RP-HPLC PDA Analysis of Tranexamic Acid in Bulk and Tablet Dosage Form

References

• Dunn, C.J. and Goa, K.L. (1999). Tranexamic acid. Drugs. 57: 1005. doi: 10.2165/00003495-199957060-00017
   Google Scholar
• Boylan, J.F., Klinck, J.R., Sandler, A.N., Arellano, R., Greig, P.D., Nierenberg, H., Roger, S.L. and Glynn, M.F. (1996). Tranexamic acid reduces blood loss, transfusion requirements, and coagulation factor use in primary orthotopic liver transplantation. The Journal of the American Society of Anesthesiologists. 85: 1043.
   Google Scholar
• Hiippala, S.T., Strid, L.J., Wennerstrand, M.I., Arvela, J.V.V., Niemela, H.M., Mantyla, S.K., Kuisma, R.P. and Ylinen, J.E. (1997). Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty. Anesth. Analg. 84: 839. doi: 10.1213/00000539-199704000-00026
   Google Scholar
• Hoylaerts, M., Lijnen, H.R., and Collen, D. (1981). Studies on the mechanism of the antifibrinolytic action of tranexamic acid. Biochimica et Biophysica Acta (BBA)-General Subjects. 673: 75. doi: 10.1016/0304-4165(81)90312-3
   Google Scholar
• Ashfaq, M., Aslam, A., Mustafa, G., Danish, M., Nazar, M.F. and Asghar, M.N. (2015). Derivatization/chromophore introduction of tranexamic acid and its HPLC determination in pharmaceutical formulations. Journal of the Association of Arab Universities for Basic and Applied Sciences. 17: 51. doi: 10.1016/j.jaubas.2014.02.005
   Google Scholar
• Natesan, S., Thanasekaran, D., Krishnaswami, V. and Ponnusamy, C. (2011). Improved RP-HPLC Method for the Simultaneous Estimation of Tranexamic Acid and Mefenamic Acid in Tablet Dosage Form. Pharmaceutica Analytica Acta. 2: 115. doi: 10.4172/2153-2435.1000115
   Google Scholar
• Matsubayashi, K., Kojima, C. and Tachizawa, H. (1988). Determination of tranexamic acid in human serum by high-performance liquid chromatography using selective pre-column derivatization with phenyl isothiocyanate.Journal of Chromatography B: Biomedical Sciences and Applications. 433: 225. doi: 10.1016/S0378-4347(00)80601-5
   Google Scholar
• Hadad, G.M., El-Gindy, A. and Mahmoud, W.M.M. (2007). Optimization and Validation of an HPLC-UV Method for Determination of Tranexamic Acid in a Dosage Form and in Human Urine. Chromatographia. 66: 311. doi: 10.1365/s10337-007-0323-6
   Google Scholar
• Khuhawar, M. and Rind, F. (2001). HPLC determination of tranexamic acid in pharmaceutical preparations and blood. Chromatographia. 53: 709. doi: 10.1007/BF02493025
   Google Scholar
• Nojiri, S., Uehara, S., Hagiwara, T. and Nishijima, M. (1995). Highperformance liquid chromatographic determination of aspartic acid, taurine, and tranexamic acid by precolumn derivatization using sodium picrylsulfonate. Tokyo-toritsu Eisei Kenkyusho Kenkyu Nenpo. 46: 58.
   Google Scholar
• Huertas-Pérez, J.F., Heger, M., Dekker, H., Krabbe, H., Lankelma, J., and Ariese, F. (2007). Simple, rapid, and sensitive liquid chromatography-fluorescence method for the quantification of tranexamic acid in blood. J. Chromatogr. A. 1157: 142. doi: 10.1016/j.chroma.2007.04.067
   Google Scholar
• Sato, K., Tobita, Y., Iwabuchi, K. and Tanaka, S. (1997). Determination of Tranexamic Acid and Vitamins by High Performance Liquid Chromatography with Peroxyoxalate Chemilumine-scence Detection. Anal. Sci. 13: 471. doi: 10.2116/analsci.13.Supplement_471
   Google Scholar
• Chang, Q., Yin, O.Q. and Chow, M.S. (2004). Liquid chromatography-tandem mass spectrometry method for the determination of tranexamic acid in human plasma. J. Chromatogr. B. 805: 275. doi: 10.1016/j.jchromb.2004.03.013
   Google Scholar
• Abou-Diwan, C., Sniecinski, R.M., Szlam, F., Ritchie, J.C., Rhea, J.M., Tanaka, K.A. and Molinaro, R.J. (2011). Plasma and cerebral spinal fluid tranexamic acid quantitation in cardiopulmonary bypass patients. J. Chromatogr. B. 879: 553. doi: 10.1016/j.jchromb.2011.01.005
   Google Scholar
• Vessman, J. and Stromberg, S. (1977). Determination of tranexamic acid in biological material by electron capture gas chromatography after direct derivatization in an aqueous medium. Anal. Chem. 49: 369. doi: 10.1021/ac50011a012
   Google Scholar
• Jain, P.S., Chaudhari, A.J. and Surana, S.J. (2013). Selective High Performance Liquid Chromatographic Determination of Amodiaquine and Artesunate in bulk and pharmaceutical formulation. J. App. Pharm. Sci. 3: 066.
   Google Scholar
• ICH (Q2B) Note for guidance on validation of analytical procedures: methodology. in International conference on Harmonisation. IFPMA, Geneva: 1996.
   Google Scholar
• Guidance, R. (1994). Validation of chromatographic methods.Center for Drug Evaluation and Research, Food and Drug Administration, http://www.fda.gov/downloads/Drugs/Guidances/UCM134409.pdf:669.
   Google Scholar