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Canadian Journal of Pain
Revue canadienne de la douleur
Volume 6, 2022 - Issue 1
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Research Article

Prevalence of cannabis use for pain management in Quebec: A post-legalization estimate among generations living with chronic pain

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Pages 65-77 | Received 30 Nov 2021, Accepted 05 Mar 2022, Published online: 03 Jun 2022

References

  • Rotermann M, Pagé -M-M. Prevalence and correlates of non-medical only compared to self-defined medical and non-medical cannabis use, Canada, 2015. Health Reports. 2018;29:3–13.
  • Lucas P, Walsh Z. Medical cannabis access, use, and substitution for prescription opioids and other substances: a survey of authorized medical cannabis patients. Int J Drug Policy. 2017;42:30–35. doi:10.1016/j.drugpo.2017.01.011.
  • Meng H, Page MG, Ajrawat P, Deshpande A, Samman B, Dominicis M, Ladha KS, Fiorellino J, Huang A, Kotteeswaran Y, et al. Résultats rapportés par les patients consommant du cannabis médical: une étude observationnelle longitudinale prospective chez des patients souffrant de douleur chronique. Can J Anaesth. 2021;68(5):633–44. doi:10.1007/s12630-020-01903-1.
  • Gorvernment of Canada. Cannabis Legalization and Regulation. 2021. [accessed 2021 Sept 9]. https://www.justice.gc.ca/eng/cj-jp/cannabis/.
  • Statistics Canada. Canadian Cannabis Survey 2020: summary; 2020. [accessed 2021 Aug 31]. https://www.canada.ca/en/health-canada/services/drugs-medication/cannabis/research-data/canadian-cannabis-survey-2020-summary.html#a2.
  • Canadian Pain Task Force. Chronic pain in Canada: laying a foundation for action. Ottawa, Ontario: Health Canada; 2019.
  • Wang L, Hong PJ, May C, Rehman Y, Oparin Y, Hong CJ, Hong BY, AminiLari M, Gallo L, Kaushal A, et al. Medical cannabis or cannabinoids for chronic non-cancer and cancer related pain: a systematic review and meta-analysis of randomised clinical trials. BMJ. 2021;374(1034):1–15.
  • IASP Presidential Task Force on Cannabis Cannabinoid Analgesia. International Association for the Study of Pain Presidential Task Force on Cannabis and Cannabinoid Analgesia position statement. PAIN. 2021;162(Suppl 1):S1–S2. doi:10.1097/j.pain.0000000000002265.
  • Rice AS, Belton J, Nielsen LA. Presenting the outputs of the IASP presidential task force on cannabis and cannabinoid analgesia. Pain. 2021;162(Suppl 1):S3–S4. doi:10.1097/j.pain.0000000000002210.
  • Fitzcharles M-A, Niaki OZ, Hauser W, Hazlewood G. Canadian rheumatology association. position statement: a pragmatic approach for medical cannabis and patients with rheumatic diseases. J Rheumatol. 2019;46(5):532–38. doi:10.3899/jrheum.181120.
  • NICE. Cannabis-based medicinal products: NICE Guideline. London (UK): National Institute for Clinical Excellence (NICE); 2019. [accessed 2022 Apr 22]. https://www.nice.org.uk/guidance/ng144.
  • Moore RA, Fisher E, Finn DP, Finnerup NB, Gilron I, Haroutounian S, Krane E, Rice AS, Rowbotham M, Wallace M. Cannabinoids, cannabis, and cannabis-based medicines for pain management: an overview of systematic reviews. Pain. 2020;162:S67–S79.
  • Schilling JM, Hughes CG, Wallace MS, Sexton M, Backonja M, Moeller-Bertram T. Cannabidiol as a treatment for chronic pain: a survey of patients’ perspectives and attitudes. J Pain Res. 2021;14:1241–50. doi:10.2147/JPR.S278718.
  • Furrer D, Kroger E, Marcotte M, Jauvin N, Belanger R, Ware M, Foldes-Busque G, Aubin M, Pluye P, Dionne CE. Cannabis against chronic musculoskeletal pain: a scoping review on users and their perceptions. J Cannabis Res. 2021;3(1):41. doi:10.1186/s42238-021-00096-8.
  • Busse JW, Vankrunkelsven P, Zeng L, Heen AF, Merglen A, Campbell F, Granan L-P, Aertgeerts B, Buchbinder R, Coen M, et al. Medical cannabis or cannabinoids for chronic pain: a clinical practice guideline. BMJ. 2021;374:2040. doi:10.1136/bmj.n2040.
  • Ware MA, Doyle CR, Woods R, Lynch ME, Clark AJ. Cannabis use for chronic non-cancer pain: results of a prospective survey. Pain. 2003;102(1):211–16. doi:10.1016/s0304-3959(02)00400-1.
  • Ste-Marie PA, Shir Y, Rampakakis E, Sampalis JS, Karellis A, Cohen M, Starr M, Ware MA, Fitzcharles M-A. Survey of herbal cannabis (marijuana) use in rheumatology clinic attenders with a rheumatologist confirmed diagnosis. Pain. 2016;157(12):2792–97. doi:10.1097/j.pain.0000000000000706.
  • Fitzcharles MA, Rampakakis E, Sampalis J, Shir Y, Cohen M, Starr M, Häuser W. Medical Cannabis Use by Rheumatology Patients Following Recreational Legalization: a Prospective Observational Study of 1000 Patients in Canada. ACR Open Rheumatol. 2020;2(5):286–93. doi:10.1002/acr2.11138.
  • Hasin DS, Shmulewitz D, Sarvet AL. Time trends in US cannabis use and cannabis use disorders overall and by sociodemographic subgroups: a narrative review and new findings. Am J Drug Alcohol Abuse. 2019;45(6):623–43. doi:10.1080/00952990.2019.1569668.
  • Hamilton HA, Brands B, Ialomiteanu AR, Mann RE. Therapeutic use of cannabis: prevalence and characteristics among adults in Ontario, Canada. Can J Public Health. 2017;108(3):e282–e7. doi:10.17269/CJPH.108.6130.
  • Lacasse A, Gagnon V, Nguena Nguefack HL, Gosselin M, Pagé MG, Blais L, Guénette L. Chronic pain patients’ willingness to share personal identifiers on the web for the linkage of medico-administrative claims and patient-reported data: the chronic pain treatment cohort. Pharmacoepidemiol Drug Saf. 2021;30(8):1012–26. doi:10.1002/pds.5255.
  • Treede RD, Rief W, Barke A, Aziz Q, Bennett MI, Benoliel R, Cohen M, Evers S, Finnerup NB, First MB, et al. Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11). Pain. 2019;160(1):19–27. doi:10.1097/j.pain.0000000000001384.
  • CPN. Chronic Pain Network Annual Report 2016/2017. Hamilton (ON): Chronic Pain Network; 2017. [accessed 2022 Apr 22]. https://cpn.mcmaster.ca/docs/default-source/annual-reports/2017-annual-report-en.pdf?sfvrsn=2d511708_4.
  • Turk DC, Dworkin RH, Allen RR, Bellamy N, Brandenburg N, Carr DB, Cleeland C, Dionne R, Farrar JT, Galer BS, et al. Core outcome domains for chronic pain clinical trials: IMMPACT recommendations. Pain. 2003;106(3):337–45. doi:10.1016/j.pain.2003.08.001.
  • Dworkin RH, Turk DC, Farrar JT, Haythornthwaite JA, Jensen MP, Katz NP, Kerns RD, Stucki G, Allen RR, Bellamy N, et al. Core outcome measures for chronic pain clinical trials: IMMPACT recommendations. Pain. 2005;113(1):9–19. doi:10.1016/j.pain.2004.09.012.
  • Lacasse A, Roy JS, Parent AJ, Noushi N, Odenigbo C, Page G, Beaudet N, Choiniere M, Stone LS, Ware MA, et al. The Canadian minimum dataset for chronic low back pain research: a cross-cultural adaptation of the National. Institutes of Health Task Force Research Standards. CMAJ Open. 2017;5(1):E237–E48.
  • Choiniere M, Ware MA, Page MG, Lacasse A, Lanctot H, Beaudet N, Boulanger A, Bourgault P, Cloutier C, Coupal L, et al. Development and Implementation of a Registry of Patients Attending Multidisciplinary Pain Treatment Clinics: the Quebec Pain Registry. Pain Res Manag. 2017;2017(8123812):1–16. doi:10.1155/2017/8123812.
  • Jones MK, Calzavara L, Allman D, Worthington CA, Tyndall M, Iveniuk J. A Comparison of Web and Telephone Responses From a National HIV and AIDS Survey. JMIR Public Health Surveill. 2016;2(2):e37. doi:10.2196/publichealth.5184.
  • Boulanger A, Clark AJ, Squire P, Cui E, Horbay GL. Chronic pain in Canada: have we improved our management of chronic noncancer pain? Pain Res Manag. 2007;12(1):39–47. doi:10.1155/2007/762180.
  • Moulin DE, Clark AJ, Speechley M, Morley-Forster PK. Chronic pain in Canada–prevalence, treatment, impact and the role of opioid analgesia. Pain Res Manag. 2002;7(4):179–84. doi:10.1155/2002/323085.
  • Schopflocher D, Taenzer P, Jovey R. The prevalence of chronic pain in Canada. Pain Res Manag. 2011;16(6):445–50. doi:10.1155/2011/876306.
  • Toth C, Lander J, Wiebe S. The prevalence and impact of chronic pain with neuropathic pain symptoms in the general population. Pain Med. 2009;10(5):918–29. doi:10.1111/j.1526-4637.2009.00655.x.
  • Bouhassira D, Lanteri-Minet M, Attal N, Laurent B, Touboul C. Prevalence of chronic pain with neuropathic characteristics in the general population. Pain. 2008;136(3):380–87. doi:10.1016/j.pain.2007.08.013.
  • Breivik H, Collett B, Ventafridda V, Cohen R, Gallacher D. Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment. Eur J Pain. 2006;10(4):287–333. doi:10.1016/j.ejpain.2005.06.009.
  • CEFRIO. L’usage des médias sociaux au Québec. Enquête NETendances. 2018;9(5):1–18.
  • Marshall K. Utilisation de l’ordinateur au travail. L’emploi et le revenu en perspective. L’édition en ligne. 2001;2(5):8–15.
  • Loikas D, Wettermark B, von Euler M, Bergman U, Schenck-Gustafsson K. Differences in drug utilisation between men and women: a cross-sectional analysis of all dispensed drugs in Sweden. BMJ open. 2013;3(5). doi:10.1136/bmjopen-2012-002378.
  • Statistics Canada. The Canadian Populationin in 2011: Age and Sex. Age and Sex, 2011 Census. Ottawa, Ontario, Canada: Statistics Canada; 2012. [accessed 2022 Apr 22]. https://www12.statcan.gc.ca/census-recensement/2011/as-sa/98-311-x/98-311-x2011001-eng.pdf.
  • Heidari S, Babor TF, De Castro P, Tort S, Curno M. Sex and Gender Equity in Research: rationale for the SAGER guidelines and recommended use. Res Integr Peer Rev. 2016;1(1):2. doi:10.1186/s41073-016-0007-6.
  • Sourial N, Vedel I, Le Berre M, Schuster T. Testing group differences for confounder selection in nonrandomized studies: flawed practice. Can Med Assoc J. 2019;191(43):E1189–E93. doi:10.1503/cmaj.190085.
  • Katz MH. Multivariable Analysis: a Practical Guide for Clinicians and Public Health Researchers. 3rd ed. Cambridge: Cambridge University Press; 2011.
  • Vatcheva KP, Lee M, McCormick JB, Rahbar MH. Multicollinearity in Regression Analyses Conducted in Epidemiologic Studies. Epidemiology. 2016;6(2). doi:10.4172/2161-1165.1000227.
  • Davies HT, Crombie IK, Tavakoli M. When can odds ratios mislead? BMJ. 1998;316(7136):989–91. doi:10.1136/bmj.316.7136.989.
  • Statistics Canada. Table 1310-038301: prevalence of cannabis use in the past three months Government of Canada; 2021. [accessed 2022 Apr 22]. https://www150.statcan.gc.ca/t1/tbl1/en/tv.action?pid=1310038301.
  • Leung J, Chan G, Stjepanovic D, Chung JYC, Hall W, Hammond D. Prevalence and self-reported reasons of cannabis use for medical purposes in USA and Canada. Psychopharmacology (Berl). 2022. doi:10.1007/s00213-021-06047-8.
  • Fitzcharles MA, Rampakakis E, Sampalis J, Shir Y, Cohen M, Starr M, Häuser W. Use of medical cannabis by patients with fibromyalgia in Canada after cannabis legalisation: a cross-sectional study. Clin Exp Rheumatol. 2021;39 Suppl 130:115–19.
  • Lacasse A, Page MG, Dassieu L, Sourial N, Janelle-Montcalm A, Dorais M, Nguena Nguefack HL, Godbout-Parent M, Hudspith M, Moor G, et al. Impact of the COVID-19 pandemic on the pharmacological, physical, and psychological treatments of pain: findings from the Chronic Pain & COVID-19 Pan-Canadian Study. Pain Rep. 2021;6(1):e891. doi:10.1097/PR9.0000000000000891.
  • Salloum NC, Krauss MJ, Agrawal A, Bierut LJ, Grucza RA. A reciprocal effects analysis of cannabis use and perceptions of risk. Addiction. 2018;113(6):1077–85. doi:10.1111/add.14174.
  • Porath-Waller AJ, Brown JE, Frigon AP, Clark H What Canadian Youth Think About Cannabis: technical Report. Ottawa, Ontario: Canadian Centre on Substance Use and Addiction (CCSA); 2013. [accessed 2022 Apr 22]. https://www.ccsa.ca/sites/default/files/2019-05/CCSA-What-Canadian-Youth-Think-about-Cannabis-2013-en.pdf.
  • Boehnke KF, Litinas E, Worthing B, Conine L, Kruger DJ. Communication between healthcare providers and medical cannabis patients regarding referral and medication substitution. J Cannabis Res. 2021;3(1):2. doi:10.1186/s42238-021-00058-0.
  • Grootendorst P, Ranjithan R. Pharmacists should counsel users of medical cannabis, but should they be dispensing it? Canadian Pharmacists Journal / Revue Des Pharmaciens du Canada. 2019;152(1):10–13. doi:10.1177/1715163518814273.
  • CPhA. CPhA position statement: medical marijuana ottawa: Canadian Pharmacists Association; 2016. [accessed 2022 Apr 22]. https://www.pharmacists.ca/cpha-ca/assets/File/cpha-on-the-issues/CPhAPosition_MedicalMarijuana.pdf.
  • Dattani S, Mohr H. Pharmacists’ role in cannabis dispensing and counselling. Can Pharm J. 2019;152(1):14. doi:10.1177/1715163518813314.
  • Reisfield GM, Wasan AD, Jamison RN. The prevalence and significance of cannabis use in patients prescribed chronic opioid therapy: a review of the extant literature. Pain Med. 2009;10(8):1434–41. doi:10.1111/j.1526-4637.2009.00726.x.
  • Asselin A, Beauparlant Lamarre O, Chamberland R, Mc Neil S-J, É D, Arsene Zongo A. A description of self-medication with cannabis among adults with legal access to cannabis. Research Square. 2021. [accessed 2022 Apr 22]. https://doi.org/10.21203/rs.3.rs-528768/v1.
  • Warf B. High points: an historical geography of cannabis. Geog Rev. 2014;104(4):414–38. doi:10.1111/j.1931-0846.2014.12038.x.
  • Orhurhu V, Urits I, Olusunmade M, Olayinka A, Orhurhu MS, Uwandu C, Aner M, Ogunsola S, Akpala L, Hirji S. cannabis use in hospitalized patients with chronic pain. Adv Ther. 2020;37(8):3571–3583.
  • Lowry DE, Corsi DJ. Trends and correlates of cannabis use in Canada: a repeated cross-sectional analysis of national surveys from 2004 to 2017. CMAJ Open. 2020;8(3):E487–E95. doi:10.9778/cmajo.20190229.
  • Bergen-Cico D, Cico RD. Age as a predictor of cannabis use. In: Preedy VR editor. The handbook of cannabis and related pathologies: biology, pharmacology, diagnosis, and treatment. San Diego, CA: Elsevier Academic Press; 2017. p. 33–43. https://doi.org/10.1016/B978-0-12-800756-3.00005-3.
  • McKiernan A, Flemin K Canadian Youth Perceptions on Cannabis. Ottawa, ON; 2017.
  • Fataar F, Hammond D. The prevalence of vaping and smoking as modes of delivery for nicotine and cannabis among youth in canada, england and the united states. Int J Environ Res Public Health. 2019;16(21):4111. doi:10.3390/ijerph16214111.
  • Fischer B, Russell C, Sabioni P, van den Brink W, Le Foll B, Hall W, Rehm J, Room R. Lower-Risk cannabis use guidelines: a comprehensive update of evidence and recommendations. Am J Public Health. 2017;107(8):e1–e12. doi:10.2105/AJPH.2017.303818.
  • Boehnke KF, Scott JR, Litinas E, Sisley S, Williams DA, Clauw DJ. Pills to Pot: Observational analyses of cannabis substitution among medical cannabis users with chronic pain. J Pain. 2019;20(7):830–41. doi:10.1016/j.jpain.2019.01.010.
  • Statistics Canada. Canadian Tobacco, Alcohol and Drug Survey (CTADS): 2013 summary; 2013. [accessed 2022 Apr 22]. https://www.canada.ca/en/health-canada/services/canadian-alcohol-drugs-survey/2013-summary.html.
  • Heidari S, Babor TF, De Castro P, Tort S, Curno M. Sex and gender equity in research: rationale for the SAGER guidelines and recommended use. Res Integr Peer Rev. 2016;1:2.
  • Canadian Institutes of Health Research. Online training modules: integrating sex & gender in health research - sex and gender in the analysis of data from human participants; 2017. [accessed 2018 Jul 2]. http://www.cihr-irsc.gc.ca/e/49347.html.
  • Mena E, Bolte G, Bolte G, Mena E, Rommel A, Saß A-C, Pöge K, Strasser S, Holmberg C, Merz S, et al. Intersectionality-based quantitative health research and sex/gender sensitivity: a scoping review. Int J Equity Health. 2019;18(1):199. doi:10.1186/s12939-019-1098-8.