MiR-377 accelerates cardiac hypertrophy by inhibiting autophagy via targeting PPARγ

References

• Ahmed FE, Ahmed NC, Vos PW, Bonnerup C, Atkins JN, Casey M, Nuovo GJ, Naziri W, Wiley JE, Mota H, et al. 2013. Diagnostic microRNA markers to screen for sporadic human colon cancer in stool: I. Proof of principle. Cancer Genomics Proteomics. 10(3):93–113.
   PubMed Web of Science ®Google Scholar
• Banerjee I, Fuseler JW, Price RL, Borg TK, Baudino TA. 2007. Determination of cell types and numbers during cardiac development in the neonatal and adult rat and mouse. Am J Physiol Heart Circ Physiol. 293(3):H1883–H1891.
   PubMed Web of Science ®Google Scholar
• Barger PM, Kelly DP. 2000. PPAR signaling in the control of cardiac energy metabolism. Trends Cardiovasc Med. 10(6):238–245.
   PubMed Web of Science ®Google Scholar
• Berlo JH, Van, Marjorie M, Molkentin JD. 2013. Signaling effectors underlying pathologic growth and remodeling of the heart. J Clin Invest. 123(1):37–45.
   Web of Science ®Google Scholar
• Bushati N, Cohen SM. 2007. microRNA functions. Annu Rev Cell Dev Biol. 23:175–205.
   PubMed Web of Science ®Google Scholar
• Calin GA, Croce CM. 2006. MicroRNA-cancer connection: the beginning of a new tale. Cancer Res. 66(15):7390–7394.
   PubMed Web of Science ®Google Scholar
• Callis TE, Pandya K, Seok HY, Tang RH, Tatsuguchi M, Huang ZP, Chen JF, Deng Z, Gunn B, Shumate J, et al. 2009. MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest. 119(9):2772–2786.
   PubMed Web of Science ®Google Scholar
• Campard D, Vasse M, Rose-John S, Poyer F, Lamacz M, Vannier JP. 2006. Multilevel regulation of IL-6R by IL-6-sIL-6R fusion protein according to the primitiveness of peripheral blood-derived CD133+ cells. Stem Cells. 24(5):1302–1314.
   Web of Science ®Google Scholar
• Cao DJ, Wang ZV, Battiprolu PK, Jiang N, Morales CR, Kong Y, Rothermel BA, Gillette TG, Hill JA. 2011. Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy. Proc Natl Acad Sci U S A. 108(10):4123–4128.
   PubMed Web of Science ®Google Scholar
• Cheng Y, Ji R, Yue J, Yang J, Liu X, Chen H, Dean DB, Zhang C. 2007. MicroRNAs are aberrantly expressed in hypertrophic heart: do they play a role in cardiac hypertrophy? Am J Pathol. 170(6):1831–1840.
   PubMed Web of Science ®Google Scholar
• Duan LJ, Ding M, Hou LJ, Cui YT, Li CJ, Yu DM. 2017. Long noncoding RNA TUG1 alleviates extracellular matrix accumulation via mediating microRNA-377 targeting of PPARgamma in diabetic nephropathy. Biochem Biophys Res Commun. 484(3):598–604.
   PubMed Web of Science ®Google Scholar
• Duan SZ, Ivashchenko CY, Russell MW, Milstone DS, Mortensen RM. 2005. Cardiomyocyte-specific knockout and agonist of peroxisome proliferator-activated receptor-gamma both induce cardiac hypertrophy in mice. Circ Res. 97(4):372–379.
   Web of Science ®Google Scholar
• Efeyan A, Comb WC, Sabatini DM. 2015. Nutrient-sensing mechanisms and pathways. Nature. 517(7534):302–310.
   PubMed Web of Science ®Google Scholar
• Esteller M. 2011. Non-coding RNAs in human disease. Nat Rev Genet. 12(12):861–874.
   PubMed Web of Science ®Google Scholar
• Formosa A, Markert EK, Lena AM, Italiano D, Finazzi-Agro E, Levine AJ, Bernardini S, Garabadgiu AV, Melino G, Candi E. 2014. MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells. Oncogene. 33(44):5173–5182.
   PubMed Web of Science ®Google Scholar
• Gómez-Hurtado N, Domínguez-Rodríguez A, Mateo P, Fernandez-Velasco M, Val-Blasco A, Aizpún R, Sabourin J, Gómez AM, Benitah JP, Delgado C. 2017. Beneficial effects of leptin treatment in a setting of cardiac dysfunction induced by transverse aortic constriction in mouse. J Physiol. 595(13):4227–4243.
   PubMed Web of Science ®Google Scholar
• Gottlieb RA, Mentzer RM. 2010. Autophagy during cardiac stress: joys and frustrations of autophagy. Annu Rev Physiol. 72:45–59.
   PubMed Web of Science ®Google Scholar
• Green DR, Beth L. 2014. To be or not to be? How selective autophagy and cell death govern cell fate. Cell. 157(1):65–75.
   PubMed Web of Science ®Google Scholar
• Guo Y, Chen Z, Zhang L, Zhou F, Shi S, Feng X, Li B, Meng X, Ma X, Luo M, et al. 2008. Distinctive microRNA profiles relating to patient survival in esophageal squamous cell carcinoma. Cancer Res. 68(1):26–33.
   PubMed Web of Science ®Google Scholar
• Han Y, Chen J, Zhao X, Liang C, Wang Y, Sun L, Jiang Z, Zhang Z, Yang R, Chen J, et al. 2011. MicroRNA expression signatures of bladder cancer revealed by deep sequencing. PLoS One. 6(3):e18286.
   PubMed Web of Science ®Google Scholar
• Hinrichs S, Heger J, Schreckenberg R, Wenzel S, Euler G, Arens C, Bader M, Rosenkranz S, Caglayan E, Schluter KD. 2011. Controlling cardiomyocyte length: the role of renin and PPAR-γ. Cardiovasc Res. 89(2):344–352.
   Web of Science ®Google Scholar
• Kamo T, Akazawa H, Komuro I. 2015. Cardiac nonmyocytes in the hub of cardiac hypertrophy. Circ Res. 117(1):89–98.
   Web of Science ®Google Scholar
• Kim I, Rodriguez-Enriquez S, Lemasters JJ. 2007. Selective degradation of mitochondria by mitophagy. Arch Biochem Biophys. 462(2):245–253.
   PubMed Web of Science ®Google Scholar
• Klionsky DJ, Emr SD. 2000. Autophagy as a regulated pathway of cellular degradation. Science. 290(5497):1717–1721.
   PubMed Web of Science ®Google Scholar
• Lee CH, Olson P, Evans RM. 2003. Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors. Endocrinology. 144(6):2201–2207.
   PubMed Web of Science ®Google Scholar
• Levine B, Kroemer G. 2008. Autophagy in the pathogenesis of disease. Cell. 132(1):27–42.
   PubMed Web of Science ®Google Scholar
• Li Z, Wang J, Yang X. 2015. Functions of autophagy in pathological cardiac hypertrophy. Int J Biol Sci. 11(6):672–678.
   PubMed Web of Science ®Google Scholar
• Schultz NA, Dehlendorff C, Jensen BV, Bjerregaard JK, Nielsen KR, Bojesen SE, Calatayud D, Nielsen SE, Yilmaz M, Hollander NH, et al. 2014. MicroRNA biomarkers in whole blood for detection of pancreatic cancer. JAMA. 311(4):392–404.
   PubMed Web of Science ®Google Scholar
• Son NH, Park TS, Yamashita H, Yokoyama M, Huggins LA, Okajima K, Homma S, Szabolcs MJ, Huang LS, Goldberg IJ. 2007. Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice. J Clin Invest. 117(10):2791–2801.
   Web of Science ®Google Scholar
• Staels B, Fruchart JC. 2005. Therapeutic roles of peroxisome proliferator-activated receptor agonists. Diabetes. 54(8):2460–2470.
   PubMed Web of Science ®Google Scholar
• Tan WS, Mullins TP, Flint M, Walton SL, Bielefeldt-Ohmann H, Carter DA, Gandhi MR, McDonald HR, Li J, Moritz KM, et al. 2018. Modeling heart failure risk in diabetes and kidney disease: limitations and potential applications of transverse aortic constriction in high-fat-fed mice. Am J Physiol Regul Integr Comp Physiol. 314(6):R858–R869.
   Web of Science ®Google Scholar
• Tirziu D, Simons M. 2009. Endothelium as master regulator of organ development and growth. Vascul Pharmacol. 50(1–2):1–7.
   Web of Science ®Google Scholar
• Ucar A, Gupta SK, Fiedler J, Erikci E, Kardasinski M, Batkai S, Dangwal S, Kumarswamy R, Bang C, Holzmann A, et al. 2012. The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy. Nat Commun. 3:1078.
   PubMed Web of Science ®Google Scholar
• Weiss CS, Hagenmuller M, Pichler M, Munz S, Ochs M, Buss SJ, Bekeredjian R, Katus HA, Hardt SE. 2010. Activation of PPARgamma by pioglitazone does not attenuate left ventricular hypertrophy following aortic banding in rats. Naunyn Schmiedebergs Arch Pharmacol. 381(4):285–295.
   Web of Science ®Google Scholar
• Xue R, Zeng J, Chen Y, Chen C, Tan W, Zhao J, Dong B, Sun Y, Dong Y, Liu C. 2017. Sestrin 1 ameliorates cardiac hypertrophy via autophagy activation. J Cell Mol Med. 21(6):1193–1205.
   Web of Science ®Google Scholar
• Yuan S, Jin J, Chen L, Hou Y, Wang H. 2017. Naoxintong/PPARgamma signaling inhibits cardiac hypertrophy via activation of autophagy. Evid Based Complement Alternat Med. 2017:3801976.
   PubMed Web of Science ®Google Scholar
• Zamore PD, Haley B. 2005. Ribo-gnome: the big world of small RNAs. Science. 309(5740):1519–1524.
   PubMed Web of Science ®Google Scholar
• Zhang R, Luo H, Wang S, Chen W, Chen Z, Wang HW, Chen Y, Yang J, Zhang X, Wu W, et al. 2014. MicroRNA-377 inhibited proliferation and invasion of human glioblastoma cells by directly targeting specificity protein 1. Neuro Oncol. 16(11):1510–1522.
   PubMed Web of Science ®Google Scholar
• Zhou LY, Liu JP, Wang K, Gao J, Ding SL, Jiao JQ, Li PF. 2013. Mitochondrial function in cardiac hypertrophy. Int J Cardiol. 167(4):1118–1125.
   Web of Science ®Google Scholar
• Zhu W, He J, Chen D, Zhang B, Xu L, Ma H, Liu X, Zhang Y, Le H. 2014. Expression of miR-29c, miR-93, and miR-429 as potential biomarkers for detection of early stage non-small lung cancer. PLoS One. 9(2):e87780.
   PubMed Web of Science ®Google Scholar