Health effects of voluntary exposure to cold water – a continuing subject of debate

References

• Wikipedia. Winter swimming. wikipediaorg. 2020 .
   Google Scholar
• The International Ice Swimming Asssociation, Rules and Regulations. 2021. https://internationaliceswimming.com/wp-content/uploads/2021/08/IISA-Swimming-Rules-and-Regulations-Aug-2021.pdf.
   Google Scholar
• International Winter Swimming Association Water Classification. 2019. https://iwsa.world/water-classification/.
   Google Scholar
• Hsaio A. 6 amazing health benefits of cold water swimming. Lifehack. https://www.lifehack.org/288238/6-amazing-health-benefits-cold-water-swimming.
   Google Scholar
• Leppaluoto J, Westerlund T, Huttunen P, et al. Effects of long-term whole-body cold exposures on plasma concentrations of ACTH, beta-endorphin, cortisol, catecholamines and cytokines in healthy females. Scand J Clin Lab Invest. 2008;68(2):145–16.
   PubMed Web of Science ®Google Scholar
• Berbee JF, Boon MR, Khedoe PP, et al. Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development. Nat Commun. 2015;6(1):6356.
   Google Scholar
• Bøkenes L, Alexandersen TE, Østerud B, et al. Physiological and haematological responses to cold exposure in the elderly. Int J Circumpolar Health. 2000;59(3–4):216–221.
   Google Scholar
• Tipton MJ, Collier N, Massey H, et al. Cold water immersion: kill or cure? Exp Physiol. 2017;102(11):1335–1355.
   PubMed Web of Science ®Google Scholar
• Rasmussen L, Mercer J. A comparison of thermal responses in hands and feet of young and elderly subjects in response to local cooling as determined by infared imaging. Thermol Int. 2004;14:71–76.
   Google Scholar
• Stikkbakke, Einar, Mercer, James B. An infrared thermographic and Laser Doppler flowmetric investigation of skin perfusion in the forearm and finger tip following a short period of vascular stasis. Thermology International. 2008 ;18:107–111 .
   Google Scholar
• Nielsen SB, Mercer J. Dynamic thermography in vascular finger disease A methodological study of arteriovenous anastomoses. Thermol Int. 2010;20:93–99.
   Google Scholar
• Lossius K, Eriksen M, Walløe L. Fluctuations in blood flow to acral skin in humans: connection with heart rate and blood pressure variability. J Physiol. 1993;460(1):641–655.
   Google Scholar
• Miland ÅO, Mercer JB. Effect of a short period of abstinence from smoking on rewarming patterns of the hands following local cooling. Eur J Appl Physiol. 2006;98(2):161–168.
   PubMed Web of Science ®Google Scholar
• Hohenauer E, Deliens T, Clarys P, et al. Perfusion of the skin’s microcirculation after cold-water immersion (10°C) and partial-body cryotherapy (−135°C). Skin Res Technol. 2019;25(5):677–682.
   Web of Science ®Google Scholar
• Daanen HA. Finger cold-induced vasodilation: a review. Eur J Appl Physiol. 2003;89(5):411–426.
   PubMed Web of Science ®Google Scholar
• Kenny GP, Denis PM, Proulx CE, et al. The effect of dynamic exercise on resting cold thermoregulatory responses measured during water immersion. Eur J Appl Physiol Occup Physiol. 1999;79(6):495–499.
   Web of Science ®Google Scholar
• Haman F, Blondin DP. Shivering thermogenesis in humans: origin, contribution and metabolic requirement. Temperature (Austin). 2017;4(3):217–226.
   Google Scholar
• Mercer, James B. Hypothermia and Cold Injuries in Man Blatteis, Clark M. Editor. Physiology and pathophysiology of temperature regulation (Singapore.New Jersey.London.Hong Kong: World Scientific). 1998:246–257 .
   Google Scholar
• Norheim AJ, Borud E, Wilsgaard T, et al. Variability in peripheral rewarming after cold stress among 255 healthy Norwegian army conscripts assessed by dynamic infrared thermography. Int J Circumpolar Health. 2018;77(1):1536250.
   PubMed Web of Science ®Google Scholar
• Swift RW. The effects of low environmental temperature upon metabolism: II. the influence of shivering, subcutaneous fat, and skin temperature on heat production. J Nutr. 1932;5(3):227–249.
   Google Scholar
• Martin S, Cooper KE. Factors which affect shivering in man during cold water immersion. Pflügers Archiv. 1981;391(1):81–83.
   Web of Science ®Google Scholar
• Muzik O, Mangner TJ, Leonard WR, et al. Sympathetic innervation of cold-activated brown and white fat in lean young adults. J Nucl Med. 2017;58(5):799–806.
   Web of Science ®Google Scholar
• Gilsanz V, Hu HH, Kajimura S. Relevance of brown adipose tissue in infancy and adolescence. Pediatr Res. 2013;73(1):3–9.
   Web of Science ®Google Scholar
• Muzik O, Mangner TJ, Granneman JG. Assessment of oxidative metabolism in brown fat using PET imaging. Front Endocrinol (Lausanne). 2012;3:15.
   Google Scholar
• Heinonen I, Laukkanen JA. Effects of heat and cold on health, with special reference to Finnish sauna bathing. Am J Physiol Regul Integr Comp Physiol. 2018;314(5):R629–r38.
   PubMed Web of Science ®Google Scholar
• Hayward MG, Keatinge WR. Roles of subcutaneous fat and thermoregulatory reflexes in determining ability to stabilize body temperature in water. J Physiol. 1981;320(1):229–251.
   Google Scholar
• Glickman-Weiss EL, Cheatham C, Caine N, et al. The influence of gender and menstrual phase on thermosensitivity during cold water immersion. Aviat Space Environ Med. 2000;71(7):715–722.
   Google Scholar
• Solianik R, Skurvydas A, Vitkauskienė A, et al. Gender-specific cold responses induce a similar body-cooling rate but different neuroendocrine and immune responses. Cryobiology. 2014;69(1):26–33.
   Web of Science ®Google Scholar
• Reingardiene D. Hypothermia. Medicina (Kaunas). 2003;39(1):90–97.
   Google Scholar
• Potkanowicz ES, Caine-Bish N, Otterstetter R, et al. Age effects on thermal, metabolic, and perceptual responses to acute cold exposure. Aviat Space Environ Med. 2003;74(11):1157–1162.
   PubMedGoogle Scholar
• Castellani JW, Young AJ, Kain JE, et al. Thermoregulatory responses to cold water at different times of day. J Appl Physiol. 1999;87(1):243–246. Bethesda, Md: 1985.
   Web of Science ®Google Scholar
• Krog J, Folkow B, Fox RH, et al. Hand circulation in the cold of Lapps and North Norwegian fishermen. J Appl Physiol. 1960;15(4):654–658.
   PubMed Web of Science ®Google Scholar
• LeBlanc J, Hildes JA, Héroux O. Tolerance of Gaspé fishermen to cold water. J Appl Physiol. 1960;15(6):1031–1034.
   PubMed Web of Science ®Google Scholar
• Nelms JD, Soper DJG. Cold vasodilatation and cold acclimatization in the hands of British fish filleters. J Appl Physiol. 1962;17(3):444–448.
   PubMed Web of Science ®Google Scholar
• Livingstone SD, Grayson J, Reed LD, et al. Effect of a local cold stress on peripheral temperatures of Inuit, Oriental, and Caucasian subjects. Can J Physiol Pharmacol. 1978;56(5):877–881.
   Web of Science ®Google Scholar
• Eglin CM, Costello JT, Tipton MJ, et al. Previous recreational cold exposure does not alter endothelial function or sensory thermal thresholds in the hands or feet. Exp Physiol. 2021;106(1):328–337.
   Web of Science ®Google Scholar
• Smith RM, Hanna JM. Skinfolds and resting heat loss in cold air and water: temperature equivalence. J Appl Physiol. 1975;39(1):93–102.
   PubMed Web of Science ®Google Scholar
• Lindholm P, Lundgren CE. The physiology and pathophysiology of human breath-hold diving. J Appl Physiol. 2009;106(1):284–292.
   PubMed Web of Science ®Google Scholar
• Shattock MJ, Tipton MJ. Autonomic conflict’: a different way to die during cold water immersion? J Physiol. 2012;590(14):3219–3230.
   Web of Science ®Google Scholar
• Mantoni T, Belhage B, Pedersen LM, et al. Reduced cerebral perfusion on sudden immersion in ice water: a possible cause of drowning. Aviat Space Environ Med. 2007;78(4):374–376.
   PubMedGoogle Scholar
• Kralova Lesna I, Rychlikova J, Vavrova L, et al. Could human cold adaptation decrease the risk of cardiovascular disease? J Therm Biol. 2015;52:192–198.
   Web of Science ®Google Scholar
• Broz P, Rajdl D, Racek J, et al. Relationship between cold water swimming and increased cardiac markers: a pilot study. Klin Biochem Metab. 2017;25:27–31.
   Google Scholar
• Stark Matthew , Kerndt, Connor C., Sharma , Sandeep Troponin StatPearls [Internet]. 2022. Updated 2020 Jul 10 https://www.ncbi.nlm.nih.gov/books/NBK507805/. updated 2022 May 8.
   Google Scholar
• Baker P, Leckie T, Harrington D, et al. Exercise-induced cardiac troponin elevation: an update on the evidence, mechanism and implications. Int J Cardiol Heart Vasc. 2019;22:181–186.
   PubMed Web of Science ®Google Scholar
• Zenner RJ, De Decker DE, Clement DL. Blood-pressure response to swimming in ice-cold water. Lancet. 1980;1(8160):120–121.
   Web of Science ®Google Scholar
• Muza SR, Young AJ, Sawka MN, et al. Respiratory and cardiovascular responses to cold stress following repeated cold water immersion. Undersea Biomed Res. 1988;15(3):165–178.
   Google Scholar
• Mantoni T, Rasmussen JH, Belhage B, et al. Voluntary respiratory control and cerebral blood flow velocity upon ice-water immersion. Aviat Space Environ Med. 2008;79(8):765–768.
   Google Scholar
• Tipton MJ, Mekjavic IB, Eglin CM. Permanence of the habituation of the initial responses to cold-water immersion in humans. Eur J Appl Physiol. 2000;83(1):17–21.
   PubMed Web of Science ®Google Scholar
• Chen Y, Ikeda K, Yoneshiro T, et al. Thermal stress induces glycolytic beige fat formation via a myogenic state. Nature. 2019;565(7738):180–185.
   PubMed Web of Science ®Google Scholar
• Abe Y, Fujiwara Y, Takahashi H, et al. Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch. Nat Commun. 2018;9(1):1566.
   Google Scholar
• Søberg S, Löfgren J, Philipsen FE, et al. Altered brown fat thermoregulation and enhanced cold-induced thermogenesis in young, healthy, winter-swimming men. Cell Reports Medicine. 2021;2(10):100408.
   Google Scholar
• Jankovic A, Golic I, Markelic M, et al. Two key temporally distinguishable molecular and cellular components of white adipose tissue browning during cold acclimation. J Physiol. 2015;593(15):3267–3280.
   PubMed Web of Science ®Google Scholar
• Atzmon G, Pollin TI, Crandall J, et al. Adiponectin levels and genotype: a potential regulator of life span in humans. J Gerontol A Biol Sci Med Sci. 2008;63(5):447–453.
   PubMed Web of Science ®Google Scholar
• Imbeault P, Dépault I, Haman F. Cold exposure increases adiponectin levels in men. Metabolism. 2009;58(4):552–559.
   Web of Science ®Google Scholar
• Shephard RJ. Adaptation to exercise in the cold. Sports medicine. (Auckland, NZ). 1985;2(1):59–71.
   PubMed Web of Science ®Google Scholar
• Janský L, Janáková H, Uličný B, et al. Changes in thermal homeostasis in humans due to repeated cold water immersions. Pflügers Archiv. 1996;432(3):368–372.
   PubMed Web of Science ®Google Scholar
• Smolander J, Mikkelsson M, Oksa J, et al. Thermal sensation and comfort in women exposed repeatedly to whole-body cryotherapy and winter swimming in ice-cold water. Physiol Behav. 2004;82(4):691–695.
   PubMed Web of Science ®Google Scholar
• Naidu M, Sachdeva U. Effect of local cooling on skin temperature and blood flow of men in Antarctica. Int J Biometeorol. 1993;37(4):218–221.
   Web of Science ®Google Scholar
• Tipton MJ, Franks GM, Meneilly GS, et al. Substrate utilisation during exercise and shivering. Eur J Appl Physiol Occup Physiol. 1997;76(1):103–108.
   Web of Science ®Google Scholar
• Tipton MJ, Wakabayashi H, Barwood MJ, et al. Habituation of the metabolic and ventilatory responses to cold-water immersion in humans. J Therm Biol. 2013;38(1):24–31.
   PubMed Web of Science ®Google Scholar
• Kuroshima A. Regulation of thermoregulatory thermogenesis. [Hokkaido Igaku Zasshi] the Hokkaido Journal of Medical Science. 1995;70(1):1–8.
   Google Scholar
• Vybíral S, Lesná I, Jansky L, et al. Thermoregulation in winter swimmers and physiological significance of human catecholamine thermogenesis. Exp Physiol. 2000;85(3):321–326.
   Web of Science ®Google Scholar
• Janský L. Physiologic basis of human adaptation to cold. Ceskoslovenska Fysiologie. 2003;52(3):107–117.
   Google Scholar
• Elkington EJ. Finger blood flow in Antarctica. J Physiol. 1968;199(1):1–10.
   Web of Science ®Google Scholar
• Geurts CL, Sleivert GG, Cheung SS. Central and peripheral factors in thermal, neuromuscular, and perceptual adaptation of the hand to repeated cold exposures. Appl Physiol Nutr Metab = Physiologie Appliquee, Nutrition Et Metabolisme. 2006;31(2):110–117.
   PubMed Web of Science ®Google Scholar
• Park J, Kim S, Kim DH, et al. Whole-body cold tolerance in older Korean female divers “haenyeo” during cold air exposure: effects of repetitive cold exposure and aging. Int J Biometeorol. 2018;62(4):543–551.
   Web of Science ®Google Scholar
• Glickman EI, Caine-Bish N. Changes in body temperature and basal metabolic rate of the ama—A commentary. Wilderness Environ Med. 2003;14(3):191–192.
   Web of Science ®Google Scholar
• Park YS, Rennie DW, Lee IS, et al. Time course of deacclimatization to cold water immersion in Korean women divers. J Appl Physiol Respir Environ Exerc Physiol. 1983;54(6):1708–1716.
   Web of Science ®Google Scholar
• Lundgren P, Henriksson O, Kuklane K, et al. Validity and reliability of the cold discomfort scale: a subjective judgement scale for the assessment of patient thermal state in a cold environment. J Clin Monit Comput. 2014;28(3):287–291.
   Web of Science ®Google Scholar
• Huttunen P, Rintamäki H, Hirvonen J. Effect of regular winter swimming on the activity of the sympathoadrenal system before and after a single cold water immersion. Int J Circumpolar Health. 2001;60(3):400–406.
   Google Scholar
• Kauppinen K, Pajari-Backas M, Volin P, et al. Some endocrine responses to sauna, shower and ice water immersion. Arct Med Res. 1989;48(3):131–139.
   Google Scholar
• Smolander J, Leppäluoto J, Westerlund T, et al. Effects of repeated whole-body cold exposures on serum concentrations of growth hormone, thyrotropin, prolactin and thyroid hormones in healthy women. Cryobiology. 2009;58(3):275–278.
   Web of Science ®Google Scholar
• Hermanussen M, Jensen F, Hirsch N, et al. Acute and chronic effects of winter swimming on LH, FSH, prolactin, growth hormone, TSH, cortisol, serum glucose and insulin. Arct Med Res. 1995;54(1):45–51.
   Google Scholar
• Gibas-Dorna M, Chęcińska Z, Korek E, et al. Cold water swimming beneficially modulates insulin sensitivity in middle-aged individuals. J Aging Phys Act. 2016;24(4):547–554.
   Web of Science ®Google Scholar
• Gibas-Dorna M, Checinska Z, Korek E, et al. Variations in leptin and insulin levels within one swimming season in non-obese female cold water swimmers. Scand J Clin Lab Invest. 2016;76(6):486–491.
   PubMed Web of Science ®Google Scholar
• Zeyl A, Stocks JM, Taylor NA, et al. Interactions between temperature and human leptin physiology in vivo and in vitro. Eur J Appl Physiol. 2004;92(4–5):571–578.
   Web of Science ®Google Scholar
• Kovaničová Z, Kurdiová T, Baláž M, et al. Cold exposure distinctively modulates parathyroid and thyroid hormones in cold-acclimatized and non-acclimatized humans. Endocrinology. 2020;161(7). DOI:10.1210/endocr/bqaa051.
   Web of Science ®Google Scholar
• Peretti D, Bastide A, Radford H, et al. RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration. Nature. 2015;518(7538):236–239.
   PubMed Web of Science ®Google Scholar
• Yang CC, Wang J, Chen SC, et al. Enhanced functional recovery from sciatic nerve crush injury through a combined treatment of cold-water swimming and mesenchymal stem cell transplantation. Neurol Res. 2015;37(9):816–826.
   PubMed Web of Science ®Google Scholar
• Arai Y, Martin-Ruiz CM, Takayama M, et al. Inflammation, but not telomere length, predicts successful ageing at extreme old age: a longitudinal study of semi-supercentenarians. EBioMedicine. 2015;2(10):1549–1558.
   Web of Science ®Google Scholar
• Janský L, Pospísilová D, Honzová S, et al. Immune system of cold-exposed and cold-adapted humans. Eur J Appl Physiol Occup Physiol. 1996;72(5–6):445–450.
   Web of Science ®Google Scholar
• Dugué B, Leppänen E. Adaptation related to cytokines in man: effects of regular swimming in ice-cold water. Clin Physioly (Oxford, England). 2000;20(2):114–121.
   PubMedGoogle Scholar
• Pawłowska M, Mila-Kierzenkowska C, Boraczyński T, et al. The effect of submaximal exercise followed by short-term cold-water immersion on the inflammatory state in healthy recreational athletes: a cross-over study. J Clin Med. 2021;10(18):4239.
   Web of Science ®Google Scholar
• Kessler B, Rinchai D, Kewcharoenwong C, et al. Interleukin 10 inhibits pro-inflammatory cytokine responses and killing of Burkholderia pseudomallei. Sci Rep. 2017;7(1):42791.
   PubMedGoogle Scholar
• Siems WG, van Kuijk Fj, Maass R, et al. Uric acid and glutathione levels during short-term whole body cold exposure. Free Radic Biol Med. 1994;16(3):299–305.
   Web of Science ®Google Scholar
• Mila-Kierzenkowska C, Woźniak A, Boraczyński T, et al. Thermal stress and oxidant–antioxidant balance in experienced and novice winter swimmers. J Therm Biol. 2012;37(8):595–601.
   Web of Science ®Google Scholar
• Lubkowska A, Dołęgowska B, Szyguła Z, et al. Winter-swimming as a building-up body resistance factor inducing adaptive changes in the oxidant/antioxidant status. Scand J Clin Lab Invest. 2013;73(4):315–325.
   PubMed Web of Science ®Google Scholar
• Siems WG, Brenke R, Sommerburg O, et al. Improved antioxidative protection in winter swimmers. Qjm. 1999;92(4):193–198.
   Web of Science ®Google Scholar
• Collier N, Massey HC, Lomax M, et al. Cold water swimming and upper respiratory tract infections. Extrem Physiol Med. 2015;4(1):A36.
   Google Scholar
• Kormanovski A, Ibarra F, Padilla E, et al. Resistance to respiratory illness and antibody response in open water swimmers during training and long distance swims. Int J Med Med Sci. 2010;2:80–87.
   Google Scholar
• Malhi, Gin S., Mann, J. John, et al. Depression. Lancet. 2010 392 2299–2312. doi:10.1016/S0140-6736(18)31948-2.
   Google Scholar
• Shevchuk NA. Adapted cold shower as a potential treatment for depression. Med Hypotheses. 2008;70(5):995–1001.
   PubMed Web of Science ®Google Scholar
• van Tulleken C, Tipton M, Massey H, et al. Open water swimming as a treatment for major depressive disorder. BMJ Case Rep. 2018;2018. DOI:10.1136/bcr-2018-225007
   Google Scholar
• Lindeman S, Hirvonen J, Joukamaa M. Neurotic psychopathology and alexithymia among winter swimmers and controls–a prospective study. Int J Circumpolar Health. 2002;61(2):123–130.
   PubMedGoogle Scholar
• Huttunen P, Kokko L, Ylijukuri V. Winter swimming improves general well-being. Int J Circumpolar Health. 2004;63(2):140–144.
   PubMedGoogle Scholar
• Leeder JDC, Godfrey M, Gibbon D, et al. Cold water immersion improves recovery of sprint speed following a simulated tournament. Eur J Sport Sci. 2019;19(9):1166–1174.
   PubMed Web of Science ®Google Scholar
• Mawhinney C, Jones H, Joo CH, et al. Influence of cold-water immersion on limb and cutaneous blood flow after exercise. Med Sci Sports Exerc. 2013;45(12):2277–2285.
   PubMed Web of Science ®Google Scholar
• Ihsan M, Watson G, Lipski M, et al. Influence of postexercise cooling on muscle oxygenation and blood volume changes. Med Sci Sports Exerc. 2013;45(5):876–882.
   PubMed Web of Science ®Google Scholar
• Knechtle B, Waśkiewicz Z, Sousa CV, et al. Cold water swimming-benefits and risks: a narrative review. Int J Environ Res Public Health. 2020;17(23):8984.
   Web of Science ®Google Scholar
• Keatinge WR, Evans M. The respiratory and cardiovascular response to immersion in cold and warm water. Q J Exp Physiol. 1961;46(1):83–94.
   Google Scholar
• Mekjavić IB, La Prairie A, Burke W, et al. Respiratory drive during sudden cold water immersion. Respiration Physiol. 1987;70(1):121–130.
   Google Scholar
• Tipton MJ. The initial responses to cold-water immersion in man. Clin sci. 1989;77(6):581–588.
   PubMed Web of Science ®Google Scholar
• Radford Imogen, Harper, Mark, Rew, Kate. Understanding hypothermia. The Outdoor Swimming Society https://www.outdoorswimmingsociety.com/understanding-hypothermia/.
   Google Scholar
• Heil K, Thomas R, Robertson G, et al. Freezing and non-freezing cold weather injuries: a systematic review. Br Med Bull. 2016;117(1):79–93.
   PubMed Web of Science ®Google Scholar