CARDIOVASCULAR REGULATION IN TGR(mREN2)27 RATS: 24h VARIATION IN PLASMA CATECHOLAMINES, ANGIOTENSIN PEPTIDES, AND TELEMETRIC HEART RATE VARIABILITY

REFERENCES

• Mullins J. J., Peters J., Ganten D. Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene. Nature 1990; 344: 541–544
   PubMed Web of Science ®Google Scholar
• Véniant M., Withworth C. E., Ménard J., Sharp M. G., Gonzales M. F., Bruneval P., Mullins J. J. Developmental studies demonstrate age-dependent elevation of renin activity in TGR(mRen2)27 rats. Am. J. Hypertens 1995; 8: 1167–1176
   PubMed Web of Science ®Google Scholar
• Bachmann S., Peters J., Engler E., Ganten D., Mullins J. Transgenic rats carrying the mouse renin gene—morphological characterization of a low-renin hypertension model. Kidney Int. 1992; 41: 24–36
   PubMed Web of Science ®Google Scholar
• Lemmer B., Mattes A., Böhm M., Ganten D. Circadian blood pressure variation in transgenic hypertensive rats. Hypertension 1993; 22: 97–101
   PubMed Web of Science ®Google Scholar
• Lemmer B., Witte K., Makabe T., Ganten D., Mattes A. Effects of enalaprilat on circadian profiles in blood pressure and heart rate of spontaneously and transgenic hypertensive rats. J. Cardiovasc. Pharmacol. 1994; 23: 11–314
   Google Scholar
• Schnecko A., Witte K., Lemmer B. Effect of the angiotensin II receptor antagonist losartan on 24-hour blood pressure profiles of primary and secondary hypertensive rats. J. Cardiovasc. Pharmacol. 1995; 26: 214–221
   PubMed Web of Science ®Google Scholar
• DeQuattro V., Campese V., Miura Y., Meijer D. J. Increased plasma catecholamines in high renin hypertension. Am. J. Cardiol 1976; 38: 801–804
   PubMed Web of Science ®Google Scholar
• Starke K. Beziehungen zwischen dem Renin-Angiotensin-System und dem vegetativen Nervensystem. Klin. Wschr. 1972; 50: 1069–1081
   PubMedGoogle Scholar
• Boadle C. M., Hughes J., Roth R. H. Angiotensin accelerates catecholamine biosynthesis in sympathetically innervated tissues. Nature 1969; 222: 987–988
   PubMed Web of Science ®Google Scholar
• Khairallah P. A. Action of angiotensin on adrenergic nerve endings: inhibition of norephinephrine uptake. Federation Proc. 1972; 31: 1351–1357
   PubMedGoogle Scholar
• Ferrario C. M. Neurogenic actions of angiotensin II. Hypertension 1983; 5: 73–79
   PubMedGoogle Scholar
• Vatta M. S., Bianciotti L. G., Locatelli A. S., Papouchado M. L., Fernandez B. E. Monophasic and biphasic effects of angiotensin II and III on norepinephrine uptake and release in rat adrenal medulla. Can. J. Physiol. Pharmacol 1992; 70: 821–825
   PubMed Web of Science ®Google Scholar
• National Institutes of Health, Guide for the Care and Use of Laboratory Animals, Available on line at http://www.nap.edu/readingrom/books/labrats
   Google Scholar
• Pleuler J. D., Johnson G. A. Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine. Life Sci. 1977; 21: 625–636
   PubMedGoogle Scholar
• Lomb N. R. Least-squares frequency analysis of unequally spaced data. Astrophys. Space Sci. 1976; 39: 447–462
   Web of Science ®Google Scholar
• Janssen B. J.A., Oosting J., Slaaf D. W., Persson P. B., Struijker-Boudier H. A. Hemodynamic basis of oscillations in systemic arterial pressure in conscious rats. Am. J. Physiol. 1995; 269: H62–H71
   PubMed Web of Science ®Google Scholar
• Presciuttini B., Duprez D., De Buyzere M., Clement D. L. How to study sympatho- vagal balance in arterial hypertension and the effect of antihypertensive drugs. Acta Cardiol. 1998; 53: 143–152
   PubMedGoogle Scholar
• Mattes A., Witte K., Hohman W., Lemmer B. PHARMFIT—a nonlinear fitting program for pharmacology. Chronobiol. Int. 1991; 8: 460–476
   PubMed Web of Science ®Google Scholar
• Witte K., Zuther P., Lemmer B. Analysis of telemetric time series data for periodic components using DQ-Fit. Chronobiol. Int. 1997; 14: 561–574
   PubMed Web of Science ®Google Scholar
• Ackermann H. BIAS: Biometrische Analyse von Stichproben. Epsilon-Verlag, Hochheim-DarmstadtGermany 1997
   Google Scholar
• McCarty R., Kvetnansky R., Kopin I. J. Plasma catecholamines in rats: daily variations in basal levels and increments in response to stress. Physiol. Behav. 1981; 26: 27–31
   PubMed Web of Science ®Google Scholar
• de Boer S. F., van der Gugten J. Daily variations in plasma noradrenaline, adrenaline and corticosterone concentrations in rats. Physiol. Behav. 1987; 40: 323–328
   PubMed Web of Science ®Google Scholar
• Goldstein D. S., McCarty R., Polinsky R. J., Kopin I. J. Relationship between plasma norephinephrine and sympathetic neural activity. Hypertension 1983; 5: 552–559
   PubMed Web of Science ®Google Scholar
• Lemmer B., Saller R. Influence of light and darkness on the turnover of noradrenaline in the rat heart. Naunyn-Schmiedebergs Arch. Pharmacol. 1974; 282: 75–84
   PubMedGoogle Scholar
• Globig S., Witte K., Lemmer B. Urinary excretion of nitric oxide, cyclic GMP, and catecholamines during rest and activity period in transgenic hypertensive rats. Chronobiol. Int. 1999; 16(3)305–314
   PubMed Web of Science ®Google Scholar
• Lemmer B., Witte K., Schänzer A., Findeisen A. Circadian rhythms in the reninangiotensin- system may contribute to the inverse blood pressure rhythm in hypertensive TGR(mREN-2)27 rats. Chronobiol. Int. 2000; 17: 645–658
   PubMed Web of Science ®Google Scholar
• Witte K., Huser L., Knotter B., Heckmann M., Schiffer S., Lemmer B. Normalisation of blood pressure in hypertensive TGR(mREN2)27 rats by amlodipine versus enalapril: effects on cardiac hypertrophy and signal transduction pathways. Naunyn- Schmiedebergs Arch. Pharmacol. 2001; 363: 101–109
   PubMedGoogle Scholar
• Böhm M., Moll M., Schmid B., Paul M., Ganten D., Castellano M., Erdmann E. β-Adrenergic neuroeffector mechanisms in cardiac hypertrophy of renin transgenic rat. Hypertension 1994; 24: 653–662
   PubMedGoogle Scholar
• Witte K., Schnecko A., Perbandt K., Höfer S., Lemmer B. Signal transduction in cardiac and vascular tissue form normotensive and transgenic hypertensive TGR(mREN2)27 rats. Eur. J. Pharmacol. 1998; 341: 337–341
   PubMedGoogle Scholar
• Campbell D., Rong P., Kladis A., Rees B., Ganten D., Skinner S. L. Angiotensin and bradykinin peptides in the TGR(mREN-2)27 rat. Hypertension 1995; 25: 1014–1020
   PubMed Web of Science ®Google Scholar