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Research Article

An Explanation for the Physical Instability of a Marketed Fixed Dose Combination (FDC) Formulation Containing Isoniazid and Ethambutol and Proposed Solutions

, Ph.D., & , Ph.D.
Pages 667-672 | Published online: 03 Jun 2004

References

  • Singh S., Bhutani H., Mariappan T. T., Kaur H., Bajaj M., Pakhale S. P. Behavior of uptake of moisture by drugs and excipients under accelerated conditions of temperature and humidity in the absence and the presence of light. 1. Pure anti‐tuberculosis drugs and their combinations. Int. J. Pharm. 2002; 245: 37–44, [PUBMED], [INFOTRIEVE]
  • Bhutani H., Mariappan T. T., Singh S. Behavior of uptake of moisture by drugs and excipients under accelerated conditions of temperature and humidity in the absence and the presence of light. Part II. Packaged and unpackaged anti‐tuberculosis drug products. Pharm. Technol. 2003; 27(6)44–52
  • Kaur H., Mariappan T. T., Singh S. Behavior of uptake of moisture by drugs and excipients under accelerated conditions of temperature and humidity in the absence and the presence of light. Part III. Different drug substances and excipients. Pharm. Technol. 2003; 27(12)52–56
  • Stability Testing of the New Drug Substances and Products. ICH, Geneva 2003; Vol. [Q1A (R2)]
  • Mohan B., Sharda N., Singh S. Evaluation of recently reported USP gradient method for anti‐tuberculosis drugs in FDCs for its ability to resolve degradation products of rifampicin. J. Pharm. Biomed. Anal. 2003; 31: 607–612, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Takka S. Propranolol hydrochloride‐anionic polymer binding interaction. I.L. Farmaco. 2003; 58: 1051–1056, [CROSSREF]

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