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Research Articles

Bacterial and fungal infections: a frequent and deadly complication among critically ill acute liver failure patients

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Pages 480-489 | Received 31 Mar 2023, Accepted 07 May 2023, Published online: 21 May 2023

References

  • Bernal W, Wendon J. Acute liver failure. N Engl J Med. 2013;369(26):2525–2534.
  • Stravitz RT, Lee WM. Acute liver failure. Lancet. 2019;394(10201):869–881.
  • Bernal W, Auzinger G, Dhawan A, et al. Acute liver failure. Lancet. 2010;376(9736):190–201. 
  • Reuben A, Tillman H, Fontana RJ, et al. Outcomes in adults with acute liver failure between 1998 and 2013: an observational cohort study. Ann Intern Med. 2016;164(11):724–732.
  • Germani G, Theocharidou E, Adam R, et al. Liver transplantation for acute liver failure in Europe: outcomes over 20 years from the ELTR database. J Hepatol. 2012;57(2):288–296.
  • Bernal W, Cross TJS, Auzinger G, et al. Outcome after wait-listing for emergency liver transplantation in acute liver failure: a single centre experience. J Hepatol. 2009;50(2):306–313.
  • Antoniades CG, Berry PA, Wendon JA, et al. The importance of immune dysfunction in determining outcome in acute liver failure. J Hepatol. 2008;49(5):845–861.
  • Rolando N, Philpott-Howard J, Williams R. Bacterial and fungal infection in acute liver failure. Semin Liver Dis. 1996;16(4):389–402.
  • Rolando N, Harvey F, Brahm J, et al. Prospective study of bacterial infection in acute liver failure: an analysis of fifty patients. Hepatology. 1990;11(1):49–53.
  • Wendon J, Cordoba J, Dhawan A, et al. EASL clinical practical guidelines on the management of acute (fulminant) liver failure. J Hepatol. 2017;66(5):1047–1081.
  • Stravitz RT, Kramer AH, Davern T, et al. Intensive care of patients with acute liver failure: recommendations of the U.S. Acute Liver Failure Study Group. Crit Care Med. 2007;35(11):2498–2508.
  • Paugam-Burtz C, Levesque E, Louvet A, et al. Management of liver failure in general intensive care unit. Anaesth Crit Care Pain Med. 2020;39(1):143–161.
  • Rhodes A, Evans LE, Alhazzani W, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016. Intensive Care Med. 2017;43(3):304–377.
  • Camus C, Lavoué S, Gacouin A, et al. Molecular Adsorbent Recirculating System dialysis in patients with acute liver failure who are assessed for liver transplantation. Intensive Care Med. 2006;32(11):1817–1825.
  • Larsen FS, Schmidt LE, Bernsmeier C, et al. High-volume plasma exchange in patients with acute liver failure: an open randomised controlled trial. J Hepatol. 2016;64(1):69–78.
  • O'Grady JG, Schalm SW, Williams R. Acute liver failure: redefining the syndromes. Lancet. 1993;342(8866):273–275.
  • Bernuau J, Goudeau A, Poynard T, et al. Multivariate analysis of prognostic factors in fulminant hepatitis B. Hepatology. 1986;6(4):648–651.
  • Bernuau J, Rueff B, Benhamou J-P. Fulminant and subfulminant liver failure: definitions and causes. Semin Liver Dis. 1986;6(2):97–106.
  • Escudié L, Francoz C, Vinel J-P, et al. Amanita phalloides poisoning: reassessment of prognostic factors and indications for emergency liver transplantation. J Hepatol. 2007;46(3):466–473.
  • Camus C, Bellissant E, Sebille V, et al. Prevention of acquired infections in intubated patients with the combination of two decontamination regimens. Crit Care Med. 2005;33(2):307–314.
  • Camus C, Salomon S, Bouchigny C, et al. Short-term decline in all-cause acquired infections with the routine use of a decontamination regimen combining topical polymyxin, tobramycin, and amphotericin B with mupirocin and chlorhexidine in the ICU: a single-center experience. Crit Care Med. 2014;42(5):1121–1130.
  • European Association for the Study of the Liver. EASL Clinical Practice Guidelines on the management of hepatic encephalopathy. J Hepatol. 2022;77:807–824.
  • Le Gall JR, Lemeshow S, Saulnier F. A new Simplified Acute Physiology Score (SAPS II) based on a European/North American Multicenter Study. JAMA. 1993;270(24):2957–2963.
  • Vincent JL, Moreno R, Takala J, et al. The SOFA (Sepsis-Related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related problems of the European Society of Intensive Care Medicine. Intensive Care Med. 1996;22(7):707–710.
  • Kamath PS, Wiesner RH, Malinchoc M, et al. A model to predict survival in patients with end-stage liver disease. Hepatology. 2001;33(2):464–470.
  • Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control. 2008;36(5):309–332.
  • Blot SI, Taccone FS, Van den Abeele A-M, et al. A clinical algorithm to diagnose invasive pulmonary aspergillosis in critically ill patients. Am J Respir Crit Care Med. 2012;186(1):56–64.
  • O'Grady JG, Alexander GJ, Hayllar KM, et al. Early indicators of prognosis in fulminant hepatic failure. Gastroenterology. 1989;97(2):439–445.
  • Koch DG, Tillman H, Durkalski V, et al. Development of a model to predict transplant-free survival of patients with acute liver failure. Clin Gastroenterol Hepatol. 2016;14(8):1199–1206.e2.
  • Rolando N, Wade J, Davalos M, et al. The systemic inflammatory response syndrome in acute liver failure. Hepatology. 2000;32(4 Pt 1):734–739.
  • Karvellas CJ, Pink F, McPhail M, et al. Predictors of bacteraemia and mortality in patients with acute liver failure. Intensive Care Med. 2009;35(8):1390–1396.
  • Karvellas CJ, Cavazos J, Battenhouse H, et al. Effects of antimicrobial prophylaxis and blood stream infections in patients with acute liver failure: a retrospective cohort study. Clin Gastroenterol Hepatol. 2014;12(11):1942–1949.e1.
  • Malacarne P, Langer M, Nascimben E, et al. Building a continuous multicenter infection surveillance system in the intensive care unit: findings from the initial data set of 9,493 patients from 71 Italian intensive care units. Crit Care Med. 2008;36(4):1105–1113.
  • SepNet Critical Care Trials Group. Incidence of severe sepsis and septic shock in German intensive care units: the prospective, multicentre INSEP study. Intensive Care Med. 2016;42:1980–1989.
  • Camus C, Sauvadet E, Tavenard A, et al. Decline of multidrug-resistant gram negative infections with the routine use of a multiple decontamination regimen in ICU. J Infect. 2016;73(3):200–209.
  • Wyke RJ, Rajkovic IA, Eddleston AL, et al. Defective opsonisation and complement deficiency in serum from patients with fulminant hepatic failure. Gut. 1980;21(8):643–649.
  • Clapperton M, Rolando N, Sandoval L, et al. Neutrophil superoxide and hydrogen peroxide production in patients with acute liver failure. Eur J Clin Invest. 1997;27(2):164–168.
  • Rolando N, Clapperton M, Wade J, et al. Administering granulocyte colony-stimulating factor to acute liver failure patients corrects neutrophil defects. Eur J Gastroenterol Hepatol. 2000;12(12):1323–1328.
  • Antoniades CG, Berry PA, Davies ET, et al. Reduced monocyte HLA-DR expression: a novel biomarker of disease severity and outcome in acetaminophen-induced acute liver failure. Hepatology. 2006;44(1):34–43.
  • Verma N, Singh S, Singh M, et al. Global epidemiological burden of fungal infections in cirrhosis patients: a systematic review with meta-analysis. Mycoses. 2022;65(3):266–284.
  • Falcone M, Massetti AP, Russo A, et al. Invasive aspergillosis in patients with liver disease. Med Mycol. 2011;49(4):406–413.

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