Can an Herbal Agent Replace Estrogen for Hot Flashes?

References

• Rossouw J. E., Anderson G. L., Prentice R. L., LaCroix A. Z., Kooperberg C., Stefanick M. L., Jackson R. D., Beresford S. A., Howard B. V., Johnson K. C., Kotchen J. M., Ockene J. Writing group for the Women's Health Initiative investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA 2002 Jul 17; 288(3)321–333
   PubMed Web of Science ®Google Scholar
• Hays J., Ockene J. K., Brunner R. L., Kotchen J. M., Manson J. E., Patterson R. E., Aragaki A. K., Shumaker S. A., Brzyski R. G., LaCroix A. Z., Granek I. A., Valanis B. G. Effects of estrogen plus progestin on health-related quality of life. N. Engl. J. Med. 2003 Mar 17; 348: 1839–1854, [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Goldberg R. M., Loprinzi C. L., O'Fallon J. R., Veeder M. H., Miser A. W., Mailliard J. A., Michalak J. C., Dose A. M., Rowland K. M., Jr, Burnham N. L. Transdermal clonidine for ameliorating tamoxifen-induced hot flashes. J. Clin. Oncol. 1994; 12: 155–158, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Loprinzi C. L., Michalak J. C., Quella S. K., O'Fallon J. R., Hatfield A. K., Nelimark R. A., Dose A. M., Fischer T., Johnson C., Klatt N. E., Bate W. W., Rospond R. M., Oesterling J. E. Megestrol acetate for the prevention of hot flashes. N. Engl. J. Med. 1994; 331: 347–352, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar
• Loprinzi C. L., Pisansky T. M., Fonseca R., Sloan J. A., Zahasky K. M., Quella S. K., Novotny P. J., Rummans T. A., Dumesic D. A., Perez E. A. Pilot evaluation of venlafaxine hydrochloride for the therapy of hot flashes in cancer survivors. J. Clin. Oncol. 1998; 16: 2377–2381, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Loprinzi C. L., Kugler J. W., Sloan J. A., Mailliard J. A., LaVasseur B. I., Barton D. L., Novotny P. J., Dakhil S. R., Rodger K., Rummans T. A., Christensen B. J. Venlafaxine in management of hot flashes in survivors of breast cancer: a randomised controlled trial. Lancet 2000; 356: 2059–2063, [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Loprinzi C. L., Sloan J. A., Perez E. A., Quella S. K., Stella P. J., Mailliard J. A., Halyard M. Y., Pruthi S., Novotny P. J., Rummans T. A. Phase III evaluation of fluoxetine for treatment of hot flashes. J. Clin. Oncol. 2002; 20: 1578–1583, [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Stearns V., Isaacs C., Rowland J., Crawford J., Ellis M. J., Kramer R., Lawrence W., Hanfelt J. J., Hayes D. F. A pilot trial assessing the efficacy of paroxetine hydrochloride (Paxil) in controlling hot flashes in breast cancer survivors. Ann. Oncol. 2000; 11: 17–22, [PUBMED], [INFOTRIEVE], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Barton D. L., Loprinzi C. L., Quella S. K., Sloan J. A., Veeder M. H., Egner J. R., Fidler P., Stella P. J., Swan D. K., Vaught N. L., Novotny P. Prospective evaluation of vitamin E for hot flashes in breast cancer survivors. J. Clin. Oncol. 1998; 16: 495–500, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Quella S. K., Loprinzi C. L., Barton D. L., Knost J. A., Sloan J. A., LaVasseur B. I., Swan D., Krupp K. R., Miller K. D., Novotny P. J. Evaluation of soy phytoestrogens for the treatment of hot flashes in breast cancer survivors: a North Central Cancer Treatment Group Trial. J. Clin. Oncol. 2000; 18: 1068–1074, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Wade C., Kronenberg F., Kelly A., Murphy P. A. Hormone-modulating herbs: implications for women's health. J. Am. Med. Women's Assoc. 1999; 54: 181–183
   PubMedGoogle Scholar
• Liske E. Therapeutic efficacy and safety of Cimicifuga racemosa for gynecologic disorders. Adv. Ther. 1998; 15: 45–53, [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Pepping J. Black cohosh: Cimicifuga racemosa. Am. J. Health-Syst. Pharm. 1999; 56: 1400–1402, [CSA]
   PubMed Web of Science ®Google Scholar
• Lieberman S. A review of the effectiveness of Cimicifuga racemosa (black cohosh) for the symptoms of menopause. J. Women's Health 1998; 7: 525–529
   PubMed Web of Science ®Google Scholar
• Pockaj B. A., Loprinzi C. L., Sloan J. A., Novotny P. J., Barton D. L., Hagenmaier A., Zhang H., Lambert G. H., Reeser K. A., Wisbey J. A. Pilot evaluation of black cohosh for the treatment of hot flashes in women. Cancer Investig., in press
   PubMed Web of Science ®Google Scholar
• Jacobson J. S., Troxel A. B., Evans J., Klaus L., Vahdat L., Kinne D., Lo K. M., Moore A., Rosenman P. J., Kaufman E. L., Neugut A. I., Grann V. R. Randomized trial of black cohosh for the treatment of hot flashes among women with a history of breast cancer. J. Clin. Oncol. 2001; 19: 2739–2745, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Liu J., Burdette J. E., Xu H., Gu C., van Breemen R. B., Bhat K. P., Booth N., Constantinou A. I., Pezzuto J. M., Fong H. H., Farnsworth N. R., Bolton J. L. Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. J. Agric. Food Chem. 2001; 49: 2472–2479, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar
• Kennelly E. J., Baggett S., Nuntanakorn P., Ososki A. L., Mori S. A., Duke J., Coleton M., Kronenberg F. Analysis of thirteen populations of black cohosh for formononetin. Phytomedicine 2002 Jul; 9(5)461–467, [CROSSREF], [CSA]
   PubMed Web of Science ®Google Scholar
• White J. PC-SPES—a lesson for future dietary supplement research. J. Natl. Cancer Inst. 2002; 94: 1261–1263, [PUBMED], [INFOTRIEVE]
   PubMed Web of Science ®Google Scholar
• Blumenthal M. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medications. American Botanical Council, Austin 1998; 90
   Google Scholar