Chapter 3: Diagnosis of tuberculosis disease and drug-resistant tuberculosis

References

• LaFreniere M, Hussain H, He N, McGuire M. Tuberculosis in Canada: 2017. Can Commun Dis Rep. 2019;45(2-3):67–74. doi:10.14745/ccdr.v45i23a04.
   PubMedGoogle Scholar
• Daley CL, Gotway MB, Jasmer RM. Radiographic Manifestations of Tuberculosis: A Primer for Clinicians. Francis J. Curry National Tuberculosis Center San Francisco; 2003.
   Google Scholar
• Benito N, Garcia-Vazquez E, Horcajada JP, et al. Clinical features and outcomes of tuberculosis in transplant recipients as compared with the general population: a retrospective matched cohort study. Clin Microbiol Infect. 2015;21(7):651–658. doi:10.1016/j.cmi.2015.03.010.
   PubMed Web of Science ®Google Scholar
• Heffernan C, Barrie J, Doroshenko A, et al. Prompt recognition of infectious pulmonary tuberculosis is critical to achieving elimination goals: a retrospective cohort study. BMJ Open Resp Res. 2020;7(1):e000521. doi:10.1136/bmjresp-2019-000521.
   PubMed Web of Science ®Google Scholar
• Bailey WC, Gerald LB, Kimerling ME, et al. Predictive model to identify positive tuberculosis skin test results during contact investigations. JAMA. 2002;287(8):996–1002. doi:10.1001/jama.287.8.996.
   Web of Science ®Google Scholar
• Catanzaro A. Nosocomial tuberculosis. Am Rev Respir Dis. 1982;125(5):559–562. doi:10.1164/arrd.1982.125.5.559.
   PubMed Web of Science ®Google Scholar
• Golub JE, Bur S, Cronin WA, et al. Delayed tuberculosis diagnosis and tuberculosis transmission. Int J Tuberc Lung Dis. 2006;10(1):24–30.
   PubMed Web of Science ®Google Scholar
• Bumbacea D, Arend SM, Eyuboglu F, et al. The risk of tuberculosis in transplant candidates and recipients: a TBNET consensus statement. Eur Respir J. 2012;40(4):990–1013. doi:10.1183/09031936.00000712.
   PubMed Web of Science ®Google Scholar
• Fang HC, Lee PT, Chen CL, Wu MJ, Chou KJ, Chung HM. Tuberculosis in patients with end-stage renal disease. Int J Tuberc Lung Dis. 2004;8(1):92–97.
   PubMed Web of Science ®Google Scholar
• Andrew OT, Schoenfeld PY, Hopewell PC, Humphreys MH. Tuberculosis in patients with end-stage renal disease. Am J Med. 1980;68(1):59–65. doi:10.1016/0002-9343(80)90166-7.
   PubMed Web of Science ®Google Scholar
• Iclal I, Bilge BF, Fusun K, Galip G. Pleuropulmonary tuberculosis in patients with end-stage renal disease: findings on chest radiographs. Transplant Proc. 1999;31(3):1719–1720. doi:10.1016/S0041-1345(99)00076-7.
   PubMed Web of Science ®Google Scholar
• Toman K. Tuberculosis Case-Finding and Chemotherapy. Geneva, Switzerland: World Health Organization; 1979.
   Google Scholar
• Yeh JJ, Yu JK, Teng WB, et al. High-resolution CT for identify patients with smear-positive, active pulmonary tuberculosis. Eur J Radiol. 2012;81(1):195–201. doi:10.1016/j.ejrad.2010.09.040.
   PubMed Web of Science ®Google Scholar
• Im JG, Itoh H, Shim YS, et al. Pulmonary tuberculosis: CT findings–early active disease and sequential change with antituberculous therapy. Radiology. 1993;186(3):653–660. doi:10.1148/radiology.186.3.8430169.
   PubMed Web of Science ®Google Scholar
• Matsuoka S, Uchiyama K, Shima H, et al. Relationship between CT findings of pulmonary tuberculosis and the number of acid-fast bacilli on sputum smears. Clin Imaging. 2004;28(2):119–123. doi:10.1016/S0899-7071(03)00148-7.
   PubMed Web of Science ®Google Scholar
• Ors F, Deniz O, Bozlar U, et al. High-resolution CT findings in patients with pulmonary tuberculosis: correlation with the degree of smear positivity. J Thorac Imaging. 2007;22(2):154–159. doi:10.1097/01.rti.0000213590.29472.ce.
   PubMed Web of Science ®Google Scholar
• Yeh JJ, Neoh CA, Chen CR, Chou CY, Wu MT. A high resolution computer tomography scoring system to predict culture-positive pulmonary tuberculosis in the emergency department. PLoS One. 2014;9(4):e93847. doi:10.1371/journal.pone.0093847.
   PubMed Web of Science ®Google Scholar
• Nakanishi M, Demura Y, Ameshima S, et al. Utility of high-resolution computed tomography for predicting risk of sputum smear-negative pulmonary tuberculosis. Eur J Radiol. 2010;73(3):545–550. doi:10.1016/j.ejrad.2008.12.009.
   PubMed Web of Science ®Google Scholar
• Rizzi EB, Schinina V, Cristofaro M, et al. Detection of Pulmonary tuberculosis: comparing MR imaging with HRCT. BMC Infect Dis. 2011;11:243. doi:10.1186/1471-2334-11-243.
   PubMed Web of Science ®Google Scholar
• Yu WY, Lu PX, Assadi M, et al. Updates on (18)F-FDG-PET/CT as a clinical tool for tuberculosis evaluation and therapeutic monitoring. Quant Imaging Med Surg. 2019;9(6):1132–1146. doi:10.21037/qims.2019.05.24.
   PubMed Web of Science ®Google Scholar
• Geadas C, Acuna-Villaorduna C, Mercier G, et al. FDG-PET/CT activity leads to the diagnosis of unsuspected TB: a retrospective study. BMC Res Notes. 2018;11(1):464. doi:10.1186/s13104-018-3564-6.
   PubMedGoogle Scholar
• Murphy K, Habib SS, Zaidi SMA, et al. Computer aided detection of tuberculosis on chest radiographs: An evaluation of the CAD4TB v6 system. Sci Rep. 2020;10(1):5492. doi:10.1038/s41598-020-62148-y.
   PubMed Web of Science ®Google Scholar
• World Health Organization. Rapid Communication on Systematic Screening for Tuberculosis. Geneva. 2020. Licence: CC BY-NC-SA 3.0 IGO. Web site: https://www.who.int/publications/i/item/rapid-communication-on-the-systematic-screening-for-tuberculosis. Accessed February 26, 2022.
   Google Scholar
• Khan FA, Majidulla A, Tavaziva G, et al. Chest x-ray analysis with deep learning-based software as a triage test for pulmonary tuberculosis: a prospective study of diagnostic accuracy for culture-confirmed disease. Lancet Digit Health. 2020;2(11):e573–e581. doi:10.1016/S2589-7500(20)30221-1.
   PubMedGoogle Scholar
• Heffernan C, Rowe BH, Long R. Engaging frontline providers: an important key to eliminating tuberculosis in Canada, and other high-income countries. Can J Public Health. 2021;112(5):872–876. doi:10.17269/s41997-021-00556-x.
   PubMed Web of Science ®Google Scholar
• Lewinsohn DM, Leonard MK, LoBue PA, et al. Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children. Clin Infect Dis. 2017;64(2):111–115. doi:10.1093/cid/ciw778.
   PubMedGoogle Scholar
• Woods GL, Brown-Elliott BA, Conville PS, et al. Susceptibility Testing of Mycobacteria, Nocardiae, and Other Aerobic Actinomycetes. 2nd ed. https://clsi.org/media/1463/m24a2_sample.pdf. Wayne (PA); 2011. Clinical and Laboratory Standards Institute. Accessed February 26, 2022.
   Google Scholar
• Association of Public Health Labratories. Mycobacterium tuberculosis:Assessing Your Laboratory. 2019.
   Google Scholar
• Menzies D, Gonzalo G, Khan K, Public Health Agency of Canada. In: ed. Canadian Tuberculosis Standard, chap 6: Treatment of Latent Tuberculosis Infection, 7th ed. Can Respir J. 2013;20(Suppl A).
   Google Scholar
• Mase SR, Ramsay A, Ng V, et al. Yield of serial sputum specimen examinations in the diagnosis of pulmonary tuberculosis: a systematic review. Int J Tuberc Lung Dis. 2007;11(5):485–495.
   PubMed Web of Science ®Google Scholar
• Monkongdee P, McCarthy KD, Cain KP, et al. Yield of acid-fast smear and mycobacterial culture for tuberculosis diagnosis in people with human immunodeficiency virus. Am J Respir Crit Care Med. 2009;180(9):903–908. doi:10.1164/rccm.200905-0692OC.
   PubMed Web of Science ®Google Scholar
• Harvell JD, Hadley WK, Ng VL. Increased sensitivity of the BACTEC 460 mycobacterial radiometric broth culture system does not decrease the number of respiratory specimens required for a definitive diagnosis of pulmonary tuberculosis. J Clin Microbiol. 2000;38(10):3608–3611. doi:10.1128/JCM.38.10.3608-3611.2000.
   PubMed Web of Science ®Google Scholar
• Davis JL, Cattamanchi A, Cuevas LE, Hopewell PC, Steingart KR. Diagnostic accuracy of same-day microscopy versus standard microscopy for pulmonary tuberculosis: a systematic review and meta-analysis. Lancet Infect Dis. 2013;13(2):147–154. doi:10.1016/S1473-3099(12)70232-3.
   PubMed Web of Science ®Google Scholar
• Hepple P, Ford N, McNerney R. Microscopy compared to culture for the diagnosis of tuberculosis in induced sputum samples: a systematic review. Int j Tuberc Lung Dis. 2012;16(5):579–588. doi:10.5588/ijtld.11.0617.
   PubMed Web of Science ®Google Scholar
• Menzies D, Khan K. Canadian Tuberculosis Standards, 6th ed. Ottawa: Canadian Lung Association, Public Health Agency of Canada, Tuberculosis Prevention and Control; 2007.
   Google Scholar
• Anderson C, Inhaber N, Menzies D. Comparison of sputum induction with fiber-optic bronchoscopy in the diagnosis of tuberculosis. Am J Respir Crit Care Med. 1995;152(5):1570–1574. doi:10.1164/ajrccm.152.5.7582296.
   PubMed Web of Science ®Google Scholar
• Zar HJ, Tannenbaum E, Apolles P, Roux P, Hanslo D, Hussey G. Sputum induction for the diagnosis of pulmonary tuberculosis in infants and young children in an urban setting in South Africa. Arch Dis Child. 2000;82(4):305–308. doi:10.1136/adc.82.4.305.
   PubMed Web of Science ®Google Scholar
• American Thoracic Society. Diagnostic standards and classification of tuberculosis. Am Rev Respir Dis. 1990;142(3):725–735.
   PubMed Web of Science ®Google Scholar
• Chawla R, Pant K, Jaggi OP, Chandrashekhar S, Thukral SS. Fibreoptic bronchoscopy in smear-negative pulmonary tuberculosis. Eur Respir J. 1988;1(9):804–806.
   Web of Science ®Google Scholar
• So SY, Lam WK, Yu DY. Rapid diagnosis of suspected pulmonary tuberculosis by fiberoptic bronchoscopy. Tubercle. 1982;63(3):195–200. doi:10.1016/S0041-3879(82)80030-5.
   PubMedGoogle Scholar
• Wallace JM, Deutsch AL, Harrell JH, Moser KM. Bronchoscopy and transbronchial biopsy in evaluation of patients with suspected active tuberculosis. Am J Med. 1981;70(6):1189–1194. doi:10.1016/0002-9343(81)90826-3.
   PubMed Web of Science ®Google Scholar
• Chan HS, Sun AJ, Hoheisel GB. Bronchoscopic aspiration and bronchoalveolar lavage in the diagnosis of sputum smear-negative pulmonary tuberculosis. Lung. 1990;168(1):215–220. doi:10.1007/BF02719695.
   PubMedGoogle Scholar
• Bahammam A, Choudhri S, Long R. Utility of gastric aspirates in screening for pulmonary tuberculosis in high risk subjects:The Manitoba experience. Can J Infect Dis. 1999;10(1):69–73.
   Google Scholar
• Walters E, Demers AM, van der Zalm MM, et al. Stool Culture for Diagnosis of Pulmonary Tuberculosis in Children. J Clin Microbiol. 2017;55(12):3355–3365. doi:10.1128/JCM.00801-17.
   PubMed Web of Science ®Google Scholar
• Yeager H, Lacy J, Smith LR, LeMaistre CA. Quantitative studies of mycobacterial populations in sputum and saliva. Am Rev Respir Dis. 1967;95(6):998–1004. doi:10.1164/arrd.1967.95.6.998.
   PubMedGoogle Scholar
• Hobby GL, Holman AP, Iseman MD, Jones JM. Enumeration of tubercle bacilli in sputum of patients with pulmonary tuberculosis. Antimicrob Agents Chemother. 1973;4(2):94–104. doi:10.1128/AAC.4.2.94.
   PubMed Web of Science ®Google Scholar
• Behr MA, Warren SA, Salamon H, et al. Transmission of Mycobacterium tuberculosis from patients smear-negative for acid-fast bacilli. Lancet (London, England). 1999;353(9151):444–449. doi:10.1016/S0140-6736(98)03406-0.
   PubMed Web of Science ®Google Scholar
• Global Laboratory Initiative WHO Stop TB Partnership. Mycobacteriology laboratory manual. 2014.
   Google Scholar
• Ling DI, Flores LL, Riley LW, Pai M. Commercial nucleic-acid amplification tests for diagnosis of pulmonary tuberculosis in respiratory specimens: meta-analysis and meta-regression. PLoS One. 2008;3(2):e1536. doi:10.1371/journal.pone.0001536.
   PubMed Web of Science ®Google Scholar
• Flores LL, Pai M, Colford JM, Jr., Riley LW. In-house nucleic acid amplification tests for the detection of Mycobacterium tuberculosis in sputum specimens: meta-analysis and meta-regression. BMC Microbiol. 2005;5:55. doi:10.1186/1471-2180-5-55.
   PubMed Web of Science ®Google Scholar
• Sarmiento OL, Weigle KA, Alexander J, Weber DJ, Miller WC. Assessment by meta-analysis of PCR for diagnosis of smear-negative pulmonary tuberculosis. J Clin Microbiol. 2003;41(7):3233–3240. doi:10.1128/JCM.41.7.3233-3240.2003.
   PubMed Web of Science ®Google Scholar
• Zifodya JS, Kreniske JS, Schiller I, et al. Xpert Ultra versus Xpert MTB/RIF for pulmonary tuberculosis and rifampicin resistance in adults with presumptive pulmonary tuberculosis. Cochrane Database Syst Rev. 2021;2:CD009593. doi:10.1002/14651858.CD009593.pub5.
   PubMedGoogle Scholar
• World Health Organization. WHO meeting report of a technical expert consultation: non-inferiority analysis of Xpert MTB/RIF Ultra compared to Xpert MTB/RIF. 2017.
   Google Scholar
• Nathavitharana RR, Cudahy PG, Schumacher SG, Steingart KR, Pai M, Denkinger CM. Accuracy of line probe assays for the diagnosis of pulmonary and multidrug-resistant tuberculosis: a systematic review and meta-analysis. Eur Respir J. 2017;49(1):1601075. doi:10.1183/13993003.01075-2016.
   PubMed Web of Science ®Google Scholar
• Steingart KR, Flores LL, Dendukuri N, et al. Commercial serological tests for the diagnosis of active pulmonary and extrapulmonary tuberculosis: an updated systematic review and meta-analysis. PLoS Med. 2011;8(8):e1001062. doi:10.1371/journal.pmed.1001062.
   PubMed Web of Science ®Google Scholar
• Dowdy DW, Steingart KR, Pai M. Serological testing versus other strategies for diagnosis of active tuberculosis in India: a cost-effectiveness analysis. PLoS Med. 2011;8(8):e1001074. doi:10.1371/journal.pmed.1001074.
   PubMed Web of Science ®Google Scholar
• Morris K. WHO recommends against inaccurate tuberculosis tests. Lancet. 2011;377(9760):113–114. doi:10.1016/S0140-6736(11)60005-6.
   PubMed Web of Science ®Google Scholar
• World Health Organization. WHO Operational Handbook on Tuberculosis. Module 3: diagnosis—Rapid Diagnostics for Tuberculosis Detection 2021 Update. https://www.who.int/publications/i/item/9789240030589. 2021. Licence: CC BY-NC-SA 3.0 IGO. Accessed February 26, 2022.
   Google Scholar
• Aggarwal AN, Agarwal R, Sehgal IS, Dhooria S. Adenosine deaminase for diagnosis of tuberculous pleural effusion: A systematic review and meta-analysis. PLoS One. 2019;14(3):e0213728. doi:10.1371/journal.pone.0213728.
   PubMed Web of Science ®Google Scholar
• Bulterys MA, Wagner B, Redard-Jacot M, et al. Point-Of-Care Urine LAM Tests for Tuberculosis Diagnosis: A Status Update. J Clin Med. 2019;9(1):111.
   Web of Science ®Google Scholar
• Forbes BA, Hall GS, Miller MB, et al. Practical Guidance for Clinical Microbiology Laboratories: Mycobacteria. Clin Microbiol Rev. 2018;31(2):e00038-17. doi:10.1128/CMR.00038-17.
   Web of Science ®Google Scholar
• Government of Canada. Human Pathogens and Toxins Regulations. 2015.
   Google Scholar
• Government of Canada. Canadian Biosafety Standard (CBS), 2nd ed. 2015. https://www.canada.ca/en/public-health/services/canadian-biosafety-standards-guidelines/second-edition.html. Accessed on February 26, 2022.
   Google Scholar
• Public Health Agency of Canada. Biosafety Directive for Mycobacterium tuberculosis Complex (MTBC). 2017.
   Google Scholar
• Transport Canada. Transportation of dangerous goods in Canada. AEAD 17002250 Web site. https://tc.canada.ca/en/dangerous-goods/transportation-dangerous-goods-canada. Published 2021. Accessed February 26, 2022.
   Google Scholar
• Steingart KR, Henry M, Ng V, et al. Fluorescence versus conventional sputum smear microscopy for tuberculosis: a systematic review. Lancet Infect Dis. 2006;6(9):570–581. doi:10.1016/S1473-3099(06)70578-3.
   PubMed Web of Science ®Google Scholar
• Steingart KR, Ramsay A, Pai M. Optimizing sputum smear microscopy for the diagnosis of pulmonary tuberculosis. Expert Rev anti Infect Ther. 2007;5(3):327–331. doi:10.1586/14787210.5.3.327.
   PubMed Web of Science ®Google Scholar
• Steingart KR, Ng V, Henry M, et al. Sputum processing methods to improve the sensitivity of smear microscopy for tuberculosis: a systematic review. Lancet Infect Dis. 2006;6(10):664–674. doi:10.1016/S1473-3099(06)70602-8.
   PubMed Web of Science ®Google Scholar
• Salfinger M, Pfyffer GE. The new diagnostic mycobacteriology laboratory. Eur J Clin Microbiol Infect Dis. 1994;13(11):961–979. doi:10.1007/BF02111498.
   PubMed Web of Science ®Google Scholar
• Clinical and Laboratory Standards Institute. Laboratory Detection and Identification of Mycobacteria. Clsi Guideline M48 2018. M48.
   Google Scholar
• Association of Public Health Laboratories. AFB Smear Microscopy. https://www.aphl.org/programs/infectious_disease/tuberculosis/TBCore/TB_AFB_Smear_Microscopy_TrainerNotes.pdf. Accessed February 26, 2022.
   Google Scholar
• Health Canada. Medical Devices Active Licence Listing. https://health-products.canada.ca/mdall-limh/prepareSearch-preparerRecherche.do?type=archived_archive. Published 2012. Updated 2021. Accessed.
   Google Scholar
• Steingart KR, Sohn H, Schiller I, et al. Xpert(R) MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults. Cochrane Database Syst Rev. 2014;2014(1):CD009593.
   PubMed Web of Science ®Google Scholar
• Boehme CC, Nicol MP, Nabeta P, et al. Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicentre implementation study. Lancet. 2011;377(9776):1495–1505. doi:10.1016/S0140-6736(11)60438-8.
   PubMed Web of Science ®Google Scholar
• Tortoli E, Cichero P, Piersimoni C, Simonetti MT, Gesu G, Nista D. Use of BACTEC MGIT 960 for recovery of mycobacteria from clinical specimens: multicenter study. J Clin Microbiol. 1999;37(11):3578–3582. doi:10.1128/JCM.37.11.3578-3582.1999.
   PubMed Web of Science ®Google Scholar
• Clinical and Laboratory Standards Institute. Molecular Diagnostic Methods for Infectious Diseases. 3rd Edition. 2015. https://clsi.org/standards/products/molecular-diagnostics/documents/mm03/. Accessed August 8, 2021.
   Google Scholar
• Clinical and Laboratory Standards Institute. MM09-A2: Nucleic Acid Sequencing Methods in Diagnostic Labratory Medicine; Approved Guideline, 2nd ed.; 2004. https://clsi.org/standards/products/molecular-diagnostics/documents/mm09/. Accessed August 8, 2021.
   Google Scholar
• Al Zahrani K, Al Jahdali H, Poirier L, Rene P, Menzies D. Yield of smear, culture and amplification tests from repeated sputum induction for the diagnosis of pulmonary tuberculosis. Int J Tuberc Lung Dis. 2001;5(9):855–860.
   PubMed Web of Science ®Google Scholar
• Heifets LB, Desmond EP. Clinical Mycobacteriology (Tuberculosis) Laboratory: Services and Methods. In: Cole S, Eisenach K, McMurray D, Jacobs W, eds. Tuberculosis and the Tubercle Bacillus. Washington DC: ASM press; 2005. 49–69.
   Google Scholar
• Burman WJ, Stone BL, Reves RR, et al. The incidence of false-positive cultures for Mycobacterium tuberculosis. Am J Respir Crit Care Med. 1997;155(1):321–326. doi:10.1164/ajrccm.155.1.9001331.
   PubMed Web of Science ®Google Scholar
• Ruddy M, McHugh TD, Dale JW, et al. Estimation of the rate of unrecognized cross-contamination with mycobacterium tuberculosis in London microbiology laboratories. J Clin Microbiol. 2002;40(11):4100–4104. doi:10.1128/JCM.40.11.4100-4104.2002.
   PubMed Web of Science ®Google Scholar
• Small PM, McClenny NB, Singh SP, Schoolnik GK, Tompkins LS, Mickelsen PA. Molecular strain typing of Mycobacterium tuberculosis to confirm cross-contamination in the mycobacteriology laboratory and modification of procedures to minimize occurrence of false-positive cultures. J Clin Microbiol. 1993;31(7):1677–1682. doi:10.1128/jcm.31.7.1677-1682.1993.
   PubMed Web of Science ®Google Scholar
• Diagnostic Standards and Classification of Tuberculosis in Adults and Children. This official statement of the American Thoracic Society and the Centers for Disease Control and Prevention was adopted by the ATS Board of Directors, July 1999. This statement was endorsed by the Council of the Infectious Disease Society of America, September 1999. Am J Respir Crit Care Med. 2000;161(4 Pt 1):1376–1395.
   PubMed Web of Science ®Google Scholar
• Clinical and Laboratory Standards Institute. Susceptibility Testing of Mycobacteria, Nocardia Spp., and Other Aerobic Actinomycetes. 3rd ed.; 2018. https://clsi.org/media/2620/m24ed3_sample.pdf. Accessed February 26, 2022.
   Google Scholar
• Danchuk SN, McIntosh F, Jamieson FB, May K, Behr MA. Bacillus Calmette-Guerin strains with defined resistance mutations: a new tool for tuberculosis laboratory quality control. Clin Microbiol Infect. 2020;26(3):384 e385–384 e388.
   Web of Science ®Google Scholar
• Penn-Nicholson A, Georghiou SB, Ciobanu N, et al. Detection of isoniazid, fluoroquinolone, ethionamide, amikacin, kanamycin, and capreomycin resistance by the Xpert MTB/XDR assay: a cross-sectional multicentre diagnostic accuracy study. Lancet Infect Dis. 2021; 22(2):242–249.
   Web of Science ®Google Scholar
• Ling DI, Zwerling AA, Pai M. GenoType MTBDR assays for the diagnosis of multidrug-resistant tuberculosis: a meta-analysis. Eur Respir J. 2008;32(5):1165–1174. doi:10.1183/09031936.00061808.
   PubMed Web of Science ®Google Scholar
• Meehan CJ, Goig GA, Kohl TA, et al. Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues. Nat Rev Microbiol. 2019;17(9):533–545. doi:10.1038/s41579-019-0214-5.
   PubMed Web of Science ®Google Scholar
• CRyPTIC Consortium and the 100 GP. Prediction of susceptibility to first-line tuberculosis drugs by DNA sequencing. New Eng J Med. 2018;379(15):1403–1415.
   Web of Science ®Google Scholar
• Jajou R, van der Laan T, de Zwaan R, et al. WGS more accurately predicts susceptibility of Mycobacterium tuberculosis to first-line drugs than phenotypic testing. J Antimicrob Chemother. 2019;74(9):2605–2616. doi:10.1093/jac/dkz215.
   PubMed Web of Science ®Google Scholar
• Shea J, Halse TA, Lapierre P, et al. Comprehensive Whole-Genome Sequencing and Reporting of Drug Resistance Profiles on Clinical Cases of Mycobacterium tuberculosis in New York State. J Clin Microbiol. 2017;55(6):1871–1882. doi:10.1128/JCM.00298-17.
   PubMed Web of Science ®Google Scholar
• Brown AC, Bryant JM, Einer-Jensen K, et al. Rapid Whole-Genome Sequencing of Mycobacterium tuberculosis Isolates Directly from Clinical Samples. J Clin Microbiol. 2015;53(7):2230–2237. doi:10.1128/JCM.00486-15.
   PubMed Web of Science ®Google Scholar
• Votintseva AA, Bradley P, Pankhurst L, et al. Same-Day Diagnostic and Surveillance Data for Tuberculosis via Whole-Genome Sequencing of Direct Respiratory Samples. J Clin Microbiol. 2017;55(5):1285–1298. doi:10.1128/JCM.02483-16.
   PubMed Web of Science ®Google Scholar
• Doberne D, Gaur RL, Banaei N. Preanalytical delay reduces sensitivity of QuantiFERON-TB gold in-tube assay for detection of latent tuberculosis infection. J Clin Microbiol. 2011;49(8):3061–3064. doi:10.1128/JCM.01136-11.
   PubMed Web of Science ®Google Scholar
• Herrera V, Yeh E, Murphy K, Parsonnet J, Banaei N. Immediate incubation reduces indeterminate results for QuantiFERON-TB Gold in-tube assay. J Clin Microbiol. 2010;48(8):2672–2676. doi:10.1128/JCM.00482-10.
   PubMed Web of Science ®Google Scholar
• Oxford Immunotec. T-SPOT. TB package insert PI- TB8-IVD- UK-V4. 2012.
   Google Scholar
• Oxford Immunotec. T-SPOT. TB training guide, TH- TB- UK-V3 300407. http://www.oxfordimmunotec.com/north-america/wp-content/uploads/sites/2/TG-TB-US-V5.pdf. Published 2012. Accessed February 26, 2022.
   Google Scholar
• Oxford Immunotec. TB T-Cell Xtend package insert, PI-TT.610- US-V4 https://www.tspot.com/resources/resource/t-cell-xtend-package-insert/. Published 2012. Accessed February 26, 2021.
   Google Scholar