Advanced search
Publication Cover
Drug Development and Industrial Pharmacy Volume 30, 2004 - Issue 10
Submit an article Journal homepage
164
Views
5
CrossRef citations to date
0
Altmetric
Research Article

Multivariate Methods in the Development of a New Tablet Formulation: Optimization and Validation

Jon Gabrielsson Research Group for Chemometrics, Department of Chemistry, Umeå University, Umeå, SE‐901 87, Sweden
,
Nils‐Olof Lindberg Pharmacia AB, Consumer Healthcare, Box 941, Helsingborg, SE‐251 09, Sweden
,
Magnus Pålsson Pharmacia AB, Consumer Healthcare, Box 941, Helsingborg, SE‐251 09, Sweden
,
Fredrik Nicklasson Pharmacia AB, Consumer Healthcare, Box 941, Helsingborg, SE‐251 09, Sweden
,
Michael Sjöström Research Group for Chemometrics, Department of Chemistry, Umeå University, Umeå, SE‐901 87, Sweden
&
Torbjörn Lundstedt Department of Medicinal Chemistry, Uppsala University, Box 574, Uppsala, 751 23, Sweden
Pages 1037-1049 | Published online: 11 Apr 2004

References

  • Wold S., Sjöström M., Carlson R., Lundstedt T., Hellberg S., Skagerberg B., Wikström C., Öhman J. Multivariate design. Anal. Chim. Acta 1986; 191: 17–32
  • Gabrielsson J., Lindberg N.‐O., Pålsson M., Nicklasson F., Sjöström M., Lundstedt T. Multivariate methods in the development of a new tablet formulation. Drug Dev. Ind. Pharm. 2003; 29(10)1053–1075
  • Peck G. E., Baley G. J., McCurdy V. E., Banker G. S. Tablet formulation and design. Pharmaceutical Dosage Forms2nd Ed., H. A. Lieberman, L. Lachman, J. B. Schwartz. Marcel Dekker, Inc., New York 1989
  • Pasikatan M. C., Steele J. L., Spillman C. K., Haque E. Near infrared reflectance spectroscopy for online particle size analysis of powders and ground materials. J. Near Infrared Spectrosc. 2001; 9(3)153–164
  • Rhodes C. T., Morisseau K. Tablet evaluation using near‐infrared spectroscopy. Encyclopedia of Pharmaceutical Technology, J. Swarbrick, J. C. Boylan. Marcel Dekker, Inc., New York 2002; Vol. 3: 2689–2700
  • Andre M. Multivariate analysis and classification of the chemical quality of 7‐aminocephalosporanic acid using near‐infrared reflectance spectroscopy. Anal. Chem. 2003; 75: 3460–3467
  • Gustafsson C., Nyström C., Lennholm H., Bonferoni M. C., Caramella C. M. Characteristics of hydroxypropyl methylcellulose influencing compactibility and prediction of particle and tablet properties by infrared spectroscopy. J. Pharm. Sci. 2003; 92(3)460–470
  • Website F., http://www.accessdata.fda.gov/scripts/cder/iig/index.cfm
  • Lundstedt T., Seifert E., Abramo L., Thelin B., Nyström Å., Pettersen J., Bergman R. Experimental design and optimization. Chem. Intell. Lab. Sys. 1998; 42: 3–40
  • Harcum W. W., Skinner G. W., Altekar M., Joneja S. K., Barnum P. E., Guo J.‐H. Modeling the effects of hydroxypropylcellulose in acetaminophen tablet formulation. Drug Dev. Ind. Pharm. 1998; 24(10)911–918

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.