References
- Bo H, Fan L, Gong Z, Liu Z, Shi L, Guo C, Li X, Liao Q, Zhang W, Zhou M, Xiang B. 2019. Upregulation and hypomethylation of lncRNA AFAP1AS1 predicts a poor prognosis and promotes the migration and invasion of cervical cancer. Oncol Rep. 41(4):2431–2439. Available from: https://www.ncbi.nlm.nih.gov/pubmed/30816545. doi:10.3892/or.2019.7027.
- Casali PG, Abecassis N, Bauer S, Biagini R, Bielack S, Bonvalot S, Boukovinas I, Bovee JVMG, Brodowicz T, Broto JM, et al. 2018. Gastrointestinal stromal tumours: ESMO-EURACAN clinical Practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 29(Suppl 4):iv68–iv78. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29846513. doi:10.1093/annonc/mdy095.
- Cheetham SW, Gruhl F, Mattick JS, Dinger ME. 2013. Long noncoding RNAs and the genetics of cancer. Br J Cancer. 108(12):2419–2425. Available from: https://www.ncbi.nlm.nih.gov/pubmed/23660942. doi:10.1038/bjc.2013.233.
- Cho SW, Xu J, Sun R, Mumbach MR, Carter AC, Chen YG, Yost KE, Kim J, He J, Nevins SA, et al. 2018. Promoter of lncRNA Gene PVT1 is a tumor-suppressor DNA boundary element. Cell. 173(6):1398–1412.e22. e1322. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29731168. doi:10.1016/j.cell.2018.03.068.
- Connolly EM, Gaffney E, Reynolds JV. 2003. Gastrointestinal stromal tumours. Br J Surg. 90(10):1178–1186. Available from: https://www.ncbi.nlm.nih.gov/pubmed/14515284. doi:10.1002/bjs.4352.
- Consortium EP. 2012. An integrated encyclopedia of DNA elements in the human genome. Nature. 489(7414):57–74. Available from: https://www.ncbi.nlm.nih.gov/pubmed/22955616. doi:10.1038/nature11247.
- DeMatteo RP, Lewis JJ, Leung D, Mudan SS, Woodruff JM, Brennan MF. 2000. Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival. Ann Surg. 231(1):51–58. Available from: https://www.ncbi.nlm.nih.gov/pubmed/10636102. doi:10.1097/00000658-200001000-00008.
- Ding H, Liu J, Liu B, Zeng Y, Chen P, Su Y. 2018. Long noncoding RNA PVT1 inhibits interferon-α mediated therapy for hepatocellular carcinoma cells by interacting with signal transducer and activator of transcription 1. Biochem Biophys Res Commun. 500(4):973–980. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29715456. doi:10.1016/j.bbrc.2018.04.219.
- Endo H, Shiroki T, Nakagawa T, Yokoyama M, Tamai K, Yamanami H, Fujiya T, Sato I, Yamaguchi K, Tanaka N, et al. 2013. Enhanced expression of long Non-coding RNA HOTAIR Is associated with the development of gastric cancer. PLoS One. 8(10):e77070. Available from: <Go to ISI>://WOS:000325814200054. doi:ARTN e7707010.1371/journal.pone.0077070.
- Fan C, Tang Y, Wang J, Wang Y, Xiong F, Zhang S, Li X, Xiang B, Wu X, Guo C, et al. 2019. Long non-coding RNA LOC284454 promotes migration and invasion of nasopharyngeal carcinoma via modulating the Rho/Rac signaling pathway. Carcinogenesis. 40(2):380–391. Available from: https://www.ncbi.nlm.nih.gov/pubmed/30380023. doi:10.1093/carcin/bgy143.
- Ferretti C, Bruni L, Dangles-Marie V, Pecking AP, Bellet D. 2006. Molecular circuits shared by placental and cancer cells, and their implications in the proliferative, invasive and migratory capacities of trophoblasts. Hum Reprod Update. 13(2):121–141. Available from: https://www.ncbi.nlm.nih.gov/pubmed/17068222. doi:10.1093/humupd/dml048.
- Fletcher CDM, Berman JJ, Corless C, Gorstein F, Lasota J, Longley BJ, Miettinen M, O'Leary TJ, Remotti H, Rubin BP, et al. 2002. Diagnosis of gastrointestinal stromal tumors: a consensus approach. Int J Surg Pathol. 10(2):81–89. Available from: https://www.ncbi.nlm.nih.gov/pubmed/12075401. doi:10.1177/106689690201000201.
- Fukumura D, Gohongi T, Kadambi A, Izumi Y, Ang J, Yun C-O, Buerk DG, Huang PL, Jain RK. 2001. Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability. Proc Natl Acad Sci USA. 98(5):2604–2609. Available from: https://www.ncbi.nlm.nih.gov/pubmed/11226286. doi:10.1073/pnas.041359198.
- Guertin DA, Stevens DM, Thoreen CC, Burds AA, Kalaany NY, Moffat J, Brown M, Fitzgerald KJ, Sabatini DM. 2006. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCα, but Not S6K1. Dev Cell. 11(6):859–871. doi:10.1016/j.devcel.2006.10.007.
- Guo K, Yao J, Yu Q, Li Z, Huang H, Cheng J, Wang Z, Zhu Y. 2017. The expression pattern of long non-coding RNA PVT1 in tumor tissues and in extracellular vesicles of colorectal cancer correlates with cancer progression. Tumor Biol. 39(4). Available from: <Go to ISI>://WOS:000400268800073. doi:Artn 699122 10.1177/1010428317699122.
- He Y, Jing Y, Wei F, Tang Y, Yang L, Luo J, Yang P, Ni Q, Pang J, Liao Q, et al. 2018. Long non-coding RNA PVT1 predicts poor prognosis and induces radioresistance by regulating DNA repair and cell apoptosis in nasopharyngeal carcinoma. Cell Death Dis. 9(2):235. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29445147. doi:10.1038/s41419-018-0265-y.
- Hemming ML, Lawlor MA, Andersen JL, Hagan T, Chipashvili O, Scott TG, Raut CP, Sicinska E, Armstrong SA, Demetri GD, Bradner JE. 2019. Enhancer Domains in gastrointestinal stromal tumor regulate KIT expression and Are Targetable by BET Bromodomain inhibition. Cancer Res. 79(5):994–1009. Available from: https://www.ncbi.nlm.nih.gov/pubmed/30630822. doi:10.1158/0008-5472.CAN-18-1888.
- Hirota S, Isozaki K, Moriyama Y, Hashimoto K, Nishida T, Ishiguro S, Kawano K, Hanada M, Kurata A, Takeda M, Tunio GM. 1998. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science. 279(5350):577–580. Available from: https://www.ncbi.nlm.nih.gov/pubmed/9438854. doi:10.1126/science.279.5350.577.
- Hirota S, Ohashi A, Nishida T, Isozaki K, Kinoshita K, Shinomura Y, Kitamura Y. 2003. Gain-of-function mutations of platelet-derived growth factor receptor α gene in gastrointestinal stromal tumors. Gastroenterology. 125(3):660–667. Available from: https://www.ncbi.nlm.nih.gov/pubmed/12949711. doi:10.1016/s0016-5085(03)01046-1.
- Hu Y, Wang J, Qian J, Kong X, Tang J, Wang Y, Chen H, Hong J, Zou W, Chen Y, et al. 2014. Long noncoding RNA GAPLINC regulates CD44-dependent cell invasiveness and associates with poor prognosis of gastric cancer. Cancer Res. 74(23):6890–6902. Available from: https://www.ncbi.nlm.nih.gov/pubmed/25277524. doi:10.1158/0008-5472.CAN-14-0686.
- Huang F, Chen W, Peng J, Li Y, Zhuang Y, Zhu Z, Shao C, Yang W, Yao H, Zhang S. 2018. LncRNA PVT1 triggers Cyto-protective autophagy and promotes pancreatic ductal adenocarcinoma development via the miR-20a-5p/ULK1 Axis. Mol Cancer. 17(1):98. Available from: https://www.ncbi.nlm.nih.gov/pubmed/30001707. doi:10.1186/s12943-018-0845-6.
- Huang T, Liu HW, Chen JQ, Wang SH, Hao LQ, Liu M, Wang B. 2017. The long noncoding RNA PVT1 functions as a competing endogenous RNA by sponging miR-186 in gastric cancer. Biomed Pharmacother. 88:302–308. Available from: <Go to ISI>://WOS:000395528000035. doi:10.1016/j.biopha.2017.01.049.
- Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B. 2006. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell. 127(1):125–137. doi:10.1016/j.cell.2006.08.033.
- Jia X, Chen J, Megger DA, Zhang X, Kozlowski M, Zhang L, Fang Z, Li J, Chu Q, Wu M, et al. 2017. Label-free proteomic analysis of exosomes derived from inducible hepatitis B virus-replicating HepAD38 cell line. Mol Cell Proteomics. 16(4 suppl 1):S144. Available from: http://www.mcponline.org/content/16/4_suppl_1/S144.abstract. doi:10.1074/mcp.M116.063503.
- Li H, Han L, Yang Z, Huang W, Zhang X, Gu Y, Li Y, Liu X, Zhou L, Hu J, et al. 2015. Differential Proteomic analysis of syncytiotrophoblast extracellular vesicles from early-onset severe preeclampsia, using 8-Plex iTRAQ labeling coupled with 2D Nano LC-MS/MS. Cell Physiol Biochem. 36(3):1116–1130. Available from: https://www.ncbi.nlm.nih.gov/pubmed/26113202. doi:10.1159/000430283.
- Li F, Huynh H, Li X, Ruddy DA, Wang Y, Ong R, Chow P, Qiu S, Tam A, Rakiec DP, et al. 2015. FGFR-Mediated Reactivation of MAPK signaling attenuates antitumor effects of Imatinib in gastrointestinal stromal tumors. Cancer Discov. 5(4):438–451. Available from: https://www.ncbi.nlm.nih.gov/pubmed/25673643. doi:10.1158/2159-8290.CD-14-0763.
- Li H, Yu B, Li J, Su L, Yan M, Zhang J, Li C, Zhu Z, Liu B. 2015. Characterization of differentially expressed genes involved in pathways associated with gastric cancer. PLoS One. 10(4):e0125013. Available from: https://www.ncbi.nlm.nih.gov/pubmed/25928635. doi:10.1371/journal.pone.0125013.
- Lian Y, Xiong F, Yang L, Bo H, Gong Z, Wang Y, Wei F, Tang Y, Li X, Liao Q, et al. 2018. Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway. J Exp Clin Cancer Res. 37(1):253. Available from: https://www.ncbi.nlm.nih.gov/pubmed/30326930. doi:10.1186/s13046-018-0918-9.
- Liang Y, Song X, Li Y, Su P, Han D, Ma T, Guo R, Chen B, Zhao W, Sang Y, et al. 2019. circKDM4C suppresses tumor progression and attenuates doxorubicin resistance by regulating miR-548p/PBLD axis in breast cancer. Oncogene. 38(42):6850–6866. Available from: https://doi.org/10.1038/s41388-019-0926-z. doi:10.1038/s41388-019-0926-z.
- Liu B, Pan CF, Yao GL, Wei K, Xia Y, Chen YJ. 2018. The long non-coding RNA AK001796 contributes to tumor growth via regulating expression of p53 in esophageal squamous cell carcinoma. Cancer Cell Int. 18:38. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29568233. doi:10.1186/s12935-018-0537-8.
- Liu Z, Zhang H. 2017. LncRNA plasmacytoma variant translocation 1 is an oncogene in bladder urothelial carcinoma. Oncotarget. 8(38):64273–64282. Available from: https://www.ncbi.nlm.nih.gov/pubmed/28969069. doi:10.18632/oncotarget.19604.
- Milhem M, Deutsch JM. 2015. Imatinib Dosing in gastrointestinal stromal tumors (GISTs): when, How Much, and How long? Curr Clin Pharmacol. 10(4):311–320. Available from: https://www.ncbi.nlm.nih.gov/pubmed/26548908. doi:10.2174/1574884710666151020100518.
- Peterson TR, Laplante M, Thoreen CC, Sancak Y, Kang SA, Kuehl WM, Gray NS, Sabatini DM. 2009. DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival. Cell. 137(5):873–886. doi:10.1016/j.cell.2009.03.046.
- Pickard MR, Mourtada-Maarabouni M, Williams GT. 2013. Long non-coding RNA GAS5 regulates apoptosis in prostate cancer cell lines. Biochimica et Biophysica Acta (BBA) - Mol Basis Dis. 1832(10):1613–1623. Available from: https://www.ncbi.nlm.nih.gov/pubmed/23676682. doi:10.1016/j.bbadis.2013.05.005.
- Ping GF, Xiong WC, Zhang LF, Li YR, Zhang YS, Zhao YL. 2018. Silencing long noncoding RNA PVT1 inhibits tumorigenesis and cisplatin resistance of colorectal cancer. Am J Transl Res. 10(1):138. Available from: <Go to ISI>://WOS:000425213900012.
- Qi B, Wang Y, Chen Z-J, Li X-N, Qi Y, Yang Y, Cui G-H, Guo H-Z, Li W-H, Zhao S. 2017. Down-regulation of miR-30a-3p/5p promotes esophageal squamous cell carcinoma cell proliferation by activating the Wnt signaling pathway. World J Gastroenterol. 23(45):7965–7977. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29259372. doi:10.3748/wjg.v23.i45.7965.
- Sang Y, Chen B, Song X, Li Y, Liang Y, Han D, Zhang N, Zhang H, Liu Y, Chen T, et al. 2019. circRNA_0025202 regulates Tamoxifen sensitivity and tumor progression via regulating the miR-182-5p/FOXO3a Axis in breast cancer. Mol Ther. 27(9):1638–1652. doi:10.1016/j.ymthe.2019.05.011.
- Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. 2005. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science. 307(5712):1098–1101. doi:10.1126/science.1106148.
- Shao Y, Ye M, Jiang X, Sun W, Ding X, Liu Z, Ye G, Zhang X, Xiao B, Guo J. 2014. Gastric Juice long Noncoding RNA used as a tumor Marker for Screening gastric cancer. Cancer. 120(21):3320–3328. Available from:<Go to ISI>://WOS:000344164100011. doi:10.1002/cncr.28882.
- Shen SN, Li K, Liu Y, Yang CL, He CY, Wang HR. 2019. Down-regulation of long noncoding RNA PVT1 inhibits esophageal carcinoma cell migration and invasion and promotes cell apoptosis via microRNA-145-mediated inhibition of FSCN1. Mol Oncol. 13(12):2554–2573. Available from: <Go to ISI>://WOS:000485575400001. doi:10.1002/1878-0261.12555.
- Soreide K, Sandvik OM, Soreide JA, Giljaca V, Jureckova A, Bulusu VR. 2016. Global epidemiology of gastrointestinal stromal tumours (GIST): A systematic review of population-based cohort studies. Cancer Epidemiol. 40:39–46. Available from: https://www.ncbi.nlm.nih.gov/pubmed/26618334. doi:10.1016/j.canep.2015.10.031.
- von Mehren M, Randall RL, Benjamin RS, Boles S, Bui MM, Ganjoo KN, George S, Gonzalez RJ, Heslin MJ, Kane JM, et al. 2018. Soft Tissue sarcoma, version 2.2018, NCCN clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 16(5):536–563. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29752328. doi:10.6004/jnccn.2018.0025.
- Wei F, Jing Y-Z, He Y, Tang Y-Y, Yang L-T, Wu Y-F, Tang L, Shi L, Gong Z-J, Guo C, et al. 2019. Cloning and characterization of the putative AFAP1-AS1 promoter region. J Cancer. 10(5):1145–1153. Available from: https://www.ncbi.nlm.nih.gov/pubmed/30854123. doi:10.7150/jca.29049.
- Wilusz JE, Sunwoo H, Spector DL. 2009. Long noncoding RNAs: functional surprises from the RNA world. Genes Dev. 23(13):1494–1504. Available from: https://www.ncbi.nlm.nih.gov/pubmed/19571179. doi:10.1101/gad.1800909.
- Wu DP, Li Y, Zhang HX, Hu XG. 2017. Knockdown of lncrna PVT1 enhances Radiosensitivity in Non-small cell lung cancer by Sponging Mir-195. Cell Physiol Biochem. 42(6):2453–2466. Available from:<Go to ISI>://WOS:000415239800026. doi:10.1159/000480209.
- Yang X, Chen Y, Chen L. 2017. The Versatile role of microRNA-30a in human cancer. Cell Physiol Biochem. 41(4):1616–1632. Available from: https://www.ncbi.nlm.nih.gov/pubmed/28359057. doi:10.1159/000471111.
- Zeidler R, Lipp M, Joos S, Delecluse H-J, Bornkamm GW, Klobeck G, Vuillaume M, Lenoir GM. 1994. Breakpoints of Burkitt's lymphoma t(8;22) translocations map within a distance of 300 kb downstream of MYC. Genes Chromosomes Cancer. 9(4):282–287. Available from: https://www.ncbi.nlm.nih.gov/pubmed/7519050. doi:10.1002/gcc.2870090408.
- Zhao L, Kong H, Sun H, Chen Z, Chen B, Zhou M. 2018. LncRNA-PVT1 promotes pancreatic cancer cells proliferation and migration through acting as a molecular sponge to regulate miR-448. J Cell Physiol. 233(5):4044–4055. Available from: https://www.ncbi.nlm.nih.gov/pubmed/28657147. doi:10.1002/jcp.26072.
- Zhu S, Mao J, Shao Y, Chen F, Zhu X, Xu D, Zhang X, Guo J. 2015. Reduced expression of the long non-coding RNA AI364715 in gastric cancer and its clinical significance. Tumour Biol. 36(10):8041–8045. Available from: https://www.ncbi.nlm.nih.gov/pubmed/25971582. doi:10.1007/s13277-015-3543-7.