1,549
Views
1
CrossRef citations to date
0
Altmetric
Emerging Topics in Nutrition

Role of Acacia catechu and Scutellaria baicalensis in Enhancing Immune Function Following Influenza Vaccination of Healthy Adults: A Randomized, Triple-Blind, Placebo-Controlled Clinical Trial

, , &
Pages 678-690 | Received 15 Jul 2022, Accepted 04 Nov 2022, Published online: 22 Nov 2022

References

  • Health Canada. Flu (influenza): for health professionals; [accessed 2021 Aug 18]. https://www.canada.ca/en/public-health/services/diseases/flu-influenza/health-professionals.html#a8.
  • CDC. Influenza (Flu); [accessed 2021 Aug 18]. https://www.cdc.gov/flu/season/faq-flu-season-2020-2021.htm.
  • Dawood FS, Chung JR, Kim SS, Zimmerman RK, Nowalk MP, Jackson ML, Jackson LA, Monto AS, Martin ET, Belongia EA, et al. Interim estimates of 2019–20 seasonal influenza vaccine effectiveness—United States, February 2020. MMWR Morb Mortal Wkly Rep. 2020;69(7):177–82. doi:10.15585/mmwr.mm6907a1
  • Flannery B, Kondor RJG, Chung JR, Gaglani M, Reis M, Zimmerman RK, Nowalk MP, Jackson ML, Jackson LA, Monto AS, et al. Spread of antigenically drifted influenza A (H3N2) viruses and vaccine effectiveness in the United States during the 2018–2019 season. J Infect Dis. 2020;221(1):8–15. doi:10.1093/infdis/jiz543
  • Calder PC, Carr AC, Gombart AF, Eggersdorfer M. Optimal nutritional status for a well-functioning immune system is an important factor to protect against viral infections. Nutrients. 2020;12(4):1181. doi:10.3390/nu12041181
  • Pae M, Meydani SN, Wu D. The role of nutrition in enhancing immunity in aging. Aging Dis. 2012;3(1):91–129.
  • Yeh T-L, Shih P-C, Liu S-J, Lin C-H, Liu J-M, Lei W-T, Lin C-Y. The influence of prebiotic or probiotic supplementation on antibody titers after influenza vaccination: a systematic review and meta-analysis of randomized controlled trials. Drug Des Devel Ther. 2018;12:217–30. doi:10.2147/DDDT.S155110
  • Rizzardini G, Eskesen D, Calder PC, Capetti A, Jespersen L, Clerici M. Evaluation of the immune benefits of two probiotic strains Bifidobacterium animalis ssp. lactis, BB-12® and Lactobacillus paracasei ssp. paracasei, L. casei 431® in an influenza vaccination model: a randomised, double-blind, placebo-controlled study. Br J Nutr. 2012;107(6):876–84. doi:10.1017/s000711451100420x
  • Xiao L, Engen PA, Leusink-Muis T, van Ark I, Stahl B, Overbeek SA, Garssen J, Naqib A, Green SJ, Keshavarzian A, et al. The combination of 2’-fucosyllactose with short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides that enhance influenza vaccine responses is associated with mucosal immune regulation in mice. J Nutr. 2019;149(5):856–69. doi:10.1093/jn/nxz006
  • Fernández-Ferreiro A, Formigo-Couceiro FJ, Veiga-Gutierrez R, Maldonado-Lobón JA, Hermida-Cao AM, Rodriguez C, Bañuelos O, Olivares M, Blanco-Rojo R. Effects of Loigolactobacillus coryniformis K8 CECT 5711 on the immune response of elderly subjects to COVID-19 vaccination: a randomized controlled trial. Nutrients. 2022;14(1):228. doi:10.3390/nu14010228
  • Tseng-Crank J, Sung S, Jia Q, Zhao Y, Burnett B, Park DR, Woo SS. A medicinal plant extract of Scutellaria baicalensis and Acacia catechu reduced LPS-stimulated gene expression in immune cells: a comprehensive genomic study using QPCR, ELISA, and microarray. J Diet Suppl. 2010;7(3):253–72. doi:10.3109/19390211.2010.493169
  • Sunil MA, Sunitha VS, Radhakrishnan EK, Jyothis M. Immunomodulatory activities of Acacia catechu, a traditional thirst quencher of South India. J Ayurveda Integr Med. 2019;10(3):185–91. doi:10.1016/j.jaim.2017.10.010
  • Olivares M, Diaz-Ropero MP, Sierra S, Lara-Villoslada F, Fonolla J, Navas M, Rodriguez JM, Xaus J. Oral intake of Lactobacillus fermentum CECT5716 enhances the effects of influenza vaccination. Nutrition. 2007;23(3):254–60. doi:10.1016/j.nut.2007.01.004
  • Wiggins KB, Smith MA, Schultz-Cherry S. The nature of immune responses to influenza vaccination in high-risk populations. Viruses. 2021;13(6):1109. doi:10.3390/v13061109
  • Rosendahl Huber SK, Hendriks M, Jacobi RHJ, van de Kassteele J, Mandersloot-Oskam JC, van Boxtel RAJ, Wensing AMJ, Rots NY, Luytjes W, van Beek J. Immunogenicity of influenza vaccines: evidence for differential effect of secondary vaccination on humoral and cellular immunity. Front Immunol. 2019;9. doi:10.3389/fimmu.2018.03103
  • Moher D, Hopewell S, Schulz KF, Montori V, Gotzsche PC, Devereaux PJ, Elbourne D, Egger M, Altman DG, Consort. CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. Int J Surg. 2012;10(1):28–55. doi:10.1016/j.ijsu.2011.10.001.
  • Jia Q. Formulation of a mixture of free-B-ring flavonoids and flavans as a therapeutic agent. Patent number US7514469B2. USA, 2009.
  • Yimam M, Zhao Y, Ma W, Jia Q, Do S-G, Shin J-H. 90-day oral toxicity study of UP446, a combination of defined extracts of Scutellaria baicalensis and Acacia catechu, in rats. Food Chem Toxicol. 2010;48(5):1202–9. doi:10.1016/j.fct.2010.02.011
  • Yimam M, Lee YC, Jia Q. 26-week repeated oral dose toxicity study of UP446, a combination of defined extracts of Scutellaria baicalensis and Acacia catechu, in beagle dogs. Regul Toxicol Pharmacol. 2016;78:66–77. doi:10.1016/j.yrtph.2016.04.007
  • Barrett B, Brown RL, Mundt MP, Thomas GR, Barlow SK, Highstrom AD, Bahrainian M. Validation of a short form Wisconsin Upper Respiratory Symptom Survey (WURSS-21). Health Qual Life Outcomes. 2009;7:76. doi:10.1186/1477-7525-7-76
  • Murdoch DR, Slow S, Chambers ST, Jennings LC, Stewart AW, Priest PC, Florkowski CM, Livesey JH, Camargo CA, Scragg R. Effect of vitamin D3 supplementation on upper respiratory tract infections in healthy adults: the VIDARIS randomized controlled trial. JAMA. 2012;308(13):1333–9. doi:10.1001/jama.2012.12505
  • Nantz MP, Rowe CA, Nieves C, Jr, Percival SS. Immunity and antioxidant capacity in humans is enhanced by consumption of a dried, encapsulated fruit and vegetable juice concentrate. J Nutr. 2006;136(10):2606–10. doi:10.1093/jn/136.10.2606
  • de Vrese M, Winkler P, Rautenberg P, Harder T, Noah C, Laue C, Ott S, Hampe J, Schreiber S, Heller K, et al. Probiotic bacteria reduced duration and severity but not the incidence of common cold episodes in a double blind, randomized, controlled trial. Vaccine. 2006;24(44-46):6670–4. doi:10.1016/j.vaccine.2006.05.048
  • R Core Team. R: a language and environment for statistical computing. Vienna (Austria): R Foundation for Statistical Computing; 2019.
  • Moldoveanu Z, Clements ML, Prince SJ, Murphy BR, Mestecky J. Human immune responses to influenza virus vaccines administered by systemic or mucosal routes. Vaccine. 1995;13(11):1006–12. doi:10.1016/0264-410x(95)00016-t
  • Abreu RB, Clutter EF, Attari S, Sautto GA, Ross TM. IgA responses following recurrent influenza virus vaccination. Front Immunol. 2020;11:902. doi:10.3389/fimmu.2020.00902
  • Clements M, Betts R, Tierney E, Murphy B. Serum and nasal wash antibodies associated with resistance to experimental challenge with influenza A wild-type virus. J Clin Microbiol. 1986;24(1):157–60. doi:10.1128/jcm.24.1.157-160.1986
  • Belshe RB, Gruber WC, Mendelman PM, Mehta HB, Mahmood K, Reisinger K, Treanor J, Zangwill K, Hayden FG, Bernstein DI, et al. Correlates of immune protection induced by live, attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine. J Infect Dis. 2000;181(3):1133–7. doi:10.1086/315323
  • Ambrose CS, Wu X, Jones T, Mallory RM. The role of nasal IgA in children vaccinated with live attenuated influenza vaccine. Vaccine. 2012;30(48):6794–801. doi:10.1016/j.vaccine.2012.09.018
  • Schroeder HW, Jr, Cavacini L. Structure and function of immunoglobulins. J Allergy Clin Immunol. 2010;125(2 Suppl 2):S41–S52. doi:10.1016/j.jaci.2009.09.046
  • Li Z-N, Lin S-C, Carney PJ, Li J, Liu F, Lu X, Liu M, Stevens J, Levine M, Katz JM, et al. IgM, IgG, and IgA antibody responses to influenza A(H1N1)pdm09 hemagglutinin in infected persons during the first wave of the 2009 pandemic in the United States. Clin Vaccine Immunol. 2014;21(8):1054–60. doi: 10.1128/CVI.00129-14.
  • MacDonald TT, Bell I. Probiotics and the immune response to vaccines. Proc Nutr Soc. 2010;69(3):442–6. doi:10.1017/s0029665110001758
  • Chen K-K, Minakuchi M, Wuputra K, Ku C-C, Pan J-B, Kuo K-K, Lin Y-C, Saito S, Lin C-S, Yokoyama KK. Redox control in the pathophysiology of influenza virus infection. BMC Microbiol. 2020;20(1):214. doi:10.1186/s12866-020-01890-9
  • Phillips M, Cataneo RN, Chaturvedi A, Danaher PJ, Devadiga A, Legendre DA, Nail KL, Schmitt P, Wai J. Effect of influenza vaccination on oxidative stress products in breath. J Breath Res. 2010;4(2):026001. doi:10.1088/1752-7155/4/2/026001
  • Lubos E, Loscalzo J, Handy DE. Glutathione peroxidase-1 in health and disease: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal. 2011;15(7):1957–97. doi:10.1089/ars.2010.3586
  • Handy DE, Loscalzo J. The role of glutathione peroxidase-1 in health and disease. Free Radic Biol Med. 2022;188:146–61. doi:10.1016/j.freeradbiomed.2022.06.004
  • Semba RD, Nicklett EJ, Ferrucci L. Does accumulation of advanced glycation end products contribute to the aging phenotype? J Gerontol A Biol Sci Med Sci. 2010;65(9):963–75. doi:10.1093/gerona/glq074
  • Asirvatham JR, Moses V, Bjornson L. Errors in potassium measurement: a laboratory perspective for the clinician. N Am J Med Sci. 2013;5(4):255–9. doi:10.4103/1947-2714.110426
  • Suzuki K, Nakajima A. New aspects of IgA synthesis in the gut. Int Immunol. 2014;26(9):489–94. doi:10.1093/intimm/dxu059
  • Suzuki K, Kawamoto S, Maruya M, Fagarasan S. GALT: organization and dynamics leading to IgA synthesis. Adv Immunol. 2010;107:153–85. doi:10.1016/b978-0-12-381300-8.00006-x
  • Thomas M, Bomar PA. Upper respiratory tract infection. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022.