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Structural Heart
The Journal of the Heart Team
Volume 4, 2020 - Issue 6
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Review Article

Peri-Device Leaks after Percutaneous Left Atrial Appendage Closure: Clinical Significance and Unmet Diagnostic Needs

, MD, MSc, , MD, PhD, , PhD, , MD, FHRS, , MD, PhD, FEHRA, FHRS, FESC, , MD, , MD, , MD & , MD show all
Pages 475-481 | Received 20 May 2020, Accepted 24 Aug 2020, Published online: 23 Nov 2020

References

  • Stroke Risk in Atrial Fibrillation Working Group. Independent predictors of stroke in patients with atrial fibrillation: a systematic review. Neurology. 2007;69(6):546–554. doi:10.1212/01.wnl.0000267275.68538.8d.
  • Hart RG, Pearce LA, Aguilar MI. Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med. 2007;146(12):857–867. doi:10.7326/0003-4819-146-12-200706190-00007.
  • Granger CB, Alexander JH, McMurray JJ, et al. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med. 2011;365:981–992. doi:10.1056/NEJMoa1107039.
  • Connolly SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med. 2009;361:1139–1151. doi:10.1056/NEJMoa0905561.
  • Patel MR, Mahaffey KW, Garg J, et al. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med. 2011;365(10):883–891. doi:10.1056/NEJMoa1009638.
  • Giugliano RP, Ruff CT, Braunwald E, et al. Edoxaban versus warfarin in patients with atrial fibrillation. N Engl J Med. 2013;369(22):2093–2104. doi:10.1056/NEJMoa1310907.
  • Camm AJ, Accetta G, Ambrosio G, et al. Evolving antithrombotic treatment patterns for patients with newly diagnosed atrial fibrillation. Heart. 2017;103(4):307–314. doi:10.1136/heartjnl-2016-309832.
  • O’Brien EC, Holmes DN, Ansell JE, et al. Physician practices regarding contraindications to oral anticoagulation in atrial fibrillation: findings from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry. Am Heart J. 2014;167(4):601–609 e1. doi:10.1016/j.ahj.2013.12.014.
  • Cresti A, Garcia-Fernandez MA, Sievert H, et al. Prevalence of extra-appendage thrombosis in non-valvular atrial fibrillation and atrial flutter in patients undergoing cardioversion: a large transoesophageal echo study. EuroIntervention. 2019;15(3):e225–e230. doi:10.4244/EIJ-D-19-00128.
  • January CT, Wann LS, Calkins H, et al. AHA/ACC/HRS focused update of the 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association task force on clinical practice guidelines and the heart rhythm society. J Am Coll Cardiol. 2019;74(1):104–132. doi:10.1016/j.jacc.2019.01.011.
  • Reddy VY, Sievert H, Halperin J, et al. Percutaneous left atrial appendage closure vs warfarin for atrial fibrillation: a randomized clinical trial. JAMA. 2014;312:1988–1998. doi:10.1001/jama.2014.15192.
  • Holmes DR Jr., Kar S, Price MJ, et al. Prospective randomized evaluation of the Watchman Left Atrial Appendage Closure device in patients with atrial fibrillation versus long-term warfarin therapy: the PREVAIL trial. J Am Coll Cardiol. 2014;64(1):1–12. doi:10.1016/j.jacc.2014.04.029.
  • Holmes DR Jr., Reddy VY, Gordon NT, et al. Long-term safety and efficacy in continued access left atrial appendage closure registries. J Am Coll Cardiol. 2019;74(23):2878–2889. doi:10.1016/j.jacc.2019.09.064.
  • Reddy VY, Doshi SK, Kar S, et al. 5-year outcomes after left atrial appendage closure: from the PREVAIL and PROTECT AF trials. J Am Coll Cardiol. 2017;70:2964–2975. doi:10.1016/j.jacc.2017.10.021.
  • Raphael CE, Friedman PA, Saw J, Pislaru SV, Munger TM, Holmes DR Jr. Residual leaks following percutaneous left atrial appendage occlusion: assessment and management implications. EuroIntervention. 2017;13(10):1218–1225. doi:10.4244/EIJ-D-17-00469.
  • Gianni C, Di Biase L, Trivedi C, et al. Clinical implications of leaks following left Atrial appendage ligation with the LARIAT device. JACC: Cardiovascular Interventions. 2016;9(10):1051–1057. doi:10.1016/j.jcin.2016.01.038.
  • Asmarats L, Rodes-Cabau J. Percutaneous left atrial appendage closure: current devices and clinical outcomes. Circulation: Cardiovascular Interventions. 2017;10(11). doi:10.1161/CIRCINTERVENTIONS.117.005359.
  • Moussa Pacha H, Al-Khadra Y, Soud M, Darmoch F, Moussa Pacha A, Alraies MC. Percutaneous devices for left atrial appendage occlusion: A contemporary review. World J Cardiol. 2019;11(2):57–70. doi:10.4330/wjc.v11.i2.57.
  • Berti S, Santoro G, Brscic E, et al. Left atrial appendage closure using AMPLATZER devices: A large, multicenter, Italian registry. Int J Cardiol. 2017;248:103–107. doi:10.1016/j.ijcard.2017.07.052.
  • Saw J, Fahmy P, DeJong P, et al. Cardiac CT angiography for device surveillance after endovascular left atrial appendage closure. European Heart Journal – Cardiovascular Imaging. 2015;16(11):1198–1206. doi:10.1093/ehjci/jev067.
  • Granier M, Laugaudin G, Massin F, et al. Occurrence of incomplete endothelialization causing residual permeability after left atrial appendage closure. J Invasive Cardiol. 2018;30:245–250.
  • Jaguszewski M, Manes C, Puippe G, et al. Cardiac CT and echocardiographic evaluation of peri-device flow after percutaneous left atrial appendage closure using the AMPLATZER cardiac plug device. Catheter Cardiovasc Interv. 2015;85(2):306–312. doi:10.1002/ccd.25667.
  • Beigel R, Wunderlich NC, Ho SY, Arsanjani R, Siegel RJ. The left atrial appendage: anatomy, function, and noninvasive evaluation. JACC Cardiovasc Imaging. 2014;7(12):1251–1265. doi:10.1016/j.jcmg.2014.08.009.
  • Nguyen A, Gallet R, Riant E, et al. Peridevice leak after left atrial appendage closure: incidence, risk factors, and clinical impact. Cana J Cardiol. 2019;35(4):405–412. doi:10.1016/j.cjca.2018.12.022.
  • Prakash R, Saw J. Imaging for percutaneous left atrial appendage closure. Catheter Cardiovasc Interv. 2018;92(2):437–450. doi:10.1002/ccd.26828.
  • Aryana A, Singh SK, Singh SM, et al. Association between incomplete surgical ligation of left atrial appendage and stroke and systemic embolization. Heart Rhythm. 2015;12(7):1431–1437. doi:10.1016/j.hrthm.2015.03.028.
  • Garcia-Fernandez MA, Perez-David E, Quiles J, et al. Role of left atrial appendage obliteration in stroke reduction in patients with mitral valve prosthesis: a transesophageal echocardiographic study. J Am Coll Cardiol. 2003;42(7):1253–1258. doi:10.1016/S0735-1097(03)00954-9.
  • Tzikas A, Shakir S, Gafoor S, et al. Left atrial appendage occlusion for stroke prevention in atrial fibrillation: multicentre experience with the AMPLATZER Cardiac Plug. EuroIntervention. 2016;11(10):1170–1179. doi:10.4244/EIJY15M01_06.
  • Saw J, Tzikas A, Shakir S, et al. Incidence and clinical impact of device-associated thrombus and peri-device leak following left atrial appendage closure with the amplatzer cardiac plug. JACC Cardiovasc Interv. 2017;10(4):391–399. doi:10.1016/j.jcin.2016.11.029.
  • Viles-Gonzalez JF, Kar S, Douglas P, et al. The clinical impact of incomplete left atrial appendage closure with the Watchman Device in patients with atrial fibrillation: a PROTECT AF (percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation) substudy. J Am Coll Cardiol. 2012;59(10):923–929. doi:10.1016/j.jacc.2011.11.028.
  • Holmes DR, Reddy VY, Turi ZG, et al. Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomised non-inferiority trial. Lancet. 2009;374(9689):534–542. doi:10.1016/S0140-6736(09)61343-X.
  • Pillarisetti J, Reddy YM, Gunda S, et al. Endocardial (Watchman) vs epicardial (Lariat) left atrial appendage exclusion devices: understanding the differences in the location and type of leaks and their clinical implications. Heart Rhythm. 2015;12(7):1501–1507. doi:10.1016/j.hrthm.2015.03.020.
  • Lim YM, Kim JS, Kim TH, et al. Delayed left atrial appendage contrast filling in computed tomograms after percutaneous left atrial appendage occlusion. J Cardiol. 2017;70(6):571–577. doi:10.1016/j.jjcc.2017.04.007.
  • Sivasambu B, Arbab-Zadeh A, Hays A, Calkins H, Berger RD. Delayed endothelialization of watchman device identified with cardiac CT. J Cardiovasc Electrophysiol. 2019;30(8):1319–1324. doi:10.1111/jce.14053.
  • Freixa X, Abualsaud A, Chan J, et al. Left atrial appendage occlusion: initial experience with the Amplatzer™ Amulet™. Int J Cardiol. 2014;174(3):492–496. doi:10.1016/j.ijcard.2014.03.154.
  • Lopez Minguez JR, Asensio JM, Gragera JE, et al. Two-year clinical outcome from the Iberian registry patients after left atrial appendage closure. Heart. 2015;101(11):877–883. doi:10.1136/heartjnl-2014-306332.
  • Landmesser U, Schmidt B, Nielsen-Kudsk JE, et al. Left atrial appendage occlusion with the AMPLATZER Amulet device: periprocedural and early clinical/echocardiographic data from a global prospective observational study. EuroIntervention. 2017;13(7):867–876. doi:10.4244/EIJ-D-17-00493.
  • Bartus K, Gafoor S, Tschopp D, et al. Left atrial appendage ligation with the next generation LARIAT(+) suture delivery device: early clinical experience. Int J Cardiol. 2016;215:244–247. doi:10.1016/j.ijcard.2016.04.005.
  • Lakkireddy D, Afzal MR, Lee RJ, et al. Short and long-term outcomes of percutaneous left atrial appendage suture ligation: results from a US multicenter evaluation. Heart Rhythm. 2016;13(5):1030–1036. doi:10.1016/j.hrthm.2016.01.022.
  • Huang H, Liu Y, Xu Y, et al. Percutaneous left atrial appendage closure with the lambre device for stroke prevention in atrial fibrillation: a prospective, multicenter clinical study. JACC: Cardiovascular Interventions. 2017;10(21):2188–2194. doi:10.1016/j.jcin.2017.06.072.
  • Park JW, Sievert H, Kleinecke C, et al. Left atrial appendage occlusion with lambre in atrial fibrillation: initial European experience. Int J Cardiol. 2018;265:97–102. doi:10.1016/j.ijcard.2018.02.120.
  • Bellmann B, Schnupp S, Kühnlein P, et al. Left atrial appendage closure with the new Occlutech® device: first in man experience and neurological outcome. J Cardiovasc Electrophysiol. 2017;28(3):315–320. doi:10.1111/jce.13141.
  • Regueiro A, Bernier M, O’Hara G, et al. Left atrial appendage closure: initial experience with the ultraseal device. Catheter Cardiovasc Interv. 2017;90(5):817–823. doi:10.1002/ccd.260870.
  • Asmarats L, Masson JB, Pagnotta PA, et al. Percutaneous left atrial appendage closure with the ultraseal device: insights from the initial multicenter experience. JACC Cardiovasc Interv. 2018;11(19):1932–1941. doi:10.1016/j.jcin.2018.05.023.
  • Suradi HS, Hijazi ZM. Left atrial appendage closure: outcomes and challenges. Neth Heart J. 2017;25(2):143–151. doi:10.1007/s12471-016-0929-0.
  • Saw J, Nielsen-Kudsk JE, Bergmann M, et al. Antithrombotic therapy and device-related thrombosis following endovascular left atrial appendage closure. JACC: Cardiovascular Interventions. 2019;12(11):1067–1076. doi:10.1016/j.jcin.2018.11.001.
  • Delgado V, Bax JJ. Atrial functional mitral regurgitation: from mitral annulus dilatation to insufficient leaflet remodeling. Circulation: Cardiovascular Imaging. 2017;10(3). doi:10.1161/CIRCIMAGING.117.006239.
  • Fauchier L, Cinaud A, Brigadeau F, et al. Device-related thrombosis after percutaneous left atrial appendage occlusion for atrial fibrillation. J Am Coll Cardiol. 2018;71(14):1528–1536. doi:10.1016/j.jacc.2018.01.076.
  • Korsholm K, Berti S, Iriart X, et al. Expert recommendations on cardiac computed tomography for planning transcatheter left atrial appendage occlusion. JACC: Cardiovascular Interventions. 2020;13(3):277–292. doi:10.1016/j.jcin.2019.08.054.
  • Eng MH, Wang DD, Greenbaum AB, et al. Prospective, randomized comparison of 3-dimensional computed tomography guidance versus TEE data for left atrial appendage occlusion (PRO3DLAAO). Catheter Cardiovasc Interv. 2018;92(2):401–407. doi:10.1002/ccd.27514.
  • Alkhouli M, Hijazi ZM, Holmes DR Jr., Rihal CS, Wiegers SE. Intracardiac echocardiography in structural heart disease interventions. JACC: Cardiovascular Interventions. 2018;11(21):2133–2147. doi:10.1016/j.jcin.2018.06.056.
  • Nucifora G, Faletra FF, Regoli F, et al. Evaluation of the left atrial appendage with real-time 3-dimensional transesophageal echocardiography: implications for catheter-based left atrial appendage closure. Circulation. 2011;4(5):514–523. doi:10.1161/CIRCIMAGING.111.963892.
  • Freitas-Ferraz AB, Bernier M, Vaillancourt R, et al. Safety of transesophageal echocardiography to guide structural cardiac interventions. J Am Coll Cardiol. 2020;75(25):3164–3173. doi:10.1016/j.jacc.2020.04.069.