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Infectious Diseases Volume 54, 2022 - Issue 11
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Brief Report

Immunity waning after COVID vaccine booster vs. infection—better than expected

Johad Khourya Pulmonology Division, Lady Davis-Carmel Medical Center, Haifa, Israel;b EMMS Nazareth, Nazareth, Israel;c Department of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT, USACorrespondence[email protected]
,
Ronza Najjar-Debbinyb EMMS Nazareth, Nazareth, Israel;c Department of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT, USA;d Department of Infection Control and Prevention, Lady Davis-Carmel Medical Center, Haifa, Israel
,
Ameer Elemyb EMMS Nazareth, Nazareth, Israel
,
Adel Jabboure Medical Laboratory, EMMS, Nazareth, Israel
,
Juliana Hajf Nephrology Department, EMMS, Nazareth, Israel
,
Majdolen Abu-Sinic Department of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT, USA
,
Rabah Yasing Internal Medicine Department, EMMS, Nazareth, Israel
,
Mohammad Aming Internal Medicine Department, EMMS, Nazareth, Israel
,
Elias Hellouh Cardiology Department, EMMS, Nazareth, Israel
,
Najib Nasrallahi Department Emergency Medicine, EMMS, Nazareth, Israel
,
Amer Saffourie Medical Laboratory, EMMS, Nazareth, Israel
&
Fahed Hakimj Department Pediatric Pulmonology, The Brain, Sleep and Immunity Laboratory, EMMS, Nazareth, Israel;k Bar-Ilan University School of Medicine, Ramat Gan, Israel
 show all
Pages 828-831 | Received 17 Apr 2022, Accepted 28 Jun 2022, Published online: 07 Jul 2022

References

  • Bergwerk M, Gonen T, Lustig Y, et al. Covid-19 breakthrough infections in vaccinated health care workers. N Engl J Med. 2021;385(16):1474–1484.
  • Burki TK. Fourth dose of COVID-19 vaccines in Israel. Lancet Respir Med. 2022;10(2):e19.
  • Levin EG, Lustig Y, Cohen C, et al. Waning immune humoral response to BNT162b2 covid-19 vaccine over 6 months. N Engl J Med. 2021;385(24):e84.
  • Khoury J, Najjar-Debbiny R, Hanna A, et al. COVID-19 vaccine – long term immune decline and breakthrough infections. Vaccine. 2021;39(48):6984–6989.
  • Bar-On YM, Goldberg Y, Mandel M, et al. Protection of BNT162b2 vaccine booster against covid-19 in Israel. N Engl J Med. 2021;385(15):1393–1400.
  • FDA. COVID-19 vaccine manufacturers submit appeals to FDA for fourth dose. In: Coronavirus (COVID-19) update: FDA to Hold Advisory Committee Meeting on COVID-19 Vaccines to Discuss Future Boosters; 2022. Available from: https://content.govdelivery.com/accounts/USFDA/bulletins/30fc220
  • FDA. Coronavirus (COVID-19) update: FDA authorizes second booster dose of two COVID-19 vaccines for older and immunocompromised individuals; 2022.
  • Coppeta L, Somma G, Ferrari C, et al. Persistence of anti-S titre among healthcare workers vaccinated with BNT162b2 mRNA COVID-19. Vaccines. 2021;9(9):947.
  • Coppeta L, Ferrari C, Somma G, et al. Reduced titers of circulating anti-SARS-CoV-2 antibodies and risk of COVID-19 infection in healthcare workers during the nine months after immunization with the BNT162b2 mRNA vaccine. Vaccines. 2022;10(2):141.
  • Health IMo: COVID-19 updates; 2022.
  • Polack FP, Thomas SJ, Kitchin N, et al. Safety and efficacy of the BNT162b2 mRNA covid-19 vaccine. N Engl J Med. 2020;383(27):2603–2615.
  • Desai AD, Lavelle M, Boursiquot BC, et al. Long-term complications of COVID-19. Am J Physiol Cell Physiol. 2022;322(1):C1–C11.
  • Zhao J, Yuan Q, Wang H, et al. Antibody responses to SARS-CoV-2 in patients with novel coronavirus disease 2019. Clin Infect Dis. 2020;71(16):2027–2034.

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