140
Views
27
CrossRef citations to date
0
Altmetric
Research Article

EFFECTS OF TCDD ON THYROID HORMONE HOMEOSTASIS IN THE RAT

Pages 259-277 | Published online: 22 Feb 2000

REFERENCES

  • Huff J. E., Salmon A. G., Hooper N. K., Zeise L. Long-term carcinogenesis studies on 2,3,7,8-tetrachlorodibenzo-p-dioxin and hexachlorodibenzo-p-dioxins. Cell. Biol. Toxicol. 1991; 7: 67–94
  • National Toxicology Program. Carcinogenesis bioassay of 2,3,7,8-tetrachlorodibenzo-p-dioxin in Osborne-Mendel rats and B6C3F1 mice, Technical Report No. 209. 1982
  • Gorski J. R., Rozman K. Dose-response and time course of hypo thyroxemia and hypoinsulinemia and characterization of insulin hyper sensitivity in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treated rats. Toxicology 1987; 44: 297–307
  • Bastomsky C. H. Enhanced thyroxine metabolism and high uptake goiters in rats after a single dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Endocrinology 1977; 101: 292–296
  • Sewall C. H., Flagler N., Heuvel J. P. Vanden, Clark G. C., Tritscher A. M., Maronpot R. M., Lucier G. W. Alterations in thyroid function in female Sprague-Dawley rates following chronic treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Appl. Pharmacol. 1995; 132: 237–244
  • Andrae U., Greim H. Initiation and promotion in thyroid carcinogenesis. Tissue Specific Toxicity: Biochemical Mechanisms. Academic Press, New York 1992; 71–93
  • Hill R. N., Erdreich L. S., Paynter O. E., Roberts P. A., Rosenthal S. L., Wilkinson C. F. Thyroid follicular cell carcinogenesis. Fundam. Appl. Toxicol. 1989; 12: 629–697
  • Bock K. W. Roles of UDP-glucuronosyltransferases in chemical carcino genesis. Crit. Rev. Biochem. Mol. Biol. 1991; 26: 129–150
  • Barter R. A., Klaassen C. D. Rat liver microsomal UDP-glucuronosyltransferase activity toward thyroxine: Characterization, induction, and form specificity. Toxicol. Appl. Pharmacol. 1992; 115: 261–267
  • Kohn M. C., Sewall C. H., Lucier G. W., Portier C. J. A mechanistic model of effects of dioxin on thyroid hormones in the rat. Toxicol. Appl. Pharmacol. 1996; 165: 29–48
  • Kohn M. C. The importance of anatomical realism for validation of physiological models of disposition of inhaled toxicants. Toxicol. Appl. Pharmacol. 1997; 147: 448–458
  • McKinney J. D., Chae K., Oatley S. J., Blake C.C. F. Molecular interactions of toxic chlorinated dibenzo-p-dioxins and dibenzofurans with thyroxine binding prealbumin. J. Med. Chem. 1985; 28: 375–381
  • Albro P. W., Corbett J. T., Harris M., Lawson L. D. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on lipid profiles in tissue of the Fischer rat. Chem.-Biol. Interact. 1978; 23: 315–330
  • Lucier G. W., Tritscher A., Goldsworthy T., Foley J., Clark G., Goldstein J., Maronpot R. Ovarian hormones enhance 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated increases in cell proliferation and preneoplastic foci in a two-stage model for hepatocarcinogenesis. Cancer Res. 1991; 51: 1391–1397
  • Maronpot R. R., Foley J. F., Takahashi K., Goldsworthy T., Clark G., Tritscher A., Portier C., Lucier G. Dose response for TCDD promotion of hepatocarcinogenesis in rats initiated with DEN: Histologic, biochemical, and cell proliferation endpoints. Environ. Health Perspect. 1993; 101: 634–642
  • Tritscher A. M., Goldstein J. A., Portier C. J., McCoy Z., Clark G. C., Lucier G. W. Dose-response relationships for chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in a rat tumor promotion model: Quantification and immunolocalization of CYP1A1 and CYP1A2 in the liver. Cancer Res. 1992; 52: 3436–3442
  • Abrahan K., Krowke R., Neubert D. Pharmacokinetics and biological activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Arch. Toxicol. 1988; 62: 359–368
  • Heuvel J. P. Vanden, Clark G. C., Kohn M. C., Tritscher A. M., Greenlee W. F., Lucier G. W., Bell D. A. Dioxin-responsive genes: examination of dose-response relationships using quantitative reverse transcriptase-polymerase chain reaction. Cancer Res. 1994; 54: 62–68
  • Voorman R., Aust S. D. TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) is a tight binding inhibitor of cytochrome P -450d. J. Biochem. Pharmacol. 1989; 4: 105–109
  • Hotta H., Ooka H., Sato A. Changes in basal secretion rates of thyroxine and 3,3′,5-triiodothyronine from the thyroid gland during aging of the rat. Jpn.J. Physiol. 1991; 41: 75–84
  • Tal E., Kováks Z., Korányi L., Endroóczi E. Morphine induced thy roxine release from rat thyroid gland in vitro. Horm. Metabol. Res. 1986; 18: 238–240
  • Tajima K., Mashita K., Shimizu M., Tarui S. Inhibitory effect of iopanoic acid on the thyrotropin-stimulated release of cyclic adenosine 3′,5′-monophosphate and of 3,5,3′ -triiodothyronine from perifused rat thyroids. Endocrinology 1985; 117: 1813–1817
  • Spira O., Gordon A. Thyroid hormone feedback effects on thyroid-stimulating hormone. Thyroid Hormone Metabolism, G. Hennemann. Dekker, New York 1986; 535–578
  • Labrie F., DeLeaán A., Lagrace L., Drouin J., Beaulieu M., Morin O. Interactions of TRH, LH-RH, and somatostatin in the anterior pituitary gland, III. Receptors and Hormone Action, L. Birnbaumer, B. W. O'Malley. Academic Press, New York 1978; 493–514
  • Gershengorn M. C. Throid hormone regulation of thyrotropin production and interaction with thyrotropin releasing hormone in thyrotropic cells in culture. Molecular Basis of Thyroid Hormone Action, J. H. Oppenheimer, H. H. Samuels. Academic Press, New York 1983; 378–412
  • Shoemaker W. J., Peterfreund R. A., Vale W. Methodological considerations in culturing petidergic neurons. Methods Enzymol. 1983; 103: 347–362
  • Sutherland R. L., Brandon M. R. The thyroxine-binding properties of rat and rabbit serum proteins. Endocrinol. 1976; 98: 91–98
  • Krenning E., Docter R., Bernard B., Visser T., Hennemann G. Characteristics of active transport of thyroid hormone into rat hepatocytes. Biochim. Biophys. Acta. 1981; 676: 314–320
  • Abraham M. H., Kamlet M. J., Taft R. W., Doherty R. M., Weathersby P. K. Solubility properties in polymers and biological media. 2. The correlation and prediction of the solubilities of nonelectrolytes in biological tissues and fluids. J. Med. Chem. 1985; 28: 865–870
  • Lyman W. J., Reehl W. F., Rosenblatt D. H. Handbook of Chemical Property Estimation Methods. Am. Chem. Soc., Washington, DC 1990; 1–27
  • Oppenheimer J. H. The nuclear receptor-triiodothyronine complex: Relationship to thyroid hormone distribution, metabolism, and biological action. Molecular Basis of Thyroid Hormone Action, J. H. Oppenheimber. Academic Press, New York 1983; 1–34
  • Ramsden D. B. Peripheral Metabolism and Action of Throid Hormones. Eden Press, Montreal 1978; 28
  • Aprilletti J. W., David-Inouye Y., Baxter J. D., Eberhardt N. L. Physicochemical characterization of the intranuclear thyroid hormone receptor. Molecular Basis of Thyroid Hormone Action, J. H. Oppenheimer, H. H. Samuels. Academic Press, New York 1987; 67–97
  • Barnes C. P., DeGroot L. J. Nuclear-cytoplasmic interrelationships. Molecular Basis of Thyroid Hormone Action, J. H. Oppenheimer, H. H. Samuels. Academic Press, New York 1987; 139–177
  • Segal J., Ingbar S. H. Extranuclear receptors for thyroid hormones. Thyroid Hormone Metabolism, G. Hennemann. Dekker, New York 1986; 417–439
  • Van Middlesworth L. Metabolism and excretion of thyroid hormones. Handbook of Physiology, Vol. III, Sec. 7: Endocrinology, M. A. Greer, D. H. Solomon. Am. Physiol. Soc., Washington, DC 1974
  • Chopra I. J. New insights into thyroid hormone deiodination. Thyroid Hormone Metabolism, S. -Y. Wu. Blackwell Sci., Boston 1991; 41–54
  • Berry M. J., Larsen P. R. The role of selenium in thyroid hormone action. Endocr. Rev. 1992; 13: 207–219
  • Leonard J. L., Visser T. J. Biochemistry of deiodination. Thyroid Hormone Metabolism, G. Hennemann. Dekker, New York 1986; 189–229
  • Eltom S., Babish J. G., Ferguson D. C. The interaction of L-triiodothy ronine and 2,3,7,8-tetrachlorodibenzo-p-dioxin on Ah-receptor-mediated hepatic phase I and phase II enzymes and iodothyronine 5′ -deiodinase in thy rodectomized rats. Toxicol. Lett. 1992; 61: 125–139
  • Coughtrie M.W. H., Burchell B., Bend J. R. Purification and properties of rat kidney UDP-glucuronosyltransferase. Biochem. Pharmacol. 1987; 36: 245–251
  • Saito K., Kaneko H., Sato K., Yoshitake A., Yamada H. Hepatic UDP-glucuronyl-transferase(s) activity toward thyroid hormones in rats: Induction and effects on serum thyroid hormone levels following treatment with various enzyme inducers. Toxicol. Appl. Pharmacol. 1991; 111: 99–106
  • Kohn M. C., Hines M. L., Kootsey J. M., Feezor M. D. A block organized model builder. Math. Comput. Modelling 1994; 19: 75–97
  • Kootsey J. M., Kohn M. C., Feezor M. D., Mitchell G. R., Fletcher P. R. SCoP: An interactive simulation control program for micro- and minicomputers. Bull. Math. Biol. 1986; 48: 427–441
  • Kohn M. C., Lucier G. W., Clark G. C., Sewall C., Tritscher A., Portier C. J. A mechanistic model of effects of dioxin on gene expression in the rat liver. Toxicol. Appl. Pharmacol. 1993; 120: 138–154
  • Andersen M. E., Mills J. J., Gargas M. L., Kedderis L., Birnbaum L. S., Neubert D., Greenlee W. F. Modeling receptor-mediated processes with dioxin: implications for pharmacokinetics and risk assessment. Risk Anal. 1993; 13: 25–36
  • Pardridge W. M. Transport of protein-bound hormones into tissues in vivo. Endocr. Rev. 1981; 2: 103–123
  • Oppenheimer J. H., Surks M. I. Quantitative aspects of hormone production, distribution, metabolism, and activity. Handbook of Physiology, Vol. III, sec. 7, Endocrinology, J. H. Oppenheimer. Am. Physiol. Soc., Washington, DC 1974; 197–214
  • Chanoine J. -P., Braverman L. E., Farwell A. P., Safran M., Alex S., Dubord S., Leonard J. L. The thyroid gland is a major source of circulating T3 in the rat. J. Clin. Invest. 1993; 91: 2709–2713
  • Larsen P. R., Silva J. E., Kaplan M. M. Relationships between circulating and intracellular thyroid hormones: Physiological and clinical implications. Endocr. Rev. 1981; 2: 87–102
  • McClain R. M. The significance of hepatic microsomal enzyme induction and altered thyroid function in rats: Implications for thyroid gland neoplasia. Toxicol. Pathol. 1989; 17: 294–306
  • Fingerhut M. A., Halperin W. E., Marlow D. A., Piacitelli L., Honchar P. A., Sweeny M. H., Griefe A. L., Dill P. A., Steenland K., Suruda H. Cancer mortality in workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. N. Engl. J. Med. 1991; 324: 212–218
  • Manz A., Berger J., Dwyer J. H., Flesch-Janys D., Nagel S., Waltsgott H. Cancer mortality among workers in chemical plant contaminated with dioxin. Lancet 1991; 338: 959–964
  • Johnson E. S. Important aspects of the evidence for TCDD carcinogenicity in man. Environ. Health Perspect. 1993; 99: 383–390
  • Barter R. A., Klaassen C. D. UDP-glucuronosyltransferase inducers reduce thyroid hormone levels in rats by an extrathyroidal mechanism. Toxicol. Appl. Pharmacol. 1992; 113: 36–42
  • Capan C. C. Pathophysiology of chemical injury of the thyroid gland. Toxicol. Lett. 1992; 64/64: 381–388
  • van Birgelen A.P.J. M., Hébert C. D., Wenk M. L., Grimes L. K., Chapin R. E., Mahler J., Travlos G. S., Bucher J. R. Toxicity of 3,3′,4,4′ -tetrachloroazobenzene in rats and mice. Toxicol. Appl. Pharmacol., in press, 1999
  • van Birgelen A.P.J. M., Hébert C. D., Wenk M. L., Grimes L. K., Chapin R. E., Mahler J., Travlos G. S., Bucher J. R. Toxicity of 3,3′,4,4′ -tetrachloroazoxybenzene in rats and mice. Toxicol. Appl. Pharmacol., in press, 1999
  • Delp M. D., Manning R. O., Bruckner J. V., Armstrong R. B. Distribution of cardiac output during diurnal changes of activity in rats. Am. J. Physiol. 1991; 261: H1487–H1493
  • Pohjanvirta R., Kulju T., Morselt A.F. W., Tuominen R., Juvonen R., Rozman K., Männisto P., Collan Y., Sainio e. -L., Tuomisto J. Target tissue morphology and serum biochemistry following 2,3,7,8-tetra chlorodibenzo-p-dioxin (TCDD) exposure in a TCDD-susceptible and a TCDD-resistant rat strain. Fundam. Appl. Pharmacol. 1989; 12: 272–590
  • Piva F., Steiner H. Bioassay and toxicology of TRH. Front. Horm. Res. 1972; 1: 11–21
  • Altman P. L., Dittmer D. S. Biological Handbooks, Respiration and Circulation. Federation of American Societies for Experimental Biology. Bethesda, MD 1971; 384–385
  • Lucier G. W., Rumbaugh R. C., McCoy Z., Hass R., Harvan D., Albro P. Ingestion of soil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters hepatic enzyme activities in rats. Fundam. Appl. Toxicol. 1986; 6: 364–371
  • Lucier G. W., McDaniel O. S., Hook G.E. R., Fowler B. A., Sonawane B. R., Faeder E. TCDD-induced changes in rat liver microsomal enzymes. Environ. Health Perspect. 1973; 5: 199–209
  • Bank P., Salyers K. L., Zile M. H. Effect of tetrachlorodibenzo-p-dioxin (TCDD) on the glucuronidation of retinoic acid in the rat. Biochim. Biophys Acta 1989; 993: 1–6

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.