The Rat Glomerular Filtration Barrier Does Not Show Negative Charge Selectivity

REFERENCES

• Baylis C, Fredericks M, Leypoldt J, Frigon R, Wilson C, Henderson L. (1988). The mechanisms of protein-uria in aging rats. Mech Ageing Dev 45:111–126.
   PubMed Web of Science ®Google Scholar
• Bertolatus JA, Hunsicker LG. (1985). Glomerular sieving of anionic and neutral bovine albumins in proteinuric rats. Kidney Int 28:467–476.
   Google Scholar
• Brenner BM, Hostetter TH, Humes HD. (1978). Glo-merular permselectivity: barrier function based on discrimination of molecular size and charge. Am J Physiol 234:F455–F460.
   Google Scholar
• Brunskill NJ, Cockcroft N, Nahorski S, Walls J. (1996). Albumin endocyotsis is regulated by het-erotrirneric GTP-binding protein Ceti_3 in opossum kidney cells. Am J Physiol 271:F356–F364.
   Google Scholar
• Carbajal ym, Schaeffer RC Jr. (1999). ADP ribosyla-tion of rho proteins reorganizes actomyosin filaments to cell-cell junctions and enhances endothelial barrier function. Am J Physiol 277:C955–C964.
   Google Scholar
• Chang RLS, Deen W1VI, Robertson CR, Brenner BM. (1975). Permselectivity of the glomerular capillary wall: III. Restricted transport of polyanions. Kidney Int 8:212–218.
   Google Scholar
• Chang RLS, Ueki IF, Troy JL, Deen WM, Robertson CR, Brenner BM. (1975). Permselectivity of the glo-merular capillary wall to macromolecules. II. Experi-mental studies in rats using neutral dextran. Bio-physical J 15:861–886.
   Google Scholar
• Comper WD, Glasgow EF. (1995). Charge selectivity in kidney ultrafiltration. Kidney Jut 47:1242–1251.
   Google Scholar
• Comper WD, Tay M, Wells X, Dawes J. (1994). Des-ulphation of dextran sulfate during kidney ultrafiltra-don. Biochem J 297:31–34.
   PubMedGoogle Scholar
• Dean W1VI, Satvat B, Jamieson ym. (1980). Theoretical model for glomerular filtration of charged solutes. Am J Physiol F126–F130.
   Google Scholar
• Fogh-Anderson N, Bjerrurn PJ, Siggaard-Anderson O. (1993). Ionic binding, net charge and donnan effect of human serum albumin as a function of pH. Clin Chem 39:48–52.
   Google Scholar
• Gandhi RR, Bell DR. (1992). Importance of charge on transvascular albumin transport in skin and skeletal muscle. Am J Physiol H999–H1008.
   Google Scholar
• Guasch A, Deen W1VI, Myers BD. (1993). Charge se-lectivity of the glomerular filtration bather in healthy and nephrotic humans. J Clin Invest 92:2274–2282.
   PubMed Web of Science ®Google Scholar
• Hermanson GT. (1996). Protein modification with activated dextrans. In: Bioconju gate Techniques. Academic Press, San Diego. 623–629.
   Google Scholar
• Kanwar YS, Farquhar MG. (1979). Presence of hepa-ran sulfate in the glomerular basement membrane. Proc Natl Acad Sci USA 76:1303–1307.
   PubMed Web of Science ®Google Scholar
• Kaysen GA, Myers BD, Couser WC, Rabkin R, Felts JM. (1986). Biology of disease: mechanisms and con-sequences of proteinuria. Lab Invest 54:479–498.
   PubMed Web of Science ®Google Scholar
• Maddox DA, Deen W1VI, Brenner BM. (1992). Glo-merular filtration. In: Handbook of Physiology, Sec-tion 8: Renal Physiology, Vol. 1. (EE Windhager, Ed.) Oxford, New York. 512–638.
   Google Scholar
• Ogston AG, Michel CC. (1978). General descriptions of passive transport of neutral solute and solvent through membranes. Prog Biophys Mol Biol 34:197–217.
   Google Scholar
• Oliver JD, Simons JL, Troy JL, Provoost AP, Brenner BM, Deen W1VI. (1994). Proteinuria and impaired glo-merular permselectivity in uninephrectomized fawn-hooded rats. Am J Physiol 267:F917–F925.
   Google Scholar
• Purtell JN, Pesce AJ, Clyne DH, Miller WC, Pollack VE. (1979). Isoelectric point of albumin: effect of renal handling of albumin. Kidney Int 16:366–376.
   PubMed Web of Science ®Google Scholar
• Peters T. (1985). Serum albumin. Adv Protein Chem 37:161–245.
   Google Scholar
• Rainer G, Van Liew JIB, Feld LG. (1979). Filtration and reabsorption of endogenous low molecular weight protein in the rat kidney. Kidney Jut 16:394–403.
   Google Scholar
• Renkin EM, Gilmore JP. (1973). Glomerular filtration. In: Handbook of Physiology, Section 8: Renal Physiology. (J Orloff, RW Berliner, Eds.) American Physiological Society, Washington. 145–160.
   Google Scholar
• Rennke HG, Patel Y, Vekatachalam MA. (1978). Glomerular filtration of proteins: clearance of anionic, neutral and cationic horseradish peroxidase in the rat. Kidney Int 13:324–328.
   PubMedGoogle Scholar
• Remuzzi A, Battaglia C, Rossi L, Zoja C, Remuzzi G. (1987). Glomerular size selectivity in nephrotic rats exposed to diets with different protein content. Am J Physiol 253:F318–F327.
   Google Scholar
• Rodewald R, Karnovsky MJ. (1974). Porous structure of glomerular slit diaphragm in the rat and mouse. J Cell Biol 60:423–435.
   PubMed Web of Science ®Google Scholar
• Schaeffer RC Jr, Renkiewicz RR, Chilton SM, Marsh D, Carlson RW. (1986). Preparation and high perfor-mance size exclusion chromatographic analysis of fluorescein isothiocyanate hydroxy ethyl starch: mac-romolecular probes of the blood lymph barrier. Mi-crovasc Res 32:230–246.
   Google Scholar
• Schaeffer RC Jr, Bitrick MS, Holberg WC III, Katz MA. (1992). Macromolecular transport across endo-thelial monolayers. Jut J Microcirc 11:181–201.
   Google Scholar
• Schaeffer RC Jr, Gong FC, Bitrick MS Jr. (1992). Restricted diffusion of macromolecules by endothelial monolayers and small pore filters. Am J Physiol 263:L27–L36.
   Google Scholar
• Tay M, Comper WD, Singh AK. (1991). Charge se-lectivity in kidney ultrafiltration in association with glomerular uptake of transport probes. Am J Physiol 260:F549–F554.
   Google Scholar
• Yurchenco PD, Schittny JC. (1990). Molecular archi-tecture of basement membranes. FASER J 4:1577–1590.
   PubMed Web of Science ®Google Scholar