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Original Articles

Ordinary Differential Equation PK/PD Models Using the SAS Macro NLINMIX

, , , &
Pages 483-503 | Received 01 Feb 2003, Accepted 01 Jul 2003, Published online: 02 Feb 2007

References

  • Beal , S. L. and Sheiner , L. B. 1992 . NONMEM User's Guides San Francisco : NONMEM Project Group, University of California .
  • Bergman , R. N. and Bowden , C. R. 1981 . “ The minimal model approach to quantification of factors controlling glucose disposal in man ” . In Carbohydrate Metabolism Edited by: Cobelli , C. and Bergman , R. N. 269 – 296 . Wiley
  • Davidian , M. and Giltinan , D. M. 1995 . Nonlinear Models for Repeated Measurement Data London : Chapman & Hall .
  • Galecki , A. T. 1998 . NLMEM: A new SAS/IML macro for hierarchical models . Comput. Methods Progra. Biomed. , 55 : 207 – 216 . [CSA]
  • Lindstrom , M. J. and Bates , D. M. 1990 . Nonlinear mixed effects models for repeated measures data . Biometrics , 46 : 673 – 687 . [PUBMED] [INFOTRIEVE]
  • Pinheiro , J. C. and Bates , D. M. 1995 . Approximations to the log-likelihood function in the nonlinear mixed-effects model . J. Computat. Graph. Statist. , 4 : 12 – 35 .
  • Pinheiro , J. C. and Bates , D. M. 2000 . Mixed-Effects Models in S and S-PLUS New York : Springer-Verlag .
  • SAS Institute Inc. (1999a). SAS/IML User's Guide, Version 7. Cary, NC: SAS Institute Inc
  • SAS Institute Inc. (1999b). SAS/STAT User's Guide, Version 8. Cary, NC: SAS Institute Inc
  • Vonesh , E. F. and Chinchilli , V. M. 1997 . Linear and Nonlinear Models for the Analysis of Repeated Measurements New York : Marcel Decker, Inc .
  • Wastney , M. E. , Patterson , B. H. , Linares , O. A. , Greif , P. C. and Boston , R. C. 1999 . Investigating Biological Systems Using Modelling San Diego : Academic Press .
  • Wolfinger , R. D. 1993 . Laplace's approximation for nonlinear mixed effects models . Biometrika , 80 : 791 – 795 .
  • Wolfinger , R. D. and Lin , X. 1997 . Two Taylor-series approximation methods for nonlinear mixed models . Computat. Statist. Data Analy. , 25 : 465 – 490 . [CROSSREF]

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