Advanced search
Publication Cover
Cancer Investigation Volume 20, 2002 - Issue 1
Submit an article Journal homepage
334
Views
72
CrossRef citations to date
0
Altmetric
Original

Incidence and Severity of Hand–Foot Syndrome in Colorectal Cancer Patients Treated with Capecitabine: A Single-Institution Experience

Samer Abushullaih Department of Gastrointestinal Medical Oncology and Digestive Diseases, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, U.S.A.
, M.D.,
Everardo D. Saad Department of Gastrointestinal Medical Oncology and Digestive Diseases, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, U.S.A.
, M.D.,
Mark Munsell Department of Biostatistics, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, U.S.A.
, M.Sc. &
Paulo M. Hoff Department of Gastrointestinal Medical Oncology and Digestive Diseases, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, U.S.A.
, M.D.
Pages 3-10 | Published online: 22 Apr 2002

REFERENCES

  • Burgdorf W.H.C., Gilmore W.A., Ganick R.G. Peculiar Acral Erythema Secondary to High-Dose Chemotherapy for Acute Myelogenous Leukemia. Ann. Intern. Med. 1982; 97: 61–62
  • Lokich J.J., Moore C. Chemotherapy-Associated Palmar–Plantar Erythrodysesthesia Syndrome. Ann. Intern. Med. 1984; 101: 798–800
  • Baack B.R., Burgdorf W.H.C. Chemotherapy-Induced Acral Erythema. J. Am. Acad. Dermatol. 1991; 24: 457–461
  • De Vries E.G., Greidanus J., Mulder N.H., , et al. A Phase I and Pharmacokinetic Study with 21-Day Continuous Infusion of Epirubicin. J. Clin. Oncol. 1987; 5: 1445–1451
  • Vokes E.E., Raschko J.W., Vogelzang N.J., , et al. Five-Day Infusion of Fluorodeoxyuridine with High-Dose Oral Leucovorin: a Phase I Study. Cancer Chemother. Pharmacol. 1991; 28: 69–73
  • Vukelja S.J., Baker W.J., Burris H.A. Pyridoxine Therapy for Palmar–Plantar Erythrodysesthesia Associated with Taxotere. J. Natl Cancer Inst. 1993; 85: 1432–1433
  • Hoff P.M., Valero V., Ibrahim N., , et al. Hand–Foot Syndrome Following Prolonged Infusion of High Doses of Vinorelbine. Cancer 1998; 82: 965–969
  • Dooley M., Goa K.L. Capecitabine. Drugs 1999; 58: 69–76
  • Xeloda® (Capecitabine) Prescribing Information. Roche Laboratories, Nutley, NJ 1998
  • Blum J.L., Jones S.E., Buzdar A.U., , et al. Multicenter Phase II Study of Capecitabine in Paclitaxel-Refractory Metastatic Breast Cancer. J. Clin. Oncol. 1999; 17: 485–493
  • Fleiss J.L. Statistical Methods for Rates and Proportions. 2nd Ed, John Wiley and Sons, New York 1981
  • 4th Ed., SAS Institute Inc., Cary, NC 1989; Vols. 1 and 2
  • Budman D.R., Meropol N.J., Reigner B., , et al. Preliminary Studies of a Novel Oral Fluoropyrimidine Carbamate: Capecitabine. J. Clin. Oncol. 1998; 16: 1795–1802
  • Mackean M., Planting A., Twelves C., , et al. Phase I and Pharmacologic Study of Intermittent Twice-Daily Oral Therapy with Capecitabine in Patients with Advanced and/or Metastatic Cancer. J. Clin. Oncol. 1998; 16: 2977–2985
  • Cassidy J., Dirix L., Bissett D., , et al. A Phase I Study of Capecitabine in Combination with Oral Leucovorin in Patients with Intractable Solid Tumors. Clin. Cancer Res. 1998; 4: 2755–2761
  • Findlay M., Van Cutsem E., Kocha W., , et al. A Randomized Phase II Study of Xeloda™ (Capecitabine) in Patients with Advanced Colorectal Cancer. Proc. Am. Soc. Clin. Oncol. 1997; 16: 227a
  • Twelves C., Harper P., Van Cutsem E., , et al. A Phase III Trial (SO14796) of Xeloda™ (Capecitabine) in Previously Untreated Advanced/Metastatic Colorectal Cancer. Proc. Am. Soc. Clin. Oncol. 1999; 18: 263a
  • Cox J.V., Pazdur R., Thibault A., , et al. A Phase III Trial of Xeloda™ (Capecitabine) in Previously Untreated Advanced/Metastatic Colorectal Cancer. Proc. Am. Soc. Clin. Oncol. 1999; 18: 265a
  • Toxicity of Fluorouracil in Patients with Advanced Colorectal Cancer: Effect of Administration Schedule and Prognostic Factors. J. Clin. Oncol. 1998; 16: 3537–3541
  • Vogelzang N.J., Ratain M.J. Cancer Chemotherapy and Skin Changes. Ann. Intern. Med. 1985; 103: 303–304
  • Jones A.P., Crawford S.M. Anthracycline-Induced Toxicity Affecting Palmar and Plantar Skin. Br. J. Cancer 1989; 59: 814
  • Peters W.G., Willemze R. Palmar–Plantar Skin Changes and Cytarabine. Ann. Intern. Med. 1985; 103: 805
  • Gordon K.B., Tajuddin A., Guitart J., , et al. Hand–Foot Syndrome Associated with Liposome-Encapsulated Doxorubicin Therapy. Cancer 1995; 75: 2169–2173
  • Diasio R.B. The Role of Dihydropyrimidine Dehydrogenase (DPD) Modulation in 5-FU Pharmacology. Oncology (Huntingt) 1998; 12(Suppl 7)23–27
  • Hoff P.M., Pazdur R., Benner S.E., Canetta R. UFT and Leucovorin: A Review of Its Clinical Development and Therapeutic Potential in the Oral Treatment of Cancer. Anticancer Drugs 1998; 9: 479–490
  • Vukelja S.J., Lombardo F.A., James W.D., Weiss R.B. Pyridoxine for the Palmar–Plantar Erythrodysesthesia Syndrome. Ann. Intern. Med. 1989; 111: 688–689
  • Fabian C.J., Molina R., Slavik M., , et al. Pyridoxine Therapy for Palmar–Plantar Erythrodysesthesia Associated with Continuous 5-Fluorouracil Infusion. Invest. New Drugs 1990; 8: 57–63
  • Gyorgy P., Eckardt R. Vitamin B6 and Skin Lesions in Rats. Nature 1939; 144: 512
  • Beveridge R.A., Kales A.N., Binder R.A., , et al. Pyridoxine (B6) and Amelioration of Hand/Foot Syndrome. Proc. Am. Soc. Clin. Oncol. 1990; 9: 102a
  • Vail D.M., Chun R., Thamm D.H., , et al. Efficacy of Pyridoxine to Ameliorate the Cutaneous Toxicity Associated with Doxorubicin Containing Pegylated (Stealth) Liposomes: A Randomized, Double-Blind Clinical Trial Using a Canine Model. Clin. Cancer Res. 1998; 4: 1567–1571

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.