383
Views
60
CrossRef citations to date
0
Altmetric
Research Article

Isothiocyanates in Cancer Prevention

&
Pages 655-667 | Published online: 25 Oct 2004

References

  • Benhamou S., Lee W. J., Alexandrie A. K., Boffetta P., Bouchardy C., Butkiewicz D., Brockmoller J., Clapper M. L., Daly A., Dolzan V., Ford J., Gaspari L., Haugen A., Hirvonen A., Husgafvel‐Pursiainen K., Ingelman‐Sundberg M., Kalina I., Kihara M., Kremers P., Le Marchand L., London S. J., Nazar‐Stewart V., Onon‐Kihara M., Rannug A., Romkes M., Ryberg D., Seidegard J., Shields P., Strange R. C., Stucker I., To‐Figueras J., Brennan P., Taioli E. Meta‐ and pooled analyses of the effects of glutathione S‐transferase M1 polymorphisms and smoking on lung cancer risk. Carcinogenesis 2002; 23(8)1343–1350, [PUBMED], [INFOTRIEVE]
  • Brüsewitz G., Cameron B. D., Chasseaud L. F., Görler K., Hawkins D. R., Koch H. The metabolism of benzyl isothiocyanate and its cysteine conjugate. Biochem. J. 1977; 162: 99–107
  • Chung F. L., Morse M. A., Eklind K. I., Lewis J. Quantitation of human uptake of the anticarcinogen phenethyl isothiocyanate after a watercress meal. Cancer Epidemiol. Biomark. Prev. 1992; 1(5)383–388
  • Conaway C. C., Jiao D., Kohri T., Liebes L., Chung F. L. Disposition and pharmacokinetics of phenethyl isothiocyanate and 6‐phenylhexyl isothiocyanate in F344 rats. Drug Metab. Dispos. 1999; 27(1)13–20, [PUBMED], [INFOTRIEVE], [CSA]
  • Conaway C. C., Getahun S. M., Liebes L. L., Pusateri D. J., Topham D. K., Botero‐Omary M., Chung F. L. Disposition of glucosinolates and sulforaphane in humans after ingestion of steamed and fresh broccoli. Nutr. Cancer 2000; 38(2)168–178, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Fowke J. H., Fahey J. W., Stephenson K. K., Hebert J. R. Using isothiocyanate excretion as a biological marker of Brassica vegetable consumption in epidemiological studies: evaluating the sources of variability. Public Health Nutr. 2001; 4(3)837–846, [PUBMED], [INFOTRIEVE], [CSA]
  • Fowke J. H., Qi D., Bradlow H. L., Shu X. O., Gao Y. T., Cheng J. R., Jin F., Zheng W. Urinary estrogen metabolites and breast cancer: differential pattern of risk found with pre‐ vs. post‐treatment collection. Steroids 2003; 68(1)65–72, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Garte S., Gaspari L., Alexandrie A. K., Ambrosone C., Autrup H., Autrup J. L., Baranova H., Bathum L., Benhamou S., Boffetta P., Bouchardy C., Breskvar K., Brockmoller J., Cascorbi I., Clapper M. L., Coutelle C., Daly A., Dell'Omo M., Dolzan V., Dresler C. M., Fryer A., Haugen A., Hein D. W., Hildesheim A., Hirvonen A., Hsieh L. L., Ingelman‐Sundberg M., Kalina I., Kang D., Kihara M., Kiyohara C., Kremers P., Lazarus P., Le Marchand L., Lechner M. C., Van Lieshout E. M., London S., Manni J. J., Maugard C. M., Morita S., Nazar‐Stewart V., Noda K., Oda Y., Parl F. F., Pastorelli R., Persson I., Peters W. H., Rannug A., Rebbeck T., Risch A., Roelandt L., Romkes M., Ryberg D., Salagovic J., Schoket B., Seidegard J., Shields P. G., Sim E., Sinnet D., Strange R. C., Stucker I., Sugimura H., To‐Figueras J., Vineis P., Yu M. C., Taioli E. Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiol. Biomark. Prev. 2001; 10(12)1239–1248, [CSA]
  • Getahun S. M., Chung F. L. Conversion of glucosinolates to isothiocyanates in humans after ingestion of cooked watercress. Cancer Epidemiol. Biomark. Prev. 1999; 8(5)447–451, [CSA]
  • Görler K., Krumbiegel G., Mennicke W. H., Siehl H. U. The metabolism of benzyl isothiocyanate and its cysteine conjugate in guinea‐pigs and rabbits. Xenobiotica 1982; 12: 535–542, [CSA]
  • Hecht S. S. Inhibition of carcinogenesis by isothiocyanates. Drug Metab. Rev. 2000; 32(3–4)395–411, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • IARC. IARC handbooks of cancer prevention. Cruciferous Vegetables, Isothiocyanates, and Indoles. IARC Press, LyonFrance 2004; Volume 9
  • Ioannou Y. M., Burka L. T., Mattews H. B. Allyl isothiocyanate: comparative disposition in rats and mice. Toxicol. Appl. Pharmacol. 1984; 75: 173–181, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Ji Y., Morris M. E. Determination of phenethyl isothiocyanate in human plasma and urine by ammonia derivatization and liquid chromatography–tandem mass spectrometry. Anal. Biochem. 2003; 323(1)39–47, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Jiao D., Yu M. C., Hankin J. H., Low S. H., Chung F. L. Total isothiocyanate contents in cooked vegetables frequently consumed in Singapore. J. Agric. Food Chem. 1998; 46: 1055–1058, [CROSSREF]
  • Liebes L., Conaway C. C., Hochster H., Mendoza S., Hecht S. S., Crowell J., Chung F. L. High‐performance liquid chromatography‐based determination of total isothiocyanate levels in human plasma: application to studies with 2‐phenethyl isothiocyanate. Anal. Biochem. 2001; 291(2)279–289, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • London S. J., Yuan J. M., Chung F. L., Gao Y. T., Coetzee G. A., Ross R. K., Yu M. C. Isothiocyanates, glutathione S‐transferase M1 and T1 polymorphisms, and lung‐cancer risk: a prospective study of men in Shanghai, China. Lancet 2000; 356(9231)724–729, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Mennicke W. H., Görler K., Krumbiegel G. Metabolism of some naturally occurring isothiocyanates in the rat. Xenobiotica 1983; 13(4)203–207, [PUBMED], [INFOTRIEVE]
  • Mennicke W. H., Görler K., Krumbiegel G., Lorenz D., Rittmann N. Studies on the metabolism and excretion of benzyl isothiocyanate in man. Xenobiotica 1988; 18(4)441–447, [PUBMED], [INFOTRIEVE]
  • Negrusz A., Moore C. M., McDonagh N. S., Woods E. F., Crowell J. A., Levine B. S. Determination of phenethylamine, a phenethyl isothiocyanate marker, in dog plasma using solid‐phase extraction and gas chromatography–mass spectrometry with chemical ionization. J. Chromatogr., B, Biomed. Sci. Appl. 1998; 718(1)193–198, [CROSSREF]
  • Rosa E. A., Heaney R. K., Fenwick G. R., Portas C. A. Glucosinolates in crop plants. Hortic. Rev. 1997; 19: 99–215
  • Rouzaud G., Rabot S., Ratcliffe B., Duncan A. J. Influence of plant and bacterial myrosinase activity on the metabolic fate of glucosinolates in gnotobiotic rats. Br. J. Nutr. 2003; 90(2)395–404, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Seow A., Shi C. Y., Chung F. L., Jiao D., Hankin J. H., Lee H. P., Coetzee G. A., Yu M. C. Urinary total isothiocyanate (ITC) in a population‐based sample of middle‐aged and older Chinese in Singapore: relationship with dietary total ITC and glutathione S‐transferase M1/T1/P1 genotypes. Cancer Epidemiol. Biomark. Prev. 1998; 7(9)775–781, [CSA]
  • Seow A., Poh W. T., Teh M., Eng P., Wang Y. T., Tan W. C., Chia K. S., Yu M. C., Lee H. P. Diet, reproductive factors and lung cancer risk among Chinese women in Singapore: evidence for a protective effect of soy in nonsmokers. Int. J. Cancer 2002; 97(3)365–371, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Shapiro T. A., Fahey J. W., Wade K. L., Stephenson K. K., Talalay P. Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables. Cancer Epidemiol. Biomark. Prev. 1998; 7(12)1091–1100, [CSA]
  • Shapiro T. A., Fahey J. W., Wade K. L., Stephenson K. K., Talalay P. Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: metabolism and excretion in humans. Cancer Epidemiol. Biomark. Prev. 2001; 10(5)501–508, [CSA]
  • Spitz M. R., Duphorne C. M., Detry M. A., Pillow P. C., Amos C. I., Lei L., de Andrade M., Gu X., Hong W. K., Wu X. Dietary intake of isothiocyanates: evidence of a joint effect with glutathione S‐transferase polymorphisms in lung cancer risk. Cancer Epidemiol. Biomark. Prev. 2000; 9(10)1017–1020, [CSA]
  • Vermeulen M., Van Rooijen H. J., Vaes W. H. Analysis of isothiocyanate mercapturic acids in urine: a biomarker for cruciferous vegetable intake. J. Agric. Food Chem. 2003; 51(12)3554–3559, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Ye L., Dinkova‐Kostova A. T., Wade K. L., Zhang Y., Shapiro T. A., Talalay P. Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans. Clin. Chim. Acta 2002; 316(1–2)43–53, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Zhang Y. Role of glutathione in the accumulation of anticarcinogenic isothiocyanates and their glutathione conjugates by murine hepatoma cells. Carcinogenesis 2000; 21(6)1175–1182, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Zhang Y. Molecular mechanism of rapid cellular accumulation of anticarcinogenic isothiocyanates. Carcinogenesis 2001; 22(3)425–431, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Zhang Y., Talalay P. Anticarcinogenic activities of organic isothiocyanates: chemistry and mechanisms. Cancer Res. 1994; Suppl. 54: 1976s–1981s
  • Zhang Y., Talalay P. Mechanism of differential potencies of isothiocyanates as inducers of anticarcinogenic phase 2 enzymes. Cancer Res. 1998; 58(20)4632–4639, [PUBMED], [INFOTRIEVE]
  • Zhang Y., Callaway E. C. High cellular accumulation of sulphoraphane, a dietary anticarcinogen, is followed by rapid transporter‐mediated export as a glutathione conjugate. Biochem. J. 2002; 364(Pt. 1)301–307, [PUBMED], [INFOTRIEVE], [CSA]
  • Zhang Y., Cho C. G., Posner G. H., Talalay P. Spectroscopic quantitation of organic isothiocyanates by cyclocondensation with vicinal dithiols. Anal. Biochem. 1992; 205(1)100–107, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Zhang Y., Kolm R. H., Mannervik B., Talalay P. Reversible conjugation of isothiocyanates with glutathione catalyzed by human glutathione transferases. Biochem. Biophys. Res. Commun. 1995; 206(2)748–755, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Zhang Y., Wade K. L., Prestera T., Talalay P. Quantitative determination of isothiocyanates, dithiocarbamates, carbon disulfide, and related thiocarbonyl compounds by cyclocondensation with 1,2‐benzenedithiol. Anal. Biochem. 1996; 239(2)160–167, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Zhao B., Seow A., Lee E. J., Poh W. T., Teh M., Eng P., Wang Y. T., Tan W. C., Yu M. C., Lee H. P. Dietary isothiocyanates, glutathione S‐transferase‐M1, ‐T1 polymorphisms and lung cancer risk among Chinese women in Singapore. Cancer Epidemiol. Biomark. Prev. 2001; 10(10)1063–1067, [CSA]

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.