Publication Cover
Hemoglobin
international journal for hemoglobin research
Volume 28, 2004 - Issue 4
25
Views
1
CrossRef citations to date
0
Altmetric
Original Article

A Novel Approach to Rapid Determination of βS‐Globin Haplotypes: Sequencing of the Aγ‐IVS‐II Region

, , , , , , & show all
Pages 317-323 | Received 21 Mar 2004, Accepted 21 Jun 2004, Published online: 24 Aug 2009

References

  • Antonarakis S E, Boehm C D, Serjeant G R, Theisen C E, Dover G J, Kazazian H H, Jr. Origin of the βS‐globin gene in Blacks: the contribution of recurrent mutation or gene conversion or both. Proc Natl Acad Sci USA 1984; 81(3)853–856
  • Nagel R L, Fabry M E, Pagnier J, Zohouon I, Wajcman H, Baudin V, Labie D. Hematologically and genetically distinct forms of sickle cell anemia in Africa. NEJM 1985; 312: 880–884
  • Kutlar A, Hattori Y, Bakioglu I, Kutlar F, Kamel K, Huisman T HJ. Hematological observations on Arabian SS patients with a homozygosity or heterozygosity for a βS chromosome with haplotype #31. Hemoglobin 1986; 9(6)545–557
  • Steinberg M H, Hsu E, Nagel R L, Milner P F, Adams J G, Benajmin L, Fryd S, Gillette P, Gilman J, Josifovska O, Helllman‐Erlingsson S, Safaya S, Huey L, Rieder R F. Gender and haplotype effects upon hematological manifestations of adult sickle cell anemia. Am J Hematol 1995; 48(3)175–181
  • Powars D R. Sickle cell anemia: βS gene cluster haplotypes as prognostic indicators of vital organ failure. Semin Hematol 1991; 28(3)202–208
  • Sutton M, Bouhassira E, Nagel R L. Polymerase chain reaction amplification applied to the determination of β‐like globin gene cluster haplotypes. Am J Hematol 1989; 32(1)66–69
  • Lanclos K D, Oner C, Dimovski A J, Gu Y C, Huisman T HJ. Sequence variations in the 5′ flanking and IVS‐II regions of the Gγ‐ and Aγ‐globin genes of βS chromosomes with five different haplotypes. Blood 1991; 77(11)2488–2496
  • Dimovski A J, Oner C, Agarwal S, Gu Y C, Gu L H, Kutlar F, Lanclos K D, Huisman T HJ. Certain mutations observed in the 5′ sequences of the Gγ‐ and Aγ‐globin genes of βS chromosomes are specific for chromosomes with major haplotypes. Acta Haematol 1991; 85(2)79–87
  • Jackson B B, Oruc A C, Kutlar A. A rapid PCR based Non‐radioactive method for the determination of βS haplotypes. Abstracts of Papers, P33. 21st Annual Meeting of the National Sickle Cell Disease Program, Mobile, Alabama, March, 6–91996
  • Poncz M, Solowiejczyk D, Harpel B, Mory Y, Schwartz E, Surrey S. Construction of human gene libraries from small amounts of peripheral blood: analysis of β‐like globin genes. Hemoglobin 1982; 6(1)27–36
  • Hattori Y, Kutlar F, Kutlar A, McKie V C, Huisman T HJ. Haplotypes of βS chromosomes among patients with sickle cell anemia from Georgia. Hemoglobin 1986; 10(6)623–642

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.