1,706
Views
4
CrossRef citations to date
0
Altmetric
Pharmacology and Pharmaceutics

Antihyperlipidemic and hepatic antioxidant effects of Leek leaf methanol extract in high fat diet-fed rats

, ORCID Icon, , ORCID Icon & ORCID Icon
Pages 373-385 | Received 20 Feb 2020, Accepted 29 Jun 2020, Published online: 22 Jul 2020

References

  • Adluri RS, Nagarajan D, Periyaswamy V, Venugopal PM. 2008. Dose-response effect of ferulic acid against nicotine-induced tissue damage and altered lipid levels in experimental rats: a pathohistological evaluation. Fundam Clin Pharmacol. 22(5):557–567.
  • Ahotupa M. 2017. Oxidized lipoprotein lipids and atherosclerosis. Free Radic Res. 51(4):439–447.
  • American Diabetes Association. 2018. 9. Cardiovascular disease and risk management: standards of medical care in diabetes-2018. Diabetes Care. 41(Suppl 1):S86–S104.
  • Ballantyne CM, Jones PH. 2014. Overview of general approach to management of elevated low-density lipoprotein cholesterol and mixed dyslipidemia, high triglycerides, and low high-density lipoprotein cholesterol. In: Ballantyne CM, editor. Clinical Lipidology: A Companion to Braunwald's heart disease. Philadelphia: Elsevier Health Sciences; p. 199–201.
  • Belakhdar G, Benjouad A, Abdennebi EH. 2015. Determination of some bioactive chemical constituents from Thesium humile Vahl. J Mater Environ Sci. 6(10):2778–2783.
  • Bernaert N, De Paepe D, Bouten C, De Clercq H, Stewart D, Van Bockstaele E, et al. 2012. Antioxidant capacity, total phenolic and ascorb ate content as a function of the genetic diversity of leek (Allium ampeloprasum var. porrum). Food Chem. 134:669–677.
  • Bernaert N, Wouters D, De Vuyst L, De Paepe D, De Clercq H, Van Bockstaele E, et al. 2013. Antioxidant changes of leek (Allium ampeloprasum var. porrum) during spontaneous fermentation of the white shaft and green leaves. J Sci Food Agric. 93:2146–2153.
  • Chong PH, Seeger JD, Franklin C. 2001. Clinically relevant differences between the statins: implications for therapeutic selection. Am J Med. 111(5):390–400.
  • Easwaran L, Ramani A. 2014. . phytochemical examination and gc-ms studies of the medicinal plant - Naravelia zeylanica. IJRDPL. 3(5):1180–1188.
  • El-Din SH, Sabra AN, Hammam OA, Ebeid FA, El-Lakkany NM. 2014. Pharmacological and antioxidant actions of garlic and.or onion in non-alcoholic fatty liver disease (NAFLD) in rats. J Egypt Soc Parasitol. 44(2):295–308.
  • Elahi MM, Kong YX, Matata BM. 2009. Oxidative stress as a mediator of cardiovascular disease. Oxid Med Cell Longev. 2(5):259–269.
  • Farooqi IS, Leptin OS. 2009. . a pivotal regulator of human energy homeostasis. Am J Clin Nutr. 89(3):980S–984S.
  • Fatoorechi V, Rismanchi M, Nasrollahzadeh J. 2016. Effects of Persian leek (Allium ampeloprasum) on hepatic lipids and the expression of proinflammatory gene in hamsters fed a high-fat/ highcholesterol diet. Avicenna J Phytomed. 6(4):418–424.
  • Folch J, Lees M, Sloane Stanley GH. 1957. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem. 226(1):497–509.
  • Friedman JM. 2009. Obesity: Causes and control of excess body fat. Nature. 459(7245):340–342.
  • Ganesh M, Mohankumar M. 2017. Extraction and identification of bioactive components in Sida cordata (Burm.f.) using gas chromatography-mass spectrometry. J Food Sci Technol. 54(10):3082–3091.
  • Hall KD, Hammond RA, Rahmandad H. 2014. Dynamic interplay among homeostatic, hedonic, and cognitive feedback circuits regulating body weight. Am J Public Health. 104(7):1169–1175.
  • Hart DJ, Scott KJ. 1995. Development and evaluation of an HPLC method for the analysis of carotenoids in foods, and the measurement of the carotenoid content of vegetables and fruits commonly consumed in the UK. Food Chem. 54:101–111.
  • Hasan TN, Ahmed SN, Aalam SMM, Kumar C, Shafi G. 2007. Evaluation of cichorium extract for the growth supporting property in rat hepatocyte primary culture. Asian J Plant Sci. 6:431–434.
  • Jain KK. 2017. Personalized Management of cardiovascular disorders. Med Princ Pract. 26(5):399–414.
  • Jayathilake C, Rizliya V, Liyanage R. 2016. Antioxidant and free radical scavenging capacity of extensively used medicinal plants in Sri Lanka. Proced Food Science. 6:123–126.
  • Jin CJ, Engstler AJ, Ziegenhardt D, Bischoff SC, Trautwein C, Bergheim I. 2017. Loss of lipopolysaccharide-binding protein attenuates the development of diet-induced non-alcoholic fatty liver disease in mice. J Gastroenterol Hepatol. 32(3):708–715.
  • Jing L, Zhang Y, Fan S, et al. 2013. Preventive and ameliorating effects of citrus D-limonene on dyslipidemia and hyperglycemia in mice with high-fat diet-induced obesity. Eur J Pharmacol. 715(1-3):46–55.
  • Jin Son M, W Rico C, Hyun Nam S, Young Kang M. 2010. Influence of oryzanol and ferulic acid on the lipid metabolism and antioxidative status in high fat-fed mice. J Clin Biochem Nutr. 46(2):150–156.
  • Jones P, Kafonek S, Laurora I, Hunninghake D. 1998. Comparative dose efficacy study of atorvastatin versus simvastatin, pravastatin, lovastatin, and fluvastatin in patients With hypercholesterolemia (The CURVES study). Am J Cardiol. 81(5):582–587.
  • Joseph TD, Gary CY, Michael P L, Stuart TH, Thomas DN, Vicki E. 2020. Pharmacotherapy: a pathophysiologic approach. USA: McGraw-Hill Education. Eleventh edition.
  • Kakimoto PA, Kowaltowski AJ. 2016. Effects of high fat diets on rodent liver bioenergetics and oxidative imbalance. Redox Biol. 8:216–225.
  • Karimi N, Bareemizadeh F, Ghasempour H. 2013. The comparision GC and GC-MS of Allium Ampeloprasum L. Var, Atroviolaceum Regel And Allium Iranicum Wendelbo. Tehran, Iran: 2nd National Congress on Medicinal Plants.
  • Khaleel EF, Abdel-Aleem GA, Mostafa DG. 2018. Resveratrol improves high-fat diet induced fatty liver and insulin resistance by concomitantly inhibiting proteolytic cleavage of sterol regulatory element-binding proteins, free fatty acid oxidation, and intestinal triglyceride absorption. Can J Physiol Pharmacol. 96(2):145–157.
  • Kim JL, Chae IS, Kang YH, Kang JS. 2008. Effect of onion and beet on plasma and liver lipids, platelet aggregation, and erythrocyte Na efflux in simvastatin treated hypercholesterolmic rats. Nutr Res Pract. 2:211–217.
  • Kim HC, Song JM, Kim CJ, Yoon SY, Kim IR, Park BS, Shin SH. 2015. Combined effect of bisphosphonate and recombinant human bone morphogenetic protein 2 on bone healing of rat calvarial defects. Maxillofac Plast Reconstr Surg. 37:16.
  • Kumar SS, Samydurai P, Ramakrishnan R, Nagarajan N. 2014. Gas chromatography and mass spectrometry analysis of bioactive constituents of Adiantum capillus-veneris. Int J Pharm. 6(4):60–63.
  • Li C, Zhang W, Zhou F, Chen C, Zhou L, Li Y, et al. 2013. Cholesteryl ester transfer protein inhibitors in the treatment of dyslipidemia: a systematic review and meta-analysis. PLoS One. 8:e77049.
  • Licholai JA, Nguyen KP, Fobbs WC, Schuster CJ, Ali MA, Kravitz AV. 2018. Why do mice overeat high-Fat diets? How high-fat diet alters the regulation of daily caloric intake in mice. Obesity (Silver Spring). 26(6):1026–1033.
  • Liu L, Yeh YY. 2001. Water-soluble organosulfur compounds of garlic inhibit fatty acid and triglyceride syntheses in cultured rat hepatocytes. Lipids. 36:395–400.
  • Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. 1951. J Biol Chem. 193:265. (The original method).
  • Lutz TA, Woods SC. 2012. Overview of animal models of obesity. Curr Protoc Pharmacol. Chapter 5:Unit5.61.
  • McCrohon JA, Nakhla S, Jessup W, Stanley KK, Celermajer DS. 1999. Estrogen and progesterone reduce lipid accumulation in human monocyte-derived macrophages: A sex-specific effect. Circulation. 100:2319–2325.
  • Mæhre HK, Jensen IJ, Eilertsen KE. 2016. Enzymatic pre-treatment increases the protein bioaccessibility and extractability in Dulse (Palmaria palmata). Mar Drugs. 14(11):196.
  • Rehana BH, Nagarajan N. 2013. GC–MS determination of bioactive components of Wedelia chinensis (Osbeck) Merrill. J Chem Pharm. 5(4):279–285.
  • Rolo AP, Gomes AP, Palmeira CM. 2012. Regulation of mitochondrial biogenesis in metabolic syndrome. Curr Drug Targets. 12(6):872–878.
  • Shenoy C, Patil MB, Kumar R, Patil S. 2009. Preliminary phytochemical investigation and wound healing activity of Allium Cepa Linn (Lilliacea). Int J Pharmacy and Pharm Sci. 2(2):167–176.
  • Shukr MH, Ismail S, Ahmed SM. 2019. Development and optimization of ezetimibe nanoparticles with improved antihyperlipidemic activity. J Drug Deliv Sci Technol. 49:383–395.
  • Surya S, Arun Kumar R, Carla B, Sunil C. 2017. Antihyperlipidemic effect of Ficus dalhousiae miq. stem bark on Triton WR-1339 and high fat diet-induced hyperlipidemic rats. Bull Fac Pharm Cairo Univ. 55:73–77.
  • Uchida A, Tao K, Ogihara J, Matsufuji H, Ohta S, Sakuraiet H. 2008. Effects of jumbo leek on blood glucose level in streptozotocin-induced diabetic rats and liver damage in acetaminophen-treated rats. Nippon Shokuhin Kagaku Kogaku Kaishi. 55(11):549–558.
  • Vargas JI, Arrese M, Shah VH, Arab JP. 2017. Use of statins in patients with chronic liver disease and cirrhosis: current views and prospects. Curr Gastroenterol Rep. 19(9):43.
  • Vedder H, Anthes N, Stumm G, Würz C, Behl C, Krieg JC. 1999. Estrogen hormones reduce lipid peroxidation in cells and tissues of the central nervous system. J Neurochem. 72(6):2531–2538.
  • Victor Antony Santiago J, Jayachitra J, Shenbagam M, Nalini N. 2012. Dietary d-limonene alleviates insulin resistance and oxidative stress-induced liver injury in high-fat diet and L-NAME-treated rats. Eur J Nutr. 51(1):57–68.
  • Vidyavati HG, Manjunatha H, Hemavathy J, Srinivasan K. 2010. Hypolipidemic and antioxidant efficacy of dehydrated onion in experimental rats. J Food Sci Technol. 47:55–60.
  • Wilkes JJ, Bonen A, Bell RC. 1998. A modified high-fat diet induces insulin resistance in rat skeletal muscle but not adipocytes. Am J Physiol. 275(4):E679–E686.
  • Xiao DH, Pinto JT, Gundersen GG, Weinstein IB. 2005. Effects of a series of organosulfur compounds on mitotic arrest and induction of apoptosis in colon cancer cells. Mol Cancer Ther. 4:1388–1398.
  • Yu FR, Lian XZ, Guo HY, McGuire PM, Li R, Wang R, Yu F. 2005. Isolation and characterization of methyl esters and derivatives from Euphorbia kansui (Euphorbiaceae) and their inhibitory effects on the human SGC-7901 cells. J Pharm Pharm Sci. 8(3):528–535.