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Research Article

EVIDENCE FOR AND ROLE OF THE DIMETHYLAMINO GROUP IN TAMOXIFEN DNA INTERCALATION IN INTACT CHINESE HAMSTER V79 CELLS

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Pages 473-479 | Published online: 09 Mar 2002

REFERENCES

  • Phillips D.H. Understanding the Genotoxicity of Tamoxifen?. Carcinogenesis 2001; 22: 839–849
  • Hellmann-Blumberg U., Cartner M.G., Wurz G.T., DeGregorio M.W. Intrinsic Reactivity of Tamoxifen and Toremifene Metabolites with DNA. Breast Cancer Res. Treat. 1998; 50: 135–141
  • Snyder R.D., Strekowski L. Enhancement of Bleomycin-Induced Micronucleus Formation in V79 Cells as a Rapid and Sensitive Screen for Non-covalent DNA-Binding Compounds. Mutat. Res. 1999; 444: 181–192
  • Snyder R.D. A Review and Investigation Into the Mechanistic Basis of the Genotoxicity of Antihistamines. Mutat. Res. 1998; 411: 235–248
  • Snyder R.D., Diehl M.S. The Bleomycin Amplification Assay in V79 Cells Predicts Frameshift Mutagenicity of Intercalative Agents. Mutagenesis 2000; 15: 203–205
  • Edwards M.L., Snyder R.D., Stemerick D.M. Synthesis and DNA Binding Properties of Polyamine Analogs. J. Med. Chem. 1991; 34: 2414–2420
  • Styles J.A., Davies A., Davies R., White I.H.N., Smith L.L. Clastogenic and Aneugenic Effects of Tamoxifen and Some of its Analogs in Hepatocytes from Dosed Rats and in Human Lymphoblastoid Cells Transfected with Human P450 cDNAs (MCL-5 cells). Carcinogenesis 1997; 18: 303–313
  • Snyder R.D., Arnone M.R. Putative Identification of Functional Interactions Between DNA Intercalating Agents and Topoisomerase II Using the V79 In Vitro Micronucleus Assay. Mutat. Res., In Press

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