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Hemoglobin
international journal for hemoglobin research
Volume 25, 2001 - Issue 4
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Original

INTERACTION OF THE α2 POLYADENYLATION SIGNAL MUTATION (AATAAA → AATA– –) AND α0-THALASSEMIA (– –SEA), RESULTING IN Hb H DISEASE IN A THAI PATIENT

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Pages 383-389 | Received 01 Jun 2001, Accepted 16 Jul 2001, Published online: 07 Jul 2009

REFERENCES

  • Wasi P., Na-Nakorn S, Pootrakul S. The α Thalassaemias. Clin. Haematol. 1974; 3: 383–410
  • Laosombat V. Thalassemia in Children in Southern Thailand. J. Med. Assoc. Thai. 1986; 69: 393–399
  • Wongchanchailert M., Laosombat V., Maipang M. Hemoglobin H Disease in Children. J. Med. Assoc. Thai. 1992; 75: 611–618
  • Higgs D. R., Goodbourn S. E.Y., Lamb J., Clegg J. B., Weatherall D. J. α-Thalassaemia caused by a Polyadenylation Signal Mutation. Nature 1983; 306: 398–400
  • Thein S. L., Wallace R. B., Pressley L., Clegg J. B., Weatherall D. J., Higgs D. R. The Polyadenylation Site Mutation in the α-globin Gene Cluster. Blood 1988; 71: 313–319
  • Yüregir G. T., Aksoy K., Cürük M. A., Dikmen N., Fei Y. J., Baysal E., Huisman T. H.J. Hb H Disease in a Turkish Family Resulting from the Interaction of a Deletional α-Thalassaemia-1 and a Newly Discovered Poly A Mutation. Br. J. Haematol. 1992; 80: 527–532
  • Harteveld C. L., Losekoot M., Haak H., Heister J. G.A.M., Giordano P. C., Bernini L. F. A Novel Polyadenylation Signal Mutation in the α2-globin Gene Causing α-Thalassaemia. Br. J. Haematol. 1994; 87: 139–143
  • Giordano P. C., Harteveld C. L., Bok L. A., van Delft A., Batelaan D., Beemer F. A., Bernini L. F. A Complex Haemoglobinopathy Diagnosis in a Family with Both β0- and α0/+-Thalassaemia Homozygosity. Eur. J. Hum. Genet. 1999; 7: 163–168
  • Chan V., Chan V. W.Y., Tang M., Lau K., Todd D., Chan T. K. Molecular Defects in Hb H Hydrops Fetalis. Br. J. Haematol. 1997; 96: 224–228
  • Fucharoen G., Fucharoen S. P. Rapid and Simultaneous Non-radioactive Method for Detecting α-thalassaemia 1 (SEA type) and Hb Constant Spring Genes. Eur. J. Haematol 1994; 53: 186–187
  • Baysal E., Kleanthous M., Bozkurt G., Kyrri A., Kalogirou E., Angastiniotis M., Ioannou P., Huisman T. H.J. α-Thalassaemia in the Population of Cyprus. Br. J. Haematol. 1995; 89: 496–499
  • öner C., Gürgey A., Öner R., Balkam H., Gümrük F., Baysal E., Altay Ç. The Molecular Basis of Hb H Disease in Turkey. Hemoglobin 1997; 21(1))41–51
  • Galanello R., Paglietti E., Melis M. A., Crobu M. G., Addis M., Moi P., Cao A. Interaction of Heterozygous β0-Thalassemia with Single Functional α-globin Gene. Am. J. Hematol., 1988(29)63–66
  • Whitelaw E., Proudfoot N. α-Thalassemia caused by a Poly (A) Site Mutation Reveals that Transcriptional Termination is Linked to 3′ End Processing in the Human α2-globin. Gene. EMBO J. 1986; 5: 2915–2922
  • Morales J., Russel J. E., Liebhaber S. A. Destabilization of Human α-Globin mRNA by Translation Anti-termination is Controlled During Erythroid Differentiation and is Paralleled by Phased Shortening of the Poly (A). Tail. J. Biol. Chem 1997; 272: 6607–6613
  • Chen F. E., Ooi C., Ha S. Y., Cheung B. M.Y., Todd D., Liang R., Chan T. K., Chan V. Genetic and Clinical Features of Hemoglobin H Disease in Chinese Patients. N. Engl. J. Med. 2000; 343: 544–550

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