Effects of some flavor enhancer food additives on expression of cancer-related genes in MCF-7 and MCF-12A cells

References

• Aaron, G., Bart, A. G., & Scott, E. E. (2018). Structures of human cytochrome P450 CYP1A1 with bergamottin and erlotinib reveal active-site modifications for binding of diverse ligands. Journal of Biological Chemistry, 293(50), 19201–11. https://doi.org/10.1074/jbc.RA118.005588
   PubMed Web of Science ®Google Scholar
• Abu Zeid, E. H., El Sharkawy, N. I., Moustafa, G. G., Anwer, A. M., & Al Nady, A. G. (2021). The palliative effect of camel milk on hepatic CYP1A1 gene expression and DNA damage induced by fenpropathrin oral intoxication in male rats. Ecotoxicology and Environmental Safety, 207, 111296. https://doi.org/10.1016/j.ecoenv.2020.111296
   PubMed Web of Science ®Google Scholar
• Adeyemo, O. A., & Farinmade, A. E. (2013). Genotoxic and cytotoxic effects of food flavor enhancer, Monosodium Glutamate (MSG) using allium cepa assay. African Journal of Biotechnology, 12(13), 1459–1466. https://doi.org/10.5897/AJB12.2927
   Google Scholar
• Akin, A., & Sumer, S. (1991). The mutagenic effects of sodium nitrite and monosodium glutamate used as food additives demonstrated by the salmonella microsome test system. Mikrobiyoloji Bülteni, 25(1), 94–107. https://pubmed.ncbi.nlm.nih.gov/1881365
   PubMedGoogle Scholar
• Alakananda Basu, A. (2022). The interplay between apoptosis and cellular senescence: BCL-2 family proteins as targets for cancer therapy. Pharmacology & Therapeutics, 230, 107943. https://doi.org/10.1016/j.pharmthera.2021.107943
   PubMed Web of Science ®Google Scholar
• Altug, T. (2009). Gıda Katkı Maddeleri. In T. Altuğ (Ed.), Food additives (3rd ed., pp. 1–16). Kan Yılmaz Publishing.
   Google Scholar
• Amin, L., Azad, M. A. K., & Samian, A. L. (2013). Factor influencing risk perception of food additives. Journal of Food, Agriculture and Environment, 11(2), 66–72. https://doi.org/10.1234/4.2013.4192
   Google Scholar
• Androutsopoulos, V. P., Tsatsakis, A. M., & Spandidos, D. A. (2009). Cytochrome P450 CYP1A1: Wider roles in cancer progression and prevention. BMC Cancer, 9(1), 187. https://doi.org/10.1186/1471-2407-9-187
   PubMed Web of Science ®Google Scholar
• Annick, D. B., Villevoye, J., Nijmeijer, S. M., Van den Berg, M., & Majorie, B. M. (2019). Anti-tumor properties of methoxylated analogues of resveratrol in malignant MCF-7 but not in non-tumorigenic MCF-10A mammary epithelial cell lines. Toxicology, 422, 35–43. https://doi.org/10.1016/j.tox.2019.04.009
   PubMed Web of Science ®Google Scholar
• Appaiah, K. M. (2010). Monosodium glutamate in foods and its biological effects. In C. Boisrobert, S. Oh, A. Stjepanovic, & H. Lelieveld Eds., Ensuring global food safety (pp. 217–226). https://doi.org/10.1016/B978-0-12-374845-4.00013-8
   Google Scholar
• Ataseven, N., Yuzbasioglu, D., Keskin, A. Ç., & Unal, F. (2016). Genotoxicity of monosodium glutamate. Food and Chemical Toxicology, 91, 8–18. https://doi.org/10.1016/j.fct.2016.02.021
   PubMed Web of Science ®Google Scholar
• Avuloglu-Yilmaz, E., Bolukbasi, E., & Yildirim, T. (2020). Investigation of the cytotoxic effects of three different food additives using MTT assay. International Eurasian Conference on Biotechnology and Biochemistry, December 16-18, 2020, Ankara, Turkey.
   Google Scholar
• Avuloglu-Yilmaz, E., Yuzbasioglu, D., & Unal, F. (2020). In vitro genotoxicity assessment of monopotassium glutamate and magnesium diglutamate. Toxicology in Vitro, 65, 104780. https://doi.org/10.1016/j.tiv.2020.104780
   PubMed Web of Science ®Google Scholar
• Basoglu, F. (2016). Fundamentals of food quality control and food safety management systems (3rd ed.). Dora Publishing.
   Google Scholar
• Bolukbasi, E. (2021). Expression analysis of some stress-related genes induced by cadmium on tomato (S. lycopersicum L.) plants. Hittite Journal of Science and Engineering, 8(4), 339–345. https://doi.org/10.17350/HJSE19030000247
   Google Scholar
• Bolukbasi, E. (2022). Influence of boron treatments on fatty acid desaturase metabolism in different safflower cultivars. Soil and Environment, 68(10), 479–486. https://doi.org/10.17221/228/2022-PSE
   Web of Science ®Google Scholar
• Buyuk, I., Bolukbasi, E., & Aras, E. S. (2016). Expression of CtFAD2 gene for early selection in safflower oleic linoleic oil content. Journal of Animal and Plant Sciences, 26(5), 1383–1388. https://www.thejaps.org.pk/docs/v-26-05/27.pdf
   Web of Science ®Google Scholar
• Canitezer, T., & Topaktas, M. (2012). Effects of monosodium glutamate (MSG) on sister chromatid exchange in human peripheral lymphocytes. Cukurova University Journal of the Faculty of Engineering, 28(2), 76–85. https://fbe.cu.edu.tr/storage/fbeyedek/makaleler/cild28sayi2-76-85.html
   Google Scholar
• Cartus, A., & Schrenk, D. (2017). Current methods in risk assessment of genotoxic chemicals. Food and Chemical Toxicology, 106, 574–582. https://doi.org/10.1016/j.fct.2016.09.012
   PubMed Web of Science ®Google Scholar
• Colin, D., Godwin, O. M., Bates, S. R. J., George, S., Laszlo, G. S., & Walter, R. B. (2020). Anti-apoptotic BCL-2 family proteins confer resistance to calicheamicin-based antibody-drug conjugate therapy of acute leukemia. Leukemia & Lymphoma, 61(12), 2990–2994. https://doi.org/10.1080/10428194.2020.1786553
   PubMed Web of Science ®Google Scholar
• Erden Calişir, Z., & Caliskan, D. (2003). Food additives and effects on the human health. Journal of Faculty of Pharmacy of Ankara University, 32(3), 207–206. https://doi.org/10.1501/Eczfak_0000000411
   Google Scholar
• Fleming, K., Thorson, E., & Zhang, Y. (2006). Going beyond exposure to local news media: An information-processing examination of public perceptions of food safety. Journal of Health Communication, 11(8), 789–806. https://doi.org/10.1080/10810730600959705
   PubMed Web of Science ®Google Scholar
• Ghasemi, M., Turnbull, T., Sebastian, S., & Kempson, I. (2021). The MTT assay: Utility, limitations, pitfalls, and interpretation in bulk and single-cell analysis. International Journal of Molecular Sciences, 22(23), 12827. https://doi.org/10.3390/ijms222312827
   PubMed Web of Science ®Google Scholar
• Hwang, Y., & Lee, M. (2012, May). Comparison of the AdvanSure human papillomavirus screening real-time PCR, the Abbott RealTime high risk human papillomavirus test, and the hybrid capture human papillomavirus DNA test for the detection of human papillomavirus. Annals of Laboratory Medicine, 32(3), 201–205. https://doi.org/10.3343/alm.2012.32.3.201
   PubMed Web of Science ®Google Scholar
• Jones, J. E., & Nebert, D. W. (1989). Transcriptional start site in the mouse CYP1A1 (cytochrome P1450) gene. DNA (Mary Ann Liebert, Inc), 8(7), 527–534. https://doi.org/10.1089/dna.1.1989.8.527
   PubMedGoogle Scholar
• Kassab, R. B., Theyab, A., Al-Ghamdy, A. O., Algahtani, M., Mufti, A. H., Alsharif, K. F., Abdella, E. M., Habotta, O. A., Omran, M. M., Lokman, M. S., Bauomy, A. A., Albrakati, A., Baty, R. S., Hassan, K. E., Alshiekheid, M. A., Abdel Moneim, A. E., & Elmasry, H. A. (2022). Protocatechuic acid abrogates oxidative insults, inflammation, and apoptosis in liver and kidney associated with monosodium glutamate intoxication in rats. Environmental Science and Pollution Research, 29(8), 12208–12221. https://doi.org/10.1007/s11356-021-16578-4
   PubMed Web of Science ®Google Scholar
• Khatab, H. A., & Elhaddad, N. S. (2015). Evaluation of mutagenic effects of monosodium glutamate using allium cepa and antimutagenic action of origanum majorana L. and ruta chalepensis medical plants. British Biotechnology Journal, 8(1), 1–11. https://doi.org/10.9734/BBJ/2015/17695
   Google Scholar
• Knight, T., Luedtke, D., Edwards, H., Taub, J. W., & Ge, Y. (2019). A delicate balance-the BCL-2 family and its role in apoptosis, oncogenesis, and cancer therapeutics. Biochemical Pharmacology, 162, 250–261. https://doi.org/10.1016/j.bcp.2019.01.015
   PubMed Web of Science ®Google Scholar
• Koohpeyma, F., Siri, M., Allahyari, S., Mahmoodi, M., Saki, F., & Dastghaib, S. (2021). The effects of L-carnitine on renal function and gene expression of caspase-9 and BCL-2 in monosodium glutamate‐induced rats. BMC Nephrology, 22(1), 162. https://doi.org/10.1186/s12882-021-02364-4
   PubMed Web of Science ®Google Scholar
• Korsmeyer, S. J. (1999). BCL-2 gene family and the regulation of programmed cell death. Cancer Research, 59(7), 1693–1700. https://pubmed.ncbi.nlm.nih.gov/10197582/
   Web of Science ®Google Scholar
• Kubista, M., Andrade, J. M., Bengtsson, M., Forootan, A., & Jonak, J. (2006). The real-time polymerase chain reaction. Molecular Aspects of Medicine, 2(3), 95–125. https://doi.org/10.1016/j.mam.2005.12.007
   Google Scholar
• Livak, J. K., & Schmittgen, D. T. (2001). Analysis of relative gene expression data using Real-time quantitative PCR and the 2−ΔΔCT method. Methods [Internet], 25(4), 402–408. https://doi.org/10.1006/meth.2001.1262
   Google Scholar
• Malekinejad, F., Fink-Gremmels, J., & Malekinejad, H. (2022). Zearalenone and its metabolite exposure directs oestrogen metabolism towards potentially carcinogenic metabolites in human breast cancer MCF-7 cells. Mycotoxin Research, 53(1), 45–56. https://doi.org/10.1007/s12550-022-00472-0
   Google Scholar
• Maluly, H. D., Arisseto‐Bragotto, A. P., & Reyes, F. G. (2017). Monosodium glutamate as a tool to reduce sodium in foodstuffs: Technological and safety aspects. Food Science & Nutrition, 5(6), 1039–1048. https://doi.org/10.1002/fsn3.499
   PubMed Web of Science ®Google Scholar
• Masson, L. F., Sharp, L., Cotton, S. C., & Little, J. (2005). Cytochrome P-450 CYP1A1 gene polymorphisms and risk of breast cancer: A Huge review. American Journal of Epidemiology, 161(10), 901–915. https://doi.org/10.1093/aje/kwi121
   PubMed Web of Science ®Google Scholar
• Petersen, D. D., McKinney, C. E., Ikeya, K., Smith, H. H., Bale, A. E., McBride, O. W., & Nebert, D. W. (1991). Human CYP1A1 gene: Cosegregation of the enzyme inducibility phenotype and an RFLP. American Journal of Human Genetics, 48(4), 720. https://pubmed.ncbi.nlm.nih.gov/1707592/
   PubMed Web of Science ®Google Scholar
• Prasath, D., & Surya, S. M. (2013). Detection of genotoxicity and chromosomal aberrations induced by furadan and monosodium glutamate in allium cepa. South Asian Journal of Biological Science, 3(1), 11–24. https://worldveg.tind.io/record/50134#record-files-collapse-header
   Google Scholar
• Renjana, P. K., Anjana, S., & Thoppil, J. E. (2013). Evaluation of genotoxic effects of baking powder and monosodium glutamate using allium cepa assay. International Journal of Pharmacy and Pharmaceutical Science, 5(2), 311–315. https://worldveg.tind.io/record/50133
   Google Scholar
• Soumerai, J. D., Opat, S., Cheah, C. Y., Lasica, M., Verner, E., Peter, J., & Browett, P. J. (2022). CLL-118 a phase 1 study with the novel B-cell lymphoma 2 inhibitor BGB-11417 as monotherapy or in combination with zanubrutinib in patients with B-cell malignancies. Clinical Lymphoma Myeloma and Leukemia, 22(2), 267–268. https://doi.org/10.1016/S2152-2650(22)01326-X
   Google Scholar
• Tolosa, L., Donato, M. T., & Gómez-Lechón, M. J. (2015). General cytotoxicity assessment by means of the MTT assay. In Protocols in in vitro hepatocyte research (pp. 333–348). Humana Press. https://doi.org/10.1007/978-1-4939-2074-7_26
   Google Scholar
• Turkoglu, S. (2015). Evaluation of genotoxic effects of five flavour enhancers (glutamates) on the root meristem cells of allium cepa. Toxicology and Industrial Health, 31(9), 792–801. https://doi.org/10.1177/0748233713475509
   PubMed Web of Science ®Google Scholar
• Uslu, D., & Tosun, H. (2013). Glutamic acid production and general application areas. Electronic Journal of Food Technologies, 8(2), 18–28. www.teknolojikarastirmalar.com
   Google Scholar
• Warren, C. F. A., Wong-Brown, M. W., & Bowden, N. A. (2019). BCL-2 family isoforms in apoptosis and cancer. Cell Death & Disease, 10(3), 177. https://doi.org/10.1038/s41419-019-1407-6
   PubMed Web of Science ®Google Scholar
• Weltin, A., Kieninger, J., & Urban, G. A. (2017). Highly sensitive electrochemical glutamate microsensors for food analysis. Multidisciplinary Digital Publishing Institute Proceedings, 1(4), 521. https://doi.org/10.3390/proceedings1040521
   Google Scholar
• Yoruk, N. G., & Danyer, E. (2016). General information and definitions of food additives. Journal of Food Hygiene and Technology-Special Topics, 2(2), 1–10. https://doi.org/10.31795/baunsobed.580561
   Google Scholar
• Yuzbasioglu, D., Zengin, N., & Unal, F. (2014). Food preservatives and genotoxicity tests. Gıda/The Journal of Food, 39(3), 179–186. https://doi.org/10.5505/gida.24861
   Google Scholar
• Zhang, L., Lu, Z., & Zhao, X. (2021). Targeting BCL-2 for cancer therapy. Biochimica Et Biophysica Acta (BBA) - Reviews on Cancer, 1876(1), 188569. https://doi.org/10.1016/j.bbcan.2021.188569
   PubMed Web of Science ®Google Scholar
• Zhu, W., Liu, H., Wang, X., Lu, J., Zhang, H., Wang, S., & Yang, W. (2019). Associations of CYP1 polymorphisms with risk of prostate cancer: An updated meta-analysis. Bioscience Reports, 39(3), 20181876. https://doi.org/10.1042/BSR20181876
   Google Scholar