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Drug Development and Industrial Pharmacy Volume 25, 1999 - Issue 11
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Research Article

Percutaneous Transport of Diclofenac Sodium from Mixtures of Fatty Alcohol (or Fatty Acid) and Propylene Glycol Through the Rabbit Abdominal Skin

Chi-Yin Wong Department of Orthopaedics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, R.O.C.
,
Yih-Bin Guu Department of Pharmacy, Tri-Service General Hospital, Taipei, Taiwan, R.O.C.
,
Meng-Ting Wang Department of Orthopaedics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, R.O.C.
&
Da-Peng Wang School of Pharmacy, National Defense Medical Center, Taipei, Taiwan, R.O.C.
Pages 1209-1213 | Published online: 22 Nov 1999

REFERENCES

  • Koichi T., Satoko T., Toyoshi K., Hironori Y., Akira K. J., Howard R., Toshiaki N., Nobuyasu M. In vitro percutaneous transport of sodium diclofenac and diclofenac from oleaginous vehicle. Chem. Pharm. Bull. 1991; 39(2)509–511
  • Mutsuo O., Kenji S., Keiaburo O., Yasunori M. Skin permeability of water-soluble drugs. Chem. Pharm. Bull. 1989; 37(5)1404–1406
  • Barry B. W. Continuous shear, viscoelastic and spreading properties of a new topical vehicle, FAPG base. J. Pharm. Pharmacol. 1973; 25: 131–137
  • Katz M., Neiman H. M., U.S. Pat. 3592930, 1971
  • Davis S. S. Is pharmaceutical rheology dead?. Pharm. Acta. Helv. 1974; 49: 161–168
  • Turi J. S., Danielson D., Woltersom J. W. Effects of polyoxypropylene 15 stearyl ether and propylene glycol on percutaneous penetration rate of diflorasone diacetate. J. Pharm. Bull. 1979; 35: 275–280
  • Kaiho F., Nomura H., Makabe E., Kato Y. Percutaneous absorption of indomethacin from mixtures of fatty alcohol and propylene glycol (FAPG bases) through rat skin: effects of fatty acid to FAPG base. Chem. Pharm. Bull. 1987; 35: 2928–2934
  • Aungst B. J., Rogers N. J., Shefter E. Enhancement of naloxone penetration through human skin in vitro using fatty acid, fatty alcohol, surfactants, sulfoxides and amides. Int. J. Pharm. 1986; 33: 225–234
  • Komata Y., Inaoka M., Kaneko A., Fujie T. In vitro percutaneous absorption of thiamine disulfide from a mixture of propylene glycol and fatty acid. J. Pharm. Sci. 1985; 81: 123–132

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