Neutrophils Induce Sequential Focal Changes in Endothelial Adherens Junction Components: Role of Elastase

REFERENCES

• Allport JR, Muller WA, Luscinskas FW. (2000). Monocytes induce reversible focal changes in vascular endothelial cadherin complex during transendothelial migration under flow. J Cell Biol 148:203–216.
   Google Scholar
• Aplin AE, Howe A, Alahari SK, Juliano RE. (1998). Signal transduction and signal modulation by cell ad-hesion receptors: the role of integrins, cadherins, im-munoglobulin-cell adhesion molecules, and selectins. Pharmacol Rev 50:197–263.
   PubMed Web of Science ®Google Scholar
• Berman ME, Muller WA. (1995). Ligation of platelet/ endothelial cell adhesion molecule 1 (PECAM-1/ CD31) on monocytes and neutrophils increases bind-ing capacity of leukocyte CR3 (CD11b/CD18). J Im-munol 154:299–307.
   PubMed Web of Science ®Google Scholar
• Burns AR, Walker DC, Brown ES, Thurmon LT, Bowden RA, Keese CR, Simon SI, Entman ML, Smith CW. (1997). Neutrophil transendothelial migration is independent of tight junctions and occurs preferen-tially at tricellular corners. J Immunol 159:2893–2903.
   PubMed Web of Science ®Google Scholar
• Carden D, Xiao F, Moak C, Willis BH, Robinsonjackson S, Alexander S. (1998). Neutrophil elastase promotes lung microvascular injury and proteolysis of endothe-lial cadherins. Am J Physiol 44:H385–H392.
   Google Scholar
• Carlos TM, Harlan JM. (1994). Leukocyte-endo-thelial adhesion molecules. Blood 84:2068–2101.
   PubMed Web of Science ®Google Scholar
• Cepinskas G, Noseworthy R, Kvietys PR. (1997). Transendothelial neutrophil migration: Role of neu-trophil-derived proteases and relationship to transen-dothelial protein movement. Circ Res 81:618–626.
   Google Scholar
• Cepinskas G, Noseworthy R, Kvietys PR. (1997). Transendothelial neutrophil migration: Role of neu-trophil-derived proteases and relationship to transen-dothelial protein movement. Circ Res 81:618–626.
   Google Scholar
• Cepinskas G, Sandig M, Kvietys PR. (1999). PAF-induced elastase-dependent neutrophil transendothe-lial migration is associated with the mobilization of elastase to the neutrophil surface and localization to the migrating front. J Cell Sci 112:1937–1945.
   Google Scholar
• Cotran RS, Mayadas-Norton T. (1998). Endothelial adhesion molecules in health and disease. Pathol Biol (Paris) 46:164–170.
   PubMedGoogle Scholar
• Dejana E, Valiron O, Navarro P. Lampugnani MG. (1997). Intercellular junctions in the endothelium and the control of vascular permeability. Ann N Y Acad Sci 811:36–43.
   Google Scholar
• Del Maschio A, Zanetti A, Corada M, Rival Y, Ruco L, Lampugnani MG, Dejana E. (1996). Polymorpho-nuclear leukocyte adhesion triggers the disorganiza-tion of endothelial cell-to-cell adherens junctions. J Cell Biol 135:497–510.
   PubMed Web of Science ®Google Scholar
• Etienne-Manneville S, Manneville JB, Adamson P. Wilbourn B, Greenwood J, Couraud PO. (2000). ICAM-1 coupled cyto skeletal rearrangements and transendothelial lymphocyte migration involve intra-cellular calcium signaling in brain endothelial cell lines. J Immunol 165:3375–3383.
   PubMedGoogle Scholar
• Feng D, Nagy JA, Pyne K, Dvorak HF, Dvorak AM. (1998). Neutrophils emigrate from venules by a transendothelial cell pathway in response to FMLP. J Exp Med 187:903–915.
   PubMedGoogle Scholar
• Furie MB, Naprstek BL, Silverstein SC. (1987). Mi-gration of neutrophils across monolayers of cultured microvascular endothelial cells: An in vitro model of leukocyte extravasation. J Cell Sci 88:161–175.
   Google Scholar
• Gahmberg CG, Valmu L, Kotovuori A, Kotovuori P. Bilden TJ, Fagerholm S, Kantor C, Nurminen T, Iha-nus E, Tian L. (1999). Leukocyte adhesion: An inte-grated molecular process at the leukocyte plasma membrane. Biosci Rep 19:273–281.
   Google Scholar
• Garcia JN, Verin AD, Herenyiova M, English D. (1998). Adherent neutrophils activate endothelial myosin light chain kinase: Role in transendothelial migration. J Appl Physiol 84:1817–1821.
   PubMedGoogle Scholar
• Gautam N, Hedqvist P. Lindbom L. (1998). Kinetics of leukocyte-induced changes in endothelial barrier function. Br J Pharmacol 125:1109–1114.
   Google Scholar
• Ginzberg HG, Cherapanov V, Dong Q, Cantin A, Mc-Culloch CAG, Shannon PT, Downey GP. (2001). Neutrophil-mediated epithelial injury during trans-migration: role of elastase. Am J Physiol 281:G705–G717.
   Google Scholar
• Gotsch U, Borges E, Bosse R, Boggemeyer E, Simon M, Mossmann H, Vestweber D. (1997). VE-cadherin antibody accelerates neutrophil recruitment in vivo. J Cell Sci 110:583–588.
   PubMed Web of Science ®Google Scholar
• Granger DN, Kubes P. (1994). The microcirculation and inflammation: modulation of leukocyte-endothelial cell adhesion. JLeukoc Biol 55:662–675.
   PubMed Web of Science ®Google Scholar
• Granger DN, Yuan SY. Zawieja DC. (2000). Ultra-structural basis of leukocyte migration through the microvascular membrane. In: Granger DN, Schmid-Schonbein GW, editors. Physiology and Pathophysi-ology of Leukocyte Adhesion. New York: Oxford Uni-versity Press, p 185–216.
   Google Scholar
• Gulino D, Delachanal E, Concord E, Genoux Y, Morand B, Valiron MO, Sulpice E, Scaife R, Alemany M, Vernet T. (1998). Alteration of endothelial cell monolayer integrity triggers resynthesis of vascular endothelium cadherin. J Biol Chem 273:29786–29793.
   PubMedGoogle Scholar
• Gurubhagavatula I, Amrani Y, Pratico D, Ruberg FL, Albelda SM, Panettieri RA, Jr. (1998). Engagement of human PECAM-1 (CD31) on human endothelial cells increases intracellular calcium ion concentration and stimulates pro stacyclin release. J Clin Invest 101: 212–222.
   PubMed Web of Science ®Google Scholar
• Hordijk PL, Anthony E, Mul FJ, Rientsma R, Oomen LM, Roos D. (1999). Vascular-endothelial-cadherin modulates endothelial monolayer permeability. J Cell Sci 112:1915–1923.
   PubMed Web of Science ®Google Scholar
• Huang AJ, Manning JE, Bandak TM, Ratau MC, Han-ser KR, Silverstein SC. (1993). Endothelial cell cyto-solic free calcium regulates neutrophil migration across monolayers of endothelial cells. J Cell Biol 120: 1371–1380.
   PubMed Web of Science ®Google Scholar
• Huber AR, Weiss SJ. (1989). Disruption of the sub-endothelial basement membrane during neutrophil diapedesis in an in vitro construct of a blood vessel wall. J Clin Invest 83:1122–1136.
   PubMed Web of Science ®Google Scholar
• Ilan N, Mahooti S, Rimm DL, Madri JA. (1999). PE-CAM-1 (CD31) functions as a reservoir for and a modulator of tyrosine-phosphorylated beta-catenin. J Cell Sci 112:3005–3014.
   PubMed Web of Science ®Google Scholar
• Ionescu CV, Cepinskas G, Savickiene J, Kvietys PR. (2001). Sequential recovery of endothelial adherens junctions components after PMN transendothelial mi-gration (abstract). FASEB J 15:A831.
   Google Scholar
• Kishimoto TK, Jutila MA, Berg EL, Butcher EC. (1989). Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factors. Science 245:1238–1241.
   PubMed Web of Science ®Google Scholar
• Kvietys PR, Cepinskas G, Granger DN. (1996). Neu-trophil-endothelial cell interactions during ischemia/ reperfusion. In: Kamada T, Shiga T, McCuskey RS, editors. Tissue Reperfusion and Organ function: Is-chemia/Reperfusion Injury. Amsterdam: Elsevier, p 179–191.
   Google Scholar
• Kvietys PR, Granger DN. (1997). Endothelial cell monolayers as a tool for studying microvascular pathophysiology. Am J Physiol 273:G1189–G1199.
   Google Scholar
• Kvietys PR, Sandig M. (2001). Neutrophil diapedesis: Paracellular or transcellular. News Physiol Sci 16:15–19.
   Google Scholar
• Lampugnani MG, Corada M, Andriopoulou P. Esser S, Risau W, Dejana E. (1997). Cell confluence regu-lates tyrosine phosphorylation of adherens junction components in endothelial cells. J Cell Sci 110:2065–2077.
   Google Scholar
• Lampugnani MG, Corada M, Caveda L, Breviario F, Ayalono, Geiger B, Dejana E. (1995). The molecular organization of endothelial cell to cell junctions: dif-ferential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin). J Cell Biol 129:203–217.
   PubMed Web of Science ®Google Scholar
• Lampugnani MG, Dejana E. (1997). Interendothelial junctions: Structure, signalling and functional roles. Curr Opin Cell Biol 9:674–682.
   PubMed Web of Science ®Google Scholar
• Lindner JR, Kahn ML, Coughlin SR, Sambrano GR, Schauble E, Bernstein D, Foy D, Hafezi-Moghadam A, Ley K. (2000). Delayed onset of inflammation in protease-activated receptor-2- deficient mice. J Im-munol 165:6504–6510.
   PubMed Web of Science ®Google Scholar
• Luu NT, Rainger GE, Nash GB. (1999). Kinetics of the different steps during neutrophil migration through cultured endothelial monolayers treated with tumour necrosis factor-alpha. J Vasc Res 36:477–485.
   Google Scholar
• Maurer P. Hohenester E, Engel J. (1996). Extracel-lular calcium-binding proteins. Curr Opin Cell Biol 8:609–617.
   Google Scholar
• Miller JR, Hocking AM, Brown JD, Moon RT. (1999). Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways. Onco-gene 18:7860–7872.
   Google Scholar
• Moll T, Dejana E, Vestweber D. (1998). In vitro deg-radation of endothelial catenins by a neutrophil pro-tease. J Cell Biol 140:403–407.
   PubMedGoogle Scholar
• Muller WA, Randolph GJ. (1999). Migration of leu-kocytes across endothelium and beyond: molecules involved in the transmigration and fate of monocytes. J Leukoc Biol 66:698–704.
   PubMed Web of Science ®Google Scholar
• Orford K, Crockett C, Jensen JP, Weissman AM, By-ers SW. (1997). Serine phosphorylation-regulated ubiquitination and degradation of beta- catenin. J Biol Chem 272:24735–24738.
   PubMed Web of Science ®Google Scholar
• Panes J, Granger DN. (1998). Leukocyte-endothelial cell interactions: Molecular mechanisms and implica-tions in gastrointestinal disease. Gastroenterology 114:1066–1090.
   PubMed Web of Science ®Google Scholar
• Sandig M, Korvemaker ML, Ionescu CV, Negrou E, Rogers KA. (1999). Transendothelial migration of monocytes in rat aorta: Distribution of F-actin, al-pha-catenin, LFA-1, and PECAM-1. Biotech Histo-chem 74:276–293.
   PubMed Web of Science ®Google Scholar
• Sandig M, Negrou E, Rogers KA. (1997). Changes in the distribution of LFA-1, catenins, and F-actin dur-ing transendothelial migration of monocytes in cul-ture. J Cell Sci 110:2807–2818.
   PubMedGoogle Scholar
• Springer TA. (1995). Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigra-tion. Annu Rev Physiol 57:827–872.
   Google Scholar
• Steinberg MS, McNutt PM. (1999). Cadherins and their connections: adhesion junctions have broader functions. Curr Opin Cell Biol 11:554–560.
   PubMed Web of Science ®Google Scholar
• Su WH, Chen H, Huang J, Jen CJ. (2000). Endothe-lial [Ca(2+)](i) signaling during transmigration of polymorphonuclear leukocytes. Blood 96:3816–3822 .
   PubMed Web of Science ®Google Scholar
• Tkalcevic J, Novelli M, Phylactides M, Iredale JP, Se-gal, AW, Roes J. (2000). Impaired immunity and en-hanced resistance to endotoxin in the absence of neu-trophil elastase and cathepsin G. Immunity 12:201–210.
   PubMed Web of Science ®Google Scholar
• Vestweber D, Blanks JE. (1999). Mechanisms that regulate the function of the selectins and their li-gands. Physiol Rev 79:181–213.
   PubMed Web of Science ®Google Scholar
• Woodman RC, Reinhardt PH, Kanwar S, Johnston FL, Kubes P.(1993). Effectsofhuman neutrophilelas-tase (HNE) on neutrophil function in vitro and in inflamed microvessels. Blood 82:2188–2195.
   Google Scholar
• Yoshida N, Granger DN, Anderson DC, Rothlein R, Lane C, Kvietys PR. (1992). Anoxia/reoxygenation-induced neutrophil adherence to cultured endothelial cells. Am J Physiol 262:H1891–H1898.
   Google Scholar