Markers of oxidative stress and inflammation increase in the lung and liver of partially irradiated rats

References

• Pospíšil P, Prasad A, Rác M. Mechanism of the formation of electronically excited species by oxidative metabolic processes: role of reactive oxygen species. Biomolecules. 2019;9(7):258. doi: 10.3390/biom9070258
   PubMed Web of Science ®Google Scholar
• Georgiou CD, Zisimopoulos D, Kalaitzopoulou E, et al. Radiation-driven formation of reactive oxygen species in oxychlorine-containing mars surface analogues. Astrobiology. 2017;17(4):319–336. doi: 10.1089/ast.2016.1539
   PubMed Web of Science ®Google Scholar
• Abdelrazzak AB, O’Neill P, Hill MA. Influence of ionizing radiation and cell density on the kinetics of autocrine destruction and intercellular induction of apoptosis in precancerous cells. Sci Rep. 2022;12(1):1–12. doi: 10.1038/s41598-022-11253-1
   PubMed Web of Science ®Google Scholar
• Abdelrazzak AB, O’Neill P, Hill MA. Intercellular induction of apoptosis signalling pathways. Radiat Prot Dosim. 2011;143(2–4):289–293. doi: 10.1093/rpd/ncq387
   PubMed Web of Science ®Google Scholar
• Abdelrazzak AB, Pottgießer SJ, Hill MA, et al. Enhancement of peroxidase release from non-malignant and malignant cells through low-dose Irradiation with different radiation quality. Radiat Res. 2016;185(2):199–213. doi: 10.1667/RR14245.1
   PubMed Web of Science ®Google Scholar
• Abdelrazzak AB, Stevens DL, Bauer G, et al. The role of radiation quality in the stimulation of Intercellular Induction of apoptosis in transformed cells at very low doses. Radiat Res. 2011;176(3):346–355. doi: 10.1667/RR2509.1
   PubMed Web of Science ®Google Scholar
• Martin KR, Barrett JC. Reactive oxygen species as double-edged swords in cellular processes: low-dose cell signaling versus high-dose toxicity. Hum Exp Toxicol. 2002;21(2):71–75. doi: 10.1191/0960327102ht213oa
   PubMed Web of Science ®Google Scholar
• Shimura T, Kunugita N. Mitochondrial reactive oxygen species-mediated genomic instability in low-dose irradiated human cells through nuclear retention of cyclin D1. Cell Cycle. 2016;15(11):1410–1414. doi: 10.1080/15384101.2016.1170271
   PubMed Web of Science ®Google Scholar
• Temme J, Bauer G. Low-dose gamma irradiation enhances superoxide anion production by nonirradiated cells through TGF-β1-dependent bystander signaling. Radiat Res. 2013;179(4):422–432. doi: 10.1667/RR3161.2
   PubMed Web of Science ®Google Scholar
• Chittezhath M, Kuttan G. Radioprotective activity of naturally occurring organosulfur compounds. Tumori J. 2006;92(2):163–169. doi: 10.1177/030089160609200213
   PubMed Web of Science ®Google Scholar
• Kohen R, Nyska A. Invited review: oxidation of biological systems: oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification. Toxicol Pathol. 2002;30(6):620–650. doi: 10.1080/01926230290166724
   PubMed Web of Science ®Google Scholar
• Dong S, Lyu X, Yuan S, et al. Oxidative stress: a critical hint in ionizing radiation induced pyroptosis. Radiat Med Prot. 2020;1(4):179–185. doi: 10.1016/j.radmp.2020.10.001
   Google Scholar
• Kim W, Lee S, Seo D, et al. Cellular stress responses in radiotherapy. Cells. 2019;8(9):1105. doi: 10.3390/cells8091105
   PubMed Web of Science ®Google Scholar
• Azzam EI, Jay-Gerin J-P, Pain D. Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury. Cancer Lett. 2012;327(1–2):48–60. doi: 10.1016/j.canlet.2011.12.012
   PubMed Web of Science ®Google Scholar
• Abouelsayed A, Hezma A, El-Bahy GS, et al. Modification of protein secondary structure as an indicator of radiation-induced abscopal effect: a spectroscopic investigation. Spectrochim Acta A Mol Biomol Spectrosc. 2023;287:122093. doi: 10.1016/j.saa.2022.122093
   PubMed Web of Science ®Google Scholar
• Fernandez-Palomo C, Schültke E, Bräuer-Krisch E, et al. Investigation of abscopal and bystander effects in immunocompromised mice after exposure to pencilbeam and microbeam synchrotron radiation. Health Phys. 2016;111(2):149–159. doi: 10.1097/HP.0000000000000525
   PubMed Web of Science ®Google Scholar
• Munro AJ. Bystander effects and their implications for clinical radiotherapy. J Radiol Prot. 2009;29(2A):A133–A142. doi: 10.1088/0952-4746/29/2A/S09
   PubMed Web of Science ®Google Scholar
• Mohye El-Din AA, Abdelrazzak AB, Ahmed MT, et al. Radiation induced bystander effects in the spleen of cranially-irradiated rats. British J Radiol. 2017;90(1080):20170278. doi: 10.1259/bjr.20170278
   PubMed Web of Science ®Google Scholar
• Abouelsayed A, El-Bahy GS, Abdelrazzak AB. FTIR spectroscopic investigations of protein conformation provide clues of radioadaptation in the kidney of low-dose irradiated rats. J Mol Struct. 2024;1295(part 1):136643. doi: 10.1016/j.molstruc.2023.136643
   Google Scholar
• Abdelrazzak AB, Hezma A, El-Bahy GS. ATR-FTIR spectroscopy probing of structural alterations in the cellular membrane of abscopal liver cells. Biochimi Biophys Acta (BBA) Biomembr. 2021;1863(11):183726. doi: 10.1016/j.bbamem.2021.183726
   PubMed Web of Science ®Google Scholar
• Marin A, Martin M, Linan O, et al. Bystander effects and radiotherapy. Rep Pract Oncol Radiother: J Greatpoland Cancer Center Poznan And Polish Soci Radiat Oncol. 2015;20(1):12–21. doi: 10.1016/j.rpor.2014.08.004
   PubMedGoogle Scholar
• Little JB, Azzam EI, de Toledo SM, et al. Bystander effects: intercellular transmission of radiation damage signals. Radiat Prot Dosimetry. 2002;99(1–4):159–162. doi: 10.1093/oxfordjournals.rpd.a006751
   PubMed Web of Science ®Google Scholar
• Hall EJ, Giaccia AJ. Radiobiology for the Radiologist. Lippincott Williams & Wilkins Philadelphia, USA. 2006.
   Google Scholar
• Demaria S, Ng B, Devitt ML, et al. Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated. Int J Radiat Oncol* Biol* Phys. 2004;58(3):862–870. doi: 10.1016/j.ijrobp.2003.09.012
   PubMed Web of Science ®Google Scholar
• Camphausen K, Moses MA, Ménard C, et al. Radiation abscopal antitumor effect is mediated through p53. Cancer Res. 2003;63(8):1990–1993.
   PubMed Web of Science ®Google Scholar
• Koturbash I, Loree J, Kutanzi K, et al. In vivo bystander effect: cranial X-irradiation leads to elevated DNA damage, altered cellular proliferation and apoptosis, and increased p53 levels in shielded spleen. Int J Radiat Oncol* Biolo* Phys. 2008;70(2):554–562. doi: 10.1016/j.ijrobp.2007.09.039
   PubMed Web of Science ®Google Scholar
• Koturbash I, Rugo R, Hendricks C, et al. Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo. Oncogene. 2006;25(31):4267. doi: 10.1038/sj.onc.1209467
   PubMed Web of Science ®Google Scholar
• Pouget J-P, Georgakilas AG, Ravanat J-L. Targeted and off-target (bystander and abscopal) effects of radiation therapy: redox mechanisms and risk/benefit analysis. Antioxid Redox Signaling. 2018;29(15):1447–1487. doi: 10.1089/ars.2017.7267
   PubMed Web of Science ®Google Scholar
• Avti P, Pathak C, Kumar S, et al. Low dose gamma-irradiation differentially modulates antioxidant defense in liver and lungs of Balb/c mice. Int J Radiat Biol. 2005;81(12):901–910. doi: 10.1080/09553000600567996
   PubMed Web of Science ®Google Scholar
• Kang T-C. Nuclear factor-erythroid 2-related factor 2 (Nrf2) and mitochondrial dynamics/mitophagy in neurological diseases. Antioxidants. 2020;9(7):617. doi: 10.3390/antiox9070617
   Web of Science ®Google Scholar
• Abdelrazzak AB, El-Missiry MA, Ahmed MT, et al. Effect of low-dose X-rays on the liver of whole-body irradiated rats. Int J Radiat Biol. 2019;95(3):264–273. doi: 10.1080/09553002.2019.1554925
   PubMed Web of Science ®Google Scholar
• Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72(1–2):248–254. doi: 10.1016/0003-2697(76)90527-3
   PubMed Web of Science ®Google Scholar
• Gaschler MM, Stockwell BR. Lipid peroxidation in cell death. Biochem Biophys Res Commun. 2017;482(3):419–425. doi: 10.1016/j.bbrc.2016.10.086
   PubMed Web of Science ®Google Scholar
• Esterbauer H, Eckl P, Ortner A. Possible mutagens derived from lipids and lipid precursors. Mutation Res/Rev Genet Toxicol. 1990;238(3):223–233. doi: 10.1016/0165-1110(90)90014-3
   PubMedGoogle Scholar
• Marnett LJ. Lipid peroxidation—DNA damage by malondialdehyde. Mutat Res. 1999;424(1–2):83–95. doi: 10.1016/S0027-5107(99)00010-X
   PubMed Web of Science ®Google Scholar
• Zhang W, He Q, Chan L, et al. Involvement of caspases in 4-hydroxy-alkenal–induced apoptosis in human leukemic cells. Free Radic Biol Med. 2001;30(6):699–706. doi: 10.1016/S0891-5849(01)00465-8
   PubMed Web of Science ®Google Scholar
• Abadi SHMH, Shirazi A, Alizadeh AM, et al. The effect of melatonin on superoxide dismutase and glutathione peroxidase activity, and malondialdehyde levels in the targeted and the non-targeted lung and heart tissues after irradiation in xenograft mice colon cancer. Curr Mol Pharmacol. 2018;11(4):326–335. doi: 10.2174/1874467211666180830150154
   PubMed Web of Science ®Google Scholar
• Rashed ER, Abdel-Rafei MK, Thabet NM. Roles of simvastatin and sildenafil in modulation of cranial irradiation-induced bystander multiple organs injury in rats. Inflammation. 2021;44(6):2554–2579. doi: 10.1007/s10753-021-01524-w
   PubMed Web of Science ®Google Scholar
• Greenberger JS. Radioprotection. Vivo. 2009;23(2):323–336.
   PubMed Web of Science ®Google Scholar
• Schaue D, Micewicz ED, Ratikan JA, et al. Radiation and inflammation. Radiat Oncol J. 2015;25(1):4–10.
   Google Scholar
• Verma V, Lin SH. Implications of the bystander and abscopal effects of radiation therapy. Clin Cancer Res. 2016;22(19):4763–4765. doi: 10.1158/1078-0432.CCR-16-1512
   PubMed Web of Science ®Google Scholar
• Barcellos-Hoff MH, Dix TA. Redox-mediated activation of latent transforming growth factor-beta 1. Mol Endocrinol. 1996;10(9):1077–1083. doi: 10.1210/mend.10.9.8885242
   PubMedGoogle Scholar
• Ehrhart E, Segarini P, Tsang MLS, et al. Latent transforming growth factor β1 activation in situ: quantitative and functional evidence after low‐dose γ‐irradiation 1. FASEB J. 1997;11(12):991–1002. doi: 10.1096/fasebj.11.12.9337152
   PubMed Web of Science ®Google Scholar
• Assoian RK, Fleurdelys BE, Stevenson HC, et al. Expression and secretion of type beta transforming growth factor by activated human macrophages. Proc Natl Acad Sci, USA. 1987;84(17):6020–6024. doi: 10.1073/pnas.84.17.6020
   PubMed Web of Science ®Google Scholar
• Grotendorst GR, Smale G, Pencev D. Production of transforming growth factor beta by human peripheral blood monocytes and neutrophils. J Cell Physiol. 1989;140(2):396–402. doi: 10.1002/jcp.1041400226
   PubMed Web of Science ®Google Scholar
• Iyer R, Lehnert BE. Effects of ionizing radiation in targeted and nontargeted cells. Arch Biochem Biophys. 2000;376(1):14–25. doi: 10.1006/abbi.1999.1684
   PubMed Web of Science ®Google Scholar
• Gow M, Seymour C, Ryan L, et al. Induction of bystander response in human glioma cells using high-energy electrons: a role for TGF-β1. Radiat Res. 2010;173(6):769–778. doi: 10.1667/RR1895.1
   PubMed Web of Science ®Google Scholar
• Shao C, Folkard M, Prise KM. Role of TGF-beta 1 and nitric oxide in the bystander response of irradiated glioma cells. Oncogene. 2008;27(4):434–440. doi: 10.1038/sj.onc.1210653
   PubMed Web of Science ®Google Scholar
• Jiang Y, Chen X, Tian W, et al. The role of TGF-β1–miR-21–ROS pathway in bystander responses induced by irradiated non-small-cell lung cancer cells. Br J Cancer. 2014;111(4):772–780. doi: 10.1038/bjc.2014.368
   PubMed Web of Science ®Google Scholar
• Cabrero A, Alegret M, Sánchez RM, et al. Increased reactive oxygen species production down-regulates peroxisome proliferator-activated α pathway in C2C12 skeletal muscle cells. J Biol Chem. 2002;277(12):10100–10107. doi: 10.1074/jbc.M110321200
   PubMed Web of Science ®Google Scholar
• Mukherjee S, Dutta A, Chakraborty A. The cross-talk between Bax, Bcl2, caspases, and DNA damage in bystander HepG2 cells is regulated by γ-radiation dose and time of conditioned media transfer. Apoptosis. 2022;27(3–4):184–205. doi: 10.1007/s10495-022-01713-4
   PubMed Web of Science ®Google Scholar
• Walsh JG, Cullen SP, Sheridan C, et al. Executioner caspase-3 and caspase-7 are functionally distinct proteases. Proc Natl Acad Sci, USA. 2008;105(35):12815–12819. doi: 10.1073/pnas.0707715105
   PubMed Web of Science ®Google Scholar
• Porter AG, Jänicke RU. Emerging roles of caspase-3 in apoptosis. Cell Death Diff. 1999;6(2):99–104. doi: 10.1038/sj.cdd.4400476
   PubMed Web of Science ®Google Scholar