Effects of Diazepam and Its Metabolites on Nocturnal Melatonin Secretion in the Rat Pineal and Harderian Glands. A Comparative In Vivo and In Vitro Study

References

• Anis Y., Nir I., Schmidt U., Zisapel N. Modification by oxazepam of the diurnal variations in brain 125I-melatonin binding sites in sham-operated and pinealectomized rats. J. Neural Transm. 1992; 89: 155–166
   Web of Science ®Google Scholar
• Atsmon J., Oaknin S., Laudon M., Laschiner S., Gavish M., Dagan Y., Zisapel N. Reciprocal effects of chronic diazepam and melatonin on brain melatonin and benzodiazepine binding sites. J. Pineal Res. 1996; 20: 65–71
   PubMed Web of Science ®Google Scholar
• Benstaali C., Mailloux A., Bogdan A., Auzeby A., Touitou Y. Circadian rhythms of body temperature and motor activity in rodents their relationships with the light–dark cycle. Life Sci. 2001; 68: 2645–2656
   PubMed Web of Science ®Google Scholar
• Brammer G. L., Yuwiler A., Wetterberg L. N-acetyltransferase activity of the rat Harderian gland. Biochem. Biophys. Acta 1978; 526: 93–99
   PubMed Web of Science ®Google Scholar
• Brown G. M., Seggie J., Grota J. L. Serum melatonin response to melatonin administration in the Syrian hamster. Neuroendocrinology 1985; 41: 31–35
   PubMed Web of Science ®Google Scholar
• Champney T. H., Holtorf A. P., Steger R. J., Reiter R. J. Concurrent determination of enzymatic activities and substrate concentrations in the melatonin synthetic pathway within the same pineal gland. J. Neurosci. Res. 1984; 11: 59–65
   PubMed Web of Science ®Google Scholar
• Djeridane Y. The Harderian gland and its excretory duct in the wistar rat. A histological and ultrastructural study. J. Anat. 1994; 184: 553–566
   PubMed Web of Science ®Google Scholar
• Djeridane Y. Histological and ultrastructural features of the rodent Harderian glands. Microsc. Res. Tech. 1996; 34: 28–38
   PubMed Web of Science ®Google Scholar
• Djeridane Y., Touitou Y. Chronic diazepam administration affects differently melatonin synthesis in rat pineal and Harderian glands. Psychopharmacology 2001a; 154: 403–407
   PubMed Web of Science ®Google Scholar
• Djeridane Y., Touitou Y. Melatonin synthesis in the rat harderian gland: Age- and time-related effects. Exp. Eye Res. 2001b; 72: 487–492
   PubMed Web of Science ®Google Scholar
• Djeridane Y., Vivien-Roels B., Simonneaux V., Miguez J. M., Pévet P. Evidence for melatonin synthesis in rodent Harderian gland: a dynamic in vitro study. J. Pineal Res. 1998; 25: 54–64
   PubMed Web of Science ®Google Scholar
• Djeridane Y., Klosen P., Vivien-Roels B., Simonneaux V., Pévet P. Immunohistochemical evidence for the presence of tryptophan hydroxylase and serotonin in rodent Harderian gland. Cell. Tissue Res. 1999; 296: 517–523
   PubMed Web of Science ®Google Scholar
• Donalson E., Kennaway D. J. Effects of temazepam on sleep, performance, and rhythmic 6-sulphatoxymelatonin and cortisol excretion after transmeridien travel. Aviat. Space Environ. Med. 1991; 62: 654–660
   PubMedGoogle Scholar
• Fraser S., Cowen P., Franklin M., Franey C., Arendt J. Direct radioimmunoassay for melatonin in plasma. Clin. Chem. 1983; 29: 396–397
   PubMed Web of Science ®Google Scholar
• Lewis A. J., Kerenyi N. A., Feuer G. Neuropharmacology of pineal secretions. Drug Metab. Drug Interact. 1990; 8: 247–312
   PubMedGoogle Scholar
• Lowenstein P. R., Gonzalez Solveyra C., Keller Sarmiento M. I., Cardinali D. P. Benzodiazepines decrease norepinephrine release from rat pineal nerves by acting on peripheral type binding sites. Acta Physiol. Pharmacol. Latinoam. 1985; 35: 441–449
   PubMedGoogle Scholar
• Mailliet F., Galloux P., Poisson D. Comparative effects of melatonin, zolpidem and diazepam on sleep, body temperature, blood pressure and heart rate measured by radiotelemetry in wistar rats. Psychopharmacology 2001; 156: 417–426
   PubMed Web of Science ®Google Scholar
• Matthew E., Parfitt A. G., Sugden D., Engelhardt D. L., Zimmerman E. A., Klein D. C. Benzodiazepines: rat pinealocyte binding sites and augmentation of norepinephrine-stimulated N-acetyltransferase activity. J. Pharmacol. Exp. Ther. 1984; 228: 434–438
   PubMed Web of Science ®Google Scholar
• Monteleone P., Forziati D., Orazzo C., Maj M. Preliminary observations on the suppression of nocturnal plasma melatonin levels by short-term administration of diazepam in humans. J. Pineal Res. 1989; 6: 253–258
   PubMed Web of Science ®Google Scholar
• Morton D. J. Effect of anticonvulsant drugs in vivo on rat pineal N-acetyltransferase (EC 2.3.1.5) and hydroxyindole-O-methyltransferase (EC 2.1.1.4). J. Pineal Res. 1986; 3: 181–186
   PubMed Web of Science ®Google Scholar
• Norman T. R., Piccolo J., Voudouris N., Burrows G. D. The effect of single oral doses of zopiclone on nocturnal melatonin secretion in healthy male volunteers. Prog. Neuropsychopharmacol. Biol. Psychiatr. 2001; 25: 825–833
   PubMed Web of Science ®Google Scholar
• Oxenkrug G. F., Harris P. Q. Benzodiazepines attenuate clorgyline-induced stimulation of melatonin synthesis. Pharmacol. Res. Commun. 1988; 20: 143–144
   Google Scholar
• Oxenkrug G. F., Requintina P. Central but not peripheral benzodiazepine agonists attenuate clorgyline effect on melatonin synthesis. Biol. Psychiatr. 1990; 27: 68
   Google Scholar
• Philo R., Berkowitz A. S. Subcutaneous diazepam implants counteract short-photoperiod induction of testicular regression in Mesocricetus auratus, the golden hamster. Anat. Rec. 1984; 208: 139
   Google Scholar
• Reiter R. J. Pineal melatonin: cell biology of its synthesis and of its physiological interactions. Endocr. Rev. 1991; 12: 151–180
   PubMed Web of Science ®Google Scholar
• Rickles K., DeMartinis N., Aufdembrinke B. A double-blind, placebo-controlled trial of abecarnil and diazepam in the treatment of patients with generalized anxiety disorder. J. Clin. Psychopharmacol. 2000; 20: 12–18
   PubMed Web of Science ®Google Scholar
• Stone B. M., Turner C., Mills S. L., Nicholson A. N. Hypnotic activity of melatonin. Sleep 2000; 23: 663–669
   PubMed Web of Science ®Google Scholar
• Wakabayashi H., Shimada K., Aizawa Y., Satoh T. Effect of psychotropic drugs on the contents of melatonin, serotonin and N-acetylserotonin in rat pineal gland. Jpn J. Pharmacol. 1989; 49: 225–234
   PubMedGoogle Scholar
• Wakabayashi H., Shimada K., Satoh T. Effects of adrenergic blockers or bicuculline on diazepam induced changes in rat pineal melatonin synthesis in vivo and in vitro. Chem. Pharm. Bull. 1991a; 39: 2677–2680
   PubMed Web of Science ®Google Scholar
• Wakabayashi H., Shimada K., Satoh T. Effects of diazepam administration on melatonin synthesis in the rat pineal gland in vivo. Chem. Pharm. Bull. 1991b; 39: 2674–2676
   PubMed Web of Science ®Google Scholar
• Winters W. D., Yuwiler A., Oxenkrug G. F. The effects of benzodiazepines on basal and isoproterenol-stimulated N-acetyltransferase activity by the rat pineal gland, in vivo and in vitro. J. Pineal Res. 1991; 10: 151–158
   PubMed Web of Science ®Google Scholar
• Zatz M., Brownstein M. J. Central depressants rapidly reduce nocturnal serotonin N-acetyltransferase activity in the rat pineal gland. Brain Res. 1979; 160: 381–385
   PubMed Web of Science ®Google Scholar
• Zhao Z. Y., Touitou Y. Response of rat pineal melatonin to calcium, magnesium, and lithium is circadian stage dependent. J. Pineal Res. 1993; 14: 73–77
   PubMed Web of Science ®Google Scholar