide-tetanus toxoid conjugate vaccine. J Clin Invest. 1996 Nov 15;98(10):2308–2314.
   PubMed Web of Science ®Google Scholar
• Absalon J, Segall N, Block SL, et al. Safety and immunogenicity of a novel hexavalent group B streptococcus conjugate vaccine in healthy, non-pregnant adults: a phase 1/2, randomised, placebo-controlled, observer-blinded, dose-escalation trial. Lancet Infect Dis. 2021 Feb;21(2):263–274.
   PubMed Web of Science ®Google Scholar
• Absalon J, Simon R, Radley D, et al. Advances towards licensure of a maternal vaccine for the prevention of invasive group B streptococcus disease in infants: a discussion of different approaches. Hum Vaccin Immunother. 2022 Dec 31;18(1):2037350.
   PubMed Web of Science ®Google Scholar
• Kobayashi M, Schrag SJ, Alderson MR, et al. WHO consultation on group B Streptococcus vaccine development: report from a meeting held on 27-28 April 2016. Vaccine. 2019 Nov 28;37(50):7307–7314.
   PubMed Web of Science ®Google Scholar
• Martin D, Rioux S, Gagnon E, et al. Protection from group B streptococcal infection in neonatal mice by maternal immunization with recombinant Sip protein. Infect Immun. 2002 Sep;70(9):4897–4901.
   PubMed Web of Science ®Google Scholar
• Meinke AL, Senn BM, Visram Z, et al. Immunological fingerprinting of group B streptococci: from circulating human antibodies to protective antigens. Vaccine. 2010 Oct 8;28(43):6997–7008.
   PubMed Web of Science ®Google Scholar
• Soleymani S, Tavassoli A, Housaindokht MR. An overview of progress from empirical to rational design in modern vaccine development, with an emphasis on computational tools and immunoinformatics approaches. Comput Biol Med. 2021 Nov 24;140:105057.
   PubMed Web of Science ®Google Scholar
• Oli AN, Obialor WO, Ifeanyichukwu MO, et al. Immunoinformatics and vaccine development: an overview. Immunotargets Ther. 2020;9:13–30.
   PubMed Web of Science ®Google Scholar
• Vakili B, Eslami M, Hatam GR, et al. Immunoinformatics-aided design of a potential multi-epitope peptide vaccine against Leishmania infantum. Int J Biol Macromol. 2018 Dec;120(Pt A):1127–1139.
   PubMedGoogle Scholar
• Ahmad I, Ali SS, Zafar B, et al. Development of multi-epitope subunit vaccine for protection against the norovirus’ infections based on computational vaccinology. J Biomol Struct Dyn. 2022 Apr;40(7):3098–3109.
   PubMed Web of Science ®Google Scholar
• Soltan MA, Magdy D, Solyman SM, et al. Design of Staphylococcus aureus new vaccine candidates with B and T cell epitope mapping, reverse vaccinology, and immunoinformatics. OMICS. 2020 Apr;24(4):195–204.
   PubMed Web of Science ®Google Scholar
• Nosrati M, Hajizade A, Nazarian S, et al. Designing a multi-epitope vaccine for cross-protection against Shigella spp: an immunoinformatics and structural vaccinology study. Mol Immunol. 2019 Dec;116:106–116.
   PubMed Web of Science ®Google Scholar
• Liu G, Zhang W, Lu C. Identification of immunoreactive proteins of Streptococcus agalactiae isolated from cultured tilapia in China. Pathog Dis. 2013 Dec;69(3):223–231.
   PubMed Web of Science ®Google Scholar
• Saha S, Raghava GP. Prediction of continuous B-cell epitopes in an antigen using recurrent neural network. Proteins. 2006 Oct 1;65(1):40–48.
   PubMed Web of Science ®Google Scholar
• Saha S, Raghava GPS. Bcepred: prediction of continuous B-cell epitopes in antigenic sequences using physico-chemical properties. Lect Notes Comput Sc. 2004;3239:197–204.
   Google Scholar
• Mamede LD, de Paula KG, de Oliveira B, et al. Reverse and structural vaccinology approach to design a highly immunogenic multi-epitope subunit vaccine against Streptococcus pneumoniae infection. Infect Genet Evol. 2020 Nov;85:104473.
   PubMed Web of Science ®Google Scholar
• Doytchinova IA, Flower DR. Vaxijen: a server for prediction of protective antigens, tumour antigens and subunit vaccines. BMC Bioinformatics. 2007 Jan 5;8(4):4.
   PubMedGoogle Scholar
• Wilkins MR, Gasteiger E, Bairoch A, et al. Protein identification and analysis tools in the ExPASy server. Methods Mol Biol. 1999;112:531–552.
   PubMedGoogle Scholar
• Livingston B, Crimi C, Newman M, et al. A rational strategy to design multiepitope immunogens based on multiple TH lymphocyte epitopes. J Immunol. 2002 Jun 1;168(11):5499–5506.
   PubMed Web of Science ®Google Scholar
• Humphreys RE, Adams S, Koldzic G, et al. Increasing the potency of MHC class II-presented epitopes by linkage to Ii-Key peptide. Vaccine. 2000 Jun 1;18(24):2693–2697.
   PubMed Web of Science ®Google Scholar
• Saha S, Raghava GP. Algpred: prediction of allergenic proteins and mapping of IgE epitopes. Nucleic Acids Res. 2006 Jul 1;34(Web Server issue):W202–W209.
   PubMed Web of Science ®Google Scholar
• Roy A, Kucukural A, Zhang Y. I-TASSER: a unified platform for automated protein structure and function prediction. Nat Protoc. 2010 Apr;5(4):725–738.
   PubMed Web of Science ®Google Scholar
• Ko J, Park H, Heo L, et al. GalaxyWEB server for protein structure prediction and refinement. Nucleic Acids Res. 2012 Jul;40(Web Server issue):W294–W297.
   PubMed Web of Science ®Google Scholar
• Wiederstein M, Sippl MJ. ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins. Nucleic Acids Res. 2007 Jul;35(Web Server issue):W407–W410.
   PubMed Web of Science ®Google Scholar
• Laskowski RA, Rullmannn JA, MacArthur MW, et al. AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR. J Biomol NMR. 1996 Dec;8(4):477–486.
   PubMed Web of Science ®Google Scholar
• Kozakov D, Hall DR, Xia B, et al. The ClusPro web server for protein-protein docking. Nat Protoc. 2017 Feb;12(2):255–278.
   PubMed Web of Science ®Google Scholar
• Laskowski RA. PDBsum: summaries and analyses of PDB structures. Nucleic Acids Res. 2001 Jan 1;29(1):221–222.
   PubMed Web of Science ®Google Scholar
• Rapin N, Lund O, Bernaschi M, et al. Computational immunology meets bioinformatics: the use of prediction tools for molecular binding in the simulation of the immune system. Plos One. 2010 Apr 16;5(4):e9862.
   PubMed Web of Science ®Google Scholar
• Castiglione F, Mantile F, De Berardinis P, et al. How the interval between prime and boost injection affects the immune response in a computational model of the immune system. Comput Math Method M. 2012;2012:9.
   Web of Science ®Google Scholar
• Liu G, Zhang W, Lu C. Complete genome sequence of Streptococcus agalactiae GD201008-001, isolated in China from tilapia with meningoencephalitis. J Bacteriol. 2012 Dec;194(23):6653.
   PubMed Web of Science ®Google Scholar
• Babu L, Uppalapati SR, Sripathy MH, et al. Evaluation of recombinant multi-epitope outer membrane protein-based Klebsiella pneumoniae subunit vaccine in mouse model. Front Microbiol. 2017 Sep 20;8:1805.
   PubMed Web of Science ®Google Scholar
• Leykun Y, Genet C, Mulu W. Group B streptococci vaginal-recto colonization, vertical transmission to newborns, antimicrobial susceptibility profile and associated factors in selected health facilities of bahir Dar city: a cross-sectional study. Infect Drug Resist. 2021;14:5457–5472.
   PubMed Web of Science ®Google Scholar
• Bahrami AA, Payandeh Z, Khalili S, et al. Immunoinformatics: in silico approaches and computational design of a multi-epitope, immunogenic protein. Int Rev Immunol. 2019;38(6):307–322.
   PubMed Web of Science ®Google Scholar
• Vernikos G, Medini D. Bexsero(R) chronicle. Pathog Glob Health. 2014 Oct;108(7):305–316.
   PubMed Web of Science ®Google Scholar
• Ren S, Guan L, Dong Y, et al. Design and evaluation of a multi-epitope assembly peptide vaccine against Acinetobacter baumannii infection in mice. Swiss Med Wkly. 2019 Jun 3;149:w20052.
   PubMed Web of Science ®Google Scholar
• Hurtgen BJ, Hung CY, Ostroff GR, et al. Construction and evaluation of a novel recombinant T cell epitope-based vaccine against Coccidioidomycosis. Infect Immun. 2012 Nov;80(11):3960–3974.
   PubMed Web of Science ®Google Scholar
• Pumchan A, Krobthong S, Roytrakul S, et al. Novel chimeric multiepitope vaccine for Streptococcosis disease in Nile tilapia (Oreochromis niloticus Linn. Sci Rep. 2020 Jan 17;10(1):603.
   PubMed Web of Science ®Google Scholar
• Liu G, Gao T, Zhong X, et al. The novel streptococcal transcriptional regulator XtgS negatively regulates bacterial virulence and directly represses PseP transcription. Infect Immun. 2020 Sep 18;88(10):e00035-20.
   PubMed Web of Science ®Google Scholar