References
- Angulo, R., Fulcher, D A., 1998). Measurement of Candida-specific blastogenesis: comparison of carboxyfluorescein succinimidyl ester labeling of T cells, thymidine incorporation, and CD69 expression. Cytometry 34(3):143–151. [PUBMED], [INFOTRIEVE]
- Bernard, S., Pujo-Menjouet, L., Mackey, M C. (2003). Analysis of cell kinetics using a cell division marker: mathematical modeling of experimental data. Biophys. J. 84(5):3414–3424. [PUBMED], [INFOTRIEVE], [CSA]
- Bertoletti, A., Costanzo, A., Chisari, F V., Levrero, M., Artini, M., Sette, A., Penna, A., Giuberti, T., Fiaccadori, F., Ferrari, C. (1994). Cytotoxic T lymphocyte response to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope. J. Exp. Med. 180(3):933–943. [PUBMED], [INFOTRIEVE], [CROSSREF]
- Bertoni, R., Sette, A., Sidney, J., Guidotti, L G., Shapiro, M., Purcell, R., Chisari, F V. (1998). Human class I supertypes and CTL repertoires extend to chimpanzees. J. Immunol. 161:4447–4455., [PUBMED], [INFOTRIEVE]
- Cabatingan, M S., Schmidt, M R., Sen, R., Woodland, R T. (2002). Naive B lymphocytes undergo homeostatic proliferation in response to B cell deficit. J. Immunol. 169:6795–6805. [PUBMED], [INFOTRIEVE]
- Chen, J C., Chang, M L., Muench, M O. (2003). A kinetic study of the murine mixed lymphocyte reaction by 5,6-carboxyfluorescein diacetate succinimidyl ester labeling. J. Immunol. Methods 279(1–2):123–133. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Chisari, F V. (1996). Hepatitis B virus transgenic mice: models of viral immunobiology and pathogenesis. Curr. Top. Microbiol. Immunol. 206:149–173. [PUBMED], [INFOTRIEVE], [CSA]
- Chisari, F V. (1997). Cytotoxic T cells and viral hepatitis. J. Clin. Invest. 99(7):1472–1477. [PUBMED], [INFOTRIEVE], [CSA]
- Chisari, F V., Ferrari, C. (1995). Hepatitis B virus immunopathogenesis. Annu. Rev. Immunol. 13:29–60. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Cote, P J., Gerin, J L. (1995). In vitro activation of woodchuck lymphocytes measured by radiopurine incorporation and interleukin-2 production: implications for modeling immunity and therapy in hepatitis B virus infection. Hepatology 22(3):687–699. [PUBMED], [INFOTRIEVE], [CROSSREF]
- Dengler, T J., Johnson, D R., Pober, J S. (2001). Human vascular endothelial cells stimulate a lower frequency of alloreactive CD8 + pre-CTL and induce less clonal expansion than matching B lymphoblastoid cells: development of a novel limiting dilution analysis method based on CFSE labeling of lymphocytes. J. Immunol. 166(6):3846–3854. [PUBMED], [INFOTRIEVE]
- Dumitriu, I E., Mohr, W., Kolowos, W., Kern, P., Kalden, J R., Herrmann, M. (2001). 5,6-Carboxyfluorescein diacetate succinimidyl ester-labeled apoptotic and necrotic as well as detergent-treated cells can be traced in composite cell samples. Anal. Biochem. 299(2):247–252. [PUBMED], [INFOTRIEVE], [CROSSREF]
- Fujioka, H., Hunt, P J., Rozga, J., Wu, G D., Cramer, D V., Demetriou, A A., Moscioni, A D. (1994). Carboxyfluorescein (CFSE) labelling of hepatocytes for short-term localization following intraportal transplantation. Cell Transplant. 3(5):397–408. [PUBMED], [INFOTRIEVE], [CSA]
- Fulcher, D., Wong, S. (1999). Carboxyfluorescein succinimidyl ester-based proliferative assays for assessment of T cell function in the diagnostic laboratory. Immunol. Cell Biol. 77(6):559–564. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Fulcher, D A., Lyons, A B., Korn, S L., Cook, M C., Koleda, C., Parish, C., Fazekas de St. Groth, B., Basten, A J. (1996). The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help. J. Exp. Med. 183(5):2313–2328. [PUBMED], [INFOTRIEVE], [CROSSREF]
- Givan, A L., Fisher, J L., Waugh, M G., Bercovici, N., Wallace, P K. (2004). Use of cell-tracking dyes to determine proliferation precursor frequencies of antigen-specific T cells. Methods Mol. Biol. 263:109–124. [PUBMED], [INFOTRIEVE]
- Guidotti, L G., Ando, K., Hobbs, M V., Ishikawa, T., Runkel, L., Schreiber, R D., Chisari, F V. (1994). Cytotoxic T lymphocytes inhibit hepatitis B virus gene expression by a noncytolytic mechanism in transgenic mice. Proc. Natl. Acad. Sci. U. S. A. 91(9):3764–3768. [PUBMED], [INFOTRIEVE], [CSA]
- Guidotti, L G., Rochford, R., Chung, J., Shapiro, M., Purcell, R., Chisari, F V. (1999). Viral clearance without destruction of infected cells during acute HBV infection. Science 284(5415):825–829. [PUBMED], [INFOTRIEVE], [CROSSREF]
- Hodgkins, P D., Lee, J H., Lyons, A B. (1996). B cell differentiation and isotype switching is related to division cycle number. J. Exp. Med. 184(1):277–281., [CROSSREF]
- Hodgson, P D., Michalak, T I. (2001). Augmented hepatic interferon gamma expression and T-cell influx characterize acute hepatitis progressing to recovery and residual lifelong virus persistence in experimental adult woodchuck hepatitis virus infection. Hepatology 34(5):1049–1059. [PUBMED], [INFOTRIEVE], [CROSSREF]
- Kreuzfelder, E., Menne, S., Ferencik, S., Roggendorf, M., Grosse-Wilde, H. (1996). Assessment of peripheral blood mononuclear cell proliferation by 2[3H] adenine uptake in the woodchuck model. Clin. Immunol. Immunopathol. 78:223–227. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Lavanchy, D. (2004). Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. J. Viral Hepatitis 11(2):97–107. [CSA], [CROSSREF]
- Lew, Y Y., Michalak, T I. (2001). In vitro and in vivo infectivity and pathogenicity of the lymphoid cell-derived woodchuck hepatitis virus. J. Virol. 75(4):1770–1782. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Li, X., Dancausse, H., Grijalva, I., Oliveira, M., Levi, A D. (2003). Labeling Schwann cells with CFSE-an in vitro and in vivo study. Neurosci. Methods 125(1–2):83–89. [CSA], [CROSSREF]
- Lyons, A B. (2000). Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution. J. Immunol. Methods 243(1–2):147–154. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Lyons, A B., Parish, C R. (1994). Determination of lymphocyte division by flow cytometry. J. Immunol. Methods 171(1):131–137. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Lyons, A B., Hasbold, J., Hodgkin, P D. (2001). Flow cytometric analysis of cell division history using dilution of carboxyfluorescein diacetate succinimidyl ester, a stably integrated fluorescent probe. Methods Cell Biol. 63:375–398. [PUBMED], [INFOTRIEVE]
- Maini, M K., Boni, C., Lee, C K., Larrubia, J R., Reignat, S., Ogg, G S., King, A S., Herberg, J., Gilson, R., Alisa, A., Williams, R., Vergani, D., Naoumov, N V., Ferrari, C., Bertoletti, A J. (2000). The role of virus-specific CD8( + ) cells in liver damage and viral control during persistent hepatitis B virus infection. J. Exp. Med. 191(8):1269–1280. [PUBMED], [INFOTRIEVE], [CROSSREF]
- Mannering, S I., Zhong, J., Cheers, C. (2002). T-cell activation, proliferation and apoptosis in primary Listeria monocytogenes infection. Immunology 106(1):87–95. [PUBMED], [INFOTRIEVE], [CROSSREF]
- Mannering, S I., Morris, J S., Jensen, K P., Purcell, A W., Honeyman, M C., van Endert, P M., Harrison, L C. (2003). A sensitive method for detecting proliferation of rare autoantigen-specific human T cells. J. Immunol. Methods 283(1–2):173–183. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Maschke, J., Menne, S., Jacob, J R., Kreuzfelder, E., Tennant, B C., Roggendorf, M., Grosse-Wilde, H. (2001). Thymidine utilization abnormality in proliferating lymphocytes and hepatocytes of the woodchuck. Vet. Immunol. Immunopathol. 78(3–4):279–296. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Menne, S., Tennant, B C. (1999). Unraveling hepatitis B virus infection of mice and men (and woodchucks and ducks). Nat. Med. 5(10):1125–1126. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Menne, S., Maschke, J., Tolle, T K., Lu, M., Roggendorf, M. (1997). Characterization of T-cell response to woodchuck hepatitis virus core protein and protection of woodchucks from infection by immunization with peptides containing a T-cell epitope. J. Virol. 71(1):65–74. [PUBMED], [INFOTRIEVE], [CSA]
- Menne, S., Maschke, J., Lu, M., Grosse-Wilde, H., Roggendorf, M. (1998). T-Cell response to woodchuck hepatitis virus (WHV) antigens during acute self-limited WHV infection and convalescence and after viral challenge. J. Virol. 72(7):6083–6091. [PUBMED], [INFOTRIEVE], [CSA]
- Menne, S., Roneker, C A., Roggendorf, M., Gerin, J L., Cote, P J. (2002a). Deficiencies in the acute-phase cell-mediated immune response to viral antigens areassociated with development of chronic woodchuck hepatitis virus infection following neonatal inoculation. J. Virol. 76(4):1769–1780. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Menne, S., Roneker, C A., Tennant, B C., Korba, B E., Gerin, J L., Cote, P J. (2002b). Immunogenic effects of woodchuck hepatitis virus surface antigen vaccine in combination with antiviral therapy: breaking of humoral and cellular immune tolerance in chronic woodchuck hepatitis virus infection. Intervirology 45(4–6):237–250. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Michalak, T I. (1998). The woodchuck animal model of hepatitis B. Viral Hepat. Rev. 4:139–165.
- Michalak, T I. (2004). Immunology of hepatitis B virus. In: Colacino, J M., Heinz, B A., eds. Hepatitis Prevention and Treatment. Birkhäuser Verlag, p. 87.
- Michalak, T I., Pasquinelli, C., Guilhot, S., Chisari, F V. (1994). Hepatitis B virus persistence after recovery from acute viral hepatitis. J. Clin. Invest. 93(1):230–239. [PUBMED], [INFOTRIEVE], [CSA]
- Michalak, T I., Pardoe, I U., Coffin, C S., Churchill, N D., Freake, D S., Smith, P., Trelegan, C L. (1999). Occult lifelong persistence of infectious hepadnavirus and residual liver inflammation in woodchucks convalescent from acute viral hepatitis. Hepatology 29(3):928–938. [PUBMED], [INFOTRIEVE], [CROSSREF]
- Michalak, T I., Mulrooney, P M., Coffin, C S. (2004). Low doses of hepadnavirus induce infection of the lymphatic system that does not engage the liver. J. Virol. 78(4):1730–1738. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Miller, M J., Wei, S H., Parker, I., Cahalan, M D. (2002). Two-photon imaging of lymphocyte motility and antigen response in intact lymph node. Science 296(5574):1869–1873. [PUBMED], [INFOTRIEVE], [CROSSREF]
- Moriyama, T., Guilhot, S., Klopchin, K., Moss, B., Pinkert, C A., Palmiter, R D., Brinster, R L., Kanagawa, O., Chisari, F V. (1990). Immunobiology and pathogenesis of hepatocellular injury in hepatitis B virus transgenic mice. Science 248(4953):361–364. [PUBMED], [INFOTRIEVE]
- Mueller-Stahl, K., Kofidis, T., Akhyari, P., Wachsmann, B., Lenz, A., Boublik, J., Heine, M., Muehlfait, V., Haverich, A., Mertsching, H. (2003). Carboxyfluorescein diacetate succinimidyl ester facilitates cell tracing and colocalization studies in bioartificial organ engineering. Int. J. Artif. Organs 26(3):235–240. [PUBMED], [INFOTRIEVE], [CSA]
- Nakamoto, Y., Guidotti, L G., Kuhlen, C V., Fowler, P., Chisari, F V. (1998). Immune pathogenesis of hepatocellular carcinoma. J. Exp. Med. 188(2):341–350. [PUBMED], [INFOTRIEVE], [CROSSREF]
- Nordon, R E., Nakamura, M., Ramirez, C., Odell, R. (1999). Analysis of growth kinetics by division tracking. Immunol. Cell Biol. 77(6):523–529. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Oostendorp, R A., Audet, J., Eaves, C J. (2000). High-resolution tracking of cell division suggests similar cell cycle kinetics of hematopoietic stem cells stimulated in vitro and in vivo. Blood 95(3):855–862. [PUBMED], [INFOTRIEVE], [CSA]
- Parish, C R. (1999). Fluorescent dyes for lymphocyte migration and proliferation studies. Immunol. Cell Biol. 77(6):499–508. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Parish, C R., Warren, H S. (2001). Use of intracellular fluorescent dye CFSE to monitor lymphocyte migration and proliferation. In: Coligan, J M., Kruisbeek, A M., Margulies, D H., Shevach, E M., Strober, W., eds. Current Protocols in Immunology. New York: Greene Publishing Associates and Wiley-Interscience, 4.9.1.
- Rehermann, B., Ferrari, C., Pasquinelli, C., Chisari, F V. (1996). The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despiteactive maintenance of a cytotoxic T-lymphocyte response. Nat. Med. 2(10):1104–1108. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Renno, T., Attinger, A., Locatelli, S., Bakker, T., Vacheron, S., MacDonald, H R. (1999). Cutting edge: apoptosis of superantigen-activated T cells occurs preferentially after a discrete number of cell divisions in vivo. J. Immunol. 162:6312–6315. [PUBMED], [INFOTRIEVE]
- Ristevski, B., Young, A J., Dudler, L., Cahill, R N., Kimpton, W., Washington, E., Hay, J B. (2003). Tracking dendritic cells: use of an in situ method to label all blood leukocytes. Int. Immunol. 15(2):159–165. [PUBMED], [INFOTRIEVE], [CROSSREF]
- Sathiyaseelan, T., Baldwin, C L. (2000). Evaluation of cell replication by bovine T cells in polyclonally activated cultures using carboxyfluorescein succinimidyl ester (CFSE) loading and flow cytometric analysis. Res. Vet. Sci. 69(3):275–281. [PUBMED], [INFOTRIEVE], [CSA]
- Schneider, S., Bruns, A., Moewes, B., Holzknecht, B., Hausdorf, G., Riemekasten, G., Radbruch, A., Hiepe, F., Thiel, A. (2002). Simultaneous cytometric analysis of (auto)antigen-reactive T and B cell proliferation. Immunobiology 206(5):484–495. [PUBMED], [INFOTRIEVE]
- Servet-Delprat, C., Arnaud, S., Jurdic, P., Nataf, S., Grasset, M F., Soulas, C., Domenget, C., Destaing, O., Rivollier, A., Perret, M., Dumontel, C., Hanau, D., Gilmore, G L., Belin, M F., Rabourdin-Combe, C., Mouchiroud, G. (2002). Flt3 + macrophage precursors commit sequentially to osteoclasts, dendritic cells and microglia. BMC Immunol. 3(1):15–26. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Shanmuganathan, S., Waters, J A., Karayiannis, P., Thursz, M., Thomas, H C. (1997). Mapping of the cellular immune responses to woodchuck hepatitis core antigen epitopes in chronically infected woodchucks. J. Med. Virol. 52(2):128–135. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Thimme, R., Wieland, S., Steiger, C., Ghrayeb, J., Reimann, K A., Purcell, R H., Chisari, F V. (2003). CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection. J. Virol. 77(1):68–76. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Usherwood, E J., Crowther, G., Woodland, D L. (1999). Apoptotic cells are generated at every division of in vitro cultured T cell lines. Cell Immunol. 196(2):131–137. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Warren, H S. (1999). Using carboxyfluorescein diacetate succinimidyl ester to monitor human NK cell division: analysis of the effect of activating and inhibitory class I MHC receptors. Immunol. Cell Biol. 77(6):544–551. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Warren, H S., Kinnear, B F. (1999). Quantitative analysis of the effect of CD16 ligation on human NK cell proliferation. J. Immunol. 162(2):735–742. [PUBMED], [INFOTRIEVE]
- Weijer, K., Uittenbogaart, C H., Voordouw, A., Couwenberg, F., Seppen, J., Blom, B., Vyth-Dreese, F A., Spits, H. (2002). Intrathymic and extrathymic development of human plasmacytoid dendritic cell precursors in vivo. Blood 99(8):2752–2759. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- Wieland, S., Thimme, R., Purcell, R H., Chisari, F V. (2004). Genomic analysis of the host response to hepatitis B virus infection. Proc. Natl. Acad. Sci. U. S. A. 101(17):6669–6674. [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
- World Health Organization. (2000). Hepatitis B. World Health Organization Fact Sheet 204 (Revised October 2000). WHO Website 〈http://www.who.int/mediacentre/factsheets/fs204/en/〉.
- Yuki, N., Nagaoka, T., Yamashiro, M., Mochizuki, K., Kaneko, A., Yamamoto, K., Omura, M., Hikiji, K., Kato, M. (2003). Long-term histologic and virologic outcomes of acute self-limited hepatitis B. Hepatology 37(5):1172–1179. [PUBMED], [INFOTRIEVE], [CROSSREF]