Advanced search
Publication Cover
Drug Development and Industrial Pharmacy Volume 28, 2002 - Issue 8
Submit an article Journal homepage
58
Views
16
CrossRef citations to date
0
Altmetric
Research Article

The Effect of Storage Temperatures on the In Vitro Properties of a Polyanhydride Implant Containing Gentamicin

Y. Tian Drug Delivery, Alcon Laboratories, R2-45, 6201 South Freeway, Fort Worth, Texas, 76134–2099, U.S.A.
,
L. Li Advanced Drug Delivery, Hospital Products Division, Dept. 97d, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois, 60064-3500, U.S.A.
,
X. Gao Advanced Drug Delivery, Hospital Products Division, Dept. 97d, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois, 60064-3500, U.S.A.
,
J. Deng Advanced Drug Delivery, Hospital Products Division, Dept. 97d, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois, 60064-3500, U.S.A.
,
D. Stephens Advanced Drug Delivery, Hospital Products Division, Dept. 97d, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois, 60064-3500, U.S.A.
,
D. Robinson Advanced Drug Delivery, Hospital Products Division, Dept. 97d, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois, 60064-3500, U.S.A.
&
H. Chang Advanced Drug Delivery, Hospital Products Division, Dept. 97d, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois, 60064-3500, U.S.A.
 show all
Pages 897-903 | Published online: 28 Aug 2002

REFERENCES

  • Bohner M., Lemaitre J., Van Landuyt P., Zambelli P.Y., Merkle H.P., Gander B. Gentamicin-Loaded Hydraulic Calcium Phosphate Cement as Antibiotic Delivery System. J. Pharm. Sci. 1997; 86(5)565–572
  • van de Belt H., Neut D., Schenk W., van Horn J.R., van der Mei H.C., Busscher H.J. Gentamicin Release from Polymethylmethacrylate Bone Cement and Staphylococcus aureus Biofilm Formation. Acta Ortho. Scand. 2000; 71(6)625–629
  • Ethell M.T., Bennett R.A., Brown M.P., Merritt K., Davidson J.S., Tran T. In Vitro Elution of Gentamicin, Amikacin, and Ceftiofur from Polymethylmethacrylate and Hydroxyapatite Cement. Vet. Surg. 2000; 29(5)375–382
  • Chasin M. Biodegradable Polymers for Controlled Drug Delivery. Biomedical Applications of Synthetic Biodegradable Polymers, J.O. Hollinger. CRC, Boca Raton, FL 1995; 1–15
  • Hayashi T. Biodegradable Polymers for Biomedical Uses. Progr. Polym. Sci. 1994; 19(4)663–700
  • Tamada J., Langer R. The Development of Polyanhydrides for Drug Delivery Applications. J. Biomater. Sci. Polym. Ed. 1992; 3(4)315–353
  • Shieh L., Tamada J., Chen I., Pang J., Domb A., Langer R. Erosion of a New Family of Biodegradable Polyanhydride. J. Biomed. Mater. Res. 1994; 28: 1465–1475
  • Park E., Maniar M., Shah J. Influence of Physicochemical Properties of Model Compounds on Their Release from Biodegradable Polyanhydride Devices. J. Contr. Rel. 1997; 48: 67–78
  • Tabata Y., Gutta S., Langer R. Controlled Delivery Systems for Proteins Using Polyanhydride Micro- spheres. Pharm. Res. 1993; 10(4)487–496
  • Thomas P.A., Padmaja T., Kulkarni M.G. Polyanhydride Blend Microspheres: Novel Carriers for the Controlled Release of Macromolecular Drugs. J. Contr. Rel. 1997; 43(2–3)273–281
  • Domb A.J., Amselem S. Antibiotic Delivery Systems for the Treatment of Chronic Bone Infections. Polymer Site-Specific Pharmacotherapy. Wiley, ChichesterUK 1994
  • Laurencin C.T., Gerhart T., Witschger P., Satcher R., Domb A., Rosenberg A.E., Hanff P., Edsberg L., Hayes W., Langer R. Bioerodible Polyanhydrides for Antibiotic Drug Delivery: In Vivo Osteomyelitis Treatment in a Rat Model System. J. Ortho. Res. 1993; 11(2)256–262
  • Nelson C.L., Hickmon S.G., Skinner R.A. Treatment of Experimental Osteomyelitis by Surgical Debridement and the Implantation of Bioerodible, Polyanhydride–Gentamicin Beads. J. Ortho. Res. 1997; 15: 249–255
  • Domb A., Langer R. Solid-State and Solution Stability of Polyanhydrides and Poly(esters). Macromolecules 1989; 22(5)2117–2122
  • Stephens D., Li L.C., Robinson D., Chen S., Chang H., Liu R., Tian Y., Ginsburg E., Gao X., Stultz T. Investigation of the In-Vitro Release of Gentamicin from a Polyanhydride Matrix. J. Contr. Rel. 2000; 63: 305–317
  • Welsh W.J. Thermal–Oxidative Stability and Degradation of Polymers. Physical Properties of Polymers Handbook, J.M. Mark. American Institute of Physics, Woodbury, NY 1996; 611

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.