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Research Article

Seizures Reported in Association with Use of Dietary Supplements

, M.D., , Pharm.D. & , M.D.
Pages 23-30 | Published online: 07 Oct 2008

References

  • Palmer M E, Haller C, McKinney P E, Klein-Schwarz W, Tsehirgi A, Smolinske S, Woolf A, Sprague B M, Ko R, Everson G, Nelson L, Dodd-Boleva T, Bartlett W, Lantzberg B. Adverse events associated with dietary supplements: an observational study. Lancet 2003; 361:101–106.
  • Haller C A, Benowitz N L. Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids. N Engl J Med 2000; 343:1833–1838.
  • Humberston C L, Akhtar J, Krenzelok E P. Acute hepatitis induced by kava kava. J Toxicol Clin Toxicol 2003; 41(2):109–113.
  • Fugh-Berman A. Herb-drug interactions. Lancet 2000; 355:134–138.
  • Johne A, Brockmoller J, Bauer S, Maurer A, Langheinrich M, Roots I. Pharmacokinetic interaction of digoxin with an herbal extract from St. John's wort (Hypericum perforatum). Clin Pharmacol Ther 1999; 66:338045.
  • Piscitelli S C, Burstein A H, Chaitt D, Alfaro R M, Falloon J. Indinavir concentrations and St. John's wort. Lancet 2000; 355:547–548.
  • Aggarwal A, Ades P A. Interactions of herbal remedies with prescription cardiovascular medication. Coron Artery Dis 2001; 12:581–584.
  • Almeida J C, Grimsley E W. Coma from the health food store: interaction between kava and alprazolam. Ann Intern Med 1996; 125(11):940–941.
  • Cupp M J. Herbal remedies: adverse effects and drug interactions. Am Fam Phys 1999; 59(5):1239–1245.
  • DiPaola R S, Zhang H, Lambert G H, Meeker R, Licitra E, Rafi M M, Zhu B T, Spaulding H, Goodin S, Toledano M B, Hait W N, Gallo M A. Clinical and biologic activity of an estrogenic herbal combination (PC-SPES) in prostate cancer. N Engl J Med 1998 Sep 17; 339(12):785–791.
  • White J. Editorial: PC-SPES—a lesson for future dietary supplement research. J Natl Cancer Inst 2002; 94:1261–1263.
  • Slifman N R, Obermeyer W R, Aloi B K, Musser S M, Correll W A, Cichowicz S M, Betz J M, Love L A. Contamination of botanical dietary supplements by Digitalis lanata. N Engl J Med 1998; 339:806–811.
  • Williamson B L, Tomlinson A J, Mishra P K, Gleich G J, Naylor S. Structural characterization of contaminants found in commercial preparations of melatonin: similarities to case-related compounds from L-tryptophan associated with eosinophilia-myalgia syndrome. Chem Res Toxicol 1998; 11:234–240.
  • Gurley B J, Gardner S F, Hubbard M A. Content versus label claims in ephedra-containing dietary supplements. Am J Health Syst-Pharm 2000; 57:963–969.
  • Harkey M R, Henderson G L, Gershwin M E, Stern J S, Hackman R M. Variability in commercial ginseng products: an analysis of 25 preparations. Am J Clin Nutr 2001; 73:1101–1106.
  • Green G A, Catlin D H, Starcevic B. Analysis of over-the-counter dietary supplements. Clin J Sport Med 2001; 11:254–259.
  • Russell A S, Aghazadeh-Habashi A, Jamali F. Active ingredient consistency of commercially available glucosamine sulfate products. J Rheumatol 2002; 29:2407–2409.
  • Shekelle P G, Hardy M L, Morton S C, Maglione M, Mojica W A, Suttorp M J, Rhodes S L, Jungurg L, Gagné J. Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance. JAMA 2003; 289:1537–1545.
  • Samenuk D, Link M S, Homoud M K, Contreras R, Theoharides T C, Wang P J, Estes N A III, Theohardes T C. Adverse cardiovascular events temporally associated with Ma Huang, an herbal source of ephedrine. Mayo Clin Proc 2002; 77:12–16.
  • Favreau J T, Ryu M L, Braunstein G, Orshansky G, Park S, Coody G L, Love L A, Fong F L. Severe hepatotoxicity associated with the dietary supplement lipokinetix. Ann Intern Med 2002; 136:590–595.
  • Sheikh N M, Philen R M, Love L A. Chaparral-associated hepatotoxicity. Arch Intern Med 1997 Apr 28; 157(8):913–919.
  • From the Centers for Disease Control and Prevention. Hepatic toxicity possibly associated with kava-containing products—United States,Germany, and Switzerland, 1999–2002. JAMA 2003 Jan 1; 289(1):36–37.
  • From the Centers for Disease Control and Prevention. Adverse events associated with ingestion of gamma-butyrolactone—Minnesota, New Mexico, and Texas, 1998–1999. JAMA 1999 Mar 17; 281(11):979–980.
  • Kockler D R, McCarthy M W, Lawson C L. Seizure activity and unresponsiveness after Hydroxycut Ingestion. Pharmacotherapy. 2001; 21(5):647–651.
  • Spinella M. Herbal medicines and epilepsy: the potential for benefit and adverse effects. Epilepsy Behav 2001; 2:524–532.
  • Blanc S, Leuenberger P, Berger J P, Brooke E M, Schelling J L. Judgments of trained observers on adverse drug reactions. Clin Pharmacol Ther 1979; 25(5):493–498.
  • Bye C, Dewsbury D, Peck AW. Effects on the human central nervous system of two isomers of ephedrine and triprolidine, and their interaction. Br J Clin Pharmacol 1974; 1:71–78.
  • Anderson K G, Winger G, Woods J, Woolverton W L. Reinforcing and discriminative-stimulus effects of ephedrine isomers in rhesus monkeys. Drug Alcohol Depend 2001; 65:45–53.
  • Lanciault G, Wolf H H. Some neuropharmacological properties of the ephedrine isomers. J Pharm Sci 1965; 54(6):841–844.
  • Wolf H H, Rollins D E, Rowland C R, Reigle T G. The importance of endogenous catecholamines in the activity of some CNS stimulants. Int J Neuropharmacol 1969; 8:319–328.
  • Kalix P. The pharmacology of psychoactive alkaloids from Ephedra and Catha. J Ethnopharmacol 1991; 32:201–208.
  • Benowitz N L. Clinical pharamcology of caffeine. Annu Rev Med 1990; 41:277–288.
  • Shum S, Seale C, Hathaway D, Chucovich V, Beard D. Acute caffeine ingestion fatalities: management issues. Vet Hum Toxicol 1997; 39(4):228–230.
  • Banner W, Czajka P A. Acute caffeine overdose in the neonate. Am J Dis Child 1980; 134(5):495–498.
  • Marangos P J, Martino A M, Paul S M, Skolnick P. The benzodiazepines and inosine antagonize caffeine-induced seizures. Psychopharmacology (Berl) 1981; 72(3):269–273.
  • Walker J S. Phenylpropanolamine potentiates caffeine neurotoxicity in rats. J Pharm Sci 1980; 78(12):986–989.
  • New drug status of OTC combination drug products containing caffeine, phenylpropanolamine, and ephedrine. Fed. Reg. 1982; 47:35344–35346.
  • Lake C R, Quirk R S. CNS stimulants and the look-alike drugs. Psych Clin N Am 1984; 7(4):689–701.
  • Mueller S M, Solow E B. Seizures associated with a new combination "pick-me-up" pill. Ann Neurol 1982; 11:322
  • D'Nicuola J D, Jones R, Levine B, Smith M L. Evaluation of six commercial amphetamine and methamphetamine immunoassays for cross-reactivity to phenylpropanolamine and ephedrine in urine. J Anal Toxicol 1992; 16:211–21341.
  • Stout P R, Klette K L, Wiegand R. Comparison and evaluation of DRI Methamphetamine, DRI Ecstasy, Abuscreen ONLINE Amphetamine and a modified Abuscreen ONLINE amphetamine screening immunoassays for the detection of amphetamine (AMP), methamphetamine (MTH), 3,4-Methylenediosxyamphetamine (MDA), and 3,4-Methylenedioxymethamphetamine (MDMA) in human urine. J Anal Toxicol 2003; 27:1–5.
  • Miwa H, Iijima M, Tanaka S, Mizuno Y. Generalized convulsions after consuming a large amount of gingko nuts. Epilepsia 2001; 42:280–281.
  • Granger A S. Ginkgo biloba precipitating epileptic seizures. Age Ageing 2001; 134:344
  • Moses E L, Mallinger A G. St John's Wort: three cases of possible mania induction. J Clin Psychopharmacol 2000; 20:115–117.
  • Brown T M. Acute St. John's wort toxicity. Am J Emerg Med 2000; 18:231–232.
  • Wang Z, Gorski J C, Hamman M A, Huang S M, Lesko L J, Hall S D. The effects of St. John's wort (Hypericum perforatum) on human cytochrome P450 activity. Clin Pharmacol Ther 2001; 70:3126–3127.
  • http://www.hhs.gov/news/press/2003pres/20031230.html.

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