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Pharmacology & Pharmaceutics

Impact of gargling on respiratory infections

Pages 147-158 | Received 13 Nov 2020, Accepted 17 Feb 2021, Published online: 03 Mar 2021

References

  • Agarwal A, Gupta D, Yadav G, Goyal P, Singh PK, Singh U. 2009. An evaluation of the efficacy of licorice gargle for attenuating postoperative sore throat: a prospective, randomized, single-blind study. Anesth Analg. 109(1):77–81.
  • Agarwal A, Nath SS, Goswami D, Gupta D, Dhiraaj S, Singh PK. 2006. An evaluation of the efficacy of aspirin and benzydamine hydrochloride gargle for attenuating postoperative sore throat: a prospective, randomized, single-blind study. Anesth Analg. 103(4):1001–1003.
  • Ajello M, Greco R, Giansanti F, Massucci MT, Antonini G, Valenti P. 2002. Anti-invasive activity of bovine lactoferrin towards group A streptococci. Biochem Cell Biol. 80(1):119–124.
  • Alshehri FA. 2018. The use of mouthwash containing essential oils (LISTERINE) to improve oral health: a systematic review. Saudi Dent J. 30(1):2–6.
  • American Dental Association. 2019, August 29. Oral Health Topics, Mouthwash (Mouthrinse). from https://www.ada.org/en/member-center/oral-health-topics/mouthrinse.
  • Aydın GB, Ergil J, Polat R, Sayın M, Akelma FK. 2014. Comparison of Siccoral spray, Stomatovis gargle, and Strefen lozenges on postoperative sore throat. J Anesth. 28(4):494–498.
  • Basrani B. 2005. Chlorhexidine gluconate. Aust Endod J. 31(2):48–52.
  • Bastos VP, Gomes AS, Lima FJB, Brito TS, Soares PMG, Pinho JPM, Silva CS, Santos AA, Souza MHLP, Magalhães PJC. 2011. Inhaled 1, 8-cineole reduces inflammatory parameters in airways of Ovalbumin-challenged Guinea Pigs. Basic Clin Pharmacol Toxicol. 108(1):34–39.
  • Bellissimo-Rodrigues F, Bellissimo-Rodrigues WT, Viana JM, Teixeira GCA, Nicolini E, Auxiliadora-Martins M, Passos ADC, Martinez EZ, Basile-Filho A, Martinez R. 2009. Effectiveness of oral rinse with chlorhexidine in preventing nosocomial respiratory tract infections among intensive care unit patients. Infection Control Hosp Epidemiol. 30(10):952–958.
  • Berlutti F, Pantanella F, Natalizi T, Frioni A, Paesano R, Polimeni A, Valenti P. 2011. Antiviral properties of lactoferrin – a natural immunity molecule. Molecules. 16(8):6992–7018.
  • Bernstein D, Schiff G, Echler G, Prince A, Feller M, Briner W. 1990. In vitro virucidal effectiveness of a 0.12%-chlorhexidine gluconate mouthrinse. J Dent Res. 69(3):874–876.
  • Block MS, Rowan BG. 2020. Hypochlorous acid – a review. J Oral Maxillofac Surg. 78(9):1461–1466.
  • Cai Z-M, Peng J-Q, Chen Y, Tao L, Zhang Y-Y, FuL-Y, Long Q-D, Shen X-C. 2020. 1, 8-Cineole: a review of source, biological activities, and application. J Asian Nat Prod Res. 1–17. doi:10.1080/10286020.2020.1839432
  • Canbay O, Celebi N, Sahin A, Celiker V, Ozgen S, Aypar U. 2008. Ketamine gargle for attenuating postoperative sore throat. Br J Anaesth. 100(4):490–493.
  • Chan L, Lee M, Lo YL. 2010. Postoperative sore throat and ketamine gargle. Br J Anaesth. 105(1):97.
  • Chow EP, Walker S, Hocking JS, Bradshaw CS, Chen MY, Tabrizi SN, Howden BP, Law MG, Maddaford K, Read TRH, et al. 2017. A multicentre double-blind randomised controlled trial evaluating the efficacy of daily use of antibacterial mouthwash against oropharyngeal gonorrhoea among men who have sex with men: the OMEGA (oral mouthwash use to eradicate GonorrhoeA) study protocol. BMC Infect Dis. 17(1):456.
  • Cinatl J, Morgenstern B, Bauer G, Chandra P, Rabenau H, Doerr HW. 2003. Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus. Lancet. 361(9374):2045–2046.
  • Cingi C, Songu M, Ural A, Yildirim M, Erdogmus N, Bal C. 2010. Effects of chlorhexidine/benzydamine mouth spray on pain and quality of life in acute viral pharyngitis: A prospective, randomized, double-blind, placebo-controlled, multicenter study. Ear Nose Throat J. 89(11):546–549.
  • Cingi C, Songu M, Ural A, Erdogmus N, Yildirim M, Cakli H, Bal C. 2011. Effect of chlorhexidine gluconate and benzydamine hydrochloride mouth spray on clinical signs and quality of life of patients with streptococcal tonsillopharyngitis: multicentre, prospective, randomised, double-blinded, placebo-controlled study. J Laryngol Otol. 125(6):620–625.
  • Corner A-M, Dolan MM, Yankell SL, Malamud D. 1988. C31g, a new agent for oral use with potent antimicrobial and antiadherence properties. Antimicrob Agents Chemother. 32(3):350–353.
  • Dennison DK, Meredith GM, et al. 1995. The antiviral spectrum of Listerine antiseptic. Oral Surg, Oral Med, Oral Pathol, Oral Radiol Endodontol. 79(4):442–448.
  • Eggers M. 2019. Infectious disease management and control with povidone iodine. Infect Dis Ther. 1–13.
  • Eggers M, Eickmann M, Zorn J. 2015. Rapid and effective virucidal activity of povidone-iodine products against Middle East respiratory syndrome coronavirus (MERS-CoV) and modified vaccinia virus Ankara (MVA). Infect Dis Ther. 4(4):491–501.
  • Eggers M, Koburger-Janssen T, Eickmann M, Zorn J. 2018. In vitro bactericidal and virucidal efficacy of Povidone-Iodine gargle/mouthwash against respiratory and oral tract pathogens. Infect Dis Ther. 7(2):249–259.
  • Franklin G-G, Klukowska MA, Zhang YH, Anastasia MK, Cheng R, Gabbard M, Coggan J, White DJ. 2014. Comparative bioavailability and antimicrobial activity of cetylpyridinium chloride mouthrinses in vitro and in vivo. Am J Dent. 27(4):185–190.
  • Fu J, Wei P, et al. 2014. In vitro antifungal effect and inhibitory activity on biofilm formation of seven commercial mouthwashes. Oral Dis. 20(8):815–820.
  • Furushima D, Ide K, Yamada H. 2018. Effect of tea catechins on influenza infection and the common cold with a focus on epidemiological/clinical studies. Molecules. 23(7):1795.
  • Goodall EC, Granados AC, Luinstra K, Pullenayegum E, Coleman BL, Loeb M, Smieja M. 2014. Vitamin D 3 and gargling for the prevention of upper respiratory tract infections: a randomized controlled trial. BMC Infect Dis. 14(1):273.
  • Haffajee AD, Yaskell T, Socransky SS. 2008. Antimicrobial effectiveness of an herbal mouthrinse compared with an essential oil and a chlorhexidine mouthrinse. J Am Dent Assoc. 139(5):606–611.
  • Haps S, Slot D, Berchier CE, Van der Weijden GA. 2008. The effect of cetylpyridinium chloride-containing mouth rinses as adjuncts to toothbrushing on plaque and parameters of gingival inflammation: a systematic review. Int J Dent Hyg. 6(4):290–303.
  • Hendry E, Worthington T, Conway BR, Lambert PA. 2009. Antimicrobial efficacy of eucalyptus oil and 1, 8-cineole alone and in combination with chlorhexidine digluconate against microorganisms grown in planktonic and biofilm cultures. J Antimicrob Chemother. 64(6):1219–1225.
  • Herrera D, Santos S, Ferrus J, Barbieri G, Trombelli L, Sanz M. 2005. Efficacy of a 0.15% benzydamine hydrochloride and 0.05% cetylpyridinium chloride mouth rinse on 4-day de novo plaque formation. J Clin Periodontol. 32(6):595–603.
  • Higashiguchi T, Ohara H, Kamakura Y, Kikutani T, Kuzuya M, Enoki H, Sanada H, Matsuzaki M, Maruyama M. 2017. Efficacy of a new post-mouthwash intervention (wiping plus oral nutritional supplements) for preventing aspiration pneumonia in elderly people: a multicenter, randomized, comparative trial. Ann Nutr Metab. 71(3–4):253–260.
  • Hill DR, Newburg DS. 2015. Clinical applications of bioactive milk components. Nutr Rev. 73(7):463–476.
  • Honarmand A, Safavi M, Safaei Arani A, Shokrani O. 2016. The efficacy of different doses of liquorice gargling for attenuating postoperative sore throat and cough after tracheal intubation. Eur J Anaesthesiol. 33(8):595–596.
  • Hu R, Jiang X, Wu Y. 2013. Prospective trial finds nystatin mouthwash effective prophylaxis for pulmonary invasive fungal infections that originate in the throat of patients with hematologic malignancies. Neoplasma. 60(3):315–321.
  • Ide K, Yamada H, Matsushita K, Ito M, Nojiri K, Toyoizumi K, Matsumoto K, Sameshima Y. 2014. Effects of green tea gargling on the prevention of influenza infection in high school students: a randomized controlled study. PloS One. 9(5): e96373.
  • Ide K, Yamada H, Kawasaki Y. 2016. Effect of gargling with tea and ingredients of tea on the prevention of influenza infection: a meta-analysis. BMC Public Health. 16(1):396.
  • Ikeda M, Miki T, Atsumi M, Inagaki A, Mizuguchi E, Meguro M, Kanamori D, Nakagawa K, Watanabe R, Mano K, et al. 2014. Effective elimination of contaminants after oral care in elderly institutionalized individuals. Geriatr Nurs. 35(4):295–299.
  • Imanishi N, Tuji Y, Katada Y, Maruhashi M, Konosu S, Mantani N, Terasawa K, Ochiai H. 2002. Additional inhibitory effect of tea extract on the growth of influenza A and B viruses in MDCK cells. Microbiol Immunol. 46(7):491–494.
  • Ishikawa A, Yoneyama T, Hirota K, Miyake Y, Miyatake K. 2008. Professional oral health care reduces the number of oropharyngeal bacteria. J Dent Res. 87(6):594–598.
  • Ito H, Ito T, Hikida M, Yashiro J, Otsuka A, Kida H, Otsuki K. 2006. Outbreak of highly pathogenic avian influenza in Japan and anti-influenza virus activity of povidone-iodine products. Dermatology. 212(Suppl. 1):115–118.
  • Jácomo AD, Carmona F, Matsuno AK, Manso PH, Carlotti APCP. 2011. Effect of oral hygiene with 0.12% chlorhexidine gluconate on the incidence of nosocomial pneumonia in children undergoing cardiac surgery. Infect Control Hosp Epidemiol.. 32(6):591–596.
  • Jefferson T, Foxlee R, Mar CD, Dooley L, Ferroni E, Hewak B, Prabhala A, Nair S, Rivetti A. 2008. Physical interventions to interrupt or reduce the spread of respiratory viruses: systematic review. Br Med J. 336(7635):77–80.
  • Kitamura T, Satomura K, Kawamura T, Yamada S, Takashima K, Suganuma N, Namai H, Komura Y. 2007. Can we prevent influenza-like illnesses by gargling? Intern Med. 46(18):1623–1624.
  • Lee D-H, Youn H-N, Park J-K, Kang B-H, Kang J-H, Lee J-B, Park S-Y, Choi I-S, Lee S-W, Song C-S. 2014. In vitro virucidal effect of mouthrinse containing C31G on seasonal influenza viruses. J Microbiol Biotechnol. 24(7):921–924.
  • Liccardi G, Triggiani M, et al. 2003. Severe oral symptoms after the use of an oral solution containing ketoprofen in two NSAIDs-sensitive patients. J Investig Allergol Clin Immunol. 13(4):278–280.
  • Maeda K, Akagi J. 2014. Oral care may reduce pneumonia in the tube-fed elderly: a preliminary study. Dysphagia. 29(5):616–621.
  • Mandel ID. 1994. Antimicrobial mouthrinses: overview and update. J Am Dent Assoc. 125(8):2S–10S.
  • Matsumoto K, Yamada H, Takuma N, Niino H, Sagesaka YM. 2011. Effects of green tea catechins and theanine on preventing influenza infection among healthcare workers: a randomized controlled trial. BMC Complement Altern Med. 11(1):1–7.
  • McCoy LC, Wehler CJ, Rich SE, Garcia RI, Miller DR, Jones JA. 2008. Adverse events associated with chlorhexidine use: results from the Department of Veterans Affairs Dental Diabetes Study. J Am Dent Assoc. 139(2):178–183.
  • Meiller TF, Silva A, Ferreira SM, Jabra-Rizk MA, Kelley JI, DePaola LG. 2005. Efficacy of listerine antiseptic in reducing viral contamination of saliva. J Clin Periodontol. 32(4):341–346.
  • Mukherjee PK, Esper F, Buchheit K, Arters K, Adkins I, Ghannoum MA, Salata RA. 2017. Randomized, double-blind, placebo-controlled clinical trial to assess the safety and effectiveness of a novel dual-action oral topical formulation against upper respiratory infections. BMC Infect Dis. 17(1):74.
  • Nagatake T, Ahmed K, Oishi K. 2002. Prevention of respiratory infections by povidone-iodine gargle. Dermatology. 204(Suppl. 1):32–36.
  • Nazari S, Rameshrad M, Hosseinzadeh H. 2017. Toxicological effects of Glycyrrhiza glabra (licorice): a review. Phytother Res. 31(11):1635–1650.
  • Noda T, Ojima T, Hayasaka S, Murata C, Hagihara A. 2012. Gargling for oral hygiene and the development of fever in childhood: a population study in Japan. J Epidemiol. 22(1):45–49.
  • Nosulya E, Kim I, Chernykh NM, Karnoukhova OA. 2015. Acute tonsillopharyngitis: the effectiveness of topical therapy. Vestn Otorinolaringol. 80(5):71–76.
  • Ogata J, Minami K, Horishita T, Shiraishi M, Okamoto T, Terada T, Sata T. 2005. Gargling with sodium azulene sulfonate reduces the postoperative sore throat after intubation of the trachea. Anesth Analg. 101(1):290–293.
  • Ogata J, Minami K, Miyamoto H, Horishita T, Ogawa M, Sata T, Taniguchi H. 2004. Gargling with povidone-iodine reduces the transport of bacteria during oral intubation. Can J Anesth. 51(9):932–936.
  • Oh KE, Song AR, Sok SR. 2017. Effects of Aroma gargling, cold water gargling, and wet gauze application on thirst, halitosis, and sore throat of patients after spine surgery. Holist Nurs Pract. 31(4):253–259.
  • Paesano R, Torcia F, Berlutti F, Pacifici E, Ebano V, Moscarini M, Valenti P. 2006. Oral administration of lactoferrin increases hemoglobin and total serum iron in pregnant women. Biochem Cell Biol. 84(3):377–380.
  • Panchabhai TS, Dangayach NS. 2010. Oral cleansing with chlorhexidine to decrease the incidence of nosocomial pneumonia: using the right concentration in the right place. Infect Control Hosp Epidemiol. 31(4):429–429.
  • Panchabhai TS, Dangayach NS, Krishnan A, Kothari VM, Karnad DR. 2009. Oropharyngeal cleansing with 0.2% chlorhexidine for prevention of nosocomial pneumonia in critically ill patients: an open-label randomized trial with 0.01% potassium permanganate as control. Chest. 135(5):1150–1156.
  • Passàli D. 2001. Efficacy and safety of ketoprofen lysine salt mouthwash versus benzydamine hydrochloride mouthwash in acute pharyngeal inflammation: a randomized, single-blind study. Clin Ther. 23(9):1508–1518.
  • Phillips TR, Fairley C, Maddaford K, Trumpour S, Wigan R, Bradshaw C, Hocking JS, Chow EPF. 2020. Duration of gargling and rinsing among frequent mouthwash users: a cross-sectional study. BMJ Open. 10(9):e040754.
  • Prabuseenivasan S, Jayakumar M, Ignacimuthu S. 2006. In vitro antibacterial activity of some plant essential oils. BMC Complement Altern Med. 6(1):39.
  • Quagliarello V, Juthani-Mehta M, Ginter S, Towle V, Allore H, Tinetti M. 2009. Pilot testing of intervention protocols to prevent pneumonia in nursing home residents. J Am Geriatr Soc. 57(7):1226–1231.
  • Quane P, Graham G, Ziegler JB. 1998. Pharmacology of benzydamine. Inflammopharmacology. 6(2):95–107.
  • Radford J, Beighton D, Nugent Z, Jackson RJ. 1997. Effect of use of 0.05% cetylpyridinium chloride mouthwash on normal oral flora. J Dent. 25(1):35–40.
  • Ramalingam S, Cai B, et al. 2018. Antiviral innate immune response in non-myeloid cells is augmented by chloride ions via an increase in intracellular hypochlorous acid levels. Sci Rep. 8(1):1–11.
  • Ramalingam S, Graham C, Dove J, Morrice L, Sheikh A. 2019. A pilot, open labelled, randomised controlled trial of hypertonic saline nasal irrigation and gargling for the common cold. Sci Rep. 9(1):1–11.
  • Renzetti A, Betts JW, Fukumoto K, Rutherford RN. 2020. Antibacterial green tea catechins from a molecular perspective: mechanisms of action and structure–activity relationships. Food Funct. 11(11):9370–9396.
  • Robinson N, Scully C. 2016. Oral health: mouthwash abuse. Br Dent J. 221(6):280.
  • Rothberg MB, Haessler SD, Brown RB. 2008. Complications of viral influenza. Am J Med. 121(4):258–264.
  • Ruetzler K, Fleck M, Nabecker S, Pinter K, Landskron G, Lassnigg A, You J, Sessler Daniel I. 2013. A randomized, double-blind comparison of licorice versus sugar-water gargle for prevention of postoperative sore throat and postextubation coughing. Anesth Analg. 117(3):614–621.
  • Sakai M, Shimbo T, Omata K, Takahashi Y, Satomura K, Kitamura T, Kawamura T, Baba H, Yoshihara M, Itoh H. 2008. Cost-effectiveness of gargling for the prevention of upper respiratory tract infections. BMC Health Serv Res. 8(1):258.
  • Sato S, Miyake M, Hazama A, Omori K. 2014. Povidone-iodine-induced cell death in cultured human epithelial HeLa cells and rat oral mucosal tissue. Drug Chem Toxicol. 37(3):268–275.
  • Sato K, Ohmori T, Shiratori K, Yamazaki K, Yamada E, Kimura H, Takano K. 2007. Povidone iodine-induced overt hypothyroidism in a patient with prolonged habitual gargling: urinary excretion of iodine after gargling in normal subjects. Intern Med. 46(7):391–395.
  • Satomura K, Kitamura T, Kawamura T, Shimbo T, Watanabe M, Kamei M, Takano Y, Tamakoshi A. 2005. Prevention of upper respiratory tract infections by gargling: a randomized trial. Am J Prev Med. 29(4):302–307.
  • Schapowal A, Berger D, Klein P, Suter A. 2009. Echinacea/sage or chlorhexidine/lidocaine for treating acute sore throats: a randomized double-blind trial. Eur J Med Res. 14(9):406.
  • Scheibler E, Garcia MCR, Medina da Silva R, Figueiredo MA, Salum FG, Cherubini K. 2017. Use of nystatin and chlorhexidine in oral medicine: properties, indications and pitfalls with focus on geriatric patients. Gerodontology. 34(3):291–298.
  • Schreier H, Erdos G, Reimer K, König B, König W, Fleischer W. 1997. Molecular effects of povidone-iodine on relevant microorganisms: an electron-microscopic and biochemical study. Dermatology. 195(Suppl. 2):111–116.
  • Serra E, Hidalgo-Bastida LA, Verran J, Williams D, Malic S. 2018. Antifungal activity of commercial essential oils and biocides against Candida albicans. Pathogens. 7(1):15.
  • Sharif-Abdullah SSB, Chong MC, Surindar-Kaur SS, Kamaruzzaman SB, Ng KH. 2016. The effect of chlorhexidine in reducing oral colonisation in geriatric patients: a randomised controlled trial. Singapore Med J. 57(5):262.
  • Shillingburg A, Craig M, Kanate AS, Hamadani M, Cumpston A. 2016. Treatment of severe mucositis pain with oral Ketamine mouthwash. Biol Blood Marrow Transplant. 22(3):S479–S480.
  • Shirai J, Kanno T, Tsuchiya Y, Mitsubayashi S, Seki R. 2000. Effects of chlorine, iodine, and quaternary ammonium compound disinfectants on several exotic disease viruses. J Vet Med Sci. 62(1):85–92.
  • Shiraishi T, Nakagawa Y. 2002. Evaluation of the bactericidal activity of povidone-iodine and commercially available gargle preparations. Dermatology. 204(Suppl. 1):37–41.
  • Šlapak I, Skoupá J, Strnad P, Horník P. 2008. Efficacy of isotonic nasal wash (seawater) in the treatment and prevention of rhinitis in children. Arch Otolaryngol Head Neck Surg. 134(1):67–74.
  • Sreenivasan P, Haraszthy V, Zambon JJ. 2013. Antimicrobial efficacy of 0· 05% cetylpyridinium chloride mouthrinses. Lett Appl Microbiol. 56(1):14–20.
  • Steinmann J, Buer J, Pietschmann T, Steinmann E. 2013. Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea. Br J Pharmacol. 168(5):1059–1073.
  • Stoeken JE, Paraskevas S, van der Weijden GA. 2007. The long-term effect of a mouthrinse containing essential oils on dental plaque and gingivitis: a systematic review. J Periodontol. 78(7):1218–1228.
  • Suzuki T, Kataoka H, Ida T, Mikuniya T, Suzuki T, Kamachi K. 2012. Bactericidal activity of topical antiseptics and their gargles against Bordetella pertussis. J Infect Chemother. 18(2):272–275.
  • Takahashi S, Sato K, Kusaka Y, Hagihara A. 2017. Public preventive awareness and preventive behaviors during a major influenza epidemic in Fukui, Japan. J Infect Public Health. 10(5):637–643.
  • Tanaka Y, Kikuzaki H, Fukuda S, Nakatani N. 2001. Antibacterial compounds of licorice against upper airway respiratory tract pathogens. J Nutr Sci Vitaminol. 47(3):270–273.
  • Tano L, Tano K. 2004. A daily nasal spray with saline prevents symptoms of rhinitis. Acta Otolaryngol. 124(9):1059–1062.
  • Tashiro K, Katoh T, Yoshinari N, Hirai K, Andoh N, Makii K, Matsuo K, Ogasawara T. 2012. The short-term effects of various oral care methods in dependent elderly: comparison between toothbrushing, tongue cleaning with sponge brush and wiping on oral mucous membrane by chlorhexidine. Gerodontology. 29(2):e870–e882.
  • Troeger C, Blacker B, Khalil IA, Rao PC, Cao J, Zimsen SRM, Albertson SB, Deshpande A, Farag T, Abebe Z, et al. 2018. Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Infect Dis. 18(11):1191–1210.
  • Troeger CE, Blacker BF, Khalil IA, Zimsen SRM, Albertson SB, Abate D, Abdela J, Adhikari TB, Aghayan SA, Agrawal S, et al. 2019. Mortality, morbidity, and hospitalisations due to influenza lower respiratory tract infections, 2017: an analysis for the Global Burden of Disease Study 2017. Lancet Respir Med. 7(1):69–89.
  • Vlachojannis C, Chrubasik-Hausmann S, Hellwig E, Al-Ahmad A. 2015. A preliminary investigation on the antimicrobial activity of listerine, its components, and of mixtures thereof. Phytother Res. 29(10):1590–1594.
  • Vlachojannis C, Winsauer H, Chrubasik S. 2013. Effectiveness and safety of a mouthwash containing essential oil ingredients. Phytother Res. 27(5):685–691.
  • Wang L, Yang R, Yuan B, Liu Y, Liu C. 2015. The antiviral and antimicrobial activities of licorice, a widely-used Chinese herb. Acta Pharmaceutica Sinica B. 5(4):310–315.
  • Wolkerstorfer A, Kurz H, Bachhofner N, Szolar OHJ. 2009. Glycyrrhizin inhibits influenza A virus uptake into the cell. Antiviral Res. 83(2):171–178.
  • Yamada H, Daimon T, Matsuda K, Yoshida M, Takuma N, Hara Y. 2007. A randomized controlled study on the effects of gargling with tea catechin extracts on the prevention of influenza infection in healthy adults. Rinsho Yakuri/Jpn J Clin Pharmacol Ther. 38(5):323–330.
  • Yamada H, Takuma N, Daimon T, Hara Y. 2006. Gargling with tea catechin extracts for the prevention of influenza infection in elderly nursing home residents: a prospective clinical study. JAlternComplement Med. 12(7):669–672.
  • Yin Y, Wunderink RG. 2018. MERS, SARS and other coronaviruses as causes of pneumonia. Respirology. 23(2):130–137.