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Commentary

Regulation of protein metabolism in cancer

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Article: e1285384 | Received 12 Jan 2017, Accepted 15 Jan 2017, Published online: 10 May 2018

References

  • Bowtell DD, Bohm S, Ahmed AA, Aspuria PJ, Bast RC, Jr, Beral V, Berek JS, Birrer MJ, Blagden S, Bookman MA, et al. Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer. Nat Rev Cancer 2015; 15(11):668-79; PMID:26493647; https://doi.org/10.1038/nrc4019
  • Vander Heiden MG. Targeting cancer metabolism: a therapeutic window opens. Nat Rev Drug Discov 2011; 10(9):671-84; PMID:21878982; https://doi.org/10.1038/nrd3504
  • Yang L, Moss T, Mangala LS, Marini J, Zhao H, Wahlig S, Armaiz-Pena G, Jiang D, Achreja A, Win J, et al. Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer. Mol Syst Biol 2014; 10:728; PMID:24799285; https://doi.org/10.1002/msb.20134892
  • Yang L, Achreja A, Yeung TL, Mangala LS, Jiang D, Han C, Baddour J, Marini JC, Ni J, Nakahara R, et al. Targeting stromal glutamine synthetase in tumors disrupts tumor microenvironment-regulated cancer cell growth. Cell Metab 2016; 24(5):685-700; PMID:27829138; https://doi.org/10.1016/j.cmet.2016.10.011
  • Han C, Yang L, Choi HH, Baddour J, Achreja A, Liu Y, Li Y, Li J, Wan G, Huang C, et al. Amplification of USP13 drives ovarian cancer metabolism. Nat Commun 2016; 7:13525; PMID:27892457; https://doi.org/10.1038/ncomms13525
  • D'Arcy P, Linder S. Proteasome deubiquitinases as novel targets for cancer therapy. Int J Biochem Cell Biol 2012; 44(11):1729-38; PMID:22819849; https://doi.org/10.1016/j.biocel.2012.07.011
  • Ahn CS, Metallo CM. Mitochondria as biosynthetic factories for cancer proliferation. Cancer Metab 2015; 3(1):1; PMID:25621173; https://doi.org/10.1186/s40170-015-0128-2
  • Mullen AR, Hu Z, Shi X, Jiang L, Boroughs LK, Kovacs Z, Boriack R, Rakheja D, Sullivan LB, Linehan WM, et al. Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects. Cell Rep 2014; 7(5):1679-90; PMID:24857658; https://doi.org/10.1016/j.celrep.2014.04.037
  • Chypre M, Zaidi N, Smans K. ATP-citrate lyase: a mini-review. Biochem Biophys Res Commun 2012; 422(1):1-4; PMID:22575446; https://doi.org/10.1016/j.bbrc.2012.04.144
  • Patch AM, Christie EL, Etemadmoghadam D, Garsed DW, George J, Fereday S, Nones K, Cowin P, Alsop K, Bailey PJ, et al. Whole-genome characterization of chemoresistant ovarian cancer. Nature 2015; 521(7553):489-94; PMID:26017449; https://doi.org/10.1038/nature14410

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