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Commentary

A link between TP53 polymorphisms and metabolism

, &
Article: e1173769 | Received 28 Mar 2016, Accepted 29 Mar 2016, Published online: 31 May 2016

References

  • Levine AJ, Oren M. The first 30 years of p53: growing ever more complex. Nat Rev Cancer 2009; 9:749-758; PMID:19776744; http://dx.doi.org/10.1038/nrc2723
  • Murphy ME. Polymorphic variants in the p53 pathway. Cell Death Differentiation 2006; 13:916-920; PMID:16557270; http://dx.doi.org/10.1038/sj.cdd.4401907
  • NEEL JV. Diabetes mellitus: a “thrifty” genotype rendered detrimental by “progress”? Am J Hum Genet. 1962 Dec;14:353-62. PubMed PMID: 13937884
  • Bonnefond A, Froguel P. Rare and Common Genetic Events in Type 2 Diabetes: What Should Biologists Know? Cell Metab 2015; 21(3):357-68; PMID:25640731; http://dx.doi.org/10.1016/j.cmet.2014.12.020
  • Gaulton KJ, Willer CJ, Li Y, Scott LJ, Conneely KN, Jackson AU, Duren WL, Chines PS, Narisu N, Bonnycastle LL, et al. Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes. Diabetes 2008; 57:3136-3144; PMID:18678618; http://dx.doi.org/10.2337/db07-1731
  • Burgdorf KS, Grarup N, Justesen JM, Harder MN, Witte DR, Jørgensen T, Sandbæk A, Lauritzen T, Madsbad S, Hansen T, et al. Studies of the association of Arg72Pro of tumor suppressor protein p53 with type 2 diabetes in a combined analysis of 55,521 Europeans. PloS One 2011; 6:e15813; PMID:21283750; http://dx.doi.org/10.1371/journal.pone.0015813
  • Kung CP, Leu JI, Basu S, Khaku S, Anokye-Danso F, Liu Q, George DL, Ahima RS, Murphy ME. The P72R Polymorphism of p53 Predisposes to Obesity and Metabolic Dysfunction. Cell Rep 2016; 14:2413-2425; PMID:26947067; http://dx.doi.org/10.1016/j.celrep.2016.02.037
  • Shi H, Tan SJ, Zhong H, Hu W, Levine A, Xiao CJ, Peng Y, Qi XB, Shou WH, Ma RL, et al. Winter temperature and UV are tightly linked to genetic changes in the p53 tumor suppressor pathway in Eastern Asia. Am J Hum Gen 2009; 84:534-541; PMID:19344876; http://dx.doi.org/10.1016/j.ajhg.2009.03.009
  • Levine AJ, Tomasini R, McKeon FD, Mak TW, Melino G. The p53 family: guardians of maternal reproduction. Nature reviews. Mol Cell Biol 2011; 12:259-265; PMID:21427767; http://dx.doi.org/10.1038/nrm3086.
  • Park J, Morley TS, Kim M, Clegg DJ, Scherer PE. Obesity and cancer–mechanisms underlying tumour progression and recurrence. Nature reviews. Endocrinology 2014; 10:455-465; PMID:24935119; http://dx.doi.org/10.1038/nrendo.2014.94

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