Proliferative activity of various grades and types of breast carcinoma using AgNOR (Argyrophilic Nuclear Organizer Region) expression and its prognostic significance

References

• Abboud P, Lorenzato M, Joly D, Quereux C, Birembaut P, Ploton D. 2008. Prognostic value of a proliferation index including MIB1 and argyrophilic nucleolar organizer regions proteins in node-negative breast cancer. Am J Obstet Gynecol. 199(2):146.e1–146.e7. doi:10.1016/j.ajog.2008.02.025.
   Web of Science ®Google Scholar
• Ades F, Zardavas D, Bozovic-Spasojevic I, Pugliano L, Fumagalli D, de Azambuja E. 2014. Luminal B breast cancer: molecular characterization, clinical management, and future perspectives. J Clin Oncol. 32(25):2794–2803. doi:10.1200/JCO.2013.54.1870.
   PubMed Web of Science ®Google Scholar
• Ahmad SO, Baun J, Tipton B, Tate Y, Switzer RC. 2019. Modification of AgNOR staining to reveal the nucleolus in thick sections specified for stereological and pathological assessments of brain tissue. Heliyon. 5:e03047. doi:10.1016/j.heliyon.2019.e03047.
   Web of Science ®Google Scholar
• Albanese F, Salerni FL, Giordano S, Marconato L. 2006. Extragenital transmissible venereal tumour associated with circulating neoplastic cells in an immunologically compromised dog. Vet Comp Oncol. 4:57–62.
   Web of Science ®Google Scholar
• Beresford MJ, Wilson GD, Makris A. 2006. Measuring proliferation in breast cancer: practicalities and applications. Breast Cancer Res. 8(6):216. doi:10.1186/bcr1618.
   PubMed Web of Science ®Google Scholar
• Biesterfeld S, Reitmaier M. 2001. Re-evaluation of prognostic mitotic figure counting in breast cancer: results of a prospective clinical follow-up study. Anticancer Res. 21(1B):589–594.
   Web of Science ®Google Scholar
• Bonotto M, Gerratana L, Poletto E, Driol P, Giangreco M, Russo S, et al. 2014. Measures of outcome in metastatic breast cancer: insights from a real-world scenario. Oncologist. 19(6):608–615. doi:10.1634/theoncologist.2014-0002.
   PubMed Web of Science ®Google Scholar
• Bourgeois CA, Hernandez-Verdun D, Hubert J, Bouteille M. 1979. Silver staining of NORs in electron microscopy. Exp Cells Res. 123(2):449–452. doi:10.1016/0014-4827(79)-90498-1.
   Web of Science ®Google Scholar
• Canadian Cancer Society. 2009. Canadian cancer statistics at a glance: cancer in children. Can Med Assoc J. 180:422–424. 10.1503/cmaj.081155: Canada.
   Web of Science ®Google Scholar
• Cardoso F, Costa A, Norton L, Senkus E, Aapro M, André F. 2014. ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2). Breast. 23(5):489–502. doi:10.1016/j.breast.2014.08.009.
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and Prevention (CDC). 2013. Cervical cancer screening among women aged 18–30 years – United States, 2000–2010. MMWR Morb Mortal Wkly Rep. 61(51-52):1038–1042.
   PubMed Web of Science ®Google Scholar
• Clegg-Lamptey JNA, Hodasi WM. 2007. A study of breast cancer in Korle Bu teaching hospital: assessing the impact of health education. Ghana Med J. 41(2):72–77.
   PubMedGoogle Scholar
• Coleman MP, Quaresma M, Berrino F, Lutz JM, De Angelis R, Capocaccia R. 2008. Cancer survival in five continents: a worldwide population-based study (CONCORD). Lance Oncol. 9(8):730–756. doi:10.1016/S1470-2045(08)70179-7.
   PubMed Web of Science ®Google Scholar
• Coles C, Condie A, Chetty U, Steel CM, Evans HJ, Prosser J. 1992. P53 mutations in breast cancer. Cancer Res. 52:5291–5298.
   PubMed Web of Science ®Google Scholar
• Crocker J, Macartney JC, Smith JP. 1988. Correlation between DNA flow cytometric and nucleolar organizer region data in non-Hodgkin’s lymphoma. J Pathol. 154(2):151–156. DOI: 10.1002/path.1711540207.
   Web of Science ®Google Scholar
• Darkwah WK, Aidoo G, Ao Y, Danquah KO, Adjei E, Adankwah E, Kadri A. 2018. Assessment of proliferative index in different grades of breast cancers using AGNOR (Argyrophilic Nuclear Organizer Region) expression. Beni-Suef Univ J Basic Appl Sci. 7(4):587–592. doi:10.1016/j.bjbas.2018.06.011.
   Google Scholar
• Das U, Das AK. 2000. Review of canine transmissible venereal sarcoma. Vet Res Commun. 27:545–556.
   Google Scholar
• Dasgupta A, Ghosh RN, Sarkar R, Laha RN, Ghosh TK, Mukherjee C. 1997. Argyrophilic nucleolar organiserregions (AgNORs) in breast lesions. J Indian Med Assoc. 95(9):492–494.
   Google Scholar
• de Azambuja E, Cardoso F, Jr dCG, Colozza M, Mano MS, Durbecq V. 2007. Ki-67 as a prognostic marker in early breast cancer: meta-analysis of published studies involving 12,155 patients. Br J Cancer. 96(10):1504–1513. DOI: 10.1038/sj.bjc.6603756.
   PubMed Web of Science ®Google Scholar
• DeBruin LS, Josephy PD. 2002. Perspective on the chemical etiology of breast cancer. Environ Health Perspect. 110(Suppl. 1):119–128. doi:10.1289/ehp.02110s1119.
   PubMedGoogle Scholar
• Derenzini M, Ploton D. 1991. Interphase nucleolar organizer region in cancer cell. Int Rev EXP Pathol. 32:149–192.
   PubMedGoogle Scholar
• Derenzini M, Thiry M, Gessens G. 1990. Ultrastructural cytochemistry of the mammalian cell nucleolus. J Histochem Cytochem. 38:1237–1256. doi:10.1177/38.9.2201735.
   PubMed Web of Science ®Google Scholar
• Dufresne A, Pivot X, Tournigand C, Facchini T, Alweeg T, Chaigneau L. 2008. Maintenance hormonal treatment improves progression free survival after a first-line chemo-therapy in patients with metastatic breast cancer. Int J Med Sci. 5(2):100–105.
   Google Scholar
• Fallowfield ME, Dodson AR, Cook MG. 1988. Nucleolar organizer regions in melanocytic dysplasia and melanoma. Histopathology. 13(1):95–99. DOI: 10.1111/j.1365-2559.1988.tb02007.x.
   Web of Science ®Google Scholar
• Ferlay J, Shin H-R, Bray F, Forman D, Mathers C, Parkin DM. 2010. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 127(12):2893–2917. doi:10.1002/ijc.25516.
   PubMed Web of Science ®Google Scholar
• Gangul YB, Das U, Das AK. 2013. Canine transmissible venereal tumour- a review. Vet Comp Oncol. 14(1):1–12.
   Google Scholar
• Gerdes J, Lemke H, Baisch H, Wacker HH, Schwab U, Stein H. 1984. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol. 133(4):1710–1715.
   PubMed Web of Science ®Google Scholar
• Goldman MB, Hatch MC. 2000. Breast cancer epidemology, treatment, and prevention. In: Ursin G, Spicer D, editor. Women and health. London: Academic Press; p. 871–883.
   Google Scholar
• Harmelin A, Zuckerman A, Nyska A. 1995. Correlation of AgNOR protein measurements with prognosis in canine transmissible venereal tumour. J Comp Pathol. 112:429–433.
   Web of Science ®Google Scholar
• Hernandez-Verdun D, Hubert J, Bourgeois CA, Bouteille M. 1980. Ultra-structural localization of Ag-NORs stained proteins in nucleolus during the cell cycle and in other nucleolar structures. Chromosoma. 79(3):349–362.
   Web of Science ®Google Scholar
• Kennecke H, Yerushalmi R, Woods R, Cheang MC, Voduc D, Speers CH. 2010. Metastatic behavior of breast cancer subtypes. J Clin Oncol. 28(20):3271–3277. doi:10.1200/JCO.2009.25.9820.
   PubMed Web of Science ®Google Scholar
• Khan SA, Chaudhry NA, Khalid AW, Akhtar GN, Ibne-Rasa SN. 2006. Patterns of argyrophilic nucleolar organiser regions in pleural and peritoneal effusion. J Coll Physicians Surg Pak. 16(6):412–415. 6.2006/JCPSP.412415.
   Google Scholar
• Kinoshita Y, Dohi M, Mizutoni N, et al. 2012. Effects of preoperative radiation and chemotherapy on AgNOR counts in oral squamous cell carcinoma. J Oral Maxillofac Surg. 54:304–307.
   Google Scholar
• Kloke O, Klaassen U, Oberhoff C, Hartwich G, Szanto J, Wolf E. 1999. Maintenance treatment with medroxyprogesterone acetate in patients with advanced breast cancer responding to chemotherapy: results of a randomized trial. Essen Breast Cancer Study Group. Breast Cancer Res Treat. 55(1):51–59.
   PubMed Web of Science ®Google Scholar
• Kobylakov DS, Avdalyan AM, Lazarev AF, Lushnikova EL, Nepomnyashchikh LM. 2014. Argyrophilic nucleolar organizer region in MIB-1 positive cells in non-small cell lung cancer: clinicopathological significance and survival. Cancer Biol Med. 11(4):264–269. doi:10.7497/j.issn.2095-3941.2014.04.005.
   Google Scholar
• Krüger S, Stahlhut M, Müller H. 2000. Cell cycle dependent AgNOR analysis in invasive breast cancer. Anal Quant Cytol Histol. 22(5):358–563.
   Google Scholar
• Kuntz CA, Dernell WS, Powers BE, Devitt C, Straw RC, Withrow SJ. 1997. Prognostic factors for surgical treatment of soft-tissue sarcomas in dogs: 75 cases (1986–1996). J Am Vet Med Assoc. 211(9):1147–1151.
   Web of Science ®Google Scholar
• Lakshmi S, Nair SA, Jayashree R. 1993. Argyrophilic nucleolar organizer region (AgNOR) in inflammatory, premalignant and malignant lesions of the uterine cervix. Cancer Lett. 71:197–201.
   Web of Science ®Google Scholar
• Largillier R, Ferrero JM, Doyen J, Barriere J, Namer M, Mari V. 2008. Prognostic factors in 1038 women with metastatic breast cancer. Ann Oncol. 19(12):2012–2019. doi:10.1093/annonc/mdn424.
   PubMed Web of Science ®Google Scholar
• Lavenir I, Passarella D, Masuda-Suzukake M, Curry A, Holton JL, Ghetti B, Goedert M. 2019. Silver staining (Campbell-Switzer) of neuronal α-synuclein assemblies induced by multiple system atrophy and Parkinson’s disease brain extracts in transgenic mice. Acta Neuropathol Commun. 7(1):148.
   Web of Science ®Google Scholar
• Lee I, Oguma Y. 2006. Physical activity. In: Schottenfeld D, Fraumeni JF, editor. Cancer epidemiology and prevention. New York: Oxford University Press. doi:10.1093/acprof:oso/9780195149616.001.0001
   Google Scholar
• Lehr HA, Hansen DA, Kussick S, Li M, Hwang H, Krummenauer F. 1999. Assessment of proliferative activity in breast cancer: MIB-1 immunohistochemistry. Hum Pathol. 30(11):1314–1320. doi:10.1016/S0046-8177(99)90062-X.
   Web of Science ®Google Scholar
• Lichtenstein P, Holm NV, Verkasalo PK, Iliadou A, Kaprio J, Koskenvuo M. 2000. Environmental and heritable factors in the causation of cancer – analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med. 343(2):78–85. doi:10.1056/NEJM200007133430201.
   PubMed Web of Science ®Google Scholar
• Lobbezoo DJ, van Kampen RJ, Voogd AC, Dercksen MW, van den Berkmortel F, Smilde TJ. 2013. Prognosis of metastatic breast cancer subtypes: the hormone receptor/HER2-positive subtype is associated with the most favorable outcome. Breast Cancer Res Treat. 141(3):507–514. doi:10.1007/s10549-013-2711-y.
   PubMed Web of Science ®Google Scholar
• Meyer JS, Province M. 1988. Proliferative index of breast carcinoma by thymidine labelling: prognostic power independent of stage, estrogen and progesterone receptors. Breast Cancer Res Treat. 12(2):191–204.
   Web of Science ®Google Scholar
• Mohanty G, Padhy K. 2020. Diagnostic and prognostic importance of AgNOR pleomorphism in cervical carcinoma. Indian J Gynecol Oncol. 18:94. doi:10.1007/s40944-020-00441-4(0123).
   Web of Science ®Google Scholar
• Montemurro F, Rondon G, Ueno NT, Munsell M, Gajewski JL, Champlin RE. 2002. Factors affecting progression-free survival in hormone-dependent metastatic breast cancer patients receiving high-dose chemotherapy and hematopoietic progenitor cell transplantation: role of maintenance endocrine therapy. Bone Marrow Transpl. 29(10):861–866. doi:10.1038/sj.bmt.1703555.
   Web of Science ®Google Scholar
• Mourad WA, Erkman-Balis B, Livingston S, Shoukri M, Cox CE, Nicosia SV. 1992. Argyrophilic nucleolar organizer regions in breast carcinoma. Correlation with DNA flow cytometry, histopathology, and lymph node status. Cancer. 69(7):1739–1744. doi:10.1002/1097-0142(19920401)69:7<1739::AID-CNCR2820690715>3.0.CO;2-9.
   Web of Science ®Google Scholar
• Nak D, Nak Y, Cangul IT, Tun B. 2005. A clinico-pathological study on the effect of vincristine on transmissible venereal tumour in dogs. J Vet Med. 52:366–370.
   Google Scholar
• Öfner D, Bier B, Heinrichs S, Berghorn M, Dünser M, Hagemann H-A. 1996. Demonstration of silver-stained nucleolar organizer region associated proteins (AgNORs) after wet autoclave pretreatment in breast carcinoma: correlation to tumor stage and long term survival. Breast Cancer Res Treat. 39(2):165–176.
   Web of Science ®Google Scholar
• Ogura S, Abe S, Sukoh N, Kunikane H, Nkajima I. 1992. Correlation between nucleolar organizer regions visualized by silver staining and the growth rate in lung adenocarcinoma. Cancer. 70(1):63–68. doi:10.1002/1097-0142(19920701)70:1<63::AID-CNCR2820700111>3.0.CO;2-V.
   Web of Science ®Google Scholar
• Petrucelli N, Daly BM, Feldman GL. 2013. BRCA1 and BRCA2 hereditary breast and ovarian cancer. 210-234 In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, editor. Genereviewes®. Seattle: University of Washington.
   Google Scholar
• Pich A, Chiusa L, Margaria E. 1995. Role of argyrophilic nuclear organizer regions in tumour detection and prognosis. Cancer Detect Prev. 19(3):282–291.
   Google Scholar
• Ploton D, Menager M, Jeannesson P, Himber G, Pigeon F, Adnet JJ. 1986. Improvement in the staining and in the visualization of the argyrophilic proteins of the nucleolar organizer region at the optical level. Histochem J. 18(1):5–14.
   PubMedGoogle Scholar
• Ploton D, Visseaux-Coletto B, Canellas JC, Bourzat C, Adnet JJ, Lechki C, Bonnet N. 1992. Semiautomatic quantification of silver-stained nucleolar organizer regions in tissue sections and cellular smears. Anal Quant Cytol Histol. 14(1):14–23.
   Google Scholar
• Reis Filho NP, Torres AAA, Silva MPC. 2020. Transmissible venereal tumor: cell proliferation (Agnor) and response of chemotherapy correlated with cytomorphological classification. ARS VETERINARIA. Jaboticabal. 36(2):140–147. doi:10.15361/2175-0106.2020v36n2p140-147.
   Google Scholar
• Rüschoff J, Neumann K, Contractor H, Plate K, Thomas C. 1990. Assessment of nucleolar organizer regions by automatic image analysis in breast cancer correlation with DNA content, proliferation rate, receptor status and histopathological grading. J Cancer Res Clin Oncol. 116(5):480–485.
   Web of Science ®Google Scholar
• Rzymowska J. 1997. AgNOR counts and their combination with flow cytometric analyses and clinical parameters as a prognostic indicator in breast carcinoma. Tumori. 83(6):938–942. doi:10.1177/030089169708300613.
   Web of Science ®Google Scholar
• Santagata S, Thakkar A, Ergonul A, Wang B, Woo T, Hu R. 2014. Taxonomy of breast cancer based on normal cell phenotype predicts outcome. J Clin Invest. 124(2):859–870. doi:10.1172/JCI70941.
   PubMed Web of Science ®Google Scholar
• Sarli G, Preziosi R, Benazzi C, Castellani G, Marcato PS. 2002. Prognostic value of histologic stage and proliferative activity in canine malignant mammary tumors. J Vet Diagn Invest. 14(1):25–34. doi:10.1177/104063870201400106.
   Web of Science ®Google Scholar
• Sharma M, Manjari M, Kahlon SK. 2011. Proliferative indices, Ki-67 immunostaining and nucleolar organizer region associated protein and their association with various grades of breast carcinomas. J Clin Diagn Res. 5(7):1371–1374.
   Google Scholar
• Shields AF, Mankoff DA, Link JM, Graham MM, Eary JF, Kozawa SM. 1998. Carbon-11-thymidine and FDG to measure therapy response. J Nucl Med. 39(10):1757–1762.
   Web of Science ®Google Scholar
• Shier D, Jackie B, Ricki L. 2012. Hole’s essentials of human anatomy and physiology. New York: McGraw-Hill.
   Google Scholar
• Sinn HP, Lehnert T, Kandetzki C, Waldherr R. 1989. Nucleolar organizer regions in myogenic stromal tumours of the stomach. Virchows Arch A Pathol Anat Histopathol. 415(4):317–321.
   Google Scholar
• Sivridis E, Sims B. 1990. Nucleolar organiser regions: new prognostic variable in breast carcinomas. J Clin Pathol. 43(5):390–392. doi:10.1136/jcp.43.5.390.
   Web of Science ®Google Scholar
• Soerjomataram I, Lortet-Tieulent J, Parkin DM, Ferlay J, Mathers C, Forman D, Bray F. 2012. Global burden of cancer in 2008: a systematic analysis of disability-adjusted life-years in 12 world regions. Lancet. 380(9856):1840–1850. doi:10.1016/s0140-6736(12)60919-2.
   PubMed Web of Science ®Google Scholar
• Srivastava AN, Srivastava S, Bansal C, Misra JS. 2013. Diagnostic importance of AgNOR pleomorphism in cervical carcinogenesis. Ecancer. 7:287. doi:10.3332/ecancer.2013.287.
   Google Scholar
• Sullivan RP, Mortimer G, Muircheartaigh IO. 1993. Cell proliferation in breast tumours: analysis of histological parameters Ki67 and PCNA expression. Ir J Med Sci. 162(9):343–347. doi:10.1007/BF02942162.
   Web of Science ®Google Scholar
• Suresh UR, Chawner L, Buckley H. 1990. Do AgNOR counts reflect cellular ploidy or cellular proliferation? J Pathol. 160:213–215.
   PubMed Web of Science ®Google Scholar
• Trerè D. 2000. AgNOR staining and quantification. Micron. 31(2):127–131. doi:10.1016/S0968-4328(99)00069-4.
   Web of Science ®Google Scholar
• Trerè D, Pession A. 1989. The silver-stained proteins of interphasic nucleolar organizer regions as a parameter of cell duplication rate. Exp Cell Res. 184(1):131–137. doi:10.1016/0014-4827(89)90371-6.
   Web of Science ®Google Scholar
• van Diest PJ, van der Wall E, Baak JP. 2004. Prognostic value of proliferation in invasive breast cancer: a review. J Clin Pathol. 57(7):675–681. doi:10.1136/jcp.2003.010777.
   PubMed Web of Science ®Google Scholar
• Volante M, Cavallo GP, Papotti M. 2004. Prognostic factors of clinical interest in poorly differentiated carcinomas of the thyroid. Endocr Pathol. 15(4):313–317. doi:10.1385/EP:15:4:313.
   Web of Science ®Google Scholar
• Winzer KJ, Bellach J, Hufnagl P. 2013. Long-term analysis to objectify the tumour grading by means of automated microscopic image analysis of the nucleolar organizer regions (AgNORs) in the case of breast carcinoma. Diagn Pathol. 8:56. doi:10.1186/1746-1596-8-56.
   Web of Science ®Google Scholar
• Wojnar A, Kobierzycki C, Krolica A, Pula B, Podharska OM, Dziegeil P. 2010. Correlation of the Ki-67 and the MCM-2 proliferative markers with the grade of the histological malignancy (G) in ductal breast cancers. Folia Histochem Cytobiol. 48(3):442–446. doi:10.2478/v10042-010-0069-0.
   Web of Science ®Google Scholar
• Yang P, Hang GS, Zhu XS. 1990. Role of nucleolar organizer regions in differentiating malignant from benign tumours of the colon. J Clin Pathol. 43:235–238.
   Web of Science ®Google Scholar
• Zografos GC, Panou M, Panou N. 2004. Common risk factors of breast and ovarian cancer: recent review. Int J Gynecol Cancer. 14(5):721–740. doi:10.1111/j.1048-891X.2004.14503.x.
   Web of Science ®Google Scholar