Investigation of frequent somatic mutations of MTND5 gene in gastric cancer cell lines and tissues

References

• Anderson S, Bankier AT, Barrell BG, de Bruijn MH, Coulson AR, Drouin J, Eperon IC, Nierlich DP, Roe BA, Sanger F, et al. 1981. Sequence and organization of the human mitochondrial genome. Nature. 290:457–465.
   PubMed Web of Science ®Google Scholar
• Andrews RM, Kubacka I, Chinnery PF, Lightowlers RN, Turnbull DM, Howell N. 1999. Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA. Nat Genet. 23:147.
   PubMed Web of Science ®Google Scholar
• Bai RK, Leal SM, Covarrubias D, Liu A, Wong LJ. 2007. Risk mitochondrial genetic background modifies breast cancer. Cancer Res. 67:4687–4694.
   PubMed Web of Science ®Google Scholar
• Bussard KM, Siracusa LD. 2017. Understanding mitochondrial polymorphisms in cancer. Cancer Res. 77:6051–6059.
   PubMed Web of Science ®Google Scholar
• Chatterjee A, Mambo E, Sidransky D. 2006. Mitochondrial DNA mutations in human cancer. Oncogene. 25:4663–4674.
   PubMed Web of Science ®Google Scholar
• Chen WQ, Zheng RS, Zhang SW, Li N, Zhao P, Li GL, Wu LY, He J. 2013. Report of incidence and mortality in china cancer registries,2009. Chin J Cancer Res. 25:10–21.
   PubMed Web of Science ®Google Scholar
• Connolly BS, Feigenbaum AS, Robinson BH, Dipchand AI, Simon DK, Tarnopolsky MA. 2010. MELAS syndrome, cardiomyopathy, rhabdomyolysis, and autism associated with the A3260G mitochondrial DNA mutation. Biochem Biophys Res Commun. 402:443–447.
   PubMed Web of Science ®Google Scholar
• Coxhead J, Kurzawa-Akanbi M, Hussain R, Pyle A, Chinnery P, Hudson G. 2016. Somatic mtDNA variation is an important component of Parkinson’s disease. Neurobiol Aging. 38:217.e1–e217.e6.
   Web of Science ®Google Scholar
• Croteau DL, Bohr VA. 1997. Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells. J Biol Chem. 272:25409–25412.
   PubMed Web of Science ®Google Scholar
• Czarnecka AM, Krawczyk T, Zdrozny M, Lubiński J, Arnold RS, Kukwa W, Scińska A, Golik P, Bartnik E, Petros JA. 2010. Mitochondrial NADH-dehydrogenase subunit 3 (ND3) polymorphism (A10398G) and sporadic breast cancer in Poland. Breast Cancer Res Treatment. 121:511–518.
   PubMed Web of Science ®Google Scholar
• Deans C, Yeo MS, Soe MY, Shabbir A, Ti TK, So JB. 2011. Cancer of the gastric cardia is rising in incidence in an Asian population and is associated with adverse outcome. World J Surg. 35:617–624.
   PubMed Web of Science ®Google Scholar
• Dhillon VS, Fenech M. 2014. Mutations that affect mitochondrial functions and their association with neurodegenerative diseases. Mutat Res Rev Mutat Res. 759:1–13.
   PubMed Web of Science ®Google Scholar
• Eckenweiler M, Catarino CB, Gallenmueller C, Klopstock T, Lagrèze WA, Korinthenberg R, Kirschner J. 2015. Mitochondrial DNA mutation 14487T > C manifesting as Leber's hereditary optic neuropathy. J Neurol. 262:2776–2779.
   PubMed Web of Science ®Google Scholar
• Galluzzi L, Kepp O, Trojel-Hansen C, Kroemer G. 2012. Mitochondrial control of cellular life, stress, and death. Circ Res. 111:1198–1207.
   PubMed Web of Science ®Google Scholar
• Grzybowska-Szatkowska L, Ślaska B. 2014. Mitochondrial NADH dehydrogenase polymorphisms are associated with breast cancer in Poland. J Appl Genet. 55:173–181.
   PubMed Web of Science ®Google Scholar
• Gu SY, Chen CZ, Jiang XJ, Zhang ZZ. 2016. ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction underlie apoptosis induced by resveratrol and arsenic trioxide in A549 cells. Chem-Biol Interact. 245:100–109.
   PubMed Web of Science ®Google Scholar
• Gupta M, Madkaikar M, Rao VB, Mishra A, Govindaraj P, Thangaraj K, Ghosh K. 2013. Mitochondrial DNA variations in myelodysplastic syndrome. Ann Hematol. 92:871–876.
   PubMed Web of Science ®Google Scholar
• Holzerová E, Prokisch H. 2015. Mitochondria: much ado about nothing? How dangerous is reactive oxygen species production? Int J Biochem Cell Biol. 63:16–20.
   PubMed Web of Science ®Google Scholar
• Kim H, Komiyama T, Inomoto C, Kamiguchi H, Kajiwara H, Kobayashi H, Nakamura N, Terachi T. 2016. Mutations in the mitochondrial ND1 gene are associated with postoperative prognosis of localized renal cell carcinoma. IJMS. 17:2049.
   Web of Science ®Google Scholar
• Kim SH, Kim KY, Park SG, Yu SN, Kim YW, Nam HW, An HH, Kim YW, Ahn SC. 2017. Mitochondrial ROS activates ERK/autophagy pathway as a protected mechanism against deoxypodophyllotoxin-induced apoptosis. Oncotarget. 8:111581–111596.
   PubMedGoogle Scholar
• Kytövuori L, Lipponen J, Rusanen H, Komulainen T, Martikainen MH, Majamaa K. 2016. A novel mutation m.8561C > G in MT-ATP6/8 causing a mitochondrial syndrome with ataxia, peripheral neuropathy, diabetes mellitus, and hypergonadotropic hypogonadism. J Neurol. 263:2188–2195.
   PubMed Web of Science ®Google Scholar
• Lightowlers RN, Taylor RW, Turnbul DM. 2015. Mutations causing mitochondrial disease: what is new and what challenges remain? Science. 349:1494–1499.
   PubMed Web of Science ®Google Scholar
• Márquez-Jurado S, Díaz-Colunga J, das Neves RP, Martinez-Lorente A, Almazán F, Guantes R, Iborra FJ. 2018. Mitochondrial levels determine variability in cell death by modulating apoptotic gene expression. Nat Commun. 9:389.
   PubMed Web of Science ®Google Scholar
• McCann BJ, Tuppen HAL, Küsters B, Lammens M, Smeitink JAM, Taylor RW, Rodenburg RJ, Wortmann SB. 2015. A novel mitochondrial DNA m.7507A > G mutation is only pathogenic at high levels of heteroplasmy. Neuromuscul Disord. 25:262–267.
   PubMed Web of Science ®Google Scholar
• McLean MH, El-Omar EM. 2014. Genetics of gastric cancer. Nat Rev Gastroenterol Hepatol. 11:664–674.
   PubMed Web of Science ®Google Scholar
• Montiel-Sosa JF, Herrero MD, Munoz MdL, Aguirre-Campa LE, Pérez-Ramírez G, García-Ramírez R, Ruiz-Pesini E, Montoya J. 2013. Phylogenetic analysis of mitochondrial DNA in a patient with Kearns–Sayre syndrome containing a novel 7629-bp deletion. Mitochondr DNA. 24:420–431.
   PubMed Web of Science ®Google Scholar
• Mosquera-Miguel A, Álvarez-Iglesias V, Cerezo M, Lareu MV, Carracedo Á, Salas A. 2009. Testing the performance of mtSNP minisequencing in forensic samples. Forensic Sci Int Genet. 3:261–264.
   PubMed Web of Science ®Google Scholar
• Parr RL, Maki J, Reguly B, Dakubo GD, Aguirre A, Wittock R, Robinson K, Jakupciak JP, Thayer RE. 2006. The pseudo-mitochondrial genome influences mistakes in heteroplasmy interpretation. BMC Genomics. 7:185.
   PubMed Web of Science ®Google Scholar
• Ren Z, Luo HB, Song F, Wei W, Yang YY, Zhai XD, Chen XG, Hou YP. 2015. Developing a multiplex mtSNP assay for forensic application in Han Chinese based on mtDNA phylogeny and hotspot. Electrophoresis. 36:633–639.
   PubMed Web of Science ®Google Scholar
• Sena LA, Chandel NS. 2012. Physiological roles of mitochondrial reactive oxygen species. Mol Cell. 48:158–167.
   PubMed Web of Science ®Google Scholar
• Stefano GB, Kream RM. 2016. Mitochondrial DNA heteroplasmy in human health and disease. Biomed Rep. 4:259–262.
   PubMed Web of Science ®Google Scholar
• Thun MJ, DeLancey JO, Center MM, Jemal A, Ward EM. 2010. The global burden of cancer: priorities for prevention. Carcinogenesis. 31:100–110.
   PubMed Web of Science ®Google Scholar
• Todorov IN, Todorov GI. 2009. Multifactorial nature of high frequency of mitochondrial DNA mutations in somatic mammalian cells. Biochemistry (Mosc). 74:962–970.
   PubMed Web of Science ®Google Scholar
• van der Walt JM, Nicodemus KK, Martin ER, Scott WK, Nance MA, Watts RL, Hubble JP, Haines JL, Koller WC, Lyons K, et al. 2003. Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease. Am J Hum Genet. 72:804–811.
   PubMed Web of Science ®Google Scholar
• Wallace DC. 2012. Mitochondria and cancer. Nat Rev Cancer. 12:685–698.
   PubMed Web of Science ®Google Scholar
• Wang L, Bamlet WR, de Andrade M, Boardman LA, Cunningham JM, Thibodeau SN, Petersen GM. 2007. Mitochondrial genetic polymorphisms and pancreatic cancer risk. Cancer Epidemiol Biomarkers Prev. 16:1455–1459.
   PubMed Web of Science ®Google Scholar
• Williams Stephen B, Ye YQ, Huang MS, Chang DW, Kamat AM, Pu X, Dinney CP, Wu X. 2015. Mitochondrial DNA content as risk factor for bladder cancer and its association with mitochondrial DNA polymorphisms. Cancer Prev Res (Phila). 8:607–613.
   PubMed Web of Science ®Google Scholar
• Xu B, Li X, Du M, Zhou C, Fang H, Lyu J, Yang Y. 2017. Novel mutation of ND4 gene identified by targeted next-generation sequencing in patient with Leigh syndrome. J Hum Genet. 62:291–297.
   PubMed Web of Science ®Google Scholar
• Ye KX, Lu J, Ma F, Keinan A, Gu ZL. 2014. Extensive pathogenicity of mitochondrial heteroplasmy in healthy human individuals. PNAS. 111:10654–10659.
   PubMed Web of Science ®Google Scholar
• Zamzami N, Kroemer G. 2001. The mitochondrion in apoptosis: how Pandora's box opens. Nat Rev Mol Cell Biol. 2:67–71.
   PubMed Web of Science ®Google Scholar