No association of BMI and body adiposity with cardiometabolic biomarkers among a small sample of reindeer herders of sub-Arctic Finland

References

• WHO. Obesity and overweight. World Heal Organ 2021.
   Google Scholar
• Sassi F. Obesity and the economics of prevention. Cheltenham, United Kingdom: Edward Elgar Publishing. Books. 2010.
   Google Scholar
• Withrow D, Alter DA. The economic burden of obesity worldwide: a systematic review of the direct costs of obesity. Obes Rev. 2011;12(2):131–14.
   PubMed Web of Science ®Google Scholar
• Brown CD, Higgins M, Donato KA, et al. Body mass index and the prevalence of hypertension and dyslipidemia. Obes Res. 2000;8(9):605–619.
   PubMedGoogle Scholar
• Chaput J-P, Doucet É, Tremblay A. Obesity: a disease or a biological adaptation? An update. Obes Rev. 2012;13(8):681–691.
   Web of Science ®Google Scholar
• Fontaine KR, Barofsky I. Obesity and health-related quality of life. Obes Rev. 2001;2(3):71–82.
   Google Scholar
• Guo F, Garvey WT. Cardiometabolic disease risk in metabolically healthy and unhealthy obesity: stability of metabolic health status in adults. Obesity. 2016;24(2):516–525.
   Web of Science ®Google Scholar
• Levy SB, Leonard WR, Tarskaia LA, et al. Lifestyle mediates seasonal changes in metabolic health among the yakut (Sakha) of northeastern siberia. Am J Hum Biol. 2016;28(6):868–878.
   PubMed Web of Science ®Google Scholar
• Frühbeck G, Busetto L, Dicker D, et al. The ABCD of obesity: an EASO position statement on a diagnostic term with clinical and scientific implications. Obes Facts. 2019;12(2):131–136.
   PubMed Web of Science ®Google Scholar
• Kruschitz R, Wallner-Liebmann SJ, Hamlin MJ, et al. Detecting body fat–A weighty problem BMI versus subcutaneous fat patterns in athletes and non-athletes. Romanovsky AA (ed.). PLoS One. 2013;8(8):e72002.
   Web of Science ®Google Scholar
• Wharton S, Lau DCW, Vallis M, et al. Obesity in adults: a clinical practice guideline. CMAJ. 2020;192(31):E875–91.
   PubMed Web of Science ®Google Scholar
• Racette SB, Deusinger SS, Deusinger RH. Obesity: overview of prevalence, etiology, and treatment. Phys Ther Rehabil J. 2003;83:276–288.
   Google Scholar
• Ramachandran A, Snehalatha C. Rising burden of obesity in Asia. J Obes. 2010;2010:1–8.
   Google Scholar
• World Health Organization. The Asia-pacific perspective: redefining obesity and its treatment. Australia; 2000.
   Google Scholar
• WHO Expert Committee. Physical status: the use and interpretation of anthropometry. report of a WHO expert committee - PubMed. World Heal Organ Tech Rep Ser. 1995;854:1–452.
   Web of Science ®Google Scholar
• Bang HO, Dyerberg J. Lipid metabolism and ischemic heart disease in greenland eskimos. In: Harold H. Draper. (eds)., Advances in nutritional research. US: Springer; 1980. p. 1–22.
   Google Scholar
• Bang HO, Dyerberg J, Nielsen AB. Plasma lipid and lipoprotein pattern in Greenlandic West-coast Eskimos. Lancet. 1971;297(7710):1143–1146.
   Web of Science ®Google Scholar
• Kozlov A, Vershubsky G, Kozlova M. Stress under modernization in indigenous populations of Siberia. Int J Circumpolar Health. 2003;62(2):158–166.
   PubMedGoogle Scholar
• Snodgrass JJ, Leonard WR, Sorensen MV, et al. The influence of basal metabolic rate on blood pressure among indigenous Siberians. Am J Phys Anthropol. 2008;137(2):145–155.
   Web of Science ®Google Scholar
• Young T. Obesity, central fat patterning, and their metabolic correlates among the Inuit of the central Canadian Arctic. Hum Biol. 1996;68(2):245–263.
   Web of Science ®Google Scholar
• Young TK, Moffatt MEK, O’Neil JD. Cardiovascular diseases in a Canadian Arctic population. Am J Public Health. 1993;83(6):881–887.
   Web of Science ®Google Scholar
• Young TK, Nikitin YP, Shubnikov EV, et al. Plasma lipids in two indigenous Arctic populations with low risk for cardiovascular diseases. Am J Hum Biol. 1995;7(2):69–87.
   Web of Science ®Google Scholar
• Himms-Hagen J. Lipid metabolism during cold-exposure and during cold-acclimation. Lipids. 1972;7(5):310–323.
   Web of Science ®Google Scholar
• Shephard R, Rode A. The health consequences of “Modernisation”: evidence from circumpolar peoples. Cambridge: Cambridge University Press; 1996.
   Google Scholar
• Snodgrass JJ. Health of indigenous circumpolar populations. Annu Rev Anthropol. 2013;42(1):69–87.
   Web of Science ®Google Scholar
• Snodgrass JJ, Sorensen MV, Tarskaia LA, et al. Adaptive dimensions of health research among indigenous Siberians. Am J Hum Biol. 2007;19(2):1–8.
   Web of Science ®Google Scholar
• Leonard WR, Sorensen MV, Galloway VA, et al. Climatic influences on basal metabolic rates among circumpolar populations. Am J Hum Biol. 2002;14(5):609–620.
   PubMed Web of Science ®Google Scholar
• Snodgrass J, Leonard W, Sorensen M, et al. The emergence of obesity among indigenous Siberians. J Phys Anthropol. 2006;25(1):75–84.
   Google Scholar
• Bjerregaard P, Jørgensen M. Diet, nutrition, and physical activity. In: Young T, Bjerregaard P, editors. Health transitions in arctic populations. Toronto: University of Toronto Press; 2008. p. 192–204.
   Google Scholar
• Cepon TJ, Snodgrass JJ, Leonard WR, et al. Circumpolar adaptation, social change, and the development of autoimmune thyroid disorders among the Yakut (Sakha) of Siberia. Am J Hum Biol. 2011;23(5):703–709.
   Web of Science ®Google Scholar
• Leonard WR, Levy SB, Tarskaia LA, et al. Seasonal variation in basal metabolic rates among the yakut (Sakha) of Northeastern Siberia. Am J Hum Biol. 2014a;26(4):437–445.
   PubMed Web of Science ®Google Scholar
• Prevalence of obesity among adults. World Heal Organ 2020.
   Google Scholar
• Salomaa V, Arstila M, Kaarsalo E, et al. Trends in the incidence of and mortality from coronary heart disease in Finland, 1983–1988. Am J Epidemiol. 1992;136(11):1303–1315.
   PubMed Web of Science ®Google Scholar
• Statistics Finland. Mortality from diseases of the circulatory system decreased further in 2019. 2020.
   Google Scholar
• Tuomilehto J, Rastenyte D, Sivenius J, et al. Ten-Year Trends in Stroke Incidence and Mortality in the FINMONICA stroke study. Stroke. 1996;27(5):825–832.
   Web of Science ®Google Scholar
• Ocobock C, Soppela P, Turunen M, et al. Reindeer herders from subarctic Finland exhibit high total energy expenditure and low energy intake during the autumn herd roundup. Am J Hum Biol 2021 e23676 10.1002/ajhb.23676
   Web of Science ®Google Scholar
• Turunen M, Soppela P, Ocobock C. How reindeer herders cope with harsh winter conditions in northern Finland: insights from an interview study. Arctic. 2021;74(2):188–205.
   Web of Science ®Google Scholar
• Ocobock C, Soppela P, Turunen MT, et al. Elevated resting metabolic rates among female, but not male, reindeer herders from sub-Arctic Finland. Am J Hum Biol. 2020a;32(6):e23432.
   Web of Science ®Google Scholar
• Ocobock C, Soppela P, Turunen MT, et al. Evidence for brown adipose tissue activation among male and female reindeer herders from sub-Arctic Finland. Am Assoc Phys Anthropol. 2020b;171:205.
   Web of Science ®Google Scholar
• Kohonen I, Kuula-Luumi A, Spoof S-K. The ethical principles of research with human participants and ethical review in the human sciences in Finland. Helsinki; 2019.
   Google Scholar
• RHA. Reindeer herders association statistics. 2021.
   Google Scholar
• FMI. Finnish Meteorological Institute. 2021.
   Google Scholar
• Lohman, TG, and Roche, AF, Martorell, R (Eds.) Anthropometric standardization reference manual. Champaign, IL: Human Kinetics Books; 1988.
   Google Scholar
• Sun SS, Chumlea WC, Heymsfield SB, et al. Development of bioelectrical impedance analysis prediction equations for body composition with the use of a multicomponent model for use in epidemiologic surveys. Am J Clin Nutr. 2003;77(2):331–340.
   PubMed Web of Science ®Google Scholar
• Donato LJ, Deobald GR, Wockenfus AM, et al. Comparison of two point of care devices for capillary lipid screening in fasting and postprandial adults. Clin Biochem. 2015;48(3):174–176.
   Web of Science ®Google Scholar
• Raichlen DA, Pontzer H, Harris JA, et al. Physical activity patterns and biomarkers of cardiovascular disease risk in hunter-gatherers. Am J Hum Biol. 2016;29(2):1–13.
   Web of Science ®Google Scholar
• Rustad P, Simonsson P, Felding P, et al. Nordic Reference Interval Project Bio-bank and Database (NOBIDA): a source for future estimation and retrospective evaluation of reference intervals. Scand J Clin Lab Invest. 2004;64(4):431–438.
   PubMed Web of Science ®Google Scholar
• Nichols G, Horberg M, Koebnick C, et al. Cardiometabolic risk factors among 1.3 million adults with overweight or obesity, but not diabetes, in 10 geographically diverse regions of the USA, 2012-2013. Prev Chronic Dis. 2017;14:E22.
   PubMed Web of Science ®Google Scholar
• Gallagher D, Visser M, Sepulveda D, et al. How useful is body mass index for comparison of body fatness across age, sex, and ethnic groups? Am J Epidemiol. 1996;143(3):228–239.
   PubMed Web of Science ®Google Scholar
• Rahman M, Berenson AB. Accuracy of current body mass index obesity classification for white, black, and Hispanic reproductive-age women. Obstet Gynecol. 2010;115(5):982–988.
   PubMed Web of Science ®Google Scholar
• Slattery ML, Ferucci ED, Murtaugh MA, et al. Associations among body mass index, waist circumference, and health indicators in American Indian and Alaska native adults. American Journal of Health Promotion. 2010;24(4):246–254.
   Web of Science ®Google Scholar
• Flegal KM, Kit BK, Orpana H, et al. Association of all-cause mortality with overweight and obesity using standard body mass index categories a systematic review and meta-analysis. J Am Med Assoc. 2013;309(1):71–82.
   PubMed Web of Science ®Google Scholar
• Heymsfield SB, Cefalu WT. Does body mass index adequately convey a patient’s mortality risk? J Am Med Assoc. 2013;309(1):516–525.
   Web of Science ®Google Scholar
• Jiang X, Srinivasan SR, Webber LS, et al. Association of fasting insulin level with serum lipid and lipoprotein levels in children, adolescents, and young adults: the Bogalusa heart study. Arch Intern Med. 1995;155(2):190–196.
   Google Scholar
• Singh GM, Danaei G, Pelizzari PM, et al. The age associations of blood pressure, cholesterol, and glucose: analysis of health examination surveys from international populations. Circulation. 2012;125(18):2204–2211.
   Web of Science ®Google Scholar
• Stoner L, Pontzer H, Barone Gibbs B, et al. Fitness and fatness are both associated with cardiometabolic risk in preadolescents. J Pediatr. 2020;217:39–45.e1.
   Web of Science ®Google Scholar
• Mikkelsen K, Stojanovska L, Polenakovic M, et al. Exercise and mental health. Maturitas. 2017;106:48–56.
   PubMed Web of Science ®Google Scholar
• Duncan GE. The “fit but fat” concept revisited: population-based estimates using NHANES. Int J Behav Nutr Phys Act. 2010;7(1):1–5.
   PubMed Web of Science ®Google Scholar
• Hu G, Tuomilehto J, Silventoinen K, et al. The effects of physical activity and body mass index on cardiovascular, cancer and all-cause mortality among 47 212 middle-aged Finnish men and women. Int J Obes. 2005;29(8):894–902.
   PubMed Web of Science ®Google Scholar
• Weinstein AR, Sesso HD, Lee IM, et al. The joint effects of physical activity and body mass index on coronary heart disease risk in women. Arch Intern Med. 2008;168(8):884–890.
   PubMedGoogle Scholar
• Ortega F, Lee D, Katzmarzyk P, et al. The intriguing metabolically healthy but obese phenotype: cardiovascular prognosis and role of fitness. Eur Heart J. 2013;34(5):389–397.
   PubMed Web of Science ®Google Scholar
• Leonard WR, Levy SB, Tarskaia LA, et al. Seasonal variation in basal metabolic rates among the yakut (Sakha) of Northeastern Siberia. Am J Hum Biol. 2014b;26(4):158–166.
   Web of Science ®Google Scholar
• Durstine JL, Grandjean PW, Davis PG, et al. Blood lipid and lipoprotein adaptations to exercise: a quantitative analysis. Sport Med. 2001;31(15):1509–1517.
   Web of Science ®Google Scholar
• Leon A, Rice T, Mandel S, et al. Blood lipid response to 20 weeks of supervised exercise in a large biracial population: the HERITAGE family study. Metabolism. 2000;49(4):513–520.
   Web of Science ®Google Scholar
• Trejo-Gutierrez J, Fletcher G. Impact of exercise on blood lipids and lipoproteins. J Clin Lipidol. 2007;1(3):175–181.
   Web of Science ®Google Scholar
• Pirinen P, Simola H, Aalto J, et al. Climatological statistics of Finland 1981–2010. Finnish Meteorol Inst Reports. 2012;1:1–96.
   Google Scholar
• Markkula I, Turunen M, Rasmus S. A review of climate change impacts on the ecosystem services in the Saami Homeland in Finland PALOMA View project Gradual changes and abrupt crises-changing operational environment of Finnish reindeer View project A review of climate change impacts on the. Sci Total Environ. 2019;692:1–16.
   Web of Science ®Google Scholar
• Ruosteenoja K, Jylhä K, Kämäräinen M. Climate projections for Finland under the RCP forcing scenarios. Geophysica. 2016;51:17–50.
   Google Scholar
• Froehle AW. Climate variables as predictors of basal metabolic rate: new equations. Am J Hum Biol. 2008;20(5):510–529.
   Web of Science ®Google Scholar
• Galloway V, Leonard WR, Ivakine E. Basal metabolic adaptation of the Evenki reindeer herders of Central Siberia. Am J Hum Biol. 2000;12(1):75–87.
   Web of Science ®Google Scholar
• Rode A, Shephard RJ. Basal metabolic rate of inuit. Am J Hum Biol. 1995;7(6):723–729.
   Web of Science ®Google Scholar
• Snodgrass JJ, Leonard WR, Tarskaia LA, et al. Basal metabolic rate in the Yakut (Sakha) of Siberia. Am J Hum Biol. 2005;17(2):155–172.
   PubMed Web of Science ®Google Scholar
• Levy SB, Klimova TM, Zakharova RN, et al. Brown adipose tissue, energy expenditure, and biomarkers of cardio-metabolic health among the Yakut (Sakha) of northeastern Siberia. Am J Hum Biol. 2018;30(6):e23175.
   Web of Science ®Google Scholar
• van Marken Lichtenbelt WD, Vanhommerig JW, Smulders NM, et al. Cold-activated brown adipose tissue in healthy men. N Engl J Med. 2009;360(15):1500–1508.
   PubMed Web of Science ®Google Scholar
• Steegmann AT. Human cold adaptation: an unfinished agenda. Am J Hum Biol. 2007;19(2):218–227.
   Web of Science ®Google Scholar
• Stocks J, Taylor N, Tipton J, et al. Human Physiological responses to cold exposure. Aviat Sp Environ Med. 2004;75:444–457.
   PubMed Web of Science ®Google Scholar
• Cannon B, Nedergaard J. Yes, even human brown fat is on fire! J Clin Invest. 2012;122(2):486–489.
   Web of Science ®Google Scholar
• Cypess AM, Lehman S, Williams G, et al. Identification and importance of brown adipose tissue in adult humans. N Engl J Med. 2009;360(15):1509–1517.
   PubMed Web of Science ®Google Scholar
• Leonard WR, Levy SB. Contributions of brown adipose tissue to human metabolic adaptation: comparative and evolutionary perspectives - Google Scholar. Am J Phys Anthropol. 2015;156:202.
   Web of Science ®Google Scholar
• Ouellet V, Labbé SM, Blondin DP, et al. Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans. J Clin Invest. 2012;122(2):545–552.
   PubMed Web of Science ®Google Scholar
• Virtanen KA, Lidell ME, Orava J, et al. Functional brown adipose tissue in healthy adults. N Engl J Med. 2009;360(15):1518–1525.
   PubMed Web of Science ®Google Scholar
• van der Lans AAJJ, Vosselman MJ, Hanssen MJW, et al. Supraclavicular skin temperature and BAT activity in lean healthy adults. J Physiol Sci. 2016;66(1):77–83.
   Web of Science ®Google Scholar
• Niclou A, Ocobock C. Weather permitting: increased seasonal efficiency of non-shivering thermogenesis through brown adipose tissue activation in the winter. Am J Hum Biol. (2021): e23716. In Press.
   Google Scholar
• Vallerand AL, Jacobs I. Rates of energy substrates utilization during human cold exposure. Eur J Appl Physiol Occup Physiol. 1989;58(8):873–878.
   Web of Science ®Google Scholar
• Kozlov A, Vershubsky G, Kozlova M. Indigenous peoples of Northern Russia: anthropology and health. Int J Circumpolar Health. 2007;66(sup1):1.
   Google Scholar
• Sorensen MV, Snodgrass JJ, Leonard WR, et al. Lifestyle incongruity, stress and immune function in indigenous Siberians: the health impacts of rapid social and economic change. Am J Phys Anthropol. 1996;138(1):62–69.
   Web of Science ®Google Scholar
• Château-Degat M-L, Dewailly E, Charbonneau G, et al. Obesity risks: towards an emerging Inuit pattern. Int J Circumpolar Health. 2011;70(2):166–177.
   PubMed Web of Science ®Google Scholar
• Harvald B. Third international symposium on circumpolar health. Ugeskr Laeger. 1974;136(44):75–87.
   Google Scholar
• Rode A, Shephard R, Vloshinsky P, et al. Plasma fatty acid profiles of Canadian Inuit and Siberian Ganasan. Arctic Med Res. 1995;54(1):10–20.
   Google Scholar