Advanced search
Publication Cover
Infectious Diseases Volume 54, 2022 - Issue 6
Submit an article Journal homepage
1,048
Views
3
CrossRef citations to date
0
Altmetric
Brief Report

Low pre-vaccination SARS-CoV-2 seroprevalence in Finnish health care workers: a prospective cohort study

Paula A. Tähtinena Department of Paediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, FinlandCorrespondence[email protected]
View further author information
,
Lauri Ivaskaa Department of Paediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, FinlandView further author information
,
Pinja Jalkanenb Infections and Immunity Unit, Institute of Biomedicine, University of Turku, Turku, FinlandView further author information
,
Laura Kakkolab Infections and Immunity Unit, Institute of Biomedicine, University of Turku, Turku, FinlandView further author information
,
Leena Kainulainena Department of Paediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, FinlandView further author information
,
Jukka Hytönenb Infections and Immunity Unit, Institute of Biomedicine, University of Turku, Turku, Finland;c Clinical Microbiology Division, Turku University Hospital, Turku, FinlandView further author information
,
Tytti Vuorinenb Infections and Immunity Unit, Institute of Biomedicine, University of Turku, Turku, Finland;c Clinical Microbiology Division, Turku University Hospital, Turku, FinlandView further author information
,
Matti Warisb Infections and Immunity Unit, Institute of Biomedicine, University of Turku, Turku, Finland;c Clinical Microbiology Division, Turku University Hospital, Turku, FinlandView further author information
,
Ville Peltolaa Department of Paediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, FinlandView further author information
,
Jarmo Oksid Department of Infectious Diseases, Turku University Hospital and University of Turku, Turku, FinlandView further author information
,
Ilkka Julkunenb Infections and Immunity Unit, Institute of Biomedicine, University of Turku, Turku, Finland;c Clinical Microbiology Division, Turku University Hospital, Turku, FinlandView further author information
&
Johanna Lempainena Department of Paediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, Finland;c Clinical Microbiology Division, Turku University Hospital, Turku, Finland;e Immunogenetics Laboratory, Institute of Biomedicine, University of Turku, Turku, FinlandView further author information
 show all
Pages 448-454 | Received 12 Sep 2021, Accepted 02 Jan 2022, Published online: 19 Jan 2022

References

  • Calcagno A, Ghisetti V, Emanuele T, et al. Risk for SARS-CoV-2 infection in healthcare workers, turin, Italy. Emerg Infect Dis. 2021;27(1):303–305.
  • Shah AV, Wood R, Gribben C, et al. Risk of hospital admission with coronavirus disease 2019 in healthcare workers and their households: nationwide linkage cohort study. BMJ. 2020;371:m3582.
  • Pan A, Liu L, Wang C, et al. Association of public health interventions with the epidemiology of the COVID-19 outbreak in Wuhan, China. JAMA. 2020;323(19):1915–1923.
  • Houlihan CF, Vora N, Byrne T, et al. Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers. Lancet. 2020;396(10246):e6–e7.
  • Iversen K, Bundgaard H, Hasselbalch RB, et al. Risk of COVID-19 in health-care workers in Denmark: an observational cohort study. Lancet Infect Dis. 2020;20(12):1401–1408.
  • Steensels D, Oris E, Coninx L, et al. Hospital-Wide SARS-CoV-2 antibody screening in 3056 staff in a tertiary center in Belgium. JAMA. 2020;324(2):195–197.
  • Jacob JT, Baker JM, Fridkin SK, et al. Risk factors associated with SARS-CoV-2 seropositivity among US health care personnel. JAMA Netw Open. 2021;4(3):e211283.
  • COVID-19 situation update for the EU/EEA, as of 10 Sep 2021. Solna (Sweden): European Centre for Disease Prevention and Control; 2021 [cited 2021 Sep 12]. Available from: https://www.ecdc.europa.eu/en/cases-2019-ncov-eueea.
  • Situation update on coronavirus - infectious diseases and vaccinations - THL. Helsinki (Finland): Finnish Institute for Health and Welfare; 2021 [cited 2021 Sep 12]. Available from: https://thl.fi/en/web/infectious-diseases-and-vaccinations/what-s-new/coronavirus-covid-19-latest-updates/situation-update-on-coronavirus#Coronavirus_situation.
  • Jalkanen P, Pasternack A, Maljanen S, et al. A combination of N and S antigens with IgA and IgG measurement strengthens the accuracy of SARS-CoV-2 serodiagnostics. J Infect Dis. 2021;224(2):218–228.
  • Jalkanen P, Kolehmainen P, Häkkinen HK, et al. COVID-19 mRNA vaccine induced antibody responses against three SARS-CoV-2 variants. Nat Commun. 2021;12(1):3991.
  • Röltgen K, Powell AE, Wirtz O, et al. Defining the features and duration of antibody responses to SARS-CoV-2 infection associated with disease severity and outcome. Sci Immunol. 2020;5(54):eabe0240.
  • Wei J, Matthews PC, Stoesser N, et al. Anti-spike antibody response to natural SARS-CoV-2 infection in the general population. Nat Commun. 2021;12(1):6250.
  • Petersen LR, Sami S, Vuong N, et al. Lack of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a large cohort of previously infected persons. Clin Infect Dis. 2021;73(9):e3066–e3073.
  • Egia-Mendikute L, Bosch A, Prieto-Fernández E, et al. Sensitive detection of SARS-CoV-2 seroconversion by flow cytometry reveals the presence of nucleoprotein-reactive antibodies in unexposed individuals. Commun Biol. 2021;4(1):486.
  • Ren L, Zhang L, Chang D, et al. The kinetics of humoral response and its relationship with the disease severity in COVID-19. Commun Biol. 2020;3(1):780.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.