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Clinical Toxicology Volume 43, 2005 - Issue 3
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Article

Delayed Neurologic Sequelae Resulting from Epidemic Diethylene Glycol Poisoning

Dr. Sam Alfred Division of Clinical Toxicology, Department of Emergency Medicine, Westmead Hospital, Westmead, Australia; Division of Clinical Toxicology, Department of Emergency Medicine, Westmead Hospital, Westmead, NSW, 2145, Australia
, F.A.C.E.M. , M.B.B.S.,
Patrick Coleman Centre for Transplantation and Renal Research, Millenium Institute, Westmead, Australia
, F.R.C.A.P. , M.B. , M.R.C.P.I.,
David Harris Centre for Transplantation and Renal Research, Millenium Institute, Westmead, Australia
, F.R.A.C.P. , M.B.B.S.,
Tim Wigmore Department of Intensive Care Medicine, Westmead Hospital, Westmead, Australia
, F.R.C.A. , B.A. , M.A. , B.M. , B.Ch.,
Edward Stachowski Department of Intensive Care Medicine, Westmead Hospital, Westmead, Australia
, F.J.F.I.C.M. , M.B.B.S. , F.A.N.Z.C.A. &
Andis Graudins Clinical and Experimental Toxicology Unit, Department of Emergency Medicine, Prince of Wales Hospital, Prince of Wales Clinical School, University of New South Wales, Randwick, Australia
, F.A.C.E.M. F.A.C.M.T. , M.B.B.S. , Ph.D.
Pages 155-159 | Published online: 11 Aug 2009

References

  • Von Oettingen, W F, Jirouch, E A. Pharmacology of ethylene glycol and some of its derivatives. J Pharmacol Exp Ther 1931; 42:355.
  • Haag, H B, Ambrose, A M. Studies of the physiological effects of diethylene glycol. J Pharmacol Exp Ther 1937; 59:93.
  • Leech, P N. Elixir of sulphanilamide-massengill. JAMA 1937; 109(19):1531–1539.
  • Calvery, H O, Klumpp, T G. The toxicity for human beings of diethylene glycol with sulphanilamide. South Med J 1939; 32(11):1105–1109.
  • Lynch, K M. Diethylene glycol poisoning in the human. South Med J 1938; 31(2):134–137.
  • Bowie, M D. Diethlyene glycol poisoning in children. South Afr Med J 1972; 46:931–934.
  • Cantarell, M C, Fort, J, Camps, J, Sans, M, Piera, L. Acute intoxication due to topical application of diethylene glycol (letter). Ann Intern Med 1987; 106(3):478–479. [PUBMED], [INFOTRIEVE]
  • Pandya, S K. An unmitigated tragedy (letter). BMJ 1988; 297:117–119. [PUBMED], [INFOTRIEVE]
  • Okuonghae, H O, Ighogboja, I S, Lawson, J O, Nwana, J C. Diethylene glycol poisoning in Nigerian children. Ann Trop Paediatr 1992; 12:235–238. [PUBMED], [INFOTRIEVE]
  • Hanif, M, Mobarak, M R, Ronan, A, Rahman, D, Donovan, J J, Bennish, M L. Fatal renal failure caused by diethlyene glycol in paracetamol elixir: the bangladeshi epidemic. BMJ 1995; 311:88–91. [PUBMED], [INFOTRIEVE]
  • Junod, S W. Diethylene glycol deaths in Haiti. Public Health Rep 2000; 115:78–86. [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Scalzo, A J. Diethylene glycol toxicity revisited: the 1996 Haitian epidemic. Clin Toxicol 1996; 34(5):513–516.
  • Rollins, Y D, Filley, C M, McNutt, J T, Chahal, S, Kleinschmidt-DeMasters, B K. Fulminant ascending paralysis as a delayed sequelae of diethlylene glycol (sterno) ingestion. Neurology 2002; 59:1460–1463. [PUBMED], [INFOTRIEVE], [CSA]
  • Drut, R, Quijano, G, Jones, M C, Scanferla, P. Hallazgos patologicos en la intoxicacion por dietilenglicol. Medicina 1994; 54:1–5. [PUBMED], [INFOTRIEVE]
  • Durand, A, Auzepy, P, Herbet, J L, Trien, T C. A study of mortality and urinary excretion of oxalate in male rats following acute experimental intoxication with diethlyene glycol. Eur J Int Care Med 1976; 2:143–146. [CROSSREF]
  • Herbet, J L, Fabre, M, Auzepy, P, Paillas, J, Durand, A. Acute experimental poisoning by diethylene glycol: acid base balance and histological data in male rats. Toxicol Eur Res 1978; 1:289–294.
  • Morris, H J, Nelson, A A, Calvery, A O. Observations on the chronic toxicities of propylene glycol, ethylene glycol, diethlylene glycol, ethylene glycol mono-ethly-ether, and diethlylene glycol mono-ethyl-ether. J Pharmacol Exp Ther 1942; 74:266–273.
  • Brown, C LM. Constitution and toxicities of the glycols. Pharm J 1938; 140:48.
  • Wiley, F H, Hueper, W C, Bergen, D S, Blood, F R. The formation of oxalic acid from ethlylene glycol and related solvents. J Ind Hyg Toxicol 1938; 20:269–277.
  • Balaz, T, Jackson, B, Hite, M. Nephrotoxicities of ethlylene glycols, cephalosporins and diuretics. Monogr Appl Toxicol 1982; 1:487–497.
  • Wiener, H L. Ethlylene and Diethlyene Glycol Metabolism, Toxicity and Treatment. PhD dissertation. Columbu, OH: The Ohio State University, 1986.
  • Wiener, H L, Richardson, K E. Metabolism of diethlylene glycol in male rats. Biochem Pharmacol 1989; 38(3):539–541. [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
  • Borron, S W, Garnier, M D. Intravenous 4-methylpyrazole as an antidote for diethlylene glycol and triethylene glycol poisoning: a case report. Vet Hum Toxicol 1997; 39(1):26–28. [PUBMED], [INFOTRIEVE], [CSA]
  • Vassiliadis, J, Graudins, A, Dowsett, R P. Triethlylene glycol poisoning treated with intravenous ethanol infusion. J Toxicol Clin Toxicol 1999; 37(6):773–776. [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]

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