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Research Article

Branching Out: A Molecular Fingerprint of Endothelial Differentiation into Tube-Like Structures Generated by Affymetrix Oligonucleotide Arrays

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Pages 63-81 | Published online: 10 Jul 2009

REFERENCES

  • Abou-Mohamed GA, Huang J, Oldham CD, Taylor TA, Jin L, Caldwell RB, May SW, Caldwell RW. (2000). Vascular and endothelial actions of inhibi-tors of substance P arnidation. J Cardiovasc Phar-macol 35:871–880.
  • Ackermann EJ, Taylor JK, Narayana R, Bennett CF. (1999). The role of antiapoptotic Bc1-2 family mem-bers in endothelial apoptosis elucidated with anti-sense oligonucleotides . J Biol Chem 274:11245–11252.
  • Adra CN, Zhu S, Ko JL, Guillemot JC, Cuervo AM, Kobayashi H, Horiuchi T, Lelias JM, Rowley JD, Lim B. (1996). LAPTM5: A novel lysosomal-associated multispanning membrane protein prefer-entially expressed in hematopoietic cells. Genomics 35:328–337.
  • Antohe F, Popov D, Radulescu L, Sirnionescu N, Borchers T, Spener F, Sirnionescu M. (1998). Heart microvessels and aortic endothelial cells express the 15 kDa heart-type fatty acid-binding proteins. Eur J Cell Biol 76:102–109.
  • Aoki M, Kanarnori M, Yudoh K, Ohrnori K, Yasuda T, Kimura T. (2001). Effects of vascular endothelial growth factor and E-selectin on angiogenesis in the murine metastatic RCT sarcoma. Tumour Biol 22: 239–246.
  • Barron-Casella EA, Torres MA, Scherer SW, Heng HIFI, Tsui LC, Casella JF. (1995). Sequence analysis and chromosomal localization of human Cap Z. Conserved residues within the actin-binding domain may link Cap Z to gelsolin/severin and profilin pro-tein families. J Biol Chem 270:21472–21479.
  • Bayless KJ, Salazar R, Davis GE. (2000). RGD-dependent vacuolation and lumen formation ob-served during endothelial cell morphogenesis in three-dimensional fibrin matrices involves the al-pha(v)beta(3) and alpha(5)beta(1) integrins. Am J Pathol 156:1673–1683.
  • Bird IN, Taylor V, Newton JP, Spragg JH, Simmons DL, Salmon M, Buckley CD. (1999). Homophilic PECAM-1(CD31) interactions prevent endothelial cell apoptosis but do not support cell spreading or migration. J Cell Sci 112:1989–1997.
  • Bischoff J, Brasel C, Kraling B, Vranovska K. (1997). E-selectin is upregulated in proliferating en-dothelial cells in vitro. Microcirculation 4:279–287.
  • Black RA. (2002). Tumor necrosis factor-alpha con-verting enzyme. Jut J Biochem Cell Biol 34:1–5.
  • Bolivar J, Guelrnan S, Iglesias C, Ortiz M, Valdivia 1VIVI. (1998). The fragile-X-related gene FXR1 is a human autoantigen processed during apoptosis. J Biol Chem 273:17122–17127.
  • Brinkmann U, Brinkmann E, Bera TK, Wellrnann A, Pastan I. (1999).Tissue-specific alternative splicing of the CSE1L/CAS (cellular apoptosis susceptibil-ity) gene. Genomics 58:41–49.
  • Brooks PC, Clark RA, Cheresh DA. (1994). Require-ment of vascular integrin alpha v beta 3 for angio-genesis. Science 264:569–571.
  • Brooks PC, Montgomery AM, Rosenfeld M, Reisfeld RA, Hu T, Mier G, Cheresh DA. (1994). Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79:1157–1164.
  • Brooks PC, Stromblad S, Memke R, Visscher D, Sarkar FH, Cheresh DA. (1995). Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin [see comments]. J Clin Invest 96:1815–1822.
  • Chen Q, Baird SD, Mahadevan M, Besner-Johnston A, Farahani R, Xuan J, Kang X, Lefebvre C, Ikeda JE, Korneluk RG, MacKenzie AE. (1998). Sequence of a 131-kb region of 5q13.1 containing the spinal muscular atrophy candidate genes SMIN and NAIP. Genomics 48:121–127.
  • Chiu DS, Orarn JF, LeBoeuf RC, Alpers CE, O'Brien KB. (1997). High-density lipoprotein-binding pro-tein (HBP)/vigilin is expressed in human atheroscle-rotic lesions and colocalizes with apolipoprotein E. Arterioscler Thromb Vasc Biol 17:2350–2358.
  • Corasaniti MT, Piccirilli S, Paoletti A, Nistico R, Stringaro A, Malorni W, Finazzi-Agro A, Bagetta G. (2001). Evidence that the HIV-1 coat protein gp120 causes neuronal apoptosis in the neocortex of rat via a mechanism involving CXCR4 chemokine receptor. Neurosci Lett 312:67–70.
  • Das R, Harnrnarnieh R, Neill R, Melhem M, Jett M. (2001). Expression pattern of fatty acid-binding proteins in human normal and cancer prostate cells and tissues. Clin Cancer Res 7:1706–1715.
  • Davis G, Pintar Allen K, Salazar R, Maxwell S. (2001). Matrix metalloproteinase-1 and -9 activa-tion by plasmin regulates a novel endothelial cell- mediated mechanism of collagen gel contraction and capillary tube regression in three-dimensional colla-gen matrices. J Cell Sci 114:917–930.
  • Davis GE, Camarillo CW. (1996). An alpha 2 beta 1 integrin-dependent pinocytic mechanism involving intracellular vacuole formation and coalescence regulates capillary lumen and tube formation in three-dimensional collagen matrix. Exp Cell Res 224:39–51.
  • Delikouras A, Hayes M, Malde P, Lechler RI, Dor-ling A. (2001). Nitric oxide-mediated expression of Bc1-2 and Bc1-xl and protection from tumor necrosis factor-alpha-mediated apoptosis in porcine endo-thelial cells after exposure to low concentrations of xenoreactive natural antibody. Transplantation 71: 599–605.
  • DeLisser FIIIVI, Christofidou-Solomidou M, Strieter RM, Burdick MD, Robinson CS, Wexler RS, Kerr JS, Garlanda C, Merwin JR, Madri JA, Albelda SM. (1997). Involvement of endothelial PECA1V1-1/CD31 in angiogenesis. Am J Pathol 151:671–677.
  • Drake CJ, Cheresh DA, Little CD. (1995). An an-tagonist of integrin alpha v beta 3 prevents matu-ration of blood vessels during embryonic neovascu-larization. J Cell Sci 108:2655–2661.
  • Duriez PJ, Wong F, Dorovini-Zis K, Shahidi R, Kar-san A. (2000). Al functions at the mitochondria to delay endothelial apoptosis in response to tumor ne-crosis factor. J Biol Chem 275:18099–18107.
  • Emanueli C, Minasi A, Zacheo A, Chao J, Chao L, Sails MB, Straino S, Tozzi MG, Smith R, Gaspa L, Bianchini G, Stillo F, Capogrossi MC, Madeddu P. (2001). Local delivery of human tissue kallikrein gene accelerates spontaneous angiogenesis in mouse model of hindlirnb ischemia. Circulation 103:125–132.
  • Emanueli C, Sails MB, Stacca T, Gaspa L, Chao J, Chao L, Piana A, Madeddu P. (2001). Rescue of impaired angiogenesis in spontaneously hyperten-sive rats by intramuscular human tissue kallikrein gene transfer. Hypertension 38:136–141.
  • Evans PC, Kilshaw PJ. (2000). Interleukin-13 pro-tects endothelial cells from apoptosis and activation: association with the protective genes A20 and Al. Transplantation 70:928–934.
  • Felbor U, Dreier L, Bryant RA, Ploegh HL, Olsen BR, Mothes W. (2000). Secreted cathepsin L gener-ates endostatin from collagen XVIII. E114130 J 19: 1187–1194.
  • Friedlander M, Brooks PC, Shaffer RW, Kincaid CM, Varner JA, Cheresh DA. (1995). Definition of two angiogenic pathways by distinct alpha v inte-grins. Science 270:1500–1502.
  • Furusu A, Nakayama K, Xu Q, Konta T, Sugiyama H, Kitarnura M. (2001). Expression, regulation, and function of inhibitor of apoptosis family genes in rat mesangial cells. Kidney Int 60:579–586.
  • Georgakopoulos A, Mararnbaud P, Efthirniopoulos S, Shioi J, Cui W, Li HC, Schutte M, Gordon R, Holstein GR, Martinelli G, Mehta P, Friedrich VL, Jr., Robakis NK. (1999). Presenilin-1 forms com-plexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts. Mol Cell 4:893–902.
  • Georgakopoulos A, Mararnbaud P, Friedrich VL Jr., Shioi J, Efthirniopoulos S, Robakis NK. (2000). Pre-senilin-1: A component of synaptic and endothelial adherens junctions. Ann N Y Acad Sci 920:209–214.
  • Gerber HP, Dixit V, Ferrara N. (1998). Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bc1-2 and Al in vascular en-dothelial cells. J Biol Chem 273:13313–13316.
  • Gerritsen ME. (1996). Physiological and patho-physiological roles of eicosanoids in the microcircu-lation. Cardiovasc Res 32:720–732.
  • Gerritsen ME, Shen CP, Atkinson WJ, Padgett RC, Girnbrone MA Jr, Milstone DS. (1996). Microvascu-lar endothelial cells from E-selectin-deficient mice form tubes in vitro. Lab Invest 75:175–184.
  • Goepfert C, Irnai M, Brouard S, Csizmadia E, Kacz-marek E, Robson SC. (2000). CD39 modulates en-dothelial cell activation and apoptosis. Mol Med 6: 591–603.
  • Gonzalez FJ, Fernandez-Salguero P. (1998). The aryl hydrocarbon receptor: studies using the AHR-null mice. Drug Metab Dispos 26:1194–1198.
  • Griffith EC, Su Z, Turk BE, Chen S, Chang YH, Wu Z, Biemann K, Liu JO. (1997). Methionine amino-peptidase (type 2) is the common target for angio-genesis inhibitors AGM-1470 and ovalicin. Chem Biol 4:461–471.
  • Gurnienny TL, Brugnera E, Tosello-Trarnpont AC, Kinchen ym, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS. (2001). CED -12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phago-cytosis and cell migration. Cell 107:27–41.
  • Haas TL, Davis SJ, Madri JA. (1998). Three-dimensional type I collagen lattices induce coordi-nate expression of matrix metalloproteinases MT1-1VEVIP andlVEVIP-2 in microvascular endothelial cells. J Biol Chem 273:3604–3610.
  • Hartwell DW, Butterfield CE, Frenette PS, Kenyon BM, Hynes RO, Folkman J, Wagner DD. (1998). Angiogenesis in P- and E-selectin-deficient mice. Microcirculation 5:173–178.
  • Hazan RB, Phillips GR, Qiao RF, Norton L, Aaron-son SA. (2000). Exogenous expression of N-cad-herin in breast cancer cells induces cell migration, invasion, and metastasis. J Cell Biol 148:779–790.
  • Herold C, Ganslrnayer M, Ocker M, Hermann M, Geerts A, Hahn EG, Schuppan D. (2002). The his- tone-deacetylase inhibitor Trichostatin A blocks proliferation and triggers apoptotic programs in hepatoma cells. J Hepatol 36:233–240.
  • Izawa I, Nishizawa M, Ohtakara K, Inagaki M. (2002). Densin-180 interacts with delta-catenin/ neural plakophidin-related armadillo repeat protein at synapses. J Biol Chem 277:5345–5350.
  • Jow F, Sullivan K, Sokol P, Nurnann R. (1999). Induction of Ca2+-activated K+ current and tran-sient outward currents in human capillary endothe-lial cells. J Membr Biol 167:53–64.
  • Kadono Y, Shibahara K, Namiki M, Watanabe Y, Seiki M, Sato H. (1998). Membrane type 1-matrix metalloproteinase is involved in the formation of hepatocyte growth factor/scatter factor-induced branching tubules in madin-darby canine kidney epithelial cells. Biochem Biophys Res Commun 251: 681–687.
  • Kannan K, Stewart RM, Bounds W, Carlsson SR, Fukuda M, Betzing KW, Holcombe RF. (1996). Ly-sosome-associated membrane proteins h-LA1VIP1 (CD107a) and h-LAMP2 (CD107b) are activation-dependent cell surface glycoproteins in human pe-ripheral blood mononuclear cells which mediate cell adhesion to vascular endothelium. Cell Immunol 171:10–19.
  • Kawakami A, Tian Q, Duan X, Streuli M, Schloss-man SF, Anderson P. (1992). Identification and functional characterization of a TIA-1-related nu-cleolysin. Proc Natl Acad Sci USA 89:8681–8685.
  • Kim CS, Wang T, Madri JA. (1998). Platelet endo-thelial cell adhesion molecule-1 expression modu-lates endothelial cell migration in vitro. Lab Invest 78:583–590.
  • Kim KW, Bae SK, Lee OH, Bae MH, Lee MJ, Park BC. (1998). Insulin-like growth factor II induced by hypoxia may contribute to angiogenesis of human hepatocellular carcinoma. Cancer Res 58:348–351.
  • Koch AE, Halloran 1VEVI, Haskell CJ, Shah MR, Pol-verini PJ. (1995). Angiogenesis mediated by soluble forms of E-selectin and vascular cell adhesion mol-ecule-1. Nature 376:517–519.
  • Kondo A, Suzuki K. (1993). The blood brain barrier in human leukodystrophies and allied diseases: Ultrastructural and morphometric studies on the capillaries in brain biopsies. Clin Neuropathol 12: 169–174.
  • Kondo S, Yin D, Aoki T, Takahashi JA, Morirnura T, Takeuchi J. (1994). bc1-2 gene prevents apoptosis of basic fibroblast growth factor-deprived murine aor-tic endothelial cells. Exp Cell Res 213:428–432.
  • Kraling BM, Razon MJ, Boon LM, Zurakowski D, Seachord C, Darveau RP, Mulliken JIB, Corless CL, Bischoff J. (1996). E-selectin is present in prolifer-ating endothelial cells in human hemangiomas. Am J Pathol 148:1181–1191.
  • Kunapuli P, Gurevich VV, Benovic JL. (1994). Phospholipid-stimulated autophosphorylation acti- vates the G protein-coupled receptor kinase GRK5. J Biol Chem 269:10209–10212.
  • Lee OH, Bae SK, Bae MH, Lee YM, Moon EJ, Cha HJ, Kwon YG, Kim KW. (2000). Identification of angiogenic properties of insulin-like growth factor II in in vitro angiogenesis models. Br J Cancer 82:385–391.
  • Liang XH, Jackson S, Seaman M, Brown K, Kemp-kes B, Hibshoosh H, Levine B. (1999). Induction of autophagy and inhibition of turnorigenesis by beclin 1. Nature 402:672–676.
  • Lopez-Perez E, Zhang Y, Frank SJ, Creemers J, Sei-dah N, Checler F. (2001). Constitutive alpha-secretase cleavage of the beta-arnyloid precursor protein in the furin-deficient LoVo cell line: involve-ment of the pro-hormone convertase 7 and the dis-integrin metalloprotease ADAM10. J Neurochem 76: 1532–1539.
  • Maltepe E, Schmidt JV, Baunoch D, Bradfield CA, Simon MC. (1997). Abnormal angiogenesis and re-sponses to glucose and oxygen deprivation in mice lacking the protein ARNT. Nature 386:403–407.
  • Markus MA, Reichrnuth C, Atkinson MJ, Reich U, Hoffmann I, Balling R, Anderer U, Hoder H. (1999). Cadherin-11 is highly expressed in rhabdo-myosarcomas and during differentiation of myo-blasts in vitro. J Pathol 187:164–172.
  • Mechtersheirner S, Gutwein P, Agmon-Levin N, Stoeck A, Oleszewski M, Riedle S, Fogel M, Lemmon V, Altevogt P. (2001). Ectodomain shedding of Li adhesion molecule promotes cell migration by auto-crine binding to integrins. J Cell Biol 155:661–673.
  • Meyer GT, Matthias LJ, Noack L, Vadas MA, Gamble JR. (1997). Lumen formation during angio-genesis in vitro involves phagocytic activity, forma-tion and secretion of vacuoles, cell death, and cap-illary tube remodelling by different populations of endothelial cells. Anat Rec 249:327–340.
  • Munro SB, Turner IM, Farookhi R, Blaschuk OW, Jothy S. (1995). E-cadherin and OB-cadherin mRNA levels in normal human colon and colon car-cinoma. Exp Mol Pathol 62:118–122.
  • Murphy AN, Unsworth EJ, Steder-Stevenson WG. (1993). Tissue inhibitor of metalloproteinases-2 in-hibits bFGF-induced human microvascular endo-thelial cell proliferation. J Cell Physiol 157:351–358.
  • Noble KE, Wickremasinghe RG, DeCornet C, Pa-nayiotidis P, Yong KL. (1999). Monocytes stimulate expression of the Bc1-2 family member, Al, in en-dothelial cells and confer protection against apopto-sis. J Immunol 162:1376–1383.
  • Nor JE, Christensen J, Liu J, Peters M, Mooney DJ, Strieter RM, Polverini PJ. (2001). Up-Regulation of Bc1-2 in microvascular endothelial cells enhances in-tratumoral angiogenesis and accelerates tumor growth. Cancer Res 61: 2183–2188.
  • Nor JE, Christensen J, Mooney DJ, Polverini PJ. (1999). Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bc1-2 expression. Am J Pathol 154: 375–384.
  • Ohneda O, Ohneda K, Arai F, Lee J, Miyamoto T, Fukushirna Y, Dowbenko D, Lasky LA, Suda T. (2001). ALCA1VI (CD166): Its role in hematopoietic and endothelial development. Blood 98: 2134–2142.
  • Okura T, Gong L, Karnitani T, Wada T, Okura I, Wei CF, Chang HM, Yeh ET. (1996). Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrin. J Immunol 157:4277–4281.
  • Oldham CD, Li C, Girard PR, Nerem RM, May SW. (1992). Peptide arnidating enzymes are present in cultured endothelial cells. Biochem Biophys Res Commun 184:323–329.
  • Otani H, Yarnamura T, Nakao Y, Hattori R, Fujii H, Ninomiya H, Kido M, Kawaguchi H, Osako M, Imamura H, Ohta T, Ohkurna S. (2000). Vacuolar H(+)-ATPase plays a crucial role in growth and phenotypic modulation of myofibroblasts in cul-tured human saphenous vein. Circulation 102: 111269–111274.
  • Pishvaian MJ, Feltes CM, Thompson P, Bussemak-ers MJ, Schalken JA, Byers SW. (1999). Cadherin-11 is expressed in invasive breast cancer cell lines. Cancer Res 59:947–952.
  • Porcu P, Emanueli C, Kapatsoris M, Chao J, Chao L, Madeddu P. (2002). Reversal of angiogenic growth factor upregulation by revascularization of lower limb ischemia. Circulation 105:67–72.
  • Premont RT, Koch WJ, Inglese J, Lefkowitz RJ. (1994). Identification, purification, and character-ization of GRK5, a member of the family of G pro-tein-coupled receptor kinases. J Biol Chem 269: 6832–6841.
  • Puyrairnond A, Weitzman JIB, Babiole E, Menashi S. (1999). Examining the relationship between the ge-latinolytic balance and the invasive capacity of en-dothelial cells. J Cell Sci 112:1283–1290.
  • Rando OJ, Zhao K, Jaruney P, Crabtree GR. (2002). Pho sphatidylino sitol - dep en de nt actin filament binding by the SWI/SNF-like BAF chromatin re-modeling complex. Proc Natl Acad Sci USA 99: 2824–2829.
  • Rempel SA, Dudas S, Ge S, Gutierrez JA. (2000). Identification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to re-gions of necrosis and angiogenesis in human glib-blastoma. Clin Cancer Res 6:102–111.
  • Robert EG, Hunt JD. (2001). Lipid messengers as targets for antiangiogenic therapy. Curr Pharm Des 7:1615–1626.
  • Rocha E, Mahiou J, Badrichani AZ, Stroka DM, Fer-ran, C. (2001). The BH4 domain of Al, an anti-apoptotic bcl family gene, is necessary and sufficient for its antiinflarnmatory function in endothelial cells. Transplant Proc 33:314.
  • Rodrigo JP, Garcia LA, Ramos S, Lazo PS, Suarez C. (2000). EMS1 gene amplification correlates with poor prognosis in squamous cell carcinomas of the head and neck. Clin Cancer Res 6:3177–3182.
  • Roof DJ, Hayes A, Adarnian M, Chishti MI, Li T. (1997). Molecular characterization of abLIM, a novel actin-binding and double zinc finger protein. J Cell Biol 138:575–588.
  • Sahni M, Raz R, Coffin JD, Levy D, Basilico C. (2001). STAT1 mediates the increased apoptosis and reduced chondrocyte proliferation in mice over-expressing FGF2. Development 128:2119–2129.
  • Schnaper HV/, Grant DS, Stetler-Stevenson WG, Fridman R, D'Orazi G, Murphy AN, Bird RE, Hoythya M, Fuerst TR, French DL, Quigley JP, Kleinman HK. (1993). Type IV collagenase(s) and TIVIPs modulate endothelial cell morphogenesis in vitro. J Cell Physiol 156:235–246.
  • Shariat-Madar Z, Mahdi F, Schmaier AH. (2002). Identification and characterization of prolylcar-boxypeptidase as an endothelial cell prekallikrein activator. J Biol Chem 277:17962–9.
  • Sheibani N, Frazier WA. (1999). Thrombospondin-1, PECAM-1, and regulation of angiogenesis. Histol Histopathol 14:285–294.
  • Shibata T, Ochiai A, Gotoh M, Machinarni R, Hiro-hashi S. (1996). Simultaneous expression of cad-herin-11 in signet-ring cell carcinoma and stromal cells of diffuse-type gastric cancer. Cancer Lett 99: 147–153.
  • Solito E, Raguenes-Nicol C, de Coupade C, Bisagni-Faure A, Russo-Marie F. (1998). U937 cells de-prived of endogenous annexin 1 demonstrate an in-creased PLA2 activity. Br J Pharmacol 124:1675–1683.
  • Song J, Takeda M, Morimoto RI. (2001). Bagl-Hsp70 mediates a physiological stress signalling pathway that regulates Raf-1/ERK and cell growth. Nat Cell Biol 3:276–282.
  • Sourlingas TG, Tsapali DS, Kaldis AD, Sekeri-Pataryas E. (2001). Histone deacetylase inhibitors induce apoptosis in peripheral blood lymphocytes along with histone H4 acetylation and the expres-sion of the linker histone variant, H1 degrees. Eur J Cell Biol 80:726–732.
  • Stroka DM, Badrichani AZ, Bach FH, Ferran C. (1999). Overexpression of Al, an NF-kappaB-in-ducible anti-apoptotic bcl gene, inhibits endothelial cell activation. Blood 93:3803–3810.
  • Tanahashi H, Tabira T. (1999). Isolation of human delta-catenin and its binding specificity with prese-nilin 1. Neuroreport 10:563–568.
  • Tortoriello DV, Sidis Y, Holtzman DA, Holmes WE, Schneyer AL. (2001). Human follistatin-related protein: A structural homologue of follistatin with nuclear localization. Endocrinology 142:3426–3434.
  • Toyooka KO, Toyooka S, Virmani AK, Sathyana-rayana UG, Euhus DM, Gilcrease M, Minna JD, Gaz-dar AF. (2001). Loss of expression and aberrant methylation of the CDH13 (H-cadherin) gene in breast and lung carcinomas. Cancer Res 61:4556–4560.
  • Turk BE, Griffith EC, Wolf S, Biemann K, Chang YH, Liu JO. (1999). Selective inhibition of amino-terminal methionine processing by TNP-470 and ovalicin in endothelial cells. Chem Biol 6:823–833.
  • Vaca L, Licea A, Possani LD. (1996). Modulation of cell membrane potential in cultured vascular endo-thelium. Am J Physiol 270: C819–C824.
  • van Kempen LC, Nelissen JM, Degen WG, Torensma R, Weidle UH, Bloemers HP, Figdor CG, Swart GW. (2001). Molecular basis for the homophilic activated leukocyte cell adhesion molecule (ALCA1VI)-ALCA1V1 interaction. J Biol Chem 276:25783–25790.
  • Weis M, Heeschen C, Glassford AJ, Cooke JP. (2002). Statins have biphasic effects on angiogene-sis. Circulation 105:739–745.
  • Williams RJ. (2001). Trichostatin A, an inhibitor of histone deacetylase, inhibits hypoxia-induced angio-genesis. Expert Opin Investig Drugs 10:1571–1573.
  • Wirth B, Herz M, Wetter A, Moskau S, Hahnen E, Rudnik-Schoneborn S, Wienker T, Zerres K. (1999). Quantitative analysis of survival motor neu-ron copies: identification of subtle S1VIN1 mutations in patients with spinal muscular atrophy, genotype-phenotype correlation, and implications for genetic counseling. Am J Hum Genet 64:1340–1356.
  • Wyder L, Vitaliti A, Schneider H, Hebbard LW, Moritz DR, Wittmer M, Ajmo M, Klemenz R. (2000). Increased expression of H/T-cadherin in tu-mor-penetrating blood vessels. Cancer Res 60: 4682–4688.
  • Xin X, Yang S, Ingle G, Zlot C, Rangell L, Kowalski J, Schwall R, Ferrara N, Gerritsen M. (2001). He-patocyte growth factor enhances vascular endothe-lial growth factor-induced angiogenesis in vitro and in vivo. Am J Pathol 158:1111–1120.
  • Yang S, Graham J, Kahn J, Schwartz E, Gerritsen M. (1999). Differential roles for CD31 and VE-cad-herin in formation of vascular tubes and lumens in three dimensional collagen gels. Am J Pathol 155: 887–895.
  • Yang S, Graham J, Kahn JW, Schwartz EA, Gerrit-sen ME. (1999). Functional roles for PECA1VI-1(CD31) and VE-cadherin (CD144) in tube assembly and lumen formation in three-dimensional collagen gels. Am J Pathol 155:887–895.
  • Yang S, Xin X, Zlot C, Ingle G, Fuh G, Li B, Moffat B, de Vos AM, Gerritsen ME. (2001). Vascular en-dothelial cell growth factor-driven endothelial tube formation is mediated by vascular endothelial cell growth factor receptor-2, a kinase insert domain-containing receptor. Arterioscler Thromb Vasc Biol 21:1934–1940.
  • Yu W, Liu J, Morrice NA, Wettenhall RE. (1997). Isolation and characterization of a structural homo-logue of human PRK2 from rat liver: Distinguishing substrate and lipid activator specificities. J Biol Chem 272:10030–10034.
  • Zannettino AC, Buhring HJ, Niutta S, Watt SM, Benton MA, Simmons PJ. (1998). The sialomucin CD164 (MGC-24v) is an adhesive glycoprotein ex-pressed by human hematopoietic progenitors and bone marrow stromal cells that serves as a potent negative regulator of hematopoiesis. Blood 92: 2613–2628.
  • Zhong Y, Delgado Y, Gomez J, Lee SW, Perez-Soler R. (2001). Loss of H-cadherin protein expression in human non-small cell lung cancer is associated with tumorigenicity. . Clin Cancer Res 7:1683–1687.
  • Zhou M, Graham R, Russell G, Croucher PI. (2001). MDC-9 (ADAM-9/Meltrin gamma) functions as an adhesion molecule by binding the alpha(v)beta(5) integrin. Biochem Biophys Res Commun 280:574–580.
  • Zong WX, Edelstein LC, Chen C, Bash J, Gelinas C. (1999). The prosurvival Bc1-2 homolog Bf1-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis. Genes Dev 13: 382–387.
  • Zukowska-Grojec Z, Karwatowska-Prokopczuk E, Rose W, Rone J, Movafagh S, Ji H, Yeh Y, Chen WT, Kleinman HK, Grouzmann E, Grant DS. (1998). Neuropeptide Y: A novel angiogenic factor from the sympathetic nerves and endothelium. Circ Res 83: 187–195.
  • Zurnbrunn J, Trueb B. (1996). Primary structure of a putative serine protease specific for IGF-binding proteins. FERS Lett 398:187–192.
  • Zwad O, Kubler B, Roth W, Scharf JG, Saftig P, Peters C, Braulke T. (2002). Decreased intracellular degradation of insulin-like growth factor binding protein-3 in cathep sin L-deficient fibroblasts. FERS Lett 510:211–215.

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