6
Views
1
CrossRef citations to date
0
Altmetric
Original Article

CCL2 Transgene Expression in the Central Nervous System Directs Diffuse Infiltration of CD45highCD11b+Monocytes and Enhanced Theiler's Murine Encephalomyelitis Virus–Induced Demyelinating Disease

, , , , &
Pages 623-636 | Published online: 10 Jul 2009

References

  • Aubert C, Brahic M (1995). Early infection of the central nervous system by the GDVII and DA strains of Theiler's virus. J Virol 69: 3197–3200.
  • Baggiolini M (1998). Chemokines and leukocyte traffic. Nature 392: 565–568.
  • Berman JW, Guida MP, Warren J, Amat J, Brosnan CF (1996). Localization of monocyte chemoattractant peptide-1 ex-pression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat. J Immuno1156: 3017–3023.
  • Boring L, Gosling J, Monteclaro FS, Lusis AJ, Tsou CL, Charo IF (1996). Molecular cloning and functional ex-pression of murine JE (monocyte chemoattractant pro-tein 1) and murine macrophage inflammatory pro-tein la receptors-evidence for two closely linked C-C chemokine receptors on chromosome 9. JBiol Chem 271: 7551–7558.
  • Brautigam AR, Dutko FJ, Olding LB, Oldstone MB (1979). Pathogenesis of murine cytomegalovirus infection: the macrophage as a permissive cell for cytomegalovirus in-fection, replication and latency. J Gen Virol 44: 349–359.
  • Brenner M, Kisseberth WC, Su Y, Besnard F, Messing A (1994). GFAP promoter directs astrocyte-specific expres-sion in transgenic mice. J Neurosci 14: 1030–1037.
  • Brocke S, Piercy C, Steinman L, Weissman IL, Veromaa T (1999). Antibodies to CD44 and integrin a4, but not L-selectin, prevent central nervous system inflamma-tion and experimental encephalomyelitis by blocking secondary leukocyte recruitment. Proc Nati Acad Sci USA 96: 6896–6901.
  • Carr MW, Roth SJ, Luther E, Rose SS, Springer TA (1994). Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant. Proc Natl Acad Sci USA 91: 3652–3656.
  • Chen BP, Kuziel WA, Lane TE (2001). Lack of CCR2 results in increased mortality and impaired leukocyte activa-tion and trafficking following infection of the central nervous system with a neurotropic coronavirus. J Im-munol 167: 4585–4592.
  • Clatch RJ, Lipton HL, Miller SD (1986). Characterization of Theiler's murine encephalomyelitis virus (TMEV)-specific delayed-type hypersensitivity responses in TMEV- induced demyelinating disease: correlation with clinical signs. J Immunol 136: 920–927.
  • Clatch RJ, Miller SD, Metzner R, Dal Canto MC, Lipton HL (1990). Monocytes/macrophages isolated from the mouse central nervous system contain infec-tious Theiler's murine encephalomyelitis virus (TMEV). Virology 176: 244–254.
  • Cochran BH, Reffel AC, Stiles CD (1983). Molecular cloning of gene sequences regulated by platelet-derived growth factor. Cell 33: 939–947.
  • Dal Canto MC, Lipton HL (1975). Primary demyelination in Theiler's virus infection. An ultrastructural study. Lab Invest 33: 626–637.
  • DeGrendele HC, Kosfiszer M, Estess P, Siegelman MH (1997). CD44 activation and associated primary adhe-sion is inducible via T cell receptor stimulation. J Im-muno1159: 2549–2553.
  • Fife BT, Huffnagle GB, Kuziel WA, Karpus WJ (2000). CC Chemokine receptor 2 is critical for induction of experi-mental autoimmune encephalomyelitis. J Exp Med 192: 899–906.
  • Fife BT, Paniagua MC, Lukacs NW, Kunkel SL, Karpus WJ (2001). Selective CC chemokine receptor expres-sion by central nervous system-infiltrating encephali-togenic T cells during experimental autoimmune en-cephalomyelitis. J Neurosci Res 66: 705–714.
  • Fuentes ME, Durham SK, Swerdel MR, Lewin AC, Barton DS, Megill JR, Bravo R, Lira SA (1995). Controlled recruitment of monocytes and macrophages to spe-cific organs through transgenic expression of monocyte chemoattractant protein- 1. J Immunol 155: 5769–5776.
  • Glabinski AR, Tani M, Strieter RM, Tuohy VK, Ransohoff RM (1997). Synchronous synthesis of a- and /3-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic exper-imental autoimmune encephalomyelitis. Am J Pathol 150: 617–630.
  • Glabinski AR, Tuohy VK, Ransohoff RM (1998). Ex-pression of chemokines RANTES, MIP-1alpha and GRO-alpha correlates with inflammation in acute ex-perimental autoimmune encephalomyelitis. Neuroim-munomodulation 5: 166–171.
  • Gu L, Tseng S, Homer RM, Tam C, Loda M, Rollins BJ (2000). Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1. Nature 404: 407–411.
  • Hoffman LM, Fife BT, Begolka WS, Miller SD, Karpus WJ (1999). Central nervous system chemokine expression during Theiler's virus-induced demyelinating disease. J NeuroVirol 5: 635–642.
  • Huang D, Tani M, Wang J, Han Y, He TT, Weaver J, Charo IF, Tuohy VK, Rollins BJ, Ransohoff RM (2002). Pertussis toxin-induced reversible encephalopathy dependent on monocyte chemoattractant protein-1 overexpression in mice. J Neurosci 22: 10633–10642.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.