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Original Articles

The Metabolism of Fructooligosaccharides and Fructooligosaccharide-Related Compounds in Plants

Pages 16-50 | Published online: 01 Sep 2010

References

  • Roberfroid , M.B. 1995 . A functional food: chicory fructooligosaccharides, a colonic food with prebiotic activity . World Ingred. , Mar-April : 42 – 44 .
  • Roberfroid , M.B. 1996 . Functional effects of food components and the gastrointestinal system: chicory fructooligosaccharides . Nutr. Rev. , 54 : S38 – 42 .
  • Tannock , G.W. 1999 . Probiotics: A Critical Reviews , 161 UK : Horizon Specific Science .
  • Duggan , C. , Gannon , J and Walker , W.A . 2002 . Protective nutrients and functional foods for the gastrointestinal tract . Am. J. Clin. Nutr. , 75 ( 5 ) : 789 – 808 .
  • Gibson , G.R. and Roberfroid , M.B. 1995 . Dietary modulation of the human colonic microflora: introducing the concept of prebiotics . J. Nutr. , 125 : 1401 – 1412 .
  • Tomasik , P.J. and Tomasik , P. 2003 . Probiotics and prebiotics . Cereal Chem. , 80 ( 2 ) : 113 – 117 .
  • Kolida , S. , Tuohy , K. and Gibson , G.R. 2002 . Prebiotic effects of inulin and oligofructose . Br. J. Nutr. , 87 ( 2 ) : S193 – S197 .
  • Hidaka , H. , Hirayama , M. and Yamada , K. 1991 . Fructooligosaccharides: enzymatic preparation and biofunctions . J. Carbohydr. Chem. , 10 ( 4 ) : 509 – 522 .
  • Roberfroid , M.B. , Van Loo , J. and Gibson , GR. 1998 . The bifidogenic nature of the chicory inulin and its hydrolysis products . J. Nutr. , 128 ( 1 ) : 11 – 19 .
  • Alles , M.S. , Hartemink , R. , Meyboom , S. , Harryvan , J.K. , Van Laere , K.M.J. , Nanengast , F.M. and Hautvast , J.G.A.J. 1999 . Effect of trans-galactooligosaccharides on composition of the human intestinal microflora and on putative risk markers for colon cancer . Am. J. Clin. Nutr. , 69 ( 5 ) : 980 – 991 .
  • Yoon , M.Y. and Hwang , H.J. 2008 . Reduction of soybean oligosaccharides and properties of alpha-D-galactosidase from Lactobacillus curvatus R08 and Leuconostoc mesenteriodes JK 55 . Food Microbiol. , 25 ( 6 ) : 815 – 823 .
  • Courtin , C.M. , Swennen , K , Broekaert , W.F. , Swennen , Q. , Buyse , J. , Decuypere , E. , Michiels , C.W. , Ketelaere , B.D. and Delcour , J.A. 2008 . Effects of dietary inclusion of xylooligosaccharides, arabinoxylooligosaccharides and soluble arabinoxylan on the microbiol composition of caecal contents of chickens . J. Sci. Food Agric. , 88 ( 14 ) : 2517 – 2522 .
  • Van Loo , J. , Cummings , J. , Delzenne , N. , Englyst , H. , Franck , A. , Hopkins , M. , Kok , N. , MacFarlane , G. , Newton , D. , Quigley , M. , Roberfroid , M. , Van Vliet , T. and Van den Heuvel , E. 1999 . Functional food properties of non-digestible oligosaccharides: A consensus report from the ENDO Project (DGXII AIRII-CT94-1095) . Br. J. Nutr. , 81 ( 2 ) : 121 – 132 .
  • Wollowski , I. , Rechkemmer , G. and Pool-Zobel , B.L. 2001 . Protective role of probiotics and prebiotics in colon cancer . Am. J. Clin. Nutr. , 73 : S451 – S455 .
  • Roberfroid , M.B. and Delzenne , N.M. 1998 . Dietary fructans . Annu. Rev. Nutr. , 18 : 117 – 143 .
  • Gibson , G.R. and Roberfroid , M.B. 2008 . Handbook of Prebiotics , 504 Boca Raton : CRC Press Taylor&Francis Group .
  • Cassidy , M.M. , Bingham , S.A. and Cummings , J.H. 1994 . Starch intake and colorectal cancer risk: An international comparison . Br. J. Cancer. , 69 : 937 – 942 .
  • Flickinger , E.A. and Fahey Jr , G.C. 2002 . Pet food and feed applications of inulin and oligofructose . Br. J. Nutr. , 87 ( suppl. 2 ) : S297 – S300 .
  • Bach Knudsen , K.E. and Hessov , I. 1995 . Recovery of inulin from Jerusalem artichoke (Helianthus tuberosus L.) in the small intestine of man . Br. J. Nutr. , 74 : 101 – 103 .
  • Molis , Ch , Flourié , B. , Ouarne , F. , Gailling , M.F. , Lartigue , S. , Guibert , A. , Bornet , F. and Galmiche , J.P. 1996 . Digestion, excretion, and energy value of fructooligosaccharides in healthy humans . J. Am. Clin. Nutr. , 64 : 324 – 328 .
  • Nilsson , U. , Öste , R. , Jägerstad , M. and Birkhed , D. 1998 . Cereal fructans: in vitro and in vivo studies on availability in rats and humans . J. Nutr. , 118 : 1325 – 1330 .
  • Delzenne , N. and Roberfroid , M. 1994 . Physiological effects of non-digestible oligosaccharides . Lebensmittel Wissenchaft und Technologie. , 27 : 1 – 6 .
  • Roberfroid , M.B. and Slavin , J. 2000 . Non-digestible oligosaccharides . Crit. Rev. Food Sci. Nutr. , 40 : 461 – 480 .
  • Gibson , P.R. , Newnham , E. , Barrett , J.S. , Shepherd , S.J. and Muir , J.G. 2007 . Review article: Fructose malabsorption and the bigger picture . Aliment. Pharmacol. Ther. , 25 : 349 – 363 .
  • Ellegärd , L. , Andersson , H. and Bosaeus , I. 1997 . Inulin and oligofructose do not influence the absorption of cholesterol, or the excretion of cholesterol, Ca, Mg, Zn, Fe, or bile acids but increase in ileostomy subjects . Eur. J. Clin. Nutr. , 51 : 1 – 5 .
  • Campell , J.M. , Fahey , G.C.J and Wolf , B.W. 1997 . Selected indigestible oligosaccharides affect large bowel mass, cecal and faecal SCFAs, pH and microflora in rats . J. Nutr. , 127 : 130 – 136 .
  • Kleessen , B. , Sykura , B. , Zunft , H-J. and Blaut , M. 1997 . Effects of inulin and lactose on fecal microflora, microbial activity, and bowel habit in elderly constipated persons . Am. J. Clin. Nutr. , 65 : 1397 – 1402 .
  • Roberfroid , M.R. 2002 . Functional foods: Concepts and application to inulin and oligofructose . Br. J. Nutr. , 87 ( suppl. 2 ) : S139 – S143 .
  • Tungland , B.C. and Meyer , D. 2002 . Non-digestible oligo- and poly-saccharides (dietary fiber): Their physiology and role in human health and food . Compr. Rev. Food Sci. F. , 3 : 90 – 109 .
  • Itsaranuwat , P. , Khawla , S. , Al-Haddad , H. and Robinson , R.K. 2003 . The potential therapeutic benefits of consuming ‘health-promoting’ fermented dairy products: a brief update. Int . J. Dairy Technol. , 56 ( 4 ) : 203 – 210 .
  • Gibson , G.R. 2004 . From probiotics to prebiotics and a helthy digestive system . J. Food Sci. , 69 ( 5 ) : M141 – M143 .
  • Perrin , S. , Fougnes , C. , Gril , J.P. , Jacobs , H. and Schneider , F. 2002 . Fermentation of chicory fructooligosaccharides in mixtures of different degree of polymerization by three strains of Bifidobacteria. Can . J. Microbiol. , 48 : 759 – 763 .
  • Burr , G. and Gatlin , D. 2005 . Microbial ecology of gastrointestinal tract of fish and the potential application of prebiotics and probiotics in finfish aquaculture . J. World Aquacult. Soc. , 36 ( 4 ) : 425 – 436 .
  • Boehm , G. , Fanaro , S. , Jelinek , J. , Stahl , B. and Marini , A. 2003 . Prebiotic concept for infant nutrition . Acta Pediatr. , 441 ( Suppl. ) : 64 – 67 .
  • Moro , G.E. , Stahl , B. , Fanaro , S. , Jelinek , J. , Boehm , G. and Copa , G.V. 2005 . Dietary prebiotic oligosaccharides are detectable in the faeces of formula-fed infants . Acta Pediatr. , 94 ( suppl. 449 ) : 27 – 30 .
  • Kapiki , A. , Costalos , C. , Oikonomidou , C. , Triantafyllidou , A. , Loukatou , E. and Pertrohilou , V. 2007 . The effect of fructooligosaccharide supplemented formula on gut flora of preterm infants . Early Hum. Dev. , 83 : 335 – 339 .
  • Ohta , A. , Ohtsuki , M. , Baba , S. , Adachi , T. , Sakata , T. and Sakaguchi , E. 1995 . Calcium and magnesium absorption from the colon and rectum are increased in rats fed fructooligosaccharides . J. Nutr. , 125 : 2417 – 2424 .
  • Ohta , A. , Asakabe , N. , Yamada , K. , Saito , Y. and Hidaka , H. 1993 . Effects of fructooligosaccharides and other saccharides on Ca, Mg, and P absorption in rats . J. Jap. Soc. Nutr. Food Sci. , 46 : 123 – 129 .
  • Baba , S. , Ohta , A. , Ohtsuki , M. , Takizawa , T. , Adachi , T. and Hara , H. 1996 . Fructooligosaccharides stimulate the absorption of magnesium from hindgut in rats . Nutr. Res. , 16 : 657 – 666 .
  • Scholz-Ahrens , K. , Van Loo , J. and Schrezenmeir , J. 1998 . The increase in bone mineralization in the ovariectomized rat by oligofructose also depends on Ca supplementation . Zeitschrift für Ernährungswissenschaft. , 37 : 123 – 124 .
  • Van den Heuvel , E.H. , Muys , T. , Dokum , W. , Van and Schaafsma , G. 1999 . Oligofructose stimulates calcium absorption in adolescents . Am. J. Clin. Nutr. , 69 : 544 – 548 .
  • Tahiri , M. , Tressol , J.C. , Arnaud , J. , Bornet , F. , Bouteloup-Demange , C. , Feillet-Coudray , C. , Ducros , V. , Pépin , D. , Brouns , F. , Roussel , A.M. , Rayssguier , Y. and Coudray , C. 2001 . Five-week intake of short-chain fructooligosaccharides increases intestinal absorption and status of Mg in post menapausal women . J. Bone Miner. Res. , 16 ( 11 ) : 1 – 9 .
  • Beynen , A.C. , Bass , J.C. , Hoekemeijer , P.E. , Kappert , H.J. , Bakker , M.H. , Kopman , J.P. and Lemmens , A.G. 2002 . Faecal bacterial profile, nitrogen excretion and mineral absorption in healthy dogs fed supplemental oligofructose . J. Anim. Physiol. A. Anim. Nutr. , 86 : 298 – 305 .
  • Ohta , A. , Ohtsuki , M. , Baba , S. , Hirayama , M. and Adachi , T. 1998 . Comparison of the nutritional effects of fructooligosaccharides of different chain length in rats . Nutr. Research. , 18 ( 1 ) : 109 – 120 .
  • Kok , N. , Roberfroid , M. and Delzenne , N. 1996 . Dietary oligofructose modifies the impact of fructose on hepatic triacylglycerol metabolism . Metabolism. , 45 : 1547 – 1550 .
  • Kok , N. , Roberfroid , M. , Robert , A. and Delzenne , N. 1996 . Involvement of lipogenesis in the lower VLDL secretion induced by oligofructose in rats . Br. J. Nutr. , 76 : 881 – 890 .
  • Kok , N.N. , Taper , H.S. and Delzenne , N.M. 1998 . Oligofructose modulates lipid metabolism alterations induced by a fat-rich diet in rats . J. Appl. Toxicol. , 18 : 47 – 53 .
  • Van Vliet , T. A double blind placebo-controlled, paralel trial on the effect of oligofructose intake on serum lipids in male volunteers Report TNOV 97.874. Zeist:TNO, 1997
  • Causey , J.L. , Feirtag , J.M. , Gallaher , D.D. , Tungland , B.C. and Slavin , J.L . 2000 . Effects of dietary inulin on serum lipid, blood glucose and the gastrointestinal enviroment in hypercholesterolemic men . Nutr. Res. , 20 ( 2 ) : 191 – 201 .
  • Juśkiewicz , J. , Glazka , I. , Krol , B. and Zdwiczyk , Z. 2006 . Effect of chicory production with different inulin content on rat caceum physiology . J. Anim. Physiol. An. N. , 90 : 200 – 207 .
  • Jeusette , I , Grauwels , M , Cuvelier , C. , Tonglet , C. , Istasse , L. and Diez , M. 2004 . Hypercholesterolemia in a family of rough collie dogs . J. Small Anim. Pract. , 45 : 319 – 324 .
  • Liong , M.T. and Shah , N.P. 2004 . Optimization of cholesterol removal, growth and fermentation patterns of Lactobacillus acidophilus ATCC 4962 in the presence of mannitol, fructo-oligosaccharides and inulin: a responce surface methodology approach . J. Appl. Microbiol. , 98 : 1115 – 1125 .
  • Reddy , D.S. , Hamid , R. and Rao , C.V. 1997 . Effect of dietary oligofructose and inulin on preneoplastic aberrant crypt foci inhibition . Carcinogenesis. , 18 : 1371 – 1374 .
  • Taper , H. , Delzenne , N. and Roberfroid , M.B. 1997 . Growth inhibition of transplantable mouse tumors by non-digestible carbohydrates . Int. J. Cancer. , 71 : 1109 – 1112 .
  • Taper , H.S. , Lemort , C. and Roberfroid , M.B. 1998 . Inhibitory effect of dietary inulin and oligofructose on the growth of transplantable mouse tumor . Anticancer Res. , 18 : 4123 – 4126 .
  • Pierre , F. , Perrin , P. , Champ , M. , Bornet , F. , Melfah , K. and Menanteau , J. 1997 . Short-chain fructo-oligosaccharides reduce the occurence of colon tumors and develop gut-associated lymphoid tissue in min mice . Cancer Res. , 57 : 225 – 228 .
  • Gallaher , D.D. , Stallings , W.H. , Blessing , L. , Butsa , F.F. and Brady , L.J. 1996 . Probiotics, cecal microflora, and aberrant crypts in the rat colon . J. Nutr. , 126 : 1362 – 1371 .
  • Rowland , I.R. , Rumney , C.J. , Coutts , J.T. and Lievense , L.C. 1998 . Effect of Bifidobacterium longum and inulin on gut bacterial metabolism and carcinogen induced crypt foci in rats . Carcinogenesis. , 19 : 281 – 285 .
  • Pool-Zobel , B. , Van Loo , J. , Rowland , J. and Roberfroid , M. 2002 . Review of experimental evidence investigating the potential of prebiotic carbohydrates inulin and oligofructose to reduce the risk of colon cancer . Br. J. Nutr. , 87 : S273 – S281 .
  • Steer , T.E. and Gibson , G.R. 2002 . The microbiology of phytic acid metabolism by gut bacteria and relevance for bowel cancer. Int . J. Food Sci. Tech. , 37 : 783 – 790 .
  • Verghese , M. , Walker , L.T. , Shackelford , L. and Chawan , C.B. 2005 . Inhibitory effects of nondigestible carbohydrates ofdifferent chain lengths on azoxymethane-induced aberrant crypt foci in Fisher 344 rats . Nutr. Res. , 25 : 859 – 868 .
  • Hambly , R.J. , Saunders , M. , Rijken , P.J. and Rowland , I.R. 2002 . Influence of dietary components associated with high or low risk of colon cancer on apoptosis in the rat colon . Food Chem. Toxicol. , 40 : 801 – 808 .
  • Nzeusseu , A. , Dienst , D. , Haufroid , V. , Dpresseux , G. , Devoger , J.P. and Manicourt , D.H. 2006 . Inulin and fructo-oligosaccharides differ in their ability to enhance the density of cancellous and cortical bone in the axial and peripheral skeleton of growing rats . Bone. , 38 : 394 – 399 .
  • Gibson , G.R. and Wang , X. 1994 . Inhibitory effects of Bifidobacteria on other colonic bacteria . J. Appl. Bacteriol. , 65 : 103 – 111 .
  • Wang , X. 1993 . Comparative aspects of carbohydrate fermentation by colonic bacteria , Doctoral Thesis , , UK : University of Cambridge .
  • Cummings , J.H. , Christie , S. and Cole , T.J. 2001 . A study of fructooligosaccharides in the prevention of travellers’ diarrhoea . Aliment. Pharmacol.Ther. , 15 : 1139 – 1145 .
  • Macfarlane , S. , Macfarlane , G.T. and Cummings , J.H. 2006 . Review article: Prebiotics in the gastrointestinal tract . Aliment. Pharmacol. Ther. , 24 : 701 – 714 .
  • Aarsland , A. , Chinkens , D. and Wolfe , R.R. 1996 . Contributions of de novo synthesis of fatty acids to VLDL-triglyceride secretion during prolonged hyperglycemia/ hyperinsulinemia in normal man . J. Clin. Investig. , 98 : 2008 – 2017 .
  • Roberfroid , M.R. 2000 . Prebiotics and probiotics: are they functional foods? . Am. J. Clin. Nutr. , 71 ( suppl ) : 1682S – 1687S .
  • Franck , A. 2002 . Technological functionality of inulin and oligofructose . Br. J. Nutr. , 87 ( suppl. 2 ) : S287 – S291 .
  • Crittenden , R.G and Playne , M.J . 1996 . Production, properties, and applications of food-grade oligosaccharides . Trends Food Sci. Tech. , Nov ( 7 ) : 353 – 361 .
  • Devereux , H.M. , Jones , G.P. , McCormack , L. and Hunter , W.C. 2003 . Consumer acceptability of low fat foods containing inulin and oligofructose . J. Food Sci. , 68 ( 5 ) : 1850 – 1854 .
  • Gibson , G. R. 1998 . Dietary modulation of the human gur microflora using prebiotics . Br. J. Nutr. , 80 : S209 – S212 .
  • Roberfroid , M.B. , Gibson , G.R. and Delzenne , N. 1993 . Biochemistry of oligofructose, a non-digestible fructooligosaccharide: an approach to estimate its caloric value . Nutr. Rev. , 51 : 137 – 146 .
  • Roberfroid , M. 1993 . Dietary fiber, inulin, and oligofructose: A review comparing their physiological effects . Crit. Rev. Food Sci. Nutr. , 33 : 103 – 148 .
  • Hosoya , N. , Dhorranintra , B. and Hidaka , H. 1988 . Utilization of [U-14C]FOS in man as energy resources . J. Clin. Biochem. Nutr. , 5 : 67 – 74 .
  • Wiedmann , M. and Jager , M. 1997 . Synergistic sweeteners. Food Ingred . Anal. Int. November-December , : 51 – 56 .
  • de , Vuyst, L. 2000 . Technology aspects related to the application of functional starter cultures . Food Technol. Biotech. , 38 ( 2 ) : 105 – 112 .
  • Leveille , G.A. and Finley , J.W. 1997 . Macronutrient Substituents. Description and Uses . Ann. N. Y. Acad. Sci , May 23 ( 819 ) : 11 – 21 .
  • Cani , P.D. , Joly , E. , Horsmans , Y. and Delzenne , N.M. 2006 . Oligofructose promotes satiety in helathy human: a pilot study . Eur. J. Clin. Nutr. , 60 ( 5 ) : 567 – 572 .
  • Ipsen , R. , Otte , J. , Lozahic , G. and Ovist , K.B. 2001 . Microstructure and viscosity of yoghurt with inulin added as a fat replacer . Ann. Trans. Nord. Rheol. Soc. , 2000–2001 ( 8/9 ) : 59 – 62 .
  • Bozanic , R. , Rogelj , I. and Tratnik , L.J. 2001 . Fermented acidophilus goat's milk supplemented with inulin: comparison with cow's milk . Milchwissenschaft. , 56 ( 11 ) : 618 – 622 .
  • Hauly , M.C.O. , Fuchs , R.H.B. and Prudencio-Perreira , S.H. 2005 . Soymilk yogurt supplemented with fructo-oligosaccharides: probiotic properties and acceptance . Revista de Nutricao. , 18 ( 5 ) : 613 – 622 .
  • İbrahim , G.A. , Mehanna , N.S. , El-Rab , D.A.G. , Abd El-Salam , M.H , Kholif , A.M , Abdou , S.M. and El-Shibiny , S. Oct. 9–11 2004 . “ Preparation and properties of set fermented milk containing inulin and different probiotics ” . In 9th Egyptian Conference for Dairy Science and Technology , Oct. 9–11 , 117 – 132 . Cairo, Egypt : Egyptian Soc. Dairy Sci .
  • Hassan , F.A.M. , Helmy , W.A. and Enab , A.K. 1999 . Utilization of some local polysaccharide in manufacturing of yogurt . Egyptian J. Dairy Sci. , 27 ( 2 ) : 281 – 289 .
  • Guven , M. , Yasar , K. , Karaca , O.B. and Hayaloglu , A.A. 2005 . The effect of inulin as a fat replacer on the quality of set-type low-fat yogurt manufacture . Int. J Dairy Technol. , 58 ( 3 ) : 180 – 184 .
  • Dello Staffolo , M. , Bertola , N. , Martino , M. and Bevilacqua , A. 2004 . Influence of dietary fiber addition on sensory and rheological properties of yogurt . Int. Dairy J. , 14 ( 3 ) : 263 – 268 .
  • Sevdim , Z.B.G. , Sarikus , G. and Okur , O.D. 2005 . Effect of inulin and Dairy-Lo as fat replacers on the quality of set-type yogurt . Milchwissenschaft. , 60 ( 1 ) : 51 – 55 .
  • Hardi , J. and Slacanac , V. 2000 . Examination of coagulation kinetics and rheological properties of fermented milk products: the influence of starter culture, milk fat content and addition of inulin . Mijekartsvo. , 50 ( 3 ) : 217 – 226 .
  • Sadek , Z.I. , El-Shafei , K. and Murad , H.A. Oct. 9–11 2004 . “ Utilization of xanthan gum and inulin as prebiotics by lactic acid bacteria ” . In 9th Egyption Conference for Dairy Science and Technology , Oct. 9–11 , 269 – 283 . Cairo, Egypt : Egyptian Soc. Dairy Sci .
  • Shin , H.S. , Lee , J.H. , Pestka , J.J. and Ustunol , Z. 2000 . Growth and viability of commercial Bifidobacterium spp. in skim milk containing oligosaccharides and inulin . J. Food Sci. , 65 : 884 – 887 .
  • Praznik , W. , Ciéslik , E. and Filipiak-Florkiewicz , A. 2002 . Soluble dietary fibers in jerusalem artichoke powders: composition and application in bread . Nahrung/Food. , 46 ( 3 ) : 151 – 157 .
  • Aryana , K.J. , Plauche , S , Rao , R.M. , McGrew , P. and Shah , N.P. 2007 . Fat-free plain yogurt manufactured with inulins of various chain lengths and Lactobacillus acidophilus . J. Food Sci. , 72 ( 3 ) : M79 – M84 .
  • Vereyken , I.J. , Kuik , A. , Evers , T.H. , Rijken , P.J. and Kruijff , B. 2003 . Structural requirements of the fructan-lipid interaction . Biophys. J. , 84 : 3147 – 3154 .
  • Kruger , M.C. , Brown , K.E. , Collett , G. , Layton , L. and Schollum , M. 2003 . The effect of fructo-oligosaccharides with various degree of polymerization on calcium bioavailability in the growing rat . Exp. Biol. Med. , 228 : 663 – 668 .
  • Cho , Y.J. , Sinha , J. , Park , J.P. and Yun , J.W. 2001 . Production of inulo-oligosaccharides from inulin by a dual endoinulinase system . Enzyme Microb. Tech. , 29 : 428 – 433 .
  • Kim , D.H. , Choi , Y.J. , Song , S.K. and Yun , J.W. 1997 . Production of inulo-oligosaccharides using endo-inulinase from a Pseudomonas sp . Biotechnol. Lett. , 19 ( 4 ) : 369 – 371 .
  • Lewis , D.H. 1993 . Nomenclature and diagrammatic representation of oligomeric fructans-a paper for discussion . New Phytol. , 124 : 583 – 594 .
  • Bancal , P. , Henson , C. , Gaudillére , J.P. and Carpita , N.C. 1991 . Fructan chemical sturucture and sensitivity to exohydrolase . Carbohyd. Res. , 217 : 137 – 151 .
  • Waterhouse , A.L. and Chatterton , N.J. 1993 . “ Glossary of fructan terms ” . In Science and Technology of Fructans , Edited by: Suzuki , M. and Chatterton , N.J. 1 – 8 . Boca Raton, Fl : CRC Press .
  • Roberfroid , M.B. , Van Loo , J.A.E. and Gibson , G.R. 1998 . A review of the bifidogenic nature chicory inulin and its hydrolysis products . J. Nutr. , 128 : 1 – 19 .
  • Menne , E. and Guggenbuhl , N. December, 4-5 1997 . Prebiotic effect of the (fructosyl-1-fructose) Fm-type inulin hydrolysate in humans. NDO: Healthy Food for the Colon , December, 4-5 , 164 Wageningen : Sympossium LUW, Wageningen University .
  • Wang , X. and Gibson , G.R. 1993 . Effects of the in vitro fermentation of oligofructose and inulin by bacteria growing on the human large intestine . J. Appl. Bacteriol. , 75 : 373 – 380 .
  • Kullin , B. , Abrat , V. and Reid , S. 2006 . A functional analysis of Bifidobacterium longum cscA and scrP genes in sucrose utilization . Appl. Microbiol. Biot. , 72 ( 5 ) : 975 – 981 .
  • Muramatsu , K. , Onodera , S. , Kikuchi , M. and Shiomi , N. 1994 . Substrate specificity and subsite affinities of β-fructofuranosidase from Bifidobacterium adolescentis G1 . Biosci. Biotech. Biochem. , 58 ( 9 ) : 1642 – 1645 .
  • Sims , I.M. 2003 . Structural diversity of fructans from members of the order Asparagales in New Zealand . Phytochemistry. , 63 : 351 – 359 .
  • Benkeblia , N. , Onodera , S. and Shiomi , N. 2005 . Variation in 1-fructoexohydrolase (1-FEH) and 1-kestose hydrolysing (1-KH) activities and fructo-oligosaccharide status in onion bulbs. Influence of temperature and storage time . J. Sci. Food Agr. , 85 : 227 – 234 .
  • Fujishima , M. , Sakai , H. , Ueno , K. , Takahashi , N. , Onodera , S. , Benkeblia , N. and Shiomi , N. 2005 . Purification and characterization of a fructosyltransferase from onion bulbs and its key role in the synthesis of fructooligosaccharides in vivo . New Phytol. , 165 : 513 – 524 .
  • Benkeblia , N. , Ueno , K. , Onodera , S. and Shiomi , N. 2005 . Variation of FOSs and their metabolizing enzymes in onion bulb (Allium cepa L. cv. Tenshin) during long-term storage . J. Food Sci. , 70 ( 3 ) : S208 – S214 .
  • Shiomi , N. , Onodera , S. and Sakai , H. 1997 . Fructooligosaccharide content and fructosyltransferase activity during growth of onion bulbs . New. Phytol. , 136 : 105 – 113 .
  • Benkeblia , N. , Onodera , S. and Shiomi , N. 2004 . Effect of gamma irradiation and temperature on fructans (fructo-oligosaccharides) of stored onion bulbs Allium cepa L . Food Chem. , 87 : 377 – 382 .
  • Ueno , K. , Onodera , S. , Kawakami , A. , Yoshida , M. and Shiomi , N. 2005 . Molecular characterization and expression of cDNA encoding fructan:fructan 6G-fructosyltransferase from asparagus (Asparagus officinalis) . New Phytol. , 165 : 813 – 824 .
  • Timmermans , J.W. , Bitter , M.G.J.W. , deWitt , D. and Vliegenthart , J.F.G. 1997 . The interaction of inulin oligosaccharides with Ba2+ studied by H-1 NMR spectroscopy . J. Carbohydr. Chem. , 16 ( 2 ) : 213 – 230 .
  • De Leenheer , L. and Hoebregs , H. 1994 . Progress in the elucidation of the composition of chicory inulin . Starch/Starke. , 46 ( 5 ) : 193 – 196 .
  • Edelman , J. and Jefford , T.G. 1964 . The metabolism of fructose polymers in plants: beta-fructofuranosidases of tubers of Helianthus tuberosus L . New Phytol. , 93 : 148 – 161 .
  • Edelman , J. and Jefford , T.G. 1968 . The mechanism of fructan metabolism in higher plants exemplified in Helianthus tuberosus L . New Phytol. , 67 : 517 – 531 .
  • Nagaraj , V.J. , Altenbach , D. , Galati , V. , Luescher , M. , Meyer , A.D. , Boller , T. and Wiemken , A. 2004 . Distinct regulation of sucrose:sucrose 1-fructosyltransferase (1-SST) and sucrose: fructan-6-fructosyltransferase (6-SFT), the key enzymes of fructan synthesis in barley leaves: 1-SST as the pacemaker . New Phytol. , 161 : 735 – 748 .
  • Chalmers , J. , Johnson , X. , Lidgett , A. and Spangenberg , G. 2003 . Isolation andcharacterization of a sucrose:sucrose 1-fructosyltransferase gene from perennial ryegrass (Lolium perenne) . J. Plant Physiol. , 160 : 1385 – 1391 .
  • Hellwege , E.M. , Gritscher , D. , Willmitzer , L. and Heyer , A.G. 1997 . Transgenic potato tubers accumulate high levels of 1-kestose and nystose: functional identification of a sucrose:sucrose 1-fructosyltransferase of artichoke (Cynara scolymus) blossom disks . Plant J. , 12 : 1057 – 1065 .
  • Luescher , M. , Erdin , C. , Sprenger , N. , Hochstrasser , U. , Boller , T. and Wiemken , A. 1996 . Inulin synthesis by a combination of purified fructosyltransferases from tubers of Helianthus tuberosus . FEBS Lett. , 385 : 39 – 42 .
  • Koops , A.J. and Jonker , H.H. 1996 . Purification and characterization of the enzymes of fructan synthesis in tubers of Helianthus tuberosus Colombia. II. Purification of sucrose:sucrose 1-fructosyltransferase and reconstitution of fructan synthesis in vitro with purified sucrose:sucrose 1-fructosyltransferase and fructan:fructan 1-fructosyltransferase . Plant Physiol. , 110 : 1167 – 1175 .
  • Cairns , A.J. 1995 . Effects of enzyme concentration on oligofructan synthesis from sucrose . Pytochemistry. , 40 : 705 – 708 .
  • Van den Ende , W. , De Rover , J. and Van Laere , A. 1996 . In vitro synthesis of fructofuranosyl-only oligosaccharides from inulin and fructose by purified chicory root fructan:fructan fructosyltransferase . Physiol. Plant. , 97 : 346 – 352 .
  • Shiomi , N. and Izawa , M. 1980 . Purification and characterization of sucrose:sucrose 1-fructosyltransferase from the roots of Asparagus (Asparagus officinalis L.) . Agric. Biol. Chem. , 44 : 603 – 614 .
  • Satyanara , M.N. 1976 . Biosynthesis of oligosaccharides and fructans in Agave vera cruz. I. Properties of a partially purified transfructosylase . Indian. J. Biochem. Biophys. , 13 : 261 – 266 .
  • Yun , J.W. 1996 . Fructo-oligosaccharides-occurence, preparations and application . Enzyme Microb. Technol. , 19 : 107 – 117 .
  • Shiomi , N. , Kido , H. and Kiriyama , S. 1985 . Purification and properties of sucrose:sucrose 1F-beta-D-fructosyltransferase in onion seeds . Phytochemistry. , 24 : 695 – 698 .
  • Chevalier , P.M. and Rupp , R.A. 1993 . Inhibition of sucrose:sucrose fructosyltransferase by cationic and ionic strength . Plant Physiol. , 101 : 589 – 594 .
  • Henry , R.J. and Darbyshire , B. 1980 . Sucrose:sucrose fructosyltransferase and fructan:fructan fructosyltransferase from Allium cepa . Phytochemistry. , 19 : 1017 – 1020 .
  • Scott , R.W. , Jefford , T.G. and Edelman , J. 1966 . Sucrose fructosyltransferase from higher plant tissues. Biochem . J. , 100 : 23 – 24 .
  • Puebla , A.F. , Battaglia , M.E. , Salerno , G.L. and Pontis , H.G. 1999 . Sucrose:sucrose fructosyltransferase activity: A direct and rapid colorimetric procedure for the assay of plant extracts . Plant Physiol. , 37 : 699 – 702 .
  • Simmen , U. , Obenland , D. , Boller , T. and Wiemken , A. 1993 . Fructan synthesis in excised barley leaves. Identification of two sucrose:sucrose fructosyltransferases induced by light and their separation from constitutive invertases . Plant Physiol. , 101 : 459 – 468 .
  • Lüscher , M. , Hochstrasser , U , Boller , T. and Wiemken , A. 2000 . Isolation of sucrose:sucrose 1-fructosyltransferase (1-SST) from barley (Hordeum vulgare) . New Phytol. , 145 : 225 – 232 .
  • Roth , A. , Lüscher , M. , Sprenger , N. , Boller , T. and Wiemken , A. 1997 . Fructan and fructan metabolizing enzymes in the growth zone of barley . New Phytol. , 136 : 73 – 79 .
  • Dutchateau , N. , Bortlik , K. , Simmen , U. , Wiemken , A. and Bancal , P. 1995 . Sucrose:fructan 6-fructosyltransferase, a key enzyme for diverting sucrose to fructan in barley leaves . Plant Physiol. , 107 : 1249 – 1255 .
  • Sprenger , N. , Bortlik , K. , Brandt , A. , Boller , T. and Wiemken , A. 1995 . Purification, cloning and functional expression of sucrose:fructan 6-fructosyltransferase, a key enzyme of fructan synthesis in barley . Proc. Natl. Acad. Sci. USA , 92 : 11652 – 11656 .
  • Pavis , N. , Chatterton , N.J. , Harrison , P.A. , Baumgartner , S. , Praznik , W. , Boucaud , J. and Prud'homme , M.P. 2001 . Structure of fructans in roots and leaf tissues of Lolium perenne . New Phytol. , 150 : 83 – 95 .
  • Kawakami , A. and Yoshida , M. 2002 . Molecular characterization of sucrose:sucrose 1-fructosyltransferase and sucrose:fructan 6-fructosyltransferase associated with fructan accumulation in winter wheat during cold hardening . Biosci. Biotechnol. Biochem. , 66 : 2297 – 2305 .
  • Yang , J. , Zhang , J. , Wang , Z. , Zhou , Q. and Liu , L. 2004 . Activities of fructan- and sucrose-metobilizing enzymes in wheat stems subjected to water stress during grain filling . Planta. , 220 : 331 – 343 .
  • Van den Ende , W. and Van Laere , A. 1996 . De-novo synthesis of fructans from sucrose in vitro by a combination of two purified enzymes (sucrose:sucrose 1-fructosyltransferase and fructan:fructan 1-fructosyltransferase) from chicory roots (Cichorium intybus) . Planta. , 200 : 335 – 342 .
  • Van den Ende , W. , De Rover , J. and Van Laere , A. 1999 . Effect of nitrogen concentration on fructan and fructan metabolizing enzymes in young chicory plants (Cichorium intybus) . Physiol. Plant. , 105 : 2 – 8 .
  • Singh , R. and Bhatia , I.S. 1971 . Substrate specificity of fructosyltransferase from chicory roots . Phytochemistry. , 10 : 2037 – 2039 .
  • De Rover , J. , Vandenbranden , K. , Van Laere , A. and Van den Ende , W. 2000 . Drought induces fructan synthesis and 1-SST (sucrose:sucrose fructosyltransferase) in roots and leaves of chicory seedlings (Cichorium intybus L.) . Planta. , 210 : 808 – 814 .
  • De Halleux , S. and van Cutsem , P. 1997 . Cloning and sequencing of the 1-SST cDNA from chicory root . Plant Physiol. , 113 : 1003
  • Druart , N. , De Roover , J. , Van den Ende , W. , Goupil , P. , Van Laere , A. and Rambour , S. 2001 . Sucrose assimilation during early development stages of chicory (Cichorium intybus L.) plants . Planta. , 212 : 436 – 443 .
  • Praznik , W. , Beck , R.H.F. and Spies , T. 1990 . Isolation and characterization of sucrose:sucrose 1F-beta-D-fructosyltransferase from tubers of Helianthus tuberosus . Agric. Biol. Chem. , 54 : 2429 – 2431 .
  • Van der Meer , I.M. , Koops , A.J. and Hakkert , J.C. 1998 . Cloning of the fructan biosynthesis pathway of jerusalem artichoke . Plant J. , 15 : 489 – 500 .
  • Itaya , N.M. , Machado de Carvalho , M.A. and Figueiredo-Riberio , R.D.C.L. 2002 . Fructosyltransferase and hydrolase activities in rhizophores and tuberous roots upon growth of Polymnia sonchifolia (Asteraceae) . Physiol. Plant. , 116 : 451 – 459 .
  • Fukai , H. , Ohno , S. , Goto , K. , Nanjo , F. and Hara , Y. 1997 . Seasonal flactuations in fructant content and related enzyme activities in yacon (Polymnia sonchifolia) . Soil Sci. Plant Nutr. , 43 : 171 – 177 .
  • Van den Ende , W. and Van Laere , A. 1993 . Purification and properties of an invertase with sucrose:sucrose fructosyltransferase activity from the roots of Cichorium intybus L . New Phytol. , 123 : 31 – 37 .
  • Van den Ende , W. , Michiels , A. , Van Vonterghem , D. , Vergauwen , R. and Van Laere , A. 2000 . Cloning, developmental and tissue specific expression of sucrose:sucrose 1-fructosyltransferase from Taraxacum officinale. Fructan localization in roots . Plant Physiol. , 123 : 71 – 79 .
  • Portes , M.T. and Carvalho , M.A. 2006 . Spatial distribution of fructans and fructan metabolizing enzymes in rhizophores of Vernonia herbaceae (Vell.) Rusby (Asteraceae) in different developmental phases . Plant Sci. , 170 : 624 – 633 .
  • Itaya , N.M. , Figueiredo-Ribeiro , R.C.L. and Buckeridge , M.S. 1999 . Synthesis of fructans by fructosyltransferase from the roots of Viguierra discolor (Asteraceae) . Braz. J. Med. Biol. Res. , 32 : 435 – 442 .
  • Itaya , N.M. , Buckeridge , M.S. and Figueiredo-Ribeiro , R.C.L. 1997 . Biosynthesis in vitro of high-molecular-mass fructan by cell-free extracts from tuberous roots of Viguierra discolor (Asteraceae) . New Phytol. , 136 : 53 – 60 .
  • Ritsema , T. and Smeekens , S.C.M. 2003 . Engineering fructan metabolism in plants . J. Plant Physiol. , 160 : 811 – 820 .
  • Livingston III , D.P. 1991 . Non-structural carbohydrate accumulation in winter oat crowns before and during cold hardening . Crop Sci. , 31 : 751 – 755 .
  • Wang , C. and Tilberg , J.E. 1996 . Effect of nitrogen deficiency on accumulation of fructan metabolizing enzyme activities in sink and source leaves of barley (Hordeum vulgare) . New Phytol. , 136 : 131 – 135 .
  • Pilon-Smits , E.A.H. , Ebskamp , M.J.M. , Paul , M.J. , Jeuken , M.J.W. , Weisbeek , P.J. and Smeekens , S.C.M. 1995 . Improved performance of transgenic fructan-accumulating tobacco under drought stress . Plant Physiol. , 107 : 125 – 130 .
  • Hincha , D.K. , Hellwege , E.M. , Heyer , A.G. and Crowe , J.H. 2000 . Plant fructans stabilize phosphatidylcholine liposomes during freeze-drying . Eur. J. Biochem. , 297 : 535 – 540 .
  • St. John , J.A. , Bonnett , G.D. , Simpson , R.J. and Taner , G.J. 1997 . A fructan:fructan fructosyltransferase activity from Lolium rigidum . New Phytol. , 135 : 235 – 247 .
  • St. John , J.A. , Sims , I.M. , Bonnett , G.D. and Simpson , R.J. 1997 . Identification of products formed by a fructan:fructan fructosyltransferase activity from Lolium rigidum . New Phytol. , 135 : 249 – 257 .
  • Van den Ende , W. , Van Wonterghem , D. , Verhaert , P. , Dewil , E. and Van Laere , A. 1996 . Purification and characterization of fructan:fructan fructosyl transferase from chicory roots . Planta. , 199 : 493 – 502 .
  • Jeong , B.R. and Housley , T.L. 1992 . Purification and characterization of wheat β(2→1) fructan:fructan fructosyltransferase activity . Plant Physiol. , 100 : 199 – 204 .
  • Shiomi , N. 1982 . Purification and characterization of 1F-fructosyltransferase from the roots of asparagus (Asparagus officinalis L.) . Carbohydr. Res. , 99 : 157 – 169 .
  • Lüscher , M. , Frehner , M. and Noesberger , J. 1993 . Purification and some properties of fructan:fructan fructosyltransferase from Jerusalem artichoke (Helianthus tuberosus L.) . New Phytol. , 123 : 717 – 724 .
  • Benkeblia , N. , Onodera , S. and Shiomi , N. 2003 . Effect of temperature and storage time on fructosyltransferase activities (1-FFT and 6G-FFT) in onion bulb tissues . Acta Agric. Scand. Sect. B. , 53 : 211 – 214 .
  • Sĕvenier , R. , Van der Meer , I.M. , Bino , R. and Koops , A.J. 2002 . Increased production of nutriments by genetically engineered crops . J. Am. Collage of Nutrition. , 21 ( 3 ) : 199S – 204S .
  • Lüscher , M. , Frehner , M. and Nösberger , J. 1993 . Purification and some properties of fructan:fructan fructosyl transferase from dandelion (Taraxacum officinale Weber) . New Phytol. , 123 : 437 – 442 .
  • Van den Ende , W. , Mintiens , H. , Speleers , H. , Onuoha , A. and Van Laere , A. 1996 . The metabolism of fructansin roots of Cichorium intybus during growth, storage and forcing . New Phytol. , 132 : 555 – 563 .
  • Edelman , J. and Bacon , J.S.D. 1951 . Transfructosidation in extracts of the tubers of Helianthus tuberosus L . Biochem. J. , 49 : 529 – 540 .
  • Kawakami , A. and Yoshida , M. 2005 . Fructan:fructan 1-fructosyltransferase, a key enzyme for biosynthesis of graminan oligomers in hardened wheat . Planta. , 223 : 90 – 104 .
  • Vergauwen , R. , Van Laere , A. and Van den Ende , W. 2003 . Properties of fructan:fructan 1-fructosyltransferases from chicory and globe thistle, two asteracean plants storing greatly different types of inulin . Plant Physiol. , 133 : 391 – 401 .
  • Koops , A.J. and Jonker , H.H. 1994 . Purification and characterization of the enzymes of fructan biosynthesis in tubers of Helianthus tuberosus Colombia I. Fructan:fructan fructosyl transferase . J. Exp. Bot. , 45 : 1623 – 1631 .
  • Edelman , J. and Dickerson , A.G. 1966 . The metabolism of fructose polymers in plants. Transfructosylation in tubers of Helianthus tuberosus L . Biochem. J. , 98 : 787 – 794 .
  • Van den Ende , W. , Van Laere , A. , Le Roy , K. , Vergauwen , R. , Boogaerts , D. , Figueiredo-Ribeiro , R.C. and Machado de Carvalho , M.A. 2005 . Molecular cloning and characterization of a high DP fructan: Fructan 1-fructosyltransferase from Viguiera discolor (Asteraceae) and its heterologous expression in Pichia pastoris . Physiol. Plant. , 125 : 419 – 429 .
  • Lasseur , B. , Lothier , J. , Djoumad , A. , De Coninck , B. , Smeekens , S. , Van Laere , A. , Morvan-Bertrand , A. , Van den Ende , W. and Prudhomme , M.P. 2006 . Molecular and functional characterization of a cDNA encoding fructan:fructan 6G-fructosyltransferase (6G-FFT)/ fructan:fructan 1-fructosyltransferase (1-FFT) from perennial ryegrass (Lolium perenne L.) . J. Exp. Bot. , 57 : 2719 – 2734 .
  • Vijn , I. , Van Dijken , A. , Sprenger , N , Van Dun , K. , Weisbeek , P. , Wiemken , A. and Smeekens , S. 1997 . Fructan of the inulin neoseries is synthesized in transgenic chicory plants (Cichorium intybus L.) harbouring onion (Allium cepa L.) fructan:fructan 6G-fryctosyl transferase . Plant J. , 11 : 387 – 398 .
  • Ritsema , T. , Joling , J. and Smeekens , S. 2003 . Patterns of fructan synthesized by onion fructan:fructan 6G-fructosyltransferase expressed in tobacco BY2-cells-is fructan:fructan 1-fructosyltransferase needed in onion? . New Phytol. , 160 : 61 – 67 .
  • Shiomi , N. 1982 . Reverse reactions of fructosyl transfer catalyzed by asparagus 6G-fructosyltransferase . Carbohydr. Res. , 106 : 166 – 169 .
  • Wiemken , A. , Sprenger , N. and Boller , T. 1995 . “ Fructan extension of sucrose by sucrose ” . In Sucrose metabolism, biochemistry, physiology and molecular biology , Edited by: Pontis , H.G. , Salerno , G.L. and Echerverria , E.J. 178 – 189 . Rockville, M.D., USA : American Society of Plant Physiologists .
  • Vijn , I. and Smeekens , S. 1999 . Fructan: more than a reserve carbohydrate? . Plant Physiol. , 120 : 351 – 359 .
  • Shiomi , N. 1989 . Properties of fructosyltransferases involved in the synthesis of fructan in liliaceous plants . J. Plant Physiol. , 134 : 151 – 155 .
  • Shiomi , N. 1981 . Purification and characterization of 6G-fructosylransferase from the roots of asparagus (Asparagus officinalis L.) . Carbohydr. Res. , 96 : 281 – 292 .
  • Chatterton , N.J. and Harrison , P.A. 1997 . Fructan oligomers in Poa ampla . New Phytol. , 136 : 3 – 10 .
  • Koroleva , O.A. , Farrar , J.F. , Deri , T.A. and Pollock , C.J. 1998 . Carbohydrates in individual cells of epidermis, mesophyll, and bundle sheath in barley leaves with changed export or photosynthetic rate . Plant Physiol. , 118 : 1525 – 1532 .
  • Wang , C. , Van Den Ende , W. and Tillberg , J.E. 2000 . Fructan accumulation induced by nitrogen deficiency in barley leaves correlates with the level of sucrose:fructan 6-fructosyltransferase mRNA . Planta. , 211 : 701 – 707 .
  • Verhaest , M. , Van den Ende , W. , Le Roy , K. , De Ranter , J.C. , Van Laere , A. and Rabijns , A. 2005 . X-ray diffraction structure of a plant glycosyl hydrolase family 32 protein: fructan 1-exohydrolase IIa of Cichorium intybus . Plant J. , 41 : 400 – 411 .
  • Van den Ende , W. , Michiels , A. , De Rover , J. , Verhaert , P. and Van Laere , A. 2000 . Cloning and functional analysis of chicory root fructan 1-exohydrolase I (1-FEH I): a vacuolar enzyme derived from a cell-wall invertase ancestor? Mass fingerprint of the 1-FEH I enzyme . Plant J. , 24 : 447 – 456 .
  • Henson , C.A. and Livingston , D.P. III . 1996 . Purification and characterization of an oat fructan exohydrolase that preferentially hydrolyzes β-2,6-fructans . Plant Physiol. , 110 : 639 – 644 .
  • De Roover , J. , Van Laere , A. , De Winter , M. , Timmermans , J.W. and Van den Ende , W. 1999 . Purification and properties of a second fructan exohydrolase from the roots of Cichorium intybus . Physiol. Plant. , 106 : 28 – 34 .
  • Verhaest , M. , Van den Ende , W. , Yoshida , M. , Le Roy , K. , Peeraer , Y. , Sansen , S. , De Ranter , C.J. , Van Laere , A. and Rabijns , A. 2004 . Crystallization and preliminary X-ray diffraction study of fructan 1-exohydrolase IIa from Cichorium intybus . Acta Crystallogr. Scet.D. , 60 : 553 – 554 .
  • Michiels , A. , Van Laere , A. , Van den Ende , W. and Tucker , M. 2004 . Expression analysis of a chicory fructan 1-exohydrolase gene reveals complex regulation by cold . J. Exp. Bot. , 55 : 1325 – 1333 .
  • Van den Ende , W. , De Coninck , B. and Van Laere , A. 2004 . Plant fructan exohydrolases: a role in signaling and defense? . Trends Plant Sci. , 9 : 523 – 528 .
  • Le Roy , K. , Verhaest , M. , Rabijns , A. , Clerens , S. , Van Laere , A. and Van den Ende , W. 2007 . N-glycosylation affects substrate specificity of chicory fructan 1-exohydrolase: evidence for the presence of an inulin binding cleft . New Phytol. , 176 : 317 – 324 .
  • Van den Ende , W. , Michiels , A. , Van Wonterghem , D. , Clerens , S.P. , De Roover , J. and Van Laere , A.J. 2001 . Defoliation induces fructan 1-exohydrolase II in witloof chicory roots. Cloning and purification of two isoforms, fructan 1-exohydrolase IIa and fructan 1-exohydrolase IIb. Mass fingerprint of the fructan 1-exohydrolase II enzymes . Plant Physiol. , 126 : 1186 – 1195 .
  • Verhaest , M. , Lammens , W. , Le Roy , K. , De Ranter , C.J. , Van Laere , A. , Rabijns , A. and Van den Ende , W. 2007 . Insights into the fine architecture of the active site of chicory fructan 1-exohydrolase: 1-kestose as substrate vs sucrose as inhibitor . New Phytol. , 174 : 90 – 100 .
  • Le Roy , K. , Lammens , W. , Van Laere , A. and Van den Ende , W. 2008 . Influencing the binding configuration of sucrose in the active sites of chicory fructan 1-exohydrolase and sugar beet fructan 6-exohydrolase . New Phytol. , 178 : 572 – 580 .
  • Henson , C.A. and Livingstone III , D.P. 1998 . Characterization of a fructan exohydrolase purified from barley stems that hydrolyzes multiple fructofuranosidic linkages . Plant Physiol. Biochem. , 36 : 715 – 720 .
  • Frehner , M. , Keller , F. and Wiemken , A. 1984 . Localisation of fructan metabolism in the vacuoles isolated from protoplasts of jerusalem artichoke tubers (Helianthus tuberosus L.) . J. Plant Physiol. , 116 : 197 – 208 .
  • Lothier , J. , Lasseur , B. , Le Roy , K. , Van Laere , A. , Prudhmme , M.P. , Barre , P. , Van den Ende , W. and Morvan-Bertrand , A. 2007 . Cloning, gene mapping, and functional analysis of a fructan 1-exohydrolase (1-FEH) from Lolium perenne implicated in fructan synthesis rather than in fructan mobilization . J. Exp. Bot. , 58 : 1969 – 1983 .
  • Narai-Kanayama , A. , Tokita , N. and Aso , K. 2007 . Dependence of fructooligosaccharide content on activity of fructooligosaccharide-metabolizing enzymes in yacon (Smallanthus sonchifolius) tuberous roots during storage . J. Food Sci. , 72 : S381 – S387 .
  • Van den Ende , W. , Clerens , S. , Vergauwen , R. , Van Riet , L. , Van Laere , A. , Yoshida , M. and Kawakami , A. 2003 . Fructan 1-exohydrolases. β-(2,1)-trimmers during graminan biosynthesis in stems of wheat? Purification, characterization, mass mapping, and cloning of two fructan 1-exohydrolase isoforms . Plant Physiol. , 131 : 621 – 631 .
  • Kawakami , A. , Yoshida , M. and Van den Ende , W. 2005 . Molecular cloning and functional analysis of a novel 6&1-FEH from wheat (Triticum aestivum L.) preferentially degrading small graminans like bifurcose . Gene. , 358 : 93 – 101 .
  • Van Riet , L. , Nagaraj , V. , Van den Ende , W. , Clerens , S. , Wiemken , A. and Van Laere , A. 2006 . Purification, cloning and functional characterization of a fructan 6-exohydrolase from wheat (Triticum aestivum L.) . J. Exp. Bot. , 57 : 213 – 223 .
  • Paludan-Muller , C. , Gram , L. and Rattray , F.P. 2002 . Purification and characterisation of an extracellular fructan β-fructosidase from a Lactobacillus pentosus strain isolated from fermented fish . Syst. Appl. Microbiol. , 25 : 13 – 20 .
  • Uzunova , K. , Vassileva , A. , Kambourova , M. , Ivanova , V. , Spasova , D. , Mandeva , R. , Derekova , A. and Tonkova , A. 2001 . Production and properties of a bacterial thermostable exo-inulinase . Z. Naturforsch. C. , 56 : 1022 – 1028 .
  • Pressey , R. and Avants , J.K. 1980 . Invertases in oat seedlings . Plant Physiol. , 65 : 135 – 140 .
  • Krishnan , H.B. , Blanchette , J.T. and Okita , T.W. 1985 . Wheat invertases. Characterization of cell wall-bound and soluble forms . Plant Physiol. , 78 : 241 – 245 .
  • Obenland , D.M. , Simmen , U. , Boller , T. and Wiemken , A. 1993 . Purification and characterization of three soluble invertases from barley (Hourdeum vulgare L.) leaves . Plant Physiol. , 101 : 1331 – 1339 .
  • Fotopoulos , V. 2005 . Plant invertases: structure, function, and regulation of a diverse enzyme family . J. Biol. Res. , 4 : 127 – 137 .
  • Roitsch , T. and Gonzales , M.C. 2004 . Function and regulation of plant invertases: sweet sensations . Trends Plant Sci. , 9 : 606 – 613 .
  • Rausch , T. and Greiner , S. 2004 . Plant protein inhibitors of invertases . Biochim. Biophys. Acta. , 1696 : 253 – 261 .
  • Benkeblia , N. , Onodera , S. , Yoshihira , T. , Kosoka , S. and Shiomi , N. 2004 . Effect of temperature on soluble invertase activity, and glucose, fructose and sucrose status of onion bulbs (Allium cepa) in store . Int. J. Food Sci. Nutr. , 55 : 325 – 331 .
  • Goupil , P. , Croisille , Y. , Croisille , F. and Ledoigt , G. 1988 . Jerusalem artichoke invertases-immunocharacterization of a soluble form and its putative precursor . Plant Sci. , 54 : 45 – 54 .
  • Hendry , G.A.F. and Wallace , R.K. 1993 . “ The origin, distribution, and evolutionary significance of fructans ” . In Science and Technology of Fructans , Edited by: Suzuki , M. and Chatterton , N.J. 119 – 139 . Boca Raton, FL : CRC Press .
  • Darwen , C.W.E. and John , P. 1989 . Localisation of the enzymes of fructan metabolism in vacuoles isolated by a mechanical method from tubers of Jerusalem artichoke (Helianthus tuberosus L.) . Plant Physiol. , 89 : 658 – 663 .
  • Hendry , G.A.F. 1993 . Evolutionary origins and natural functions of fructans – a climatological, biogeographic and mechanistic appraisal . New Phytol. , 123 : 3 – 14 .
  • Yoshida , M. , Abe , J. , Moriyama , M. and Kuwabara , T. 1998 . Carbohydrate levels among winter wheat cultivars varying in freezing tolerance and snow mold resistance during autumn and winter . Physiologia Plantarum , 103 : 8 – 16 .
  • Pollock , C. , Farrar , J. , Tomos , D. , Gallagher , J. , Lu , C. and Koroleva , O. 2003 . Balancing supply and demand: the spatial regulation of carbon metabolism in grass and cereal leaves . J. Exp. Bot. , 54 : 489 – 494 .
  • Suzuki , M. 1993 . “ Fructans in crop production and preservation ” . In Science and Technology of Fructans , Edited by: Suzuki , M. and Chatterton , N.J. 228 – 255 . Boca Raton, FL : CRC Press .
  • Livingston , D.P. III , Chatterton , N.J. and Harrison , P.A. 1993 . Structure and quantity of fructan oligomers in oat (Avena spp.) . New Phytol. , 123 : 725 – 734 .
  • Kolida , S. and Gibson , G.R. 2008 . “ The prebiotic effect: Review of experimental and human data ” . In Handbook of Prebiotics , Edited by: Gibson , G.R. and Roberfroid , M.B. 39 – 69 . Boca Raton, FL : CRC Press .
  • Ohyama , T. , Ito , O. , Yasuyoshi , S. , Ikarashi , T. , Minamisawa , K. , Kubota , M. , Tsukihashi , T. and Asami , T. 1990 . Composition of storage carbohydrates in tubers of yacon (Polymnia sonchifolia) . Soil Sci. Plant. Nutr. , 36 : 167 – 171 .
  • Cairns , A.J. and Pollock , C.J. 1988 . Fructan biosynthesis in excised leaves of Lolium temulentum L. I. Chromatographic characterization of oligofructans and their labeling patterns following 14CO2 feeding . New Phytol. , 109 : 399 – 405 .
  • Sims , I.M. , Pollock , C.J. and Horgan , R. 1992 . Structural analysis of oligomeric fructans from excised leaves of Lolium temulentum L . Phytochemistry. , 31 : 2989 – 2992 .
  • Chatterton , N.J. , Harrison , P.A. , Thornley , W.R. and Bennett , J.H. 1993 . Structure of fructan oligomers in orchard grass (Dactylis glomerata L.) . J. Plant Physiol. , 142 : 552 – 556 .
  • Bancal , P. , Carpita , N.C. and Gaudillĕre , J.P. 1992 . Differences in fructan accumulated in induced and field grown wheat plants: an elongation trimming pathway for their synthesis . New Phytol. , 120 : 313 – 321 .
  • Duchateau , N. , Bortlik , K. , Simmen , U. , Wiemken , A. and Bancal , P. 1995 . Sucrose:fructan 6-fructosyltransferase (6-SFT), a key enzyme for diverting carbon from sucrose to fructan in barley leaves . Plant Physiol. , 107 : 1249 – 1255 .
  • Bravo , L.A. , Ulloa , N. , Zuffiga , G.E. , Casanova , A. , Corcuera , L.J. and Alberdi , M. 2001 . Cold resistance in Antarctic angiosperms . Physiologia Plantarum , 111 : 55 – 65 .
  • Schütz , K. , Muks , E. , Carle , R. and Schieber , A. 2006 . Separation and quantification of inulin in selected artichoke (Cynara scolymus L.) cultivars and dandelion (Taraxacum officinale WEB. Ex WIGG.) roots by high-performance anion exchange chromatography with pulsed amperometric detection . Biomed. Chromatog. , 20 : 1295 – 1303 .
  • Machado de Carvalho , M.A. , Zaidan , L.B.P. and Dietrich , S.M.C. 1997 . Growth and fructan content of plants of Vernonia herbacea (Asterceae) regenerated from rhizophores . New Phytol. , 136 : 153 – 161 .
  • Sims , I.M. , Cairns , A.J. and Furneaux , R.H. 2001 . Structure of fructans from excised leaves of New Zealand flax . Phytochemistry , 57 : 661 – 668 .
  • Shiomi , N. 1993 . Structure of fructopolysaccharide (asparagosin) from roots of asparagus (Asparagus officinalis L.) . New Phytol. , 123 : 263 – 270 .
  • Jaime , L. , Martines , F. , Martin-Cabrejas , M.A. , Mollă , E. , Lopĕz-Andrĕu , F.J. , Waldron , K.W. and Esteban , R.M. 2000 . Study of total fructan and fructo-oligosaccharide content in different onion tissues . J. Sci. Food Agr. , 81 : 177 – 182 .
  • Orthen , B. and Wehrmeyer , A. 2004 . Seasonal dynamics of non-structural cabohydrates in bulbs and shoots of the geophyte Gallanthus nivalis . Physiologia Plantarum , 120 : 529 – 536 .
  • Graefe , S. , Hermann , M. , Manrique , I. , Golombek , S. and Burkert , A. 2004 . Effects of post-harvest treatments on the carbohydrate composition of yacon roots in the Peruvian Andes . Field Crops Research , 86 : 157 – 165 .
  • Yıldız , S. 2006 . Production of sweetening syrups with functional properties , Ankara, Turkey : PhD Thesis. Chemical Engineering Department, Middle East Technical University .
  • Chabbert , N. , Braun , P. , Guiraud , J.P. , Arnoux , M. and Galzy , P. 1983 . Productivity and fermentability of jerusalem artichoke according to harvest date . Biomass. , 3 : 209 – 224 .
  • Benkeblia , N. , Varoquaux , P. , Gouble , B. and Selselet-Attou , G. 2000 . Respiratory parameters of onion bulbs. Effects of irradiation and temperature . J. Sci. Food Agr. , 80 : 1772 – 1778 .
  • Valentovă , K. and Ulrichovă , J. 2003 . Smallanthus sonchifolius and lepidium meyenii – prospective Andean crops for the prevention of chronic diseases . Biomed Papers. , 147 ( 2 ) : 119 – 130 .
  • Merendino , N. , D'Aquino , M. , Molinari , R. , De Gara , L. , D'Egidio , M.G. , Paradiso , A. , Cecchini , C. , Corradini , C. and Tomassi , G. 2006 . Chemical characterization and biological effects of immature drum wheat in rats . J. Cereal Sci. , 43 : 129 – 136 .
  • Schnyder , H. 1993 . The role of carbohydrate storage and redistribution in the source-sink relations of wheat and barley during grain filling – a review . New Phytol. , 123 : 233 – 245 .
  • Bancal , P. and Triboii , E. 1993 . Temperature effect on fructan oligomer contents and fructan-related enzyme activities in stems of wheat (Triticum aestivum L.) during grain filling . New Phytol. , 123 : 247 – 253 .
  • Benkeblia , N. , Varoquaux , P. , Shomi , N. and Sakai , H. 2002 . Effects of irradiation, MH and CIP treatments on respiration rate and oligosaccharide variation in onion bulbs in store . Int. J. Food Sci. Technol. , 37 : 169 – 176 .
  • Benkeblia , N. and Varoquaux , P. 2003 . Effect of gamma irradiation, temperature and storage time on glucose, fructose and sucrose statues of onion bulbs Allium cepa L . International Agrophysics , 17 : 1 – 5 .
  • Cabezas , M.J. , Rabert , C. , Bravo , S. and Shene , C. 2002 . Inulin and sugar contents in Helianthus tuberosus and Cichorium intybus tubers: Effect of post-harvest storage temperature . Food Chem. Toxicol. , 67 ( 8 ) : 2860 – 2865 .
  • Ernst , M. , Chatterton , N.J. and Harrison , P.A. 1995 . Carbohydrate changes in chicory (Cichorium intybus L. var. Foliosum) during growth and storage . Sci. Horticult. , 63 : 251 – 261 .
  • Benkeblia , N. , Shiomi , N. and Osaki , M. 2007 . Kinetics and hydrolysis parameters of total fructo-oligosaccharides of onion bulbs: Effects of temperature regimes and cultivars . J. Food Biochem. , 31 : 14 – 27 .
  • Jaime , L. , Martin-Cabrejas , M.A. , Mollă , E. , Lopĕz-Andrĕu , F.J. and Esteban , R.M. 2001 . Effect of storage on fructan and fructo-oligosaccharide of onion (Allium cepa L.) . J. Agric. Food Chem. , 49 : 982 – 988 .
  • Blecker , C. , Fougnies , C. , Van Herk , J.C. , Chevalier , J.P. and Paquot , M. 2002 . Kinetic study of the acid hydrolysis of various oligofructose samples . J. Agric. Food Chem. , 50 : 1602 – 1607 .
  • Benkeblia , N. , Takahashi , N. , Ueno , K. , Onodera , S. and Shiomi , N. 2005 . Tetra- and penta- fructooligosaccharide (FOS) isomers assessment in onion bulb tissues. Effect of temperature and storage time . Tetrahedron: Asymmetry. , 16 : 33 – 37 .
  • Shiomi , N. , Yamada , J. and Izawa , M. 1976 . Isolation and identification of fructo-oligosaccharides in root of asparagus (Asparagus officinalis L.) . Agric. Biol. Chem. , 40 : 567 – 575 .
  • Shiomi , N. , Yamada , J. and Izawa , M. 1979 . A novel pentasaccharide in the roots of asparagus (Asparagus officinalis L.) . Agric. Biol. Chem. , 43 : 1375 – 1377 .
  • Shiomi , N. 1981 . Two novel hexasaccharides from the roots of Asparagus officinalis . Phytochemistry , 20 : 2581 – 2583 .
  • Chatterton , N.J. , Harrison , P.A. , Thornley , W.R. and Bennett , J.H. 1993 . Structure of fructan oligomers in cheatgrass (Bromus tectorum L.) . New Phytol. , 124 : 389 – 396 .
  • Chatterton , N.J. , Harrison , P.A. , Thornley , W.R. and Draper , E.A. 1990 . Oligosaccharides in foliage of Agropyron, Bromus, Dactylis, Festuca, Lolium and Phleum . New Phytol. , 114 : 167 – 171 .
  • Marx , S.P. , Nösberger , J. and Frehner , M. 1997 . Seasonal variation of fructan-β-fructosidase (FEH) activity and characterization of a β-(2,1)-linkage specific FEH from tubers of jerusalem artichoke (Helianthus tuberosus L.) . New Phytol. , 135 : 267 – 277 .
  • Brasch , D.J. , Fankhauser , B.L. and McDonald , A.G. 1988 . A study of the glycofructofuranan from the New Zealand cabbage tree Cordyline australis . Carbohydr Res. , 180 : 315 – 324 .
  • Carvalho , M.A.M. and Dietrich , S.M.C. 1993 . Variation in fructan content in the underground organs of Vernonia herbacea (vell.) Rusby at different phenological phases . New Phyt. , 123 : 735 – 740 .
  • Isejima , E.M. and Figuerido-Ribeiro , R.C.L. 1993 . Fructan variations in tuberous roots of Viguierra discolor Baker (Asteraceae): the influence of phenology . Plant Cell Physiol. , 34 : 723 – 727 .
  • Housley , T.L. and Volenec , J.J. 1988 . Fructan content and synthesis in leaf tissue of Festuca arundinacea . Plant Physiol. , 86 : 1247 – 1251 .
  • Morvan-Bertrand , A. , Pavis , N. , Boucaud , J. and Prud'homme , M.P. 1999 . Partitioning of reserve and new assimilated carbon in roots and leaf tissues of Lolium perenne during regrowth after defoliation: assessment by 13C-steady-state labeling and carbohydrate analysis . Plant Cell Environ. , 22 : 1097 – 1108 .
  • Saulnier , D.M.A. , Molenaar , D. , de Vos , W.M. , Gibson , G.R. and Kolida , S. 2007 . Identification of prebiotic fructooligosaccharide metabolism in Lactobacillus plantarum WCFS1 through microarrays . Appl. Environ. Microbiol. , 73 ( 6 ) : 1753 – 1765 .
  • Suzuki , N. , Aiba , Y. , Takeda , H. , Fukumori , Y. and Koga , Y. 2006 . Superiority of 1-kestose, the smallest fructo-oligosaccharide, to a synthetic mixture of fructo-oligosaccharides in the selective stimulating activity on Bifidobacteria . Bioscience Microflora. , 25 ( 3 ) : 109 – 116 .
  • Chambert , R. and Petit-Glatron , M.F. 1991 . Polymerase and hydrolase activities of Bacillus subtilis levansucrase can be separately modulated by site-directed mutagenesis . Biochem. J. , 279 : 35 – 41 .

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