126
Views
2
CrossRef citations to date
0
Altmetric
Article

Cytotoxic effect, apoptotic activity, hematological and histological alterations induced by green synthesized ZnO nanoparticles applying Hyssopus officinalis leaves

, , &
Pages 1560-1569 | Received 03 May 2020, Accepted 18 Oct 2020, Published online: 19 Nov 2020

References

  • Pujalté, I.; Passagne, I.; Brouillaud, B.; Tréguer, M.; Durand, E.; Ohayon-Courtès, C.; L’Azou, B. Cytotoxicity and Oxidative Stress Induced by Different Metallic Nanoparticles on Human Kidney Cells. Part. Fibre Toxicol. 2011, 8, 10. DOI: 10.1186/1743-8977-8-10.
  • Peng, X.-H.; Qian, X.; Mao, H.; Wang, A. Y.; Chen, Z. G.; Nie, S.; Shin, D. M. Targeted Magnetic Iron Oxide Nanoparticles for Tumor Imaging and Therapy. Int. J. Nanomedicine 2008, 3, 311–321. DOI: 10.2147/ijn.s2824.
  • Zhang, H.; Chen, B.; Jiang, H.; Wang, C.; Wang, H.; Wang, X. A Strategy for ZnO Nanorod Mediated Multi-Mode Cancer Treatment. Biomaterials 2011, 32, 1906–1914.
  • Mohammad, G. R. K. S.; Tabrizi, M. H.; Ardalan, T.; Yadamani, S.; Safavi, E. Green Synthesis of Zinc Oxide Nanoparticles and Evaluation of Anti-Angiogenesis, Anti-Inflammatory and Cytotoxicity Properties. J. Biosci. 2019, 44, 30.
  • Nagajyothi, P. C.; Cha, S. J.; Yang, I. J.; Sreekanth, T. V.; Kim, K. J.; Shin, H. M. Antioxidant and Anti-Inflammatory Activities of Zinc Oxide Nanoparticles Synthesized Using Polygala tenuifolia Root Extract. J. Photochem. Photobiol. B 2015, 146, 10–17. DOI: 10.1016/j.jphotobiol.2015.02.008.
  • Dufour, E. K.; Kumaravel, T.; Nohynek, G. J.; Kirkland, D.; Toutain, H. Clastogenicity, Photo-Clastogenicity or Pseudo-Photo-Clastogenicity: Genotoxic Effects of Zinc Oxide in the Dark, in Pre-Irradiated or Simultaneously Irradiated Chinese Hamster Ovary Cells. Mutat. Res. 2006, 607, 215–224. DOI: 10.1016/j.mrgentox.2006.04.015.
  • Hanley, C.; Layne, J.; Punnoose, A.; Reddy, K. M.; Coombs, I.; Coombs, A.; Feris, K.; Wingett, D. Preferential Killing of Cancer Cells and Activated Human T Cells Using ZnO Nanoparticles. Nanotechnology 2008, 19, 295103. DOI: 10.1088/0957-4484/19/29/295103.
  • Mahanta, S.; Prathap, S.; Ban, D. K.; Paul, S. Protein Functionalization of ZnO Nanostructure Exhibits Selective and Enhanced Toxicity to Breast Cancer Cells through Oxidative Stress-Based Cell Death Mechanism. J. Photochem. Photobiol. B 2017, 173, 376–388. DOI: 10.1016/j.jphotobiol.2017.06.015.
  • Gopala Krishna, P.; Paduvarahalli Ananthaswamy, P.; Yadavalli, T.; Bhangi Mutta, N.; Sannaiah, A.; Shivanna, Y. ZnO Nanopellets Have Selective Anticancer Activity. Mater. Sci. Eng. C Mater. Biol. Appl. 2016, 62, 919–926. DOI: 10.1016/j.msec.2016.02.039.
  • Ostrovsky, S.; Kazimirsky, G.; Gedanken, A.; Brodie, C. Selective Cytotoxic Effect of ZnO Nanoparticles on Glioma Cells. Nano Res. 2009, 2, 882–890.
  • Premanathan, M.; Karthikeyan, K.; Jeyasubramanian, K.; Manivannan, G. Selective Toxicity of ZnO Nanoparticles toward Gram-Positive Bacteria and Cancer Cells by Apoptosis through Lipid Peroxidation. Nanomed. Nanotechnol. Biol. Med. 2011, 7, 184–192.
  • Nel, A.; Xia, T.; Madler, L.; Li, N. Toxic Potential of Materials at the Nanolevel. Science 2006, 311, 622–627. DOI: 10.1126/science.1114397.
  • Reddy, K. M.; Feris, K.; Bell, J.; Wingett, D. G.; Hanley, C.; Punnoose, A. Selective Toxicity of Zinc Oxide Nanoparticles to Prokaryotic and Eukaryotic Systems. Appl. Phys. Lett. 2007, 90, 2139021–2139023. DOI: 10.1063/1.2742324.
  • Hanley, C.; Thurber, A.; Hanna, C.; Punnoose, A.; Zhang, J.; Wingett, D. G. The Influences of Cell Type and ZnO Nanoparticle Size on Immune Cell Cytotoxicity and Cytokine Induction. Nanoscale Res. Lett. 2009, 4, 1409–1420. DOI: 10.1007/s11671-009-9413-8.
  • AshaRani, P.; Low Kah Mun, G.; Hande, M. P.; Valiyaveettil, S. Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells. ACS Nano. 2009, 3, 279–290. DOI: 10.1021/nn800596w.
  • Ferrari, M. Cancer Nanotechnology: Opportunities and Challenges. Nat. Rev. Cancer 2005, 5, 161–171. DOI: 10.1038/nrc1566.
  • Boyle, P.; Levin, B. World Cancer Report 2008; IARC Press, International Agency for Research on Cancer, 2008.
  • Brahmer, J.; Reckamp, K. L.; Baas, P.; Crinò, L.; Eberhardt, W. E. E.; Poddubskaya, E.; Antonia, S.; Pluzanski, A.; Vokes, E. E.; Holgado, E.; et al. Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer. N. Engl. J. Med. 2015, 373, 123–135.
  • Köhler, D.; Dellweg, D. Polycythemia. Dtsch. Med. Wochenschr. 2010, 135, 2300–2303. 2010DOI: 10.1055/s-0030-1267515.
  • Chuang, H.-C.; Chuang, K.-J.; Chen, J.-K.; Hua, H.-E.; Shen, Y.-L.; Liao, W.-N.; Lee, C.-H.; Pan, C.-H.; Chen, K.-Y.; Lee, K.-Y.; et al. Pulmonary Pathobiology Induced by Zinc Oxide Nanoparticles in Mice: A 24-Hour and 28-Day Follow-Up Study. Toxicol. Appl. Pharmacol. 2017, 327, 13–22.
  • Kao, Y.-Y.; Chen, Y.-C.; Cheng, T.-J.; Chiung, Y.-M.; Liu, P.-S. Zinc Oxide Nanoparticles Interfere with Zinc Ion Homeostasis to Cause Cytotoxicity. Toxicol. Sci. 2012, 125, 462–472. DOI: 10.1093/toxsci/kfr319.
  • Magaye, R. R.; Yue, X.; Zou, B.; Shi, H.; Yu, H.; Liu, K.; Lin, X.; Xu, J.; Yang, C.; Wu, A.; et al. Acute Toxicity of Nickel Nanoparticles in Rats after Intravenous Injection. Int. J. Nanomedicine 2014, 9, 1393–1402. DOI: 10.2147/IJN.S56212.
  • Ahmed, S.; Saifullah, Ahmad, M.; Swami, B. L.; Ikram, S. Green Synthesis of Silver Nanoparticles Using Azadirachta indica Aqueous Leaf Extract. J. Radiat. Res. Appl. Sci. 2016, 9, 1–7.
  • Santhoshkumar, J.; Kumar, S. V.; Rajeshkumar, S. Synthesis of Zinc Oxide Nanoparticles Using Plant Leaf Extract against Urinary Tract Infection Pathogen. Resour-Effic. Technol. 2017, 3, 459–465.
  • Moshmann, T. Rapid Colorimetric Assay for Cellular Growth and Survival: Application to Proliferation and Cytotoxicity Assay. J. Immunol. Method 1983, 65, 55–63.
  • Supino, R. MTT Assays. In Vitro Toxicity Testing Protocols; Springer, 1995; pp. 137–149.
  • Safavi, E.; Homayouni-Tabrizi, M.; Karimi, E.; Rahimi Kalateh Shah Mohammad, G. Biosynthesis of Zinc Oxide Nanoparticles Using Anjbar (Root of Persicaria bistorta) Extract and Their Cytotoxic Effects on Human Breast Cancer Cell Line (MCF-7). IET Nanobiotechnol. 2019, 13, 736–741.
  • Shapiro, H. M. Practical Flow Cytometry; John Wiley & Sons, 2005.
  • Rahimi Kalateh Shah Mohammad, G.; Karimi, E.; Oskoueian, E.; Homayouni-Tabrizi, M. Anticancer Properties of Green-Synthesised Zinc Oxide Nanoparticles Using Hyssopus officinalis Extract on Prostate Carcinoma Cells and Its Effects on Testicular Damage and Spermatogenesis in Balb/C Mice. Andrologia 2020, 52, e13450.
  • Compton, M. M. A Biochemical Hallmark of Apoptosis: Internucleosomal Degradation of the Genome. Cancer Metastasis Rev. 1992, 11, 105–119. DOI: 10.1007/BF00048058.
  • Hackenberg, S.; Zimmermann, F.-Z.; Scherzed, A.; Friehs, G.; Froelich, K.; Ginzkey, C.; Koehler, C.; Burghartz, M.; Hagen, R.; Kleinsasser, N.; et al. Repetitive Exposure to Zinc Oxide Nanoparticles Induces DNA Damage in Human Nasal Mucosa Mini Organ Cultures. Environ. Mol. Mutagen. 2011, 52, 582–589. DOI: 10.1002/em.20661.
  • Guo, H.; Qian, H.; Idris, N. M.; Zhang, Y. Singlet Oxygen-Induced Apoptosis of Cancer Cells Using Upconversion Fluorescent Nanoparticles as a Carrier of Photosensitizer. Nanomedicine 2010, 6, 486–495. DOI: 10.1016/j.nano.2009.11.004.
  • Sasidharan, A.; Chandran, P.; Menon, D.; Raman, S.; Nair, S.; Koyakutty, M. Rapid Dissolution of ZnO Nanocrystals in Acidic Cancer Microenvironment Leading to Preferential Apoptosis. Nanoscale 2011, 3, 3657–3669. DOI: 10.1039/c1nr10272a.
  • Gupta, J.; Bhargava, P.; Bahadur, D. Fluorescent ZnO for Imaging and Induction of DNA Fragmentation and ROS-Mediated Apoptosis in Cancer Cells. J. Mater. Chem. B 2015, 3, 1968–1978.
  • Li, J.-H.; Liu, X.-R.; Zhang, Y.; Tian, F.-F.; Zhao, G.-Y.; Yu, Q.-L.-Y.; Jiang, F.-L.; Liu, Y. Toxicity of Nano Zinc Oxide to Mitochondria. Toxicol. Res. 2012, 1, 137–144.
  • Choi, D. W.; Koh, J. Y. Zinc and Brain Injury. Annu. Rev. Neurosci. 1998, 21, 347–375. DOI: 10.1146/annurev.neuro.21.1.347.
  • Foldbjerg, R.; Dang, D. A.; Autrup, H. Cytotoxicity and Genotoxicity of Silver Nanoparticles in the Human Lung Cancer Cell Line, A549. Arch. Toxicol. 2011, 85, 743–750. DOI: 10.1007/s00204-010-0545-5.
  • Akhtar, M. J.; Ahamed, M.; Kumar, S.; Khan, M. M.; Ahmad, J.; Alrokayan, S. A. Zinc Oxide Nanoparticles Selectively Induce Apoptosis in Human Cancer Cells through Reactive Oxygen Species. Int. J. Nanomedicine 2012, 7, 845–857. DOI: 10.2147/IJN.S29129.
  • Li, B.; Weng, Q.; Liu, Z.; Shen, M.; Zhang, J.; Wu, W.; Liu, H. Selection of Antioxidants against Ovarian Oxidative Stress in Mouse Model. J. Biochem. Mol. Toxicol. 2017, 31, e21997.
  • Salganik, R. I. The Benefits and Hazards of Antioxidants: Controlling Apoptosis and Other Protective Mechanisms in Cancer Patients and the Human Population. J. Am. Coll. Nutr. 2001, 20, 464S–472S. DOI: 10.1080/07315724.2001.10719185.
  • Dhanasekaran, A.; Kotamraju, S.; Kalivendi, S. V.; Matsunaga, T.; Shang, T.; Keszler, A.; Joseph, J.; Kalyanaraman, B. Supplementation of Endothelial Cells with Mitochondria-Targeted Antioxidants Inhibit Peroxide-Induced Mitochondrial Iron Uptake, Oxidative Damage, and Apoptosis. J. Biol. Chem. 2004, 279, 37575–37587.
  • Coussens, L. M.; Werb, Z. Inflammation and Cancer. Nature 2002, 420, 860–867. DOI: 10.1038/nature01322.
  • Kodavanti, U. P.; Schladweiler, M. C.; Gilmour, P. S.; Wallenborn, J. G.; Mandavilli, B. S.; Ledbetter, A. D.; Christiani, D. C.; Runge, M. S.; Karoly, E. D.; Costa, D. L.; et al. The Role of Particulate Matter-Associated Zinc in Cardiac Injury in Rats. Environ. Health Perspect. 2008, 116, 13–20. DOI: 10.1289/ehp.10379.
  • Park, S. J.; Park, Y. C.; Lee, S. W.; Jeong, M. S.; Yu, K.-N.; Jung, H.; Lee, J.-K.; Kim, J. S.; Cho, M.-H. Comparing the Toxic Mechanism of Synthesized Zinc Oxide Nanomaterials by Physicochemical Characterization and Reactive Oxygen Species Properties. Toxicol. Lett. 2011, 207, 197–203. DOI: 10.1016/j.toxlet.2011.09.011.
  • Lacroix, E. M.; Mehnert, R. The US National Library of Medicine in the 21st Century: Expanding Collections, Nontraditional Formats, New Audiences. Health Info. Libr. J. 2002, 19, 126–132. DOI: 10.1046/j.1471-1842.2002.00382.x.
  • Sangeetha, G.; Rajeshwari, S.; Venckatesh, R. Green Synthesis of Zinc Oxide Nanoparticles by Aloe Barbadensis Miller Leaf Extract: Structure and Optical Properties. Mater. Res. Bull. 2011, 46, 2560–2566.
  • Pavlisa, G.; Vrbanic, V.; Kusec, V.; Jaksic, B. Erythropoietin Response after Correction of Severe Hypoxaemia Due to Acute Respiratory Failure in Chronic Obstructive Pulmonary Disease Patients. Clin. Sci. 2004, 106, 43–51. DOI: 10.1042/CS20030165.
  • Yu, B. P. Cellular Defenses against Damage from Reactive Oxygen Species. Physiol. Rev. 1994, 74, 139–162. DOI: 10.1152/physrev.1994.74.1.139.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.