Publication Cover
Hemoglobin
international journal for hemoglobin research
Volume 26, 2002 - Issue 3
92
Views
2
CrossRef citations to date
0
Altmetric
Original

α-THALASSEMIA DOES NOT SIGNIFICANTLY CONTRIBUTE TO THE LOW MCV LEVEL OF Hb C TRAIT

, , &
Pages 305-309 | Received 29 Oct 2001, Accepted 12 Apr 2002, Published online: 07 Jul 2009

REFERENCES

  • Williams W. J., Beutler E., Erlev A. J., Lichtman M. A. Hematology. McGraw Hill Book Company:New York, NYUSA 2001, 6th Ed.
  • Ballas S. K., Kocher W. Erythrocytes in Hb SC Disease are Microcytic and Hyperchromic. Am. J. Hematol. 1988; 28(1)37–39
  • Stamatoyannopoulus G., Nienhis A. W., Majerus P. W. The Molecular Basis of Blood Disease. W.B. Saunders Company:Philadelphia, , PA, USA 1994, 2nd Ed.
  • Bunn H. F., Forget B. G. Hemoglobin: Molecular, Genetic and Clinical Aspects. W.B. Saunders Company:Philadelphia, , PA, USA 1986
  • Fabry M. E., Kaul D. K., Raventos C., Baez S., Rieder R., Nagel R. L. Some Aspects of the Pathophysiology of Homozygous Hb CC Erythrocytes. J. Clin. Invest. 1981; 67(5)1284–1291
  • Hirsch R. E., Suarez C. R., Olson J. A., Nagel R. L. Ligand State of Intraerythrocytic Circulating Hb C Crystals in Homozygote CC Patients. Blood 1985; 66(4)775–777
  • Lawrence C., Fabry M. E., Nagel R. L. The Unique Red Cell Heterogeneity of SC Disease: Crystal Formation, Dense Reticulocytes, and Unusual Morphology. Blood 1991; 78(8)2104–2112
  • Steinberg M. H. Haemoglobin C/α-Thalassaemia: Haematological and Biosynthetic Studies. Br. J. Haematol 1975; 30(3)337–342
  • Walker B. K., Atwater J., Ballas S. K. Interaction of α-Thalassemia Genes with Each Other and with Hb C in an American Black Family. Biochem. Genet. 1979; 17 (11&12): 1021–1029
  • Flint J., Hill A.V. S., Bowden D. K., Oppenheimer S. J., Sill P. R., Serjeatson S. W., Bana-Koiri J., Bhatia K., Alpers M. P., Boyce A. J., Weatherall D. J., Clegg J. B. High Frequencies of α-Thalassaemia Are the Result of Natural Selection by Malaria. Nature 1986; 321(6072)744–750
  • Nagel R. L., Steinberg M. H. Hemoglobin SC Disease and Hb C Disorders. Disorders of Hemoglobin. Genetics, Pathophysiology, and Clinical Management, M. H. Steinberg, B. G. Forget, D. R. Higgs, R. L. Nagel. Cambridge University Press:, CambridgeUK 2001
  • Sonati M. F., Kimura E. M., Grotto H.Z. W., Gervàsio S. A., Costa F. F. Hereditary Hemoglobinopathies in a Population from Southeast Brazil. Hemoglobin 1996; 20(2)175–179
  • Sonati M. F., Farah S. B., Ramalho A. S., Costa F. F. High Prevalence of α-Thalassemia in a Black population of Brazil. Hemoglobin 1991; 15(4)309–311
  • Sonati M. F., Kimura E. M., Costa F. F. Red Cell Indices and α-Thalassemia. Brazil J. Genet. 1992; 15(3)687–693
  • Dacie J. V., Lewis S. M. Pratical Haematology. Churchill Livingstone:, EdinburghUK 1995, 6th Ed.
  • Dodé C., Krishnamoorthy R., Lamb J., Rochette J. Rapid Analysis of -α3.7 Thalassaemia and αααanti3.7 Triplication by Enzymatic Amplification Analysis. Br. J. Haematol. 1993; 83(1)105–111
  • Conover W. J. Practical Nonparametric Statistics. John Wiley & Sons:New York, NYUSA 1971
  • Steinberg M. H., Coleman M. B., Adams J. G., Platica O., Gillette P. The Effects of α-Thalassaemia in Hb SC disease. Br. J. Haematol. 1983; 55(3)487–492
  • Lee K., Préhu C., Mérault G., Kéclard L., Roudot-Thoraval F., Bachir D., Wajcman H., Denis L., Galactéros F. Genetic and Hematological Studies in a Group of 114 Adult Patients With SC Sickle Cell Disease. Am. J. Hematol. 1998; 59(1)15–21
  • Nagel R. L., Lin M. J., Witkowska H. E., Fabry M. E., Bestak M., Hirsch R. E. Compound Heterozygosity for Hemoglobins C and Korle-Bu: Moderate Microcytic Hemolytic Anemia and Acceleration of Crystal Formation. Blood 1993; 82(6)1907–1912
  • Fabry M. E., Romero J. R., Suzuka S. M., Gilman J. G., Feeling-Taylor A., Odunusi E., Factor S. M., Bouhassira E. E., Lawrence C., Nagel R. L. Hemoglobin C in Transgenic Mice: Effect of Hb C Expression from Founders to Full Mouse Globin Knockouts. Blood Cells Mol. Dis. 2000; 26(4)331–347
  • Olivieri O., Vitoux D., Galactéros F., Bachir D., Blouquit Y., Beuzard Y., Brugnara C. Hemoglobin Variants and Activity of the (K+Cl−) Cotransport System in Human Erythrocytes. Blood 1992; 79: 793–797

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.