Comparative evaluation of the clinical presentation and epidemiology of the 2022 and previous Mpox outbreaks: a rapid review and meta-analysis

References

• U.S. Department of Health & Human Services. 2022 Monkeypox outbreak global map. 2022 [cited 2022 Aug 18]. Available from: https://www.cdc.gov/poxvirus/monkeypox/response/2022/world-map.html
   Google Scholar
• World Health Organization. Monkeypox outbreak 2022. The WHO. 2022 [cited 2022 Aug 18]. Available from: https://www.who.int/emergencies/situations/monkeypox-oubreak-2022
   Google Scholar
• Sklenovska N, Van Ranst M. Emergence of monkeypox as the most important orthopoxvirus infection in humans. Front Public Health. 2018;6(241):241.
   PubMedGoogle Scholar
• Parker S, Buller RM. A review of experimental and natural infections of animals with monkeypox virus between 1958 and 2012. Future Virol. 2013;8(2):129–157.
   PubMed Web of Science ®Google Scholar
• Hutson CL, Nakazawa YJ, Self J, et al. Laboratory investigations of African Pouched Rats (Cricetomys gambianus) as a potential reservoir host species for monkeypox virus. PLOS Negl Trop Dis. 2015;9(10):e0004013.
   PubMed Web of Science ®Google Scholar
• Simpson K, Heymann D, Brown CS, et al. Human monkeypox – after 40 years, an unintended consequence of smallpox eradication. Vaccine. 2020;38(33):5077–5081.
   PubMed Web of Science ®Google Scholar
• Falendysz EA, Lopera JG, Doty JB, et al. Characterization of monkeypox virus infection in African rope squirrels (Funisciurus sp.). PLOS Negl Trop Dis. 2017;11(8):e0005809.
   PubMed Web of Science ®Google Scholar
• Arita I, Henderson DA. Smallpox and monkeypox in non-human primates. Bull World Health Organ. 1968;39(2):277–283.
   PubMed Web of Science ®Google Scholar
• Vaughan A, Aarons E, Astbury J, et al. Human-to-human transmission of monkeypox virus, United Kingdom, October 2018. Emerg Infect Dis. 2020;26(4):782–785.
   PubMed Web of Science ®Google Scholar
• Hutson CL, Carroll DS, Gallardo-Romero N, et al. Monkeypox disease transmission in an experimental setting: prairie dog animal model. PLOS One. 2011;6(12):e28295.
   PubMed Web of Science ®Google Scholar
• Jezek Z, Grab B, Szczeniowski MV, et al. Human monkeypox: secondary attack rates. Bull World Health Organ. 1988;66(4):465–470.
   PubMed Web of Science ®Google Scholar
• World Health Organization. Monkeypox: key facts. 2022 [cited 2022 Aug 18]. Available from: https://www.who.int/news-room/fact-sheets/detail/monkeypox
   Google Scholar
• Government of Canada. Monkeypox: Symptoms, getting tested, what to do if you’re infected or were exposed. 2022 [cited 2022 Aug 18]. Available from: https://www.canada.ca/en/public-health/services/diseases/monkeypox/symptoms-management.html
   Google Scholar
• World Health Organization. Second meeting of the International Health Regulations (2005) (IHR) Emergency Committee regarding the multi-country outbreak of monkeypox. 2022 [cited 2022 Aug 18]. Available from: https://www.who.int/news/item/23-07-2022-second-meeting-of-the-international-health-regulations-(2005)-(ihr)-emergency-committee-regarding-the-multi-country-outbreak-of-monkeypox
   Google Scholar
• Thornhill JP, Barkati S, Walmsley S, et al. Monkeypox virus infection in humans across 16 Countries – April–June 2022. N Engl J Med. 2022;387(8):e69–691.
   PubMed Web of Science ®Google Scholar
• Americo JL, Earl PL, Moss B. Virulence differences of mpox (monkeypox) virus clades I, IIa, and IIb.1 in a small animal model. Proc Natl Acad Sci U S A. 2023;120(8):e2220415120.
   PubMedGoogle Scholar
• Adler H, Gould S, Hine P, et al. Clinical features and management of human monkeypox: a retrospective observational study in the UK. Lancet Infect Dis. 2022;22(8):1153–1162.
   PubMed Web of Science ®Google Scholar
• Brown K, Leggat PA. Human monkeypox: current state of knowledge and implications for the future. TropicalMed. 2016;1(1):8.
   Google Scholar
• European Medicines Agency. Tecovirimat SIGA. 2022 [cited 2022 Aug 18]. Available from: https://www.ema.europa.eu/en/medicines/human/EPAR/tecovirimat-siga
   Google Scholar
• Siegrist EA, Sassine J. Antivirals with activity against mpox: a clinically oriented review. Clin Infect Dis. 2023;76(1):155–164.
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and Prevention. Treatment information for healthcare professionals. U.S. Department of Health & Human Services. 2023 [cited 2023 Apr 12]. Available from: https://www.cdc.gov/poxvirus/mpox/clinicians/treatment.html#:∼:text=The%20medical%20countermeasures%20currently%20available,Cidofovir%20is%20also%20available%20commercially
   Google Scholar
• World Health Organization. WHO handbook for guideline development. 2nd ed. Vol 11. Geneva, Switzerland: World Health Organization; 2014 [cited 2022 Nov 10]. Available from: https://apps.who.int/iris/handle/10665/145714
   Google Scholar
• Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71.
   PubMed Web of Science ®Google Scholar
• McGowan J, Sampson M, Salzwedel DM, et al. PRESS peer review of electronic search strategies: 2015 guideline statement. J Clin Epidemiol. 2016;75:40–46.
   PubMed Web of Science ®Google Scholar
• EndNote [computer program]. Version EndNote X9. Philadelphia, PA: Clarivate; 2013.
   Google Scholar
• Shaw FE, Kohl Ks, Lee L, et al. Introduction: supplements. MMWR Morb Mortal Wkly Rep. 2011;60(04):2–6.
   Google Scholar
• Sterne JAC, Savovic J, Page MJ, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019;366:l4898.
   PubMed Web of Science ®Google Scholar
• Wells G, Shea B, O’Connell D, et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analysis. Ottawa: Ottawa Hospital Research Institute; 2011 [cited 2023 Feb 9]. Available from: http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp
   Google Scholar
• Abesig J, Chen Y, Wang H, et al. Prevalence of viral hepatitis B in Ghana between 2015 and 2019: a systematic review and meta-analysis. PLOS One. 2020;15(6):e0234348.
   PubMed Web of Science ®Google Scholar
• National Institutes of Health. Quality assessment tool for case series studies. National Heart, Lung, and Blood Institute. [cited 2022 Oct 27]. Available from: https://www.nhlbi.nih.gov/health-topics/study-quality-assessment-tools
   Google Scholar
• Centre for Reviews and Dissemination. Systematic reviews: CRD’s guidance for undertaking reviews in health care. New York: University of York; 2008.
   Google Scholar
• Lin LF, Xu C. Arcsine-based transformations for meta-analysis of proportions: pros, cons, and alternatives. Health Sci Rep. 2020;3(3):e178.
   PubMedGoogle Scholar
• Doi SA, Xu C. The Freeman-Tukey double arcsine transformation for the meta-analysis of proportions: recent criticisms were seriously misleading. J Evid Based Med. 2021;14(4):259–261.
   PubMedGoogle Scholar
• Newcombe RG. Two-sided confidence intervals for the single proportion: comparison of seven methods. Statist Med. 1998;17(8):857–872.
   PubMed Web of Science ®Google Scholar
• DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7(3):177–188.
   PubMedGoogle Scholar
• Shi J, Luo D, Wan X. Detecting the skewness of data from the sample size and the five-number summary [preprint]. arXiv preprint. 2020 [cited 2023 Jan 10]. Available from: https://arxiv.org/pdf/2010.05749.pdf
   Google Scholar
• Luo D, Wan X, Liu J, et al. Optimally estimating the sample mean from the sample size, median, mid-range, and/or mid-quartile range. Stat Methods Med Res. 2018;27(6):1785–1805.
   PubMed Web of Science ®Google Scholar
• Wan X, Wang W, Liu J, et al. Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range. BMC Med Res Methodol. 2014;14:135.
   PubMed Web of Science ®Google Scholar
• Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21(11):1539–1558.
   PubMed Web of Science ®Google Scholar
• Anderson MG, Frenkel LD, Homann S, et al. A case of severe monkeypox virus disease in an American child: emerging infections and changing professional values. Pediatr Infect Dis J. 2003;22(12):1093–1096.
   PubMed Web of Science ®Google Scholar
• Anonymous Update: multistate outbreak of monkeypox –Illinois, Indiana, Kansas, Missouri, Ohio, and Wisconsin, 2003. MMWR. 2003;52(26):616–618.
   Google Scholar
• Antinori A, Mazzotta V, Vita S, et al. Epidemiological, clinical and virological characteristics of four cases of monkeypox support transmission through sexual contact, Italy, May 2022. Euro Surveill. 2022;27(22):2200421.
   PubMedGoogle Scholar
• Benatti SV, Venturelli S, Comi N, et al. Ophthalmic manifestation of monkeypox infection. Lancet Infect Dis. 2022;22(9):1397.
   PubMed Web of Science ®Google Scholar
• Besombes C, Gonofio E, Konamna X, et al. Intrafamily transmission of monkeypox virus, Central African Republic, 2018. Emerg Infect Dis. 2019;25(8):1602–1604.
   PubMed Web of Science ®Google Scholar
• Boesecke C, Monin MB, van Bremen K, et al. Severe monkeypox-virus infection in undiagnosed advanced HIV infection. Infection. 2022;50(6):1633–1634.
   PubMed Web of Science ®Google Scholar
• Brito Caldeira M, Fernandes C. Cutaneous lesions from monkeypox infection. Sex Transm Dis. 2022;49(9):595.
   PubMed Web of Science ®Google Scholar
• Brundu M, Marinello S, Scaglione V, et al. The first case of monkeypox virus and acute HIV infection: should we consider monkeypox a new possible sexually transmitted infection? J Dermatol. 2023;50(3):383–386.
   PubMedGoogle Scholar
• Bruno G, Fabrizio C, Rodano L, et al. Monkeypox in a 71-year-old woman. J Med Virol. 2022;95(1):e27993.
   PubMed Web of Science ®Google Scholar
• Carannante N, Tiberio C, Bellopede R, et al. Monkeypox clinical features and differential diagnosis: first case in Campania region. Pathogens. 2022;11(8):869.
   PubMed Web of Science ®Google Scholar
• Catala A, Clavo-Escribano P, Riera-Monroig J, et al. Monkeypox outbreak in Spain: clinical and epidemiological findings in a prospective cross-sectional study of 185 cases. Br J Dermatol. 2022;187(5):765–772.
   PubMed Web of Science ®Google Scholar
• Croft DR, Sotir MJ, Williams CJ, et al. Occupational risks during a monkeypox outbreak, Wisconsin, 2003. Emerg Infect Dis. 2007;13(8):1150–1157.
   PubMed Web of Science ®Google Scholar
• Davido B, D'Anglejan E, Baudoin R, et al. Monkeypox outbreak 2022: an unusual case of peritonsillar abscess in a person previously vaccinated against smallpox. J Travel Med. 2022;29(6):taac082.
   PubMed Web of Science ®Google Scholar
• De Baetselier I, Van Dijck C, Kenyon C, et al. Retrospective detection of asymptomatic monkeypox virus infections among male sexual health clinic attendees in Belgium. Nat Med. 2022;28(11):2288–2292.
   PubMed Web of Science ®Google Scholar
• de Nicolas-Ruanes B, Vivancos MJ, Azcarraga-Llobet C, et al. Monkeypox virus case with maculopapular exanthem and proctitis during the Spanish outbreak in 2022. J Eur Acad Dermatol. 2022;36(8):E658–E660.
   Web of Science ®Google Scholar
• de Sousa D, Patrocinio J, Frade J, et al. Human monkeypox coinfection with acute HIV: an exuberant presentation. Int J STD AIDS. 2022;33(10):936–938.
   PubMed Web of Science ®Google Scholar
• Desai AN, Thompson GR III, Neumeister SM, et al. Compassionate use of tecovirimat for the treatment of monkeypox infection. JAMA. 2022;328(13):1348–1350.
   PubMed Web of Science ®Google Scholar
• Doshi RH, Alfonso VH, Morier D, et al. Monkeypox rash severity and animal exposures in the democratic republic of the Congo. Ecohealth. 2020;17(1):64–73.
   PubMed Web of Science ®Google Scholar
• Eke RA. Monkey-pox in a four-year old girl: case report. West Afr Med J Niger Pract. 1972;21(1):21–22.
   PubMedGoogle Scholar
• Erez N, Achdout H, Milrot E, et al. Diagnosis of imported monkeypox, Israel, 2018. Emerg Infect Dis. 2019;25(5):980–983.
   PubMed Web of Science ®Google Scholar
• Fang Yong SE, Ng OT, Ho ZJM, et al. Imported monkeypox, Singapore. Emerg Infect Dis. 2020;26(8):1826–1830.
   PubMed Web of Science ®Google Scholar
• Girometti N, Byrne R, Bracchi M, et al. Demographic and clinical characteristics of confirmed human monkeypox virus cases in individuals attending a sexual health centre in london, UK: an observational analysis. Lancet Infect Dis. 2022;22(9):1321–1328.
   PubMed Web of Science ®Google Scholar
• Guzzetta G, Mammone A, Ferraro F, et al. Early estimates of monkeypox incubation period, generation time, and reproduction number, Italy, May–June 2022. Emerg Infect Dis. 2022;28(10):2078–2081.
   PubMed Web of Science ®Google Scholar
• Hammerschlag Y, MacLeod G, Papadakis G, et al. Monkeypox infection presenting as genital rash, Australia, May 2022. Euro Surveill. 2022;27(22):2200411.
   PubMedGoogle Scholar
• Hobson G, Adamson J, Adler H, et al. Family cluster of three cases of monkeypox imported from Nigeria to the United Kingdom, May 2021. Euro Surveill. 2021;26(32):2100745.
   PubMedGoogle Scholar
• Hoff NA, Morier DS, Kisalu NK, et al. Varicella coinfection in patients with active monkeypox in the democratic republic of the Congo. Ecohealth. 2017;14(3):564–574.
   PubMed Web of Science ®Google Scholar
• Hoffmann C, Jessen H, Wyen C, et al. Monkeypox in Germany-initial clinical observations. Dtsch Arztebl Int. 2022;119(33–34):551–557.
   PubMedGoogle Scholar
• Hughes CM, Liu L, Davidson WB, et al. A tale of two viruses: coinfections of monkeypox and varicella zoster virus in the democratic republic of Congo. Am J Trop Med Hyg. 2020;104(2):604–611.
   PubMed Web of Science ®Google Scholar
• Huhn GD, Bauer AM, Yorita K, et al. Clinical characteristics of human monkeypox, and risk factors for severe disease. Clin Infect Dis. 2005;41(12):1742–1751.
   PubMed Web of Science ®Google Scholar
• Hutin YJF, Williams RJ, Malfait P, et al. Outbreak of human monkeypox, democratic republic of Congo, 1996–1997. Emerg Infect Dis. 2001;7(3):434–438.
   PubMed Web of Science ®Google Scholar
• Iñigo Martínez J, Gil Montalbán EG, Jiménez Bueno S, et al. Monkeypox outbreak predominantly affecting men who have sex with men, Madrid, Spain, 26 April–16 June 2022. Euro Surveill. 2022;27(27):2200471.
   PubMedGoogle Scholar
• Jang YR, Lee M, Shin H, et al. The first case of monkeypox in the Republic of Korea. J Korean Med Sci. 2022;37(27):e224.
   PubMed Web of Science ®Google Scholar
• Karan A, Styczynski AR, Huang CH, et al. Human monkeypox without viral prodrome or sexual exposure, California, USA, 2022. Emerg Infect Dis. 2022;28(10):2121–2123.
   PubMed Web of Science ®Google Scholar
• Kreuter A, Grossmann M, Muller VL, et al. Monkeypox infection with concomitant penile lymphoedema. J Eur Acad Dermatol Venereol. 2023;37(3):e431–e432.
   PubMed Web of Science ®Google Scholar
• Lapa D, Carletti F, Mazzotta V, et al. Monkeypox virus isolation from a semen sample collected in the early phase of infection in a patient with prolonged seminal viral shedding. Lancet Infect Dis. 2022;22(9):1267–1269.
   PubMed Web of Science ®Google Scholar
• Lucar J, Roberts A, Saardi KM, et al. Monkeypox virus-associated severe proctitis treated with oral tecovirimat: a report of two cases. Ann Intern Med. 2022;175(11):1626–1627.
   PubMed Web of Science ®Google Scholar
• Mailhe M, Beaumont AL, Thy M, et al. Clinical characteristics of ambulatory and hospitalized patients with monkeypox virus infection: an observational cohort study. Clin Microbiol Infect. 2023;29(2):233–239.
   PubMed Web of Science ®Google Scholar
• Maronese CA, Beretta A, Avallone G, et al. Clinical, dermoscopic and histopathological findings in localized human monkeypox: a case from Northern Italy. Br J Dermatol. 2022;187(5):822–823.
   PubMed Web of Science ®Google Scholar
• Matias WR, Koshy JM, Nagami EH, et al. Tecovirimat for the treatment of human monkeypox: an initial series from Massachusetts, United States. Open Forum Infect Dis. 2022;9(8):ofac377.
   PubMed Web of Science ®Google Scholar
• McCollum AM, Nakazawa Y, Ndongala GM, et al. Human monkeypox in the kivus, a conflict region of the democratic republic of the Congo. Am J Trop Med Hyg. 2015;93(4):718–721.
   PubMed Web of Science ®Google Scholar
• Meduri E, Malcles A, Kecik M. Conjunctivitis with monkeypox virus positive conjunctival swabs. Ophthalmology. 2022;129(10):1095.
   PubMedGoogle Scholar
• Meyer H, Perrichot M, Stemmler M, et al. Outbreaks of disease suspected of being due to human monkeypox virus infection in the democratic republic of Congo in 2001. J Clin Microbiol. 2002;40(8):2919–2921.
   PubMed Web of Science ®Google Scholar
• Mileto D, Riva A, Cutrera M, et al. New challenges in human monkeypox outside Africa: a review and case report from Italy. Travel Med Infect Dis. 2022;49:102386.
   PubMed Web of Science ®Google Scholar
• Miura F, van Ewijk CE, Backer JA, et al. Estimated incubation period for monkeypox cases confirmed in The Netherlands, May 2022. Euro Surveill. 2022;27(24):2200448.
   PubMedGoogle Scholar
• Moschese D, Pozza G, Giacomelli A, et al. Natural history of human monkeypox in individuals attending a sexual health clinic in Milan, Italy. J Infect. 2023;86(1):e18–e20.
   PubMed Web of Science ®Google Scholar
• Noe S, Zange S, Seilmaier M, et al. Clinical and virological features of first human monkeypox cases in Germany. Infection. 2023;51(1):265–270.
   Google Scholar
• Ogoina D, Iroezindu M, James HI, et al. Clinical course and outcome of human monkeypox in Nigeria. Clin Infect Dis. 2020;71(8):e210–e214.
   PubMed Web of Science ®Google Scholar
• Oprea C, Ianache I, Piscu S, et al. First report of monkeypox in a patient living with HIV from Romania. Travel Med Infect Dis. 2022;49:102395.
   PubMed Web of Science ®Google Scholar
• Ortiz-Martinez Y, Rodriguez-Morales AJ, Franco-Paredes C, et al. Monkeypox – a description of the clinical progression of skin lesions: a case report from Colorado, USA. Ther Adv Infect Dis. 2022;9:20499361221117726.
   Web of Science ®Google Scholar
• Orviz E, Negredo A, Ayerdi O, et al. Monkeypox outbreak in Madrid (Spain): clinical and virological aspects. J Infect. 2022;85(4):412–417.
   PubMed Web of Science ®Google Scholar
• Paparizos V, Nicolaidou E, Tryfinopoulou K, et al. Monkeypox virus infection: first reported case in Greece in a patient with a genital rash. J Eur Acad Dermatol Venereol. 2023;37(3):e350–e351.
   PubMed Web of Science ®Google Scholar
• Patel A, Bilinska J, Tam JCH, et al. Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series. BMJ. 2022;378:e072410.
   PubMed Web of Science ®Google Scholar
• Peiro-Mestres A, Fuertes I, Camprubi-Ferrer D, et al. Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022. Euro Surveill. 2022;27(28):2200503.
   PubMedGoogle Scholar
• Pembi E, Awang S, Salaudeen SO, et al. First confirmed case of monkeypox in Adamawa state, Nigeria: a clinico-epidemiological case report. Pan Afr Med J. 2022;42:38.
   PubMed Web of Science ®Google Scholar
• Perez Duque M, Ribeiro S, Martins JV, et al. Ongoing monkeypox virus outbreak, Portugal, 29 April to 23 May 2022. Eurosurveillance. 2022;27(22):2200424.
   Web of Science ®Google Scholar
• Pfafflin F, Wendisch D, Scherer R, et al. Monkeypox in-patients with severe anal pain. Infection. 2023;51(2):483–487.
   PubMed Web of Science ®Google Scholar
• Philpott D, Hughes CM, Alroy KA, et al. Epidemiologic and clinical characteristics of monkeypox Cases – United States, May 17-July 22, 2022. MMWR Morb Mortal Wkly Rep. 2022;71(32):1018–1022.
   PubMed Web of Science ®Google Scholar
• Pipito L, Cascio A. Monkeypox virus infection and creatine phosphokinase increase: a case from Italy. Travel Med Infect Dis. 2022;50:102412.
   PubMed Web of Science ®Google Scholar
• Pittman PR, Martin JW, Kingebeni PM, et al. Clinical characterization of human monkeypox infections in the Democratic Republic of the Congo. PLoS Negl Trop Dis. 2023;17(4):e0010384.
   Google Scholar
• Portela-Dias J, Sereno S, Falcao-Reis I, et al. Monkeypox infection with localized genital lesions in women. Am J Obstet Gynecol. 2022;227(6):906.
   PubMed Web of Science ®Google Scholar
• Quattri E, Avallone G, Maronese CA, et al. Unilesional monkeypox: a report of two cases from Italy. Travel Med Infect Dis. 2022;49:102424.
   PubMed Web of Science ®Google Scholar
• Raccagni AR, Candela C, Mileto D, et al. Monkeypox infection among men who have sex with men: PCR testing on seminal fluids. J Infect. 2022;85(5):573–607.
   PubMed Web of Science ®Google Scholar
• Rimoin AW, Kisalu N, Kebela-Ilunga B, et al. Endemic human monkeypox, democratic republic of Congo, 2001–2004. Emerg Infect Dis. 2007;13(6):934–937.
   PubMed Web of Science ®Google Scholar
• Rimoin AW, Mulembakani PM, Johnston SC, et al. Major increase in human monkeypox incidence 30 years after smallpox vaccination campaigns cease in the democratic republic of Congo. Proc Natl Acad Sci U S A. 2010;107(37):16262–16267.
   PubMed Web of Science ®Google Scholar
• Sejvar JJ, Chowdary Y, Schomogyi M, et al. Human monkeypox infection: a family cluster in the midwestern United States. J Infect Dis. 2004;190(10):1833–1840.
   PubMed Web of Science ®Google Scholar
• Sukhdeo SS, Aldhaheri K, Lam PW, et al. A case of human monkeypox in Canada. CMAJ. 2022;194(29):E1031–E1035.
   PubMed Web of Science ®Google Scholar
• Tarín-Vicente EJ, Alemany A, Agud-Dios M, et al. Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study. Lancet. 2022;400(10353):661–669.
   PubMed Web of Science ®Google Scholar
• Torster L, Tegtmeyer J, Kott J, et al. Localized monkeypox infestation in MSM on pre-exposure prophylaxis. J Eur Acad Dermatol Venereol. 2023;37(3):e366–e367.
   PubMed Web of Science ®Google Scholar
• Turco M, Mancuso FR, Pisano L. A monkeypox virus infection mimicking primary syphilis. Br J Dermatol. 2022;187(6):e194–e195.
   PubMed Web of Science ®Google Scholar
• Tutu van Furth AM, van der Kuip M, van Els AL, et al. Paediatric monkeypox patient with unknown source of infection, The Netherlands, June 2022. Euro Surveill. 2022;27(29):2200552.
   PubMedGoogle Scholar
• Vallee A, Farfour E, Zucman D. Monkeypox virus: a novel sexually transmitted disease? A case report from France. Travel Med Infect Dis. 2022;49:102394.
   PubMed Web of Science ®Google Scholar
• Vaughan A, Aarons E, Astbury J, et al. Two cases of monkeypox imported to the United Kingdom, September 2018. Eurosurveillance. 2018;23(38):2–6.
   Web of Science ®Google Scholar
• Vivancos R, Anderson C, Blomquist P, et al. Community transmission of monkeypox in the United Kingdom, April to May 2022. Euro Surveill. 2022;27(22):2200422.
   PubMedGoogle Scholar
• Vusirikala A, Charles H, Balasegaram S, et al. Epidemiology of early monkeypox virus transmission in sexual networks of gay and bisexual men, England, 2022. Emerg Infect Dis. 2022;28(10):2082–2086.
   PubMed Web of Science ®Google Scholar
• Whitehouse ER, Bonwitt J, Hughes CM, et al. Clinical and epidemiological findings from enhanced monkeypox surveillance in Tshuapa Province, Democratic Republic of the Congo during 2011–2015. J Infect Dis. 2021;223(11):1870–1878.
   PubMed Web of Science ®Google Scholar
• Yadav PD, Reghukumar A, Sahay RR, et al. First two cases of monkeypox virus infection in travellers returned from UAE to India, July 2022. J Infect. 2022;85(5):e145–e148.
   PubMed Web of Science ®Google Scholar
• Zlamal M, Bartovska Z, Burantova A, et al. Monkeypox and herpes simplex virus type 2 coinfection: case report of perianal lesions in HIV-positive patient. Sexual Trans Dis. 2022;49(11):769–770.
   PubMed Web of Science ®Google Scholar
• Reveille JD, Williams FM. Rheumatologic complications of HIV infection. Best Pract Res Clin Rheumatol. 2006;20(6):1159–1179.
   PubMed Web of Science ®Google Scholar
• Farhadian S, Patel P, Spudich S. Neurological complications of HIV infection. Curr Infect Dis Rep. 2017;19(12):50.
   PubMed Web of Science ®Google Scholar
• Patel UK, Malik P, Li YJ, et al. Stroke and HIV-associated neurological complications: a retrospective nationwide study. J Med Virol. 2021;93(8):4915–4929.
   PubMed Web of Science ®Google Scholar
• Nishiura H. Early efforts in modeling the incubation period of infectious diseases with an acute course of illness. Emerg Themes Epidemiol. 2007;4:2.
   PubMedGoogle Scholar
• Reynolds MG, Yorita KL, Kuehnert MJ, et al. Clinical manifestations of human monkeypox influenced by route of infection. J Infect Dis. 2006;194(6):773–780.
   PubMed Web of Science ®Google Scholar
• Barker TH, Migliavaca CB, Stein C, et al. Conducting proportional meta-analysis in different types of systematic reviews: a guide for synthesisers of evidence. BMC Med Res Methodol. 2021;21(1):189.
   PubMed Web of Science ®Google Scholar
• Benites-Zapata VA, Ulloque-Badaracco JR, Alarcon-Braga EA, et al. Clinical features, hospitalisation and deaths associated with monkeypox: a systematic review and meta-analysis. Ann Clin Microbiol Antimicrob. 2022;21(1):36.
   PubMed Web of Science ®Google Scholar
• Bragazzi NL, Kong JD, Mahroum N, et al. Epidemiological trends and clinical features of the ongoing monkeypox epidemic: a preliminary pooled data analysis and literature review. J Med Virol. 2023;95(1):e27931.
   PubMed Web of Science ®Google Scholar