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Temperature Volume 4, 2017 - Issue 2
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Front Matter: Discovery

Population data indicate that thyroid regulation is consistent with an equilibrium-point model, but not with a set-point model

Stephen Paul FitzgeraldDepartment of Internal Medicine, Department of Endocrinology, The Royal Adelaide Hospital, Adelaide5000, South Australia;School of Medicine, The University of Adelaide, SA5005, AustraliaCorrespondence[email protected]
,
Nigel Geoffrey BeanSchool Of Mathematical Sciences, The University of Adelaide, SA5005, Australia;ARC Centre of Excellence for Mathematical and Statistical Frontiers, The University of Adelaide, SA5005, Australia
&
Leah Nicole FitzgeraldAdelaide, South Australia, Australia
Pages 114-116 | Published online: 17 Feb 2017

References

  • Fitzgerald SP, Bean NG. The relationship between population T4/TSH set point data and T4/TSH physiology. J Thyroid Res. 2016;2016:6351473. PMID:27123359.
  • Sherwood L. Human Physiology, From Cells to Systems. 6th Edition. Thompson Brooks/Cole; 2007.
  • Fliers E, Kalsbeek A, Boelen A. Beyond the fixed setpoint of the hypothalamus-pituitary-thyroid axis. Eur J Endocrinol. 2014; 171(5):R197-208. PMID: 25005935; doi:10.1530/EJE-14-0285.
  • Dietrich JW, Landgrafe G, Fotiadou EH. TSH and thyrotropic agonists: Key actors in thyroid homeostasis. J Thyroid Res. 2012; 2012:351864.
  • Rubio PP, Gallardo LJ, Duran EA, Sanchez SML. Correlation between the plasma levels of T3, T4 and TSH in a normal population. Rev Clin Esp. 1979;155(4):267-270. PMID:542676.

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