Anticancer activity of Indonesian Melia azedarach L.: Phyto-chemistry, in vitro and in silico studies

References

• World Health Organization W. (2016). Global health estimates 2015: deaths by cause, age, sex, by country and by region, 2000-2015. J Geneva: WHO:2016.
   Google Scholar
• Lakshmi, M. (2020). Plant-Based Drugs as an Adjuvant to Cancer Chemotherapy. In: Muhammad A, editor. Alternative Medicine. Rijeka: IntechOpen; p. Ch. 16.
   Google Scholar
• Cragg, G.M., Newman, D.J. (2005). Plants as a source of anti-cancer agents. Journal of Ethnopharmacology. 100(1): 72-79. doi: 10.1016/j.jep.2005.05.011
   PubMed Web of Science ®Google Scholar
• Taneja, S.C., Qazi, G.N. (2007). Bioactive Molecules in Medicinal Plants: A Perspective on their Therapeutic Action. Drug Discovery and Development. 1-50.
   Google Scholar
• Choudhari, A.S., Mandave, P.C., Desh-pande, M., Ranjekar, P., Prakash, O. (2020). Phytochemicals in Cancer Treatment: From Preclinical Studies to Clinical Practice [Review]. Frontiers in Pharmacology. 10. 1614. doi: 10.3389/fphar.2019.01614
   PubMed Web of Science ®Google Scholar
• Al-Rubae, A.Y. (2009). The potential uses of Melia azedarach L. as pesticidal and medicinal plant, review. American-Eurasian Journal of Sustainable Agriculture. 3(2): 185-194.
   Google Scholar
• Dalimartha, S. (2003). Atlas Tumbuhan Obat Indonesia, Jilid III. Puspa Swara. Jakarta.
   Google Scholar
• Syamsuhidayat, S.S., Hutapea, J.R. (1991). Inventaris tanaman obat Indonesia. Depar-temen Kesehatan RI, Jakarta. 1: 286-287.
   Google Scholar
• Hutapea, J.R. (2000). Inventaris tanaman obat Indonesia I jilid 1. Jakarta: Departemen Kesehatan dan Kesejahteraan Sosial RI.
   Google Scholar
• Sharma, D., Dr, Y.P. (2013). Preliminary and pharmacological profile of Melia azedarach L.: An overview. Journal of Applied Pharmaceutical Science. 3: 133-138.
   Google Scholar
• Kumar, R., Singh, R.M., Meera, P.S., Kalidhar, S.B.J.A.R. (2003). Chemical components and insecticidal properties of Bakain (Melia azedarach L.) – A review. 24: 101-115.
   Google Scholar
• Suresh, K. (2008). Antimicrobial and Phytochemical Investigation of the Leaves of Carica papaya L., Cynodon dactylon (L.) Pers., Euphorbia hirta L., Melia azedarach L. and Psidium guajava L. Ethnobotanical Leaflets. 2008: 157.
   Google Scholar
• Akihisa, T., Pan, X., Fau-Nakamura, Y., Nakamura, Y., Fau-Kikuchi, T., Kikuchi, T., Fau-Takahashi, N, Takahashi, N Fau-Matsumoto, M, Matsumoto, M Fau-Ogihara, E., Ogihara, E., Fau-Fukatsu, M., Fukatsu, M., Fau-Koike, K., Koike, K., Fau-Tokuda, H., Tokuda, H. (2013). Limonoids from the fruits of Melia azedarach and their cytotoxic activities. Phytochemistry. 89: 59-70. doi: 10.1016/j.phytochem.2013.01.015
   PubMed Web of Science ®Google Scholar
• He, Y., Wang, J., Fau-Liu, X., Liu, X., Fau-Zhang, L., Zhang, L., Fau-Yi, G., Yi, G., Fau-Li, C., Li, C., Fau-He, X., He, X., Fau-Wang, P., Wang, P., Fau-Jiang, H., Jiang, H. (2010). Toosendanin inhibits hepatocellular carcinoma cells by inducing mitochondria-dependent apoptosis. Planta medica. 76(13): 1447-1453. doi: 10.1055/s-0029-1240902
   PubMedGoogle Scholar
• Ervina, M., Poerwono, H., Widyowati, R., Matsunami, K., Sukardiman. (2020). Bio-selective hormonal breast cancer cytotoxic and antioxidant potencies of Melia azedarach L. wild type leaves. Biotechnology reports (Amsterdam, Netherlands). 25(e00437).
   Google Scholar
• Ervina, M., Poerwono, H., Widyowati, R., Otsuka, H., Matsunami, K., Sukardiman, S. (2021). Pregnane Steroids from the Leaves of Melia azedarach and Apoptotic Activity against T47D Cells. Asian Pacific journal of Cancer Prevention : APJCP, 22(6): 1967-1973. doi: 10.31557/APJCP.2021.22.6.1967
   PubMedGoogle Scholar
• The Plant List Version 1 [Internet]. 2010 [cited 3rd January 2020]. Available from: http://www.theplantlist.org/.
   Google Scholar
• Nugraha, A.S., Purnomo, Y.D., Widhi Pratama, A.N., Triatmoko, B., Hendra, R., Wongso, H., Avery, V.M., Keller, P.A. (2022). Isolation of Antimalarial Agents From Indonesian Medicinal Plants: Swietenia mahagoni and Pluchea indica. Natural Product Communications. 17(1): 1934578X211068926. doi: 10.1177/1934578X211068926
   Google Scholar
• Hendra, R., Keller, P.A. (2016). Flowers in Australia: phytochemical studies on the Illa-warra flame tree and Alstonville. Australian Journal of Chemistry. 69(8): 925-927. doi: 10.1071/CH16058
   Google Scholar
• Thota, S., Sarma, N., Murthy, Y., Kanta-mreddi, V., Wright, C. (2016). A new embelin from the mangrove Aegiceras corniculatum. Indian Journal of Chemistry Section B. 55(1): 123-127.
   Google Scholar
• Mosmann, T. (1983). Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. Journal of Immunological Methods. 65(1): 55-63. doi: 10.1016/0022-1759(83)90303-4
   PubMed Web of Science ®Google Scholar
• Kashyap, D., Sharma, A., Tuli, H.S., Sak, K., Punia, S., Mukherjee, T.K. (2017).Kaempferol - A dietary anticancer molecule with multiple mechanisms of action: Recent trends and advancements. J. Funct. Foods. 30: 203-219. doi: 10.1016/j.jff.2017.01.022
   PubMed Web of Science ®Google Scholar
• Jafari, S., Saeidnia, S., Hajimehdipoor, H., Ardekani, M.R.S., Faramarzi, M.A., Hadjiakhoondi, A., Khanavi, M. (2013). Cytotoxic evaluation of Melia azedarach in comparison with, Azadirachta indica and its phytochemical investigation. DARU Journal of Pharmaceutical Sciences. 21: 1-7. doi: 10.1186/2008-2231-21-37
   Google Scholar
• Yao, C., Jin, C.L, Oh, I.G., Park, C.H., Chung, J.H. (2015). Melia azedarach extract stimulates melanogenesis through increase of tyrosinase-related protein 1 expression in B16F10 mouse melanoma cells. Int. J. Mol. Med. 35(6): 1761-6. doi: 10.3892/ijmm.2015.2182
   PubMedGoogle Scholar
• Wu, S-B., Ji, Y-P., Zhu, J-J., Zhao, Y., Xia, G., Hu, Y-H., Hu, J-F. (2009). Steroids from the leaves of Chinese Melia azedarach and their cytotoxic effects on human cancer cell lines. Steroids. 74(9): 761-765. doi: 10.1016/j.steroids.2009.04.005
   PubMedGoogle Scholar
• Pan, X., Matsumoto, M., Nishimoto, Y., Ogihara, E., Zhang, J., Ukiya, M., Tokuda, H., Koike, K., Akihisa, M., Akihisa, T. (2014). Cytotoxic and Nitric Oxide Production-Inhibitory Activities of Limonoids and Other Compounds from the Leaves and Bark of Melia azedarach. Chemistry & Biodiversity. 11(8): 1121-1139. doi: 10.1002/cbdv.201400190
   PubMedGoogle Scholar