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Infectious Diseases Volume 54, 2022 - Issue 4
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Letter to the Editor

Changes in KPC-producing Klebsiella pneumoniae susceptibility from the pre- to ceftazidime-avibactam era

Matteo Boattinia Microbiology and Virology Unit, University Hospital Città della Salute e della Scienza di Torino, Turin, Italy;b Department of Public Health and Paediatrics, University of Torino, Turin, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-6726-2716
ORCID Icon,
Gabriele Biancoa Microbiology and Virology Unit, University Hospital Città della Salute e della Scienza di Torino, Turin, Italy
,
Sara Cominia Microbiology and Virology Unit, University Hospital Città della Salute e della Scienza di Torino, Turin, Italy;b Department of Public Health and Paediatrics, University of Torino, Turin, Italy
,
Marco Iannacconea Microbiology and Virology Unit, University Hospital Città della Salute e della Scienza di Torino, Turin, Italy
,
Roberto Casalea Microbiology and Virology Unit, University Hospital Città della Salute e della Scienza di Torino, Turin, Italy;b Department of Public Health and Paediatrics, University of Torino, Turin, Italy
,
Lorena Charrierb Department of Public Health and Paediatrics, University of Torino, Turin, Italy
,
Rossana Cavalloa Microbiology and Virology Unit, University Hospital Città della Salute e della Scienza di Torino, Turin, Italy;b Department of Public Health and Paediatrics, University of Torino, Turin, Italy
&
Cristina Costaa Microbiology and Virology Unit, University Hospital Città della Salute e della Scienza di Torino, Turin, Italy;b Department of Public Health and Paediatrics, University of Torino, Turin, Italy
 show all
Pages 311-313 | Received 20 Nov 2021, Accepted 24 Nov 2021, Published online: 06 Dec 2021

References

  • Assimakopoulos SF, Lazaris V, Papadimitriou-Olivgeris M, et al. Predictors of mortality for KPC-producing Klebsiella pneumoniae bloodstream infections in adult neutropenic patients with haematological malignancies. Infect Dis. 2020;52(6):446–449.
  • Pintado V, Ruiz-Garbajosa P, Escudero-Sanchez R, et al. Carbapenemase-producing enterobacterales infections in COVID-19 patients. Infect Dis. 2021:1–10. DOI:https://doi.org/10.1080/23744235.2021.1963471
  • Di Bella S, Giacobbe DR, Maraolo AE, et al. Resistance to ceftazidime/avibactam in infections and colonisations by KPC-producing enterobacterales: a systematic review of observational clinical studies. J Glob Antimicrob Resist. 2021;25:268–281.
  • Shields RK, Nguyen MH, Chen L, et al. Ceftazidime-avibactam is superior to other treatment regimens against carbapenem-resistant Klebsiella pneumoniae bacteremia. Antimicrob Agents Chemother. 2017;61(8):e00883-17.
  • Foschi C, Lombardo D, Gaibani P, et al. Carbapenemase-producing enterobacterales: changing epidemiology in a highly endemic Italian area. J Hosp Infect. 2021;108:221–223.
  • Fiore M, Alfieri A, Di Franco S, et al. Ceftazidime-avibactam combination therapy compared to ceftazidime-avibactam monotherapy for the treatment of severe infections due to carbapenem-resistant pathogens: a systematic review and network meta-analysis. Antibiotics. 2020;9(7):388.
  • Monaco M, Giani T, Raffone M, et al. Colistin resistance superimposed to endemic carbapenem-resistant Klebsiella pneumoniae: a rapidly evolving problem in Italy, November 2013 to April 2014. Euro Surveill. 2014;19:20939.
  • Galani I, Karaiskos I, Karantani I, et al. Epidemiology and resistance phenotypes of carbapenemase-producing Klebsiella pneumoniae in Greece, 2014 to 2016. Euro Surveill. 2018;23(31):1700775.
  • Bianco G, Boattini M, Iannaccone M, et al. Carbapenemase detection testing in the era of ceftazidime/avibactam-resistant KPC-producing enterobacterales: a 2-year experience. J Glob Antimicrob Resist. 2021;24:411–414.

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