127
Views
5
CrossRef citations to date
0
Altmetric
Articles

miR-30d-5p represses the proliferation, migration, and invasion of lung squamous cell carcinoma via targeting DBF4

, & ORCID Icon

References

  • Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394–424. doi:10.3322/caac.21492.
  • Ghouri YA, Mian I, Blechacz B. Cancer review: cholangiocarcinoma. J Carcinog. 2015;14:1. doi:10.4103/1477-3163.151940.
  • Chen Z, Fillmore CM, Hammerman PS, Kim CF, Wong KK. Non-small-cell lung cancers: a heterogeneous set of diseases. Nat Rev Cancer. 2014;14:535–546. doi:10.1038/nrc3775.
  • Goodwin J, Neugent ML, Lee SY, et al. The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition. Nat Commun. 2017;8:15503. doi:10.1038/ncomms15503.
  • Kinoshita A, Onoda H, Fushiya N, et al. Staging systems for hepatocellular carcinoma: current status and future perspectives. World J Hepatol. 2015;7:406–424. doi:10.4254/wjh.v7.i3.406.
  • Land SR, Liu Q, Wickerham DL, Costantino JP, Ganz PA. Cigarette smoking, physical activity, and alcohol consumption as predictors of cancer incidence among women at high risk of breast cancer in the NSABP P-1 trial. Cancer Epidemiol Biomarkers Prev. 2014;23(5):823–832. doi:10.1158/1055-9965.EPI-13-1105-T.
  • Tejeda-Maldonado J, García-Juárez I, Aguirre-Valadez J, et al. Diagnosis and treatment of hepatocellular carcinoma: an update. World J Hepatol. 2015;7:362–376. doi:10.4254/wjh.v7.i3.362.
  • Drilon A, Rekhtman N, Ladanyi M, Paik P. Squamous-cell carcinomas of the lung: emerging biology, controversies, and the promise of targeted therapy. Lancet Oncol. 2012;13:e418–e426. doi:10.1016/S1470-2045(12)70291-7.
  • Gao M, Kong W, Huang Z, Xie Z. Identification of key genes related to lung squamous cell carcinoma using bioinformatics analysis. Int J Mol Sci. 2020;21(8):2994. doi:10.3390/ijms21082994.
  • Bousset K, Diffley JF. The Cdc7 protein kinase is required for origin firing during S phase. Genes Dev. 1998;12:480–490. doi:10.1101/gad.12.4.480.
  • Ogi H, Wang CZ, Nakai W, Kawasaki Y, Masumoto H. The role of the Saccharomyces cerevisiae Cdc7-Dbf4 complex in the replication checkpoint. Gene. 2008;414:32–40. doi:10.1016/j.gene.2008.02.010.
  • Katoh M. Function and cancer genomics of FAT family genes (review). Int J Oncol. 2012;41:1913–1918. doi:10.3892/ijo.2012.1669.
  • Marston AL. Meiosis: DDK is not just for replication. Curr Biol. 2009;19:R74–R76. doi:10.1016/j.cub.2008.12.003.
  • Kwaepila N, Burns G, Leong AS. Immunohistological localisation of human FAT1 (hFAT) protein in 326 breast cancers. Does this adhesion molecule have a role in pathogenesis? Pathology. 2006;38:125–131. doi:10.1080/00313020600559975.
  • Pessoa-Brandao L, Sclafani RA. CDC7/DBF4 functions in the translesion synthesis branch of the RAD6 epistasis group in Saccharomyces cerevisiae. Genetics. 2004;167:1597–1610. doi:10.1534/genetics.103.021675.
  • Takayama Y, Mamnun YM, Trickey M, et al. Hsk1- and SCF(Pof3)-dependent proteolysis of S. pombe Ams2 ensures histone homeostasis and centromere function. Dev Cell. 2010;18:385–396. doi:10.1016/j.devcel.2009.12.024.
  • Miller CT, Gabrielse C, Chen YC, Weinreich M. Cdc7p-Dbf4p regulates mitotic exit by inhibiting Polo kinase. PLoS Genet. 2009;5:e1000498. doi:10.1371/journal.pgen.1000498.
  • Johnston LH, Thomas AP. A further two mutants defective in initiation of the S phase in the yeast Saccharomyces cerevisiae. Mol Gen Genet. 1982;186:445–448. doi:10.1007/BF00729467.
  • Matthews LA, Guarne A. Dbf4: the whole is greater than the sum of its parts. Cell Cycle. 2013;12:1180–1188. doi:10.4161/cc.24416.
  • Barkley LR, Santocanale C. MicroRNA-29a regulates the benzo[a]pyrene dihydrodiol epoxide-induced DNA damage response through Cdc7 kinase in lung cancer cells. Oncogenesis. 2013;2:e57. doi:10.1038/oncsis.2013.20.
  • He Y, Lin J, Kong D, et al. Current state of circulating microRNAs as cancer biomarkers. Clin Chem. 2015;61:1138–1155. doi:10.1373/clinchem.2015.241190.
  • Lu TX, Rothenberg ME. MicroRNA. J Allergy Clin Immunol. 2018;141:1202–1207. doi:10.1016/j.jaci.2017.08.034.
  • Kumar B, Khaleghzadegan S, Mears B, et al. Identification of miR-30b-3p and miR-30d-5p as direct regulators of androgen receptor signaling in prostate cancer by complementary functional microRNA library screening. Oncotarget. 2016;7:72593–72607. doi:10.18632/oncotarget.12241.
  • Hung CH, Chiu YC, Chen CH, Hu TH. MicroRNAs in hepatocellular carcinoma: carcinogenesis, progression, and therapeutic target. Biomed Res Int. 2014; 2014:1–11. (2014). doi:10.1155/2014/486407.
  • Tarasov VA, Matishov DG, Shin EF, et al. Coordinated aberranit expression of miRNAs in colon cancer. Genetika. 2014;50:1232–1244.
  • Larsen AC. Conjunctival malignant melanoma in Denmark. Epidemiology, treatment and prognosis with special emphasis on tumorigenesis and genetic profile. Acta Ophthalmol. 2016;94:842. doi:10.1111/aos.13207.
  • Xu J, Wu C, Che X, et al. Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis. Mol Carcinog. 2011;50:136–142. doi:10.1002/mc.20712.
  • Chen D, Guo W, Qiu Z, et al. MicroRNA-30d-5p inhibits tumour cell proliferation and motility by directly targeting CCNE2 in non-small cell lung cancer. Cancer Lett. 2015;362:208–217. doi:10.1016/j.canlet.2015.03.041.
  • Song Y, Song C, Yang S. Tumor-suppressive function of miR-30d-5p in prostate cancer cell proliferation and migration by targeting NT5E. Cancer Biother Radiopharm. 2018;33:203–211. doi:10.1089/cbr.2018.2457.
  • Sasi NK, Bhutkar A, Lanning NJ, MacKeigan JP, Weinreich M. DDK promotes tumor chemoresistance and survival via multiple pathways. Neoplasia. 2017;19:439–450. doi:10.1016/j.neo.2017.03.001.
  • Pavel AB, Campbell JD, Liu G, et al. Alterations in bronchial airway miRNA expression for lung cancer detection. Cancer Prev Res. 2017;10(11):651–659. doi:10.1158/1940-6207.CAPR-17-0098.
  • Gao L, He R-Q, Wu H-Y, et al. Expression signature and role of miR-30d-5p in non-small cell lung cancer: a comprehensive study based on in silico analysis of public databases and in vitro experiments. Cell Physiol Biochem. 2018;50(5):1964–1987. doi:10.1159/000494875.
  • Han HS, Kim MJ, Han JH, et al. Bile-derived circulating extracellular miR-30d-5p and miR-92a-3p as potential biomarkers for cholangiocarcinoma. Hepatobiliary Pancreat Dis Int. 2020;19:41–50. doi:10.1016/j.hbpd.2019.10.009.
  • Bjornetro T, Redalen KR, Meltzer S, et al. An experimental strategy unveiling exosomal microRNAs 486-5p, 181a-5p and 30d-5p from hypoxic tumour cells as circulating indicators of high-risk rectal cancer. J Extracell Vesicles. 2019;8:1567219. doi:10.1080/20013078.2019.1567219.
  • Zhu Y, Liu J, Fan L, et al. Serum expression and significance of MicroRNA-30d-5p in esophageal squamous cell carcinoma. Int J Clin Exp Pathol. 2017;10:8677–8685.
  • Jackson AL, Pahl PM, Harrison K, Rosamond J, Sclafani RA. Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 protein. Mol Cell Biol. 1993;13:2899–2908. doi:10.1128/mcb.13.5.2899.
  • Sasi NK, Tiwari K, Soon FF, et al. The potent Cdc7-Dbf4 (DDK) kinase inhibitor XL413 has limited activity in many cancer cell lines and discovery of potential new DDK inhibitor scaffolds. PLoS One. 2014;9:e113300. doi:10.1371/journal.pone.0113300.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.